#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16611	uniprotkb:O95140	intact:EBI-519866|ensembl:ENSP00000363591|uniprotkb:Q92533|uniprotkb:Q6I9T6|uniprotkb:C0H5Y7	intact:EBI-3324756|uniprotkb:A8K1B3|uniprotkb:O95572|uniprotkb:Q5JXC3|uniprotkb:Q5JXC4|uniprotkb:Q9H131|uniprotkb:Q9NSX8|ensembl:ENSP00000235329|ensembl:ENSP00000416338|ensembl:ENSP00000502151|ensembl:ENSP00000502185|ensembl:ENSP00000502362|ensembl:ENSP00000502404|ensembl:ENSP00000502623|ensembl:ENSP00000501646|ensembl:ENSP00000501716|ensembl:ENSP00000501776	psi-mi:bak_human(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bcl-2-like protein 7(gene name synonym)|uniprotkb:BAK1(gene name)|psi-mi:BAK1(display_short)|uniprotkb:BAK(gene name synonym)|uniprotkb:BCL2L7(gene name synonym)|uniprotkb:CDN1(gene name synonym)	psi-mi:mfn2_human(display_long)|uniprotkb:MFN2(gene name)|psi-mi:MFN2(display_short)|uniprotkb:CPRP1(gene name synonym)|uniprotkb:KIAA0214(gene name synonym)|uniprotkb:Transmembrane GTPase MFN2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Waxman et al. (2009)	mint:MINT-8258212|pubmed:19168699	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8555910|mint:MINT-8258771	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001179.1|ensembl:ENSG00000030110(gene)|ensembl:ENST00000374467(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|mint:Q16611|rcsb pdb:1BXL|rcsb pdb:2IMS|rcsb pdb:2IMT|rcsb pdb:2JBY|rcsb pdb:2JCN|rcsb pdb:2LP8|rcsb pdb:2M5B|rcsb pdb:2XPX|rcsb pdb:2YV6|rcsb pdb:3I1H|rcsb pdb:3QBR|rcsb pdb:4D2L|rcsb pdb:4U2U|rcsb pdb:4U2V|rcsb pdb:4UF1|rcsb pdb:5AJK|rcsb pdb:5FMI|rcsb pdb:5FMK|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX1|rcsb pdb:6ODH|rcsb pdb:6UXM|rcsb pdb:6UXN|rcsb pdb:6UXO|rcsb pdb:6UXP|rcsb pdb:6UXQ|rcsb pdb:6UXR|rcsb pdb:7K02|rcsb pdb:7OFM|rcsb pdb:7OFO|reactome:R-HSA-111452|reactome:R-HSA-111457|reactome:R-HSA-5620971|refseq:XP_011513081.1|dip:DIP-935N|mint:MINT-8258774(identity)	refseq:NP_001121132.1|refseq:NP_055689.1|refseq:XP_005263600.1|refseq:XP_005263602.1|refseq:XP_005263604.1|refseq:XP_005263605.1|ensembl:ENSG00000116688(gene)|ensembl:ENST00000235329(transcript)|ensembl:ENST00000444836(transcript)|ensembl:ENST00000674548(transcript)|ensembl:ENST00000674817(transcript)|ensembl:ENST00000674910(transcript)|ensembl:ENST00000675053(transcript)|ensembl:ENST00000675113(transcript)|ensembl:ENST00000675231(transcript)|ensembl:ENST00000675919(transcript)|ensembl:ENST00000676293(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|interpro:IPR027089|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|mint:O95140|rcsb pdb:6JFK|rcsb pdb:6JFL|rcsb pdb:6JFM|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|dip:DIP-42832N|mint:MINT-8258831(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f11|partial coverage:partial coverage	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/10/21	2018/04/06	rogid:F13a6H/g/tv/Pr90ehCDePpcSB49606	rogid:E54l4ZR9fs6qvZJczOOibxVlJx49606	intact-crc:F20469AAD8E237E1|rigid:M+Zr7NffU8AGh4X2iLjb4i5TPmg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16611	uniprotkb:Q8IWA4	intact:EBI-519866|ensembl:ENSP00000363591|uniprotkb:Q92533|uniprotkb:Q6I9T6|uniprotkb:C0H5Y7	intact:EBI-1048197|uniprotkb:D3DNR6|uniprotkb:O60639|uniprotkb:Q9BZB5|uniprotkb:Q9NWQ2|uniprotkb:O15323|uniprotkb:B2RAR1|ensembl:ENSP00000263969|ensembl:ENSP00000420617|uniprotkb:A0A0C4DFN1	psi-mi:bak_human(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bcl-2-like protein 7(gene name synonym)|uniprotkb:BAK1(gene name)|psi-mi:BAK1(display_short)|uniprotkb:BAK(gene name synonym)|uniprotkb:BCL2L7(gene name synonym)|uniprotkb:CDN1(gene name synonym)	psi-mi:mfn1_human(display_long)|uniprotkb:Transmembrane GTPase MFN1(gene name synonym)|uniprotkb:Fzo homolog(gene name synonym)|uniprotkb:MFN1(gene name)|psi-mi:MFN1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Waxman et al. (2009)	mint:MINT-8258212|pubmed:19168699	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8555910|mint:MINT-8258771	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001179.1|ensembl:ENSG00000030110(gene)|ensembl:ENST00000374467(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|mint:Q16611|rcsb pdb:1BXL|rcsb pdb:2IMS|rcsb pdb:2IMT|rcsb pdb:2JBY|rcsb pdb:2JCN|rcsb pdb:2LP8|rcsb pdb:2M5B|rcsb pdb:2XPX|rcsb pdb:2YV6|rcsb pdb:3I1H|rcsb pdb:3QBR|rcsb pdb:4D2L|rcsb pdb:4U2U|rcsb pdb:4U2V|rcsb pdb:4UF1|rcsb pdb:5AJK|rcsb pdb:5FMI|rcsb pdb:5FMK|rcsb pdb:5VWV|rcsb pdb:5VWW|rcsb pdb:5VWX|rcsb pdb:5VWY|rcsb pdb:5VWZ|rcsb pdb:5VX0|rcsb pdb:5VX1|rcsb pdb:6ODH|rcsb pdb:6UXM|rcsb pdb:6UXN|rcsb pdb:6UXO|rcsb pdb:6UXP|rcsb pdb:6UXQ|rcsb pdb:6UXR|rcsb pdb:7K02|rcsb pdb:7OFM|rcsb pdb:7OFO|reactome:R-HSA-111452|reactome:R-HSA-111457|reactome:R-HSA-5620971|refseq:XP_011513081.1|dip:DIP-935N|mint:MINT-8258774(identity)	refseq:NP_284941.2|ensembl:ENSG00000171109(gene)|ensembl:ENST00000263969(transcript)|ensembl:ENST00000471841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|interpro:IPR027088|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|rcsb pdb:5GNR|rcsb pdb:5GNS|rcsb pdb:5GNT|rcsb pdb:5GNU|rcsb pdb:5GO4|rcsb pdb:5GOE|rcsb pdb:5GOF|rcsb pdb:5GOM|rcsb pdb:5YEW|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0098799"(outer mitochondrial membrane protein complex)|go:"GO:1990613"(mitochondrial membrane fusion)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|refseq:XP_005247653.2|dip:DIP-50289N|mint:MINT-8258773(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f11|partial coverage:partial coverage	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/10/21	2018/04/06	rogid:F13a6H/g/tv/Pr90ehCDePpcSB49606	rogid:JqGBpXDIjWiNwJCt2/DOzE7wFxM9606	intact-crc:F20469AAD8E237E1|rigid:M+Zr7NffU8AGh4X2iLjb4i5TPmg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q80U63	uniprotkb:O08734	intact:EBI-8437663|intact:MINT-8057620|uniprotkb:Q8R535|uniprotkb:A2A7Y7|uniprotkb:Q80XK3|uniprotkb:Q8BHF0|uniprotkb:Q8BKV5|uniprotkb:A8Y5E4|uniprotkb:Q3V3B8|uniprotkb:Q923X2|uniprotkb:Q80WP4|ensembl:ENSMUSP00000030884|ensembl:ENSMUSP00000101340|ensembl:ENSMUSP00000101341	intact:EBI-822441|uniprotkb:E9QM21|uniprotkb:Q8C264|ensembl:ENSMUSP00000077757	psi-mi:mfn2_mouse(display_long)|uniprotkb:Mfn2(gene name)|psi-mi:Mfn2(display_short)|uniprotkb:Kiaa0214(gene name synonym)|uniprotkb:Marf(gene name synonym)|uniprotkb:Hypertension-related protein 1(gene name synonym)|uniprotkb:Mitochondrial assembly regulatory factor(gene name synonym)|uniprotkb:Transmembrane GTPase MFN2(gene name synonym)	psi-mi:bak_mouse(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bak1(gene name)|psi-mi:Bak1(display_short)|uniprotkb:Bak(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Waxman et al. (2009)	mint:MINT-8258212|pubmed:19168699	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8555931|mint:MINT-8258855	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001272849.1|refseq:NP_001272850.1|refseq:NP_001272851.1|refseq:NP_001272852.1|refseq:NP_573464.2|dip:DIP-60970N|refseq:XP_006538672.1|refseq:XP_006538673.1|refseq:XP_006538674.1|ensembl:ENSMUSG00000029020(gene)|ensembl:ENSMUST00000030884(transcript)|ensembl:ENSMUST00000105715(transcript)|ensembl:ENSMUST00000105716(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007006"(mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|interpro:IPR027089|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|mint:Q80U63|reactome:R-MMU-5205685|reactome:R-MMU-9013419|reactome:R-MMU-983231|mint:MINT-8258861(identity)	refseq:NP_031549.2|dip:DIP-29807N|ensembl:ENSMUSG00000057789(gene)|ensembl:ENSMUST00000078691(transcript)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|rcsb pdb:2VOH|rcsb pdb:5FMJ|rcsb pdb:5KTG|rcsb pdb:6MCY|reactome:R-MMU-111452|reactome:R-MMU-111457|reactome:R-MMU-5620971|mint:MINT-8258860(identity)	-	comment:mint	-	comment:mint|figure legend:f10|partial coverage:partial coverage	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2011/10/21	2015/04/29	rogid:7jDQScOD9jxw/I3zBy5mnbjOF0M10090	rogid:T7CFw0SsDVHa+bqgyJSxkaebDBc10090	intact-crc:78C746E8FE4F65F2|rigid:sM1EgMgc+LIXBel9Rt22YC+IGzM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8IWA4	uniprotkb:O08734	intact:EBI-1048197|uniprotkb:D3DNR6|uniprotkb:O60639|uniprotkb:Q9BZB5|uniprotkb:Q9NWQ2|uniprotkb:O15323|uniprotkb:B2RAR1|ensembl:ENSP00000263969|ensembl:ENSP00000420617|uniprotkb:A0A0C4DFN1	intact:EBI-822441|uniprotkb:E9QM21|uniprotkb:Q8C264|ensembl:ENSMUSP00000077757	psi-mi:mfn1_human(display_long)|uniprotkb:Transmembrane GTPase MFN1(gene name synonym)|uniprotkb:Fzo homolog(gene name synonym)|uniprotkb:MFN1(gene name)|psi-mi:MFN1(display_short)	psi-mi:bak_mouse(display_long)|uniprotkb:Apoptosis regulator BAK(gene name synonym)|uniprotkb:Bak1(gene name)|psi-mi:Bak1(display_short)|uniprotkb:Bak(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Waxman et al. (2009)	mint:MINT-8258212|pubmed:19168699	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8555939|mint:MINT-8258922	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_284941.2|ensembl:ENSG00000171109(gene)|ensembl:ENST00000263969(transcript)|ensembl:ENST00000471841(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031306"(intrinsic component of mitochondrial outer membrane)|interpro:IPR027088|interpro:IPR027094|interpro:IPR027417|interpro:IPR030381|rcsb pdb:5GNR|rcsb pdb:5GNS|rcsb pdb:5GNT|rcsb pdb:5GNU|rcsb pdb:5GO4|rcsb pdb:5GOE|rcsb pdb:5GOF|rcsb pdb:5GOM|rcsb pdb:5YEW|reactome:R-HSA-5205685|reactome:R-HSA-9013419|reactome:R-HSA-983231|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0098799"(outer mitochondrial membrane protein complex)|go:"GO:1990613"(mitochondrial membrane fusion)|interpro:IPR006884(Fzo-like conserved region)|interpro:IPR022812|refseq:XP_005247653.2|dip:DIP-50289N|mint:MINT-8258924(identity)	refseq:NP_031549.2|dip:DIP-29807N|ensembl:ENSMUSG00000057789(gene)|ensembl:ENSMUST00000078691(transcript)|go:"GO:0001776"(leukocyte homeostasis)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0002352"(B cell negative selection)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009620"(response to fungus)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010225"(response to UV-C)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046930"(pore complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0051087"(chaperone binding)|go:"GO:0051400"(BH domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060068"(vagina development)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097145"(BAK complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1900103"(positive regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1902262"(apoptotic process involved in blood vessel morphogenesis)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|interpro:IPR026298|interpro:IPR026308|interpro:IPR036834|rcsb pdb:2VOH|rcsb pdb:5FMJ|rcsb pdb:5KTG|rcsb pdb:6MCY|reactome:R-MMU-111452|reactome:R-MMU-111457|reactome:R-MMU-5620971|mint:MINT-8258925(identity)	-	-	-	comment:mint|figure legend:f10|partial coverage:partial coverage	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2011/10/21	2018/04/06	rogid:JqGBpXDIjWiNwJCt2/DOzE7wFxM9606	rogid:T7CFw0SsDVHa+bqgyJSxkaebDBc10090	intact-crc:3A851EF48EC7D608|rigid:Y5D9/Htqm+82C2BCAF17tW9B3i0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)