#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16104 uniprotkb:Q9ULG1 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-4288581 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:supplementary S4|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/02 2014/10/16 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 intact-crc:839CD9B5853C5036|rigid:UzOrRUY7f50woOj890cd1jqTpyE false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P16104 uniprotkb:Q9H9F9 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-769418|uniprotkb:Q86WF7|uniprotkb:Q8IUY5|uniprotkb:Q8N724|uniprotkb:Q9BRN0|uniprotkb:Q9BVB7|ensembl:ENSP00000243903 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:arp5_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-16(gene name synonym)|uniprotkb:ACTR5(gene name)|psi-mi:ACTR5(display_short)|uniprotkb:ARP5(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-3892643 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_079131.3|dip:DIP-34297N|ensembl:ENSG00000101442(gene)|ensembl:ENST00000243903(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR027664|interpro:IPR043129|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:supplementary S3|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/02 2014/10/16 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:ewlnWvZMDIX84KfZ6XIXXm9NBVI9606 intact-crc:0D7ABEDD3853E1E3|rigid:xcV6pnyJ14Z2iT6rMbDzXiA9Qes false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P16104 uniprotkb:Q9ULG1 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-4302824 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - - figure legend:S4|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/02 2014/10/16 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 intact-crc:FAECEDACBE90B071|rigid:UzOrRUY7f50woOj890cd1jqTpyE false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9ULG1 uniprotkb:P16104 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3892655 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K go:"GO:0000785"(chromatin) - - figure legend:Fig 6|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/02 2014/10/16 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 intact-crc:267B6F173F11590B|rigid:28WFh1PMxf3ftEBbd2hygckJXDo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ULG1 uniprotkb:P16104 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3892655 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K go:"GO:0000785"(chromatin) - - figure legend:Fig 6|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/02 2014/10/16 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 intact-crc:267B6F173F11590B|rigid:28WFh1PMxf3ftEBbd2hygckJXDo false - O-phospho-L-serine:140-140 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ULG1 uniprotkb:Q9H9F9 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 intact:EBI-769418|uniprotkb:Q86WF7|uniprotkb:Q8IUY5|uniprotkb:Q8N724|uniprotkb:Q9BRN0|uniprotkb:Q9BVB7|ensembl:ENSP00000243903 psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:arp5_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-16(gene name synonym)|uniprotkb:ACTR5(gene name)|psi-mi:ACTR5(display_short)|uniprotkb:ARP5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3892655 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_079131.3|dip:DIP-34297N|ensembl:ENSG00000101442(gene)|ensembl:ENST00000243903(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR027664|interpro:IPR043129|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0000785"(chromatin) - - figure legend:Fig 6|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/02 2014/10/16 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 rogid:ewlnWvZMDIX84KfZ6XIXXm9NBVI9606 intact-crc:267B6F173F11590B|rigid:28WFh1PMxf3ftEBbd2hygckJXDo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ULG1 uniprotkb:P62805 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3892655 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 go:"GO:0000785"(chromatin) - - figure legend:Fig 6|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/02 2014/10/16 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:267B6F173F11590B|rigid:28WFh1PMxf3ftEBbd2hygckJXDo false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9ULG1 uniprotkb:Q9H9F9 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 intact:EBI-769418|uniprotkb:Q86WF7|uniprotkb:Q8IUY5|uniprotkb:Q8N724|uniprotkb:Q9BRN0|uniprotkb:Q9BVB7|ensembl:ENSP00000243903 psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:arp5_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-16(gene name synonym)|uniprotkb:ACTR5(gene name)|psi-mi:ACTR5(display_short)|uniprotkb:ARP5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Kitayama et al. (2009) pubmed:19014934 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3892662 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_079131.3|dip:DIP-34297N|ensembl:ENSG00000101442(gene)|ensembl:ENST00000243903(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR027664|interpro:IPR043129|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - - figure legend:supplementary S5|comment:Detected in non-chromatin fraction, phosphorylated H2AFX was not detected|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/02 2014/10/16 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 rogid:ewlnWvZMDIX84KfZ6XIXXm9NBVI9606 intact-crc:F5D56898F5590904|rigid:oIhYNWd3mhGDruPCVdYXNPH5BoI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)