#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y5K5 uniprotkb:P28066 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q8NBZ0 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q6P4R8 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P62333 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q13200 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q16186 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P55036 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O00231 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:BgQKXK7gMMihacRCI+g/pBnRN309606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9UNM6 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:iOxE62MMeGx+aqsrir/LukJqeho9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25787 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25789 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O14818 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O96019 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P28074 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q53TQ3 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-769603|uniprotkb:Q6PJU1|uniprotkb:Q6PKA1|uniprotkb:Q9NXD5|uniprotkb:Q6PJC6|uniprotkb:B3KU68|uniprotkb:B9EG77|ensembl:ENSP00000384198|ensembl:ENSP00000490850|intact:EBI-21657516 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:in80d_human(display_long)|uniprotkb:INO80D(gene name)|psi-mi:INO80D(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:XP_011509677.1|refseq:XP_011509678.1|ensembl:ENSP00000384198|ensembl:ENSP00000490850|ensembl:ENSG00000114933(gene)|ensembl:ENSG00000283510(gene)|ensembl:ENST00000403263(transcript)|ensembl:ENST00000636453(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|interpro:IPR025927|mint:Q53TQ3|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_060229.3|refseq:XP_011509672.1|refseq:XP_011509673.1|refseq:XP_011509675.1 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:uAVyU39fDAWdiToA8FknicX0g1E9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P49721 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P62191 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9C086 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q15008 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q6PI98 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-722540|uniprotkb:Q86WR1|uniprotkb:Q8N994|uniprotkb:B4DUI4|uniprotkb:E9PCS7|ensembl:ENSP00000334473 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:in80c_human(display_long)|uniprotkb:INO80C(gene name)|psi-mi:INO80C(display_short)|uniprotkb:C18orf37(gene name synonym)|uniprotkb:IES6 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_919257.2|refseq:NP_001092287.1|ensembl:ENSG00000153391(gene)|ensembl:ENST00000334598(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR013272(YL1 nuclear, C-terminal)|interpro:IPR029525|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:xo40r8gpMPQv1RCH1FC3De6oKF89606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9Y265 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P43686 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P0C1Z6 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-1245626|uniprotkb:G5E9B5|ensembl:ENSP00000375639|ensembl:ENSP00000477775|ensembl:ENSP00000480169|ensembl:ENSP00000480353|ensembl:ENSP00000481443|ensembl:ENSP00000482185|ensembl:ENSP00000482785|ensembl:ENSP00000483417|ensembl:ENSP00000483971|ensembl:ENSP00000484685 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:tfpt_human(display_long)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)|uniprotkb:Protein FB1(gene name synonym)|uniprotkb:INO80F(gene name synonym)|uniprotkb:INO80 complex subunit F(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_037474.1|refseq:NP_001308721.1|ensembl:ENSG00000105619(gene)|ensembl:ENSG00000273833(gene)|ensembl:ENSG00000274073(gene)|ensembl:ENSG00000275086(gene)|ensembl:ENSG00000276022(gene)|ensembl:ENSG00000276263(gene)|ensembl:ENSG00000276296(gene)|ensembl:ENSG00000276323(gene)|ensembl:ENSG00000276504(gene)|ensembl:ENSG00000278161(gene)|ensembl:ENST00000391759(transcript)|ensembl:ENST00000611514(transcript)|ensembl:ENST00000611935(transcript)|ensembl:ENST00000614788(transcript)|ensembl:ENST00000615534(transcript)|ensembl:ENST00000615620(transcript)|ensembl:ENST00000616277(transcript)|ensembl:ENST00000616798(transcript)|ensembl:ENST00000617348(transcript)|ensembl:ENST00000619581(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR033555|mint:P0C1Z6|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P62195 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N go:"GO:0005634"(nucleus) - crc64:29C6410C4A85A7F7 figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9ULG1 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O43242 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q99460 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P48556 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O00487 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25788 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25786 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P28070 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P20618 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9H981 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-769597|uniprotkb:Q9H663|uniprotkb:B3KSW7|uniprotkb:Q8N566|ensembl:ENSP00000336842 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:arp8_human(display_long)|uniprotkb:ACTR8(gene name)|psi-mi:ACTR8(display_short)|uniprotkb:INO80N(gene name synonym)|uniprotkb:INO80 complex subunit N(gene name synonym)|uniprotkb:ARP8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_075050.3|refseq:XP_005265644.1|refseq:XP_011532551.1|ensembl:ENSG00000113812(gene)|ensembl:ENST00000335754(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0051301"(cell division)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027668|interpro:IPR043129|mint:Q9H981|rcsb pdb:4FO0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:9bgkh+pDd9OCLZEW1uWg4fXjBIk9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P28072 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O00232 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9H9F9 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-769418|uniprotkb:Q86WF7|uniprotkb:Q8IUY5|uniprotkb:Q8N724|uniprotkb:Q9BRN0|uniprotkb:Q9BVB7|ensembl:ENSP00000243903 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:arp5_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-16(gene name synonym)|uniprotkb:ACTR5(gene name)|psi-mi:ACTR5(display_short)|uniprotkb:ARP5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_079131.3|dip:DIP-34297N|ensembl:ENSG00000101442(gene)|ensembl:ENST00000243903(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR027664|interpro:IPR043129|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:ewlnWvZMDIX84KfZ6XIXXm9NBVI9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q96EZ8 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P35998 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P51665 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P60900 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25490 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9Y230 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P17980 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606 intact-crc:C46257A3B32FE282|rigid:cOKJwnLGAvIuVlRihG3hXVp+zi4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O14818 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603272|uniprotkb:Q9BR53|uniprotkb:Q9H4K5|uniprotkb:Q9UEU8|uniprotkb:B2R515|uniprotkb:Q5JXJ2|ensembl:ENSP00000359910 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa7_human(display_long)|uniprotkb:PSMA7(gene name)|psi-mi:PSMA7(display_short)|uniprotkb:Proteasome subunit RC6-1(gene name synonym)|uniprotkb:Proteasome subunit XAPC7(gene name synonym)|uniprotkb:HSPC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002783.1|dip:DIP-29363N|ensembl:ENSG00000101182(gene)|ensembl:ENST00000370873(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098794"(postsynapse)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035190|mint:O14818|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:J1M+b+VK02BAn2OnZISjjlmO8dc9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q9UNM6 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:iOxE62MMeGx+aqsrir/LukJqeho9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P51665 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357659|uniprotkb:Q6PKI2|uniprotkb:Q96E97|ensembl:ENSP00000219313|uniprotkb:D3DWS9 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd7_human(display_long)|uniprotkb:PSMD7(gene name)|psi-mi:PSMD7(display_short)|uniprotkb:MOV34L(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN8(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S12(gene name synonym)|uniprotkb:Proteasome subunit p40(gene name synonym)|uniprotkb:Mov34 protein homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002802.2|rcsb pdb:5T0J|ensembl:ENSG00000103035(gene)|ensembl:ENST00000219313(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR033858|interpro:IPR037518|mint:P51665|rcsb pdb:2O95|rcsb pdb:2O96|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-180534|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-195253|reactome:R-HSA-5676590|reactome:R-HSA-202424|reactome:R-HSA-5678895|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-2871837|reactome:R-HSA-5689880|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-6798695|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-68827|reactome:R-HSA-4641258|reactome:R-HSA-68949|reactome:R-HSA-5358346|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27572N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:HJaBTx4pIiSDIArqueuNRvhzVvU9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P28074 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P62333 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357669|uniprotkb:Q92524|uniprotkb:P49719|uniprotkb:Q6IBU3|uniprotkb:B2R975|ensembl:ENSP00000401802 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs10_human(display_long)|uniprotkb:PSMC6(gene name)|psi-mi:PSMC6(display_short)|uniprotkb:SUG2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 6(gene name synonym)|uniprotkb:Proteasome subunit p42(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002797.3|ensembl:ENST00000445930(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000100519(gene)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR032501|interpro:IPR035263|interpro:IPR041569|mint:P62333|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-75815|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-174184|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|dip:DIP-38150N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:QE8jzSEp1bpzhOi/oAAnV18QK249606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q99436 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603319|uniprotkb:Q96AG8|uniprotkb:Q9BWA7|uniprotkb:B4E0P1|uniprotkb:Q5TBG6|ensembl:ENSP00000259457 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb7_human(display_long)|uniprotkb:PSMB7(gene name)|psi-mi:PSMB7(display_short)|uniprotkb:Proteasome subunit Z(gene name synonym)|uniprotkb:Macropain chain Z(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex chain Z(gene name synonym)|uniprotkb:Z(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002790.1|dip:DIP-33843N|ensembl:ENSG00000136930(gene)|ensembl:ENST00000259457(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR024689|interpro:IPR029055|interpro:IPR035216|mint:Q99436|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6HTB|rcsb pdb:6HTC|rcsb pdb:6HTD|rcsb pdb:6HTP|rcsb pdb:6HTR|rcsb pdb:6HUB|rcsb pdb:6HUC|rcsb pdb:6HUQ|rcsb pdb:6HUU|rcsb pdb:6HUV|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:w880QftOor3RdaGvhCup7apz2OM9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q13200 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P49720 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603340|uniprotkb:P31147|uniprotkb:Q0P6J7|uniprotkb:Q96E27|ensembl:ENSP00000483688|ensembl:ENSP00000483956 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb3_human(display_long)|uniprotkb:PSMB3(gene name)|psi-mi:PSMB3(display_short)|uniprotkb:Proteasome theta chain(gene name synonym)|uniprotkb:Proteasome chain 13(gene name synonym)|uniprotkb:Proteasome component C10-II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002786.2|dip:DIP-33846N|ensembl:ENSG00000275903(gene)|ensembl:ENSG00000277791(gene)|ensembl:ENST00000619426(transcript)|ensembl:ENST00000619951(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR033811|mint:P49720|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:H4UDdXV1BaXHp6mEPafNy+Iv8389606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P55036 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P17980 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359720|uniprotkb:Q3B757|ensembl:ENSP00000298852|ensembl:ENSP00000481029|uniprotkb:Q3B865|uniprotkb:Q53HU5|uniprotkb:Q6GPG8|uniprotkb:Q6IBS1|uniprotkb:Q96HD3|uniprotkb:B2R8V1 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs6a_human(display_long)|uniprotkb:PSMC3(gene name)|psi-mi:PSMC3(display_short)|uniprotkb:TBP1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 3(gene name synonym)|uniprotkb:Tat-binding protein 1(gene name synonym)|uniprotkb:Proteasome subunit P50(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002795.2|ensembl:ENSG00000165916(gene)|ensembl:ENST00000298852(transcript)|ensembl:ENST00000619920(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043921"(modulation by host of viral transcription)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035254|interpro:IPR041569|mint:P17980|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|go:"GO:0036402"(proteasome-activating activity)|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-1236978|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-27555N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:CejeauChmqeXNwBYF2cPz7mgMuw9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25787 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603262|uniprotkb:Q9BU45|ensembl:ENSP00000223321|intact:EBI-1237095|uniprotkb:Q6ICS6 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa2_human(display_long)|uniprotkb:PSMA2(gene name)|psi-mi:PSMA2(display_short)|uniprotkb:PSC3(gene name synonym)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:HC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N mint:P25787|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|ensembl:ENSG00000106588(gene)|ensembl:ENST00000223321(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|refseq:NP_002778.1|dip:DIP-29364N|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:COncAMXXqT+zAHA/nK+7dweRg9A9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25789 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359310|uniprotkb:Q8TBD1|uniprotkb:Q53XP2|ensembl:ENSP00000044462|ensembl:ENSP00000453887|uniprotkb:D3DW86|uniprotkb:Q567Q5 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa4_human(display_long)|uniprotkb:PSMA4(gene name)|psi-mi:PSMA4(display_short)|uniprotkb:PSC9(gene name synonym)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:HC9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001096137.1|refseq:NP_002780.1|rcsb pdb:6XMJ|reactome:R-HSA-2467813|reactome:R-HSA-2871837|rcsb pdb:7AWE|reactome:R-HSA-349425|reactome:R-HSA-1169091|reactome:R-HSA-350562|reactome:R-HSA-1234176|reactome:R-HSA-382556|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-450408|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5358346|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000041357(gene)|ensembl:ENST00000044462(transcript)|ensembl:ENST00000559082(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:P25789|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|refseq:NP_001096138.1|refseq:NP_001317605.1|dip:DIP-29365N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:u+wKxvIa9JKb4Zu9K+tnY3d26tw9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q16186 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O00487 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-722193|uniprotkb:O00176|uniprotkb:B3KNW2|ensembl:ENSP00000386541 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psde_human(display_long)|uniprotkb:26S proteasome regulatory subunit RPN11(gene name synonym)|uniprotkb:26S proteasome-associated PAD1 homolog 1(gene name synonym)|uniprotkb:PSMD14(gene name)|psi-mi:PSMD14(display_short)|uniprotkb:POH1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_005796.1|ensembl:ENSG00000115233(gene)|ensembl:ENST00000409682(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0046872"(metal ion binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070628"(proteasome binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR035299|interpro:IPR037518|mint:O00487|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:pSM+755ZbQisR5S0ZivcYBu9Bc49606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P48556 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P28072 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P60900 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357793|uniprotkb:P34062|uniprotkb:Q6IB60|uniprotkb:B2R7J9|uniprotkb:B4DQR4|uniprotkb:B4DXJ9|ensembl:ENSP00000261479 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa6_human(display_long)|uniprotkb:PSMA6(gene name)|psi-mi:PSMA6(display_short)|uniprotkb:PROS27(gene name synonym)|uniprotkb:Proteasome iota chain(gene name synonym)|uniprotkb:Macropain iota chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex iota chain(gene name synonym)|uniprotkb:27 kDa prosomal protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002782.1|refseq:NP_001269162.1|refseq:NP_001269163.1|refseq:XP_016876957.1|refseq:NP_001269161.1|ensembl:ENSG00000100902(gene)|ensembl:ENST00000261479(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0035639"(purine ribonucleoside triphosphate binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034642|mint:P60900|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29367N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:F+Kwr6rnDS3jD53gBGHDIn7HV/89606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P20618 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-372273|uniprotkb:Q9BWA8|ensembl:ENSP00000262193|uniprotkb:B5BU76 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb1_human(display_long)|uniprotkb:PSMB1(gene name)|psi-mi:PSMB1(display_short)|uniprotkb:PSC5(gene name synonym)|uniprotkb:Proteasome component C5(gene name synonym)|uniprotkb:Macropain subunit C5(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C5(gene name synonym)|uniprotkb:Proteasome gamma chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000008018(gene)|ensembl:ENST00000262193(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035202|mint:P20618|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5B|rcsb pdb:5L5D|rcsb pdb:5L5E|rcsb pdb:5L5F|refseq:NP_002784.1|rcsb pdb:5L5H|rcsb pdb:5L5I|rcsb pdb:5L5J|rcsb pdb:5L5O|rcsb pdb:5L5P|rcsb pdb:5L5Q|rcsb pdb:5L5R|rcsb pdb:5L5S|rcsb pdb:5L5T|rcsb pdb:5L5U|rcsb pdb:5L5V|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M2B|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5LF1|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4608870|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-983168|reactome:R-HSA-9604323|dip:DIP-31193N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:DfIS480BUnqbXus9/KoojdkWgw09606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O43242 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q99460 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O00232 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P62191 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357598|uniprotkb:P49014|uniprotkb:Q03527|uniprotkb:Q6IAW0|uniprotkb:Q96AZ3|ensembl:ENSP00000261303|uniprotkb:Q6NW36|uniprotkb:B4DR63 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs4_human(display_long)|uniprotkb:PSMC1(gene name)|psi-mi:PSMC1(display_short)|uniprotkb:26S proteasome AAA-ATPase subunit RPT2(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002793.2|ensembl:ENST00000261303(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|ensembl:ENSG00000100764(gene)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035244|interpro:IPR041569|mint:P62191|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFQ|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-8852276|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_001317141.1|refseq:XP_016876959.1 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:oGEtU7Cv0qversbD3WQgAo5H9pM9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q15008 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P28070 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-603350|uniprotkb:P31148|uniprotkb:Q5SZS5|uniprotkb:Q969L6|uniprotkb:B2R9L3|uniprotkb:Q6IBI4|ensembl:ENSP00000290541 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb4_human(display_long)|uniprotkb:PSMB4(gene name)|psi-mi:PSMB4(display_short)|uniprotkb:Macropain beta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex beta chain(gene name synonym)|uniprotkb:Proteasome chain 3(gene name synonym)|uniprotkb:26 kDa prosomal protein(gene name synonym)|uniprotkb:PROS26(gene name synonym)|uniprotkb:Proteasome beta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002787.2|dip:DIP-33844N|ensembl:ENSG00000159377(gene)|ensembl:ENST00000290541(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR016295(Proteasome endopeptidase complex, beta subunit)|interpro:IPR023333|interpro:IPR029055|mint:P28070|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:drR+ktPXQK9ep6hs7OYb5SmQnXU9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P49721 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359335|uniprotkb:P31145|uniprotkb:Q9BWZ9|uniprotkb:D3DPS0|ensembl:ENSP00000362334 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psb2_human(display_long)|uniprotkb:PSMB2(gene name)|psi-mi:PSMB2(display_short)|uniprotkb:Multicatalytic endopeptidase complex subunit C7-I(gene name synonym)|uniprotkb:Proteasome component C7-I(gene name synonym)|uniprotkb:Macropain subunit C7-I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002785.1|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5GJR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-5689603|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000126067(gene)|ensembl:ENST00000373237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035206|mint:P49721|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|dip:DIP-33848N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:PvXrk6RLayQ1zqmavn1cONfA9/A9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P35998 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25788 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-348380|ensembl:ENSP00000216455|uniprotkb:Q86U83|uniprotkb:Q8N1D8|uniprotkb:Q9BS70|uniprotkb:B2RCK6 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa3_human(display_long)|uniprotkb:PSMA3(gene name)|psi-mi:PSMA3(display_short)|uniprotkb:PSC8(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:HC8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002779.1|refseq:NP_687033.1|ensembl:ENSG00000100567(gene)|ensembl:ENST00000216455(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR037555|mint:P25788|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|rcsb pdb:5DSV|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|rcsb pdb:7E55|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:5T0H|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-174084|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-174113|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|dip:DIP-29366N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:9Er/PY50/GVoCr5yAPXlkfxtP0k9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P28066 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P43686 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P25786 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-359352|uniprotkb:Q9BRV9|uniprotkb:A8K400|uniprotkb:Q53YE8|ensembl:ENSP00000379676 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psa1_human(display_long)|uniprotkb:PSMA1(gene name)|psi-mi:PSMA1(display_short)|uniprotkb:PROS30(gene name synonym)|uniprotkb:PSC2(gene name synonym)|uniprotkb:Proteasome component C2(gene name synonym)|uniprotkb:Macropain subunit C2(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C2(gene name synonym)|uniprotkb:Proteasome nu chain(gene name synonym)|uniprotkb:30 kDa prosomal protein(gene name synonym)|uniprotkb:HC2(gene name synonym)|uniprotkb:NU(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002777.1|refseq:NP_683877.1|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000129084(gene)|ensembl:ENST00000396394(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002376"(immune system process)|go:"GO:0003723"(RNA binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0005844"(polysome)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR035144|mint:P25786|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|dip:DIP-29369N go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:tAADzZ1G9E/0BBeS8vybNx97v7k9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:P62195 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N go:"GO:0005737"(cytoplasm) - crc64:29C6410C4A85A7F7 figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:O00231 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-357816|uniprotkb:O00495|uniprotkb:A8K3I7|uniprotkb:E1P663|uniprotkb:Q53FT5|ensembl:ENSP00000261712|ensembl:ENSP00000393185|ensembl:ENSP00000497128 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:psd11_human(display_long)|uniprotkb:PSMD11(gene name)|psi-mi:PSMD11(display_short)|uniprotkb:26S proteasome regulatory subunit S9(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p44.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_002806.2|refseq:NP_001257411.1|ensembl:ENSG00000108671(gene)|ensembl:ENST00000261712(transcript)|ensembl:ENST00000457654(transcript)|ensembl:ENST00000649012(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:0048863"(stem cell differentiation)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR035295|interpro:IPR036390|interpro:IPR040773|interpro:IPR040780|mint:O00231|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5M32|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 go:"GO:0005737"(cytoplasm) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:BgQKXK7gMMihacRCI+g/pBnRN309606 intact-crc:0BD61E1EACC7A0FC|rigid:8hahjpcq71fR83n+GLFRlMA+c+Y false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q6PI98 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-722540|uniprotkb:Q86WR1|uniprotkb:Q8N994|uniprotkb:B4DUI4|uniprotkb:E9PCS7|ensembl:ENSP00000334473 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:in80c_human(display_long)|uniprotkb:INO80C(gene name)|psi-mi:INO80C(display_short)|uniprotkb:C18orf37(gene name synonym)|uniprotkb:IES6 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_919257.2|refseq:NP_001092287.1|ensembl:ENSG00000153391(gene)|ensembl:ENST00000334598(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR013272(YL1 nuclear, C-terminal)|interpro:IPR029525|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:xo40r8gpMPQv1RCH1FC3De6oKF89606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q9Y5K5 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:P0C1Z6 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-1245626|uniprotkb:G5E9B5|ensembl:ENSP00000375639|ensembl:ENSP00000477775|ensembl:ENSP00000480169|ensembl:ENSP00000480353|ensembl:ENSP00000481443|ensembl:ENSP00000482185|ensembl:ENSP00000482785|ensembl:ENSP00000483417|ensembl:ENSP00000483971|ensembl:ENSP00000484685 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:tfpt_human(display_long)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)|uniprotkb:Protein FB1(gene name synonym)|uniprotkb:INO80F(gene name synonym)|uniprotkb:INO80 complex subunit F(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_037474.1|refseq:NP_001308721.1|ensembl:ENSG00000105619(gene)|ensembl:ENSG00000273833(gene)|ensembl:ENSG00000274073(gene)|ensembl:ENSG00000275086(gene)|ensembl:ENSG00000276022(gene)|ensembl:ENSG00000276263(gene)|ensembl:ENSG00000276296(gene)|ensembl:ENSG00000276323(gene)|ensembl:ENSG00000276504(gene)|ensembl:ENSG00000278161(gene)|ensembl:ENST00000391759(transcript)|ensembl:ENST00000611514(transcript)|ensembl:ENST00000611935(transcript)|ensembl:ENST00000614788(transcript)|ensembl:ENST00000615534(transcript)|ensembl:ENST00000615620(transcript)|ensembl:ENST00000616277(transcript)|ensembl:ENST00000616798(transcript)|ensembl:ENST00000617348(transcript)|ensembl:ENST00000619581(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR033555|mint:P0C1Z6|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q9ULG1 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q6P4R8 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q96EZ8 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:P25490 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q9H981 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-769597|uniprotkb:Q9H663|uniprotkb:B3KSW7|uniprotkb:Q8N566|ensembl:ENSP00000336842 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:arp8_human(display_long)|uniprotkb:ACTR8(gene name)|psi-mi:ACTR8(display_short)|uniprotkb:INO80N(gene name synonym)|uniprotkb:INO80 complex subunit N(gene name synonym)|uniprotkb:ARP8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_075050.3|refseq:XP_005265644.1|refseq:XP_011532551.1|ensembl:ENSG00000113812(gene)|ensembl:ENST00000335754(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0051301"(cell division)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027668|interpro:IPR043129|mint:Q9H981|rcsb pdb:4FO0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:9bgkh+pDd9OCLZEW1uWg4fXjBIk9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q53TQ3 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-769603|uniprotkb:Q6PJU1|uniprotkb:Q6PKA1|uniprotkb:Q9NXD5|uniprotkb:Q6PJC6|uniprotkb:B3KU68|uniprotkb:B9EG77|ensembl:ENSP00000384198|ensembl:ENSP00000490850|intact:EBI-21657516 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:in80d_human(display_long)|uniprotkb:INO80D(gene name)|psi-mi:INO80D(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:XP_011509677.1|refseq:XP_011509678.1|ensembl:ENSP00000384198|ensembl:ENSP00000490850|ensembl:ENSG00000114933(gene)|ensembl:ENSG00000283510(gene)|ensembl:ENST00000403263(transcript)|ensembl:ENST00000636453(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|interpro:IPR025927|mint:Q53TQ3|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_060229.3|refseq:XP_011509672.1|refseq:XP_011509673.1|refseq:XP_011509675.1 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:uAVyU39fDAWdiToA8FknicX0g1E9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:O96019 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q9Y230 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-352939|ensembl:ENSP00000473172|uniprotkb:Q6FIB9|uniprotkb:Q6PK27|uniprotkb:Q9Y361|uniprotkb:B3KQ59|uniprotkb:E7ETE5|intact:EBI-1058527 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:ruvb2_human(display_long)|uniprotkb:RUVBL2(gene name)|psi-mi:RUVBL2(display_short)|uniprotkb:TIP48(gene name synonym)|uniprotkb:TIP49B(gene name synonym)|uniprotkb:CGI-46(orf name)|uniprotkb:48 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49b(gene name synonym)|uniprotkb:Repressing pontin 52(gene name synonym)|uniprotkb:51 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80J(gene name synonym)|uniprotkb:TIP60-associated protein 54-beta(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9Y230|rcsb pdb:2CQA|rcsb pdb:2XSZ|rcsb pdb:3UK6|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6H7X|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|reactome:R-HSA-3214847|ensembl:ENSG00000183207(gene)|ensembl:ENST00000595090(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006457"(protein folding)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0016573"(histone acetylation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|refseq:NP_006657.1|refseq:XP_011524632.1|refseq:NP_001308120.1|dip:DIP-28153N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:APKAWLDCJVULUP3nzqIaSLHKVN49606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q9Y265 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q9H9F9 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-769418|uniprotkb:Q86WF7|uniprotkb:Q8IUY5|uniprotkb:Q8N724|uniprotkb:Q9BRN0|uniprotkb:Q9BVB7|ensembl:ENSP00000243903 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:arp5_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-16(gene name synonym)|uniprotkb:ACTR5(gene name)|psi-mi:ACTR5(display_short)|uniprotkb:ARP5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_079131.3|dip:DIP-34297N|ensembl:ENSG00000101442(gene)|ensembl:ENST00000243903(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0070914"(UV-damage excision repair)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR027664|interpro:IPR043129|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:ewlnWvZMDIX84KfZ6XIXXm9NBVI9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NBZ0 uniprotkb:Q9C086 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) go:"GO:0005634"(nucleus) - - figure legend:1b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2019/08/05 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:A104FC92568C79D3|rigid:uqFhqlAE057iGdD3bv/1cICSglI false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5K5 uniprotkb:Q6P4R8 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894637 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 - - - figure legend:2a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:8A1D8B10CE5AF150|rigid:TrfG2CawtK5uS3FHioVbJO2bq84 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Y5K5 uniprotkb:Q6P4R8 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0096"(pull down) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3894648 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 - - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:88372BFCE71C80E5|rigid:TrfG2CawtK5uS3FHioVbJO2bq84 false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9Y5K5 uniprotkb:Q6P4R8 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0096"(pull down) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3894659 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 - - - figure legend:2c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:9C45272018FDD477|rigid:TrfG2CawtK5uS3FHioVbJO2bq84 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P4R8 uniprotkb:Q9Y5K5 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894670 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:2d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:EED0C82CAE9DD31B|rigid:TrfG2CawtK5uS3FHioVbJO2bq84 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y5K5 uniprotkb:P0C1Z6 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-1245626|uniprotkb:G5E9B5|ensembl:ENSP00000375639|ensembl:ENSP00000477775|ensembl:ENSP00000480169|ensembl:ENSP00000480353|ensembl:ENSP00000481443|ensembl:ENSP00000482185|ensembl:ENSP00000482785|ensembl:ENSP00000483417|ensembl:ENSP00000483971|ensembl:ENSP00000484685 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:tfpt_human(display_long)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)|uniprotkb:Protein FB1(gene name synonym)|uniprotkb:INO80F(gene name synonym)|uniprotkb:INO80 complex subunit F(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894708 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_037474.1|refseq:NP_001308721.1|ensembl:ENSG00000105619(gene)|ensembl:ENSG00000273833(gene)|ensembl:ENSG00000274073(gene)|ensembl:ENSG00000275086(gene)|ensembl:ENSG00000276022(gene)|ensembl:ENSG00000276263(gene)|ensembl:ENSG00000276296(gene)|ensembl:ENSG00000276323(gene)|ensembl:ENSG00000276504(gene)|ensembl:ENSG00000278161(gene)|ensembl:ENST00000391759(transcript)|ensembl:ENST00000611514(transcript)|ensembl:ENST00000611935(transcript)|ensembl:ENST00000614788(transcript)|ensembl:ENST00000615534(transcript)|ensembl:ENST00000615620(transcript)|ensembl:ENST00000616277(transcript)|ensembl:ENST00000616798(transcript)|ensembl:ENST00000617348(transcript)|ensembl:ENST00000619581(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR033555|mint:P0C1Z6|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - - figure legend:3d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606 intact-crc:08613A988491CB14|rigid:QQ7wXkxke57MBmDz0FGCP6jpROM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y5K5 uniprotkb:Q8NBZ0 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894712 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - - figure legend:3d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 intact-crc:D579C89E5BCE7FCF|rigid:ggCmmwZLDamT/boKpC0QGscSQSM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NBZ0 uniprotkb:Q9Y5K5 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894719 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:4c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:59915541C80B06A9|rigid:7PUPU+eNW3gLh8wqD4GF2bqi34U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NBZ0 uniprotkb:Q16186 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894719 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N - - - figure legend:4c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 intact-crc:59915541C80B06A9|rigid:7PUPU+eNW3gLh8wqD4GF2bqi34U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NBZ0 uniprotkb:Q6P4R8 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894719 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 - - - figure legend:4c|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:59915541C80B06A9|rigid:7PUPU+eNW3gLh8wqD4GF2bqi34U false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62195 uniprotkb:Q9Y5K5 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894737 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - crc64:29C6410C4A85A7F7 - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:16B9A4D9166626D8|rigid:+nFrUr6+atPxe2M1y2kiH7CLJ34 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62195 uniprotkb:Q16186 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894737 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N - crc64:29C6410C4A85A7F7 - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 intact-crc:16B9A4D9166626D8|rigid:+nFrUr6+atPxe2M1y2kiH7CLJ34 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P62195 uniprotkb:Q99460 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068 psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894737 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - crc64:29C6410C4A85A7F7 - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606 intact-crc:16B9A4D9166626D8|rigid:+nFrUr6+atPxe2M1y2kiH7CLJ34 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y5K5 uniprotkb:Q9H981 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-769597|uniprotkb:Q9H663|uniprotkb:B3KSW7|uniprotkb:Q8N566|ensembl:ENSP00000336842 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:arp8_human(display_long)|uniprotkb:ACTR8(gene name)|psi-mi:ACTR8(display_short)|uniprotkb:INO80N(gene name synonym)|uniprotkb:INO80 complex subunit N(gene name synonym)|uniprotkb:ARP8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894743 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_075050.3|refseq:XP_005265644.1|refseq:XP_011532551.1|ensembl:ENSG00000113812(gene)|ensembl:ENST00000335754(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0051301"(cell division)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027668|interpro:IPR043129|mint:Q9H981|rcsb pdb:4FO0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:9bgkh+pDd9OCLZEW1uWg4fXjBIk9606 intact-crc:40CDC55197D97D34|rigid:il2M980WsV20ko4/AVu6bYCktQk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NBZ0 uniprotkb:Q9C086 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894747 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) - - - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:0CF6727F72C3B3B8|rigid:1djDXoeyyOp0NLYPs5W0t+RC2b8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NBZ0 uniprotkb:Q9Y5K5 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894747 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:0CF6727F72C3B3B8|rigid:1djDXoeyyOp0NLYPs5W0t+RC2b8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9H981 uniprotkb:Q9Y5K5 intact:EBI-769597|uniprotkb:Q9H663|uniprotkb:B3KSW7|uniprotkb:Q8N566|ensembl:ENSP00000336842 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:arp8_human(display_long)|uniprotkb:ACTR8(gene name)|psi-mi:ACTR8(display_short)|uniprotkb:INO80N(gene name synonym)|uniprotkb:INO80 complex subunit N(gene name synonym)|uniprotkb:ARP8(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894752 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075050.3|refseq:XP_005265644.1|refseq:XP_011532551.1|ensembl:ENSG00000113812(gene)|ensembl:ENST00000335754(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0051301"(cell division)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027668|interpro:IPR043129|mint:Q9H981|rcsb pdb:4FO0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:9bgkh+pDd9OCLZEW1uWg4fXjBIk9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:FD01B3E4249AB814|rigid:RAt963XS6uiLcsKT/6pmbRJcdFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9H981 uniprotkb:Q9C086 intact:EBI-769597|uniprotkb:Q9H663|uniprotkb:B3KSW7|uniprotkb:Q8N566|ensembl:ENSP00000336842 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:arp8_human(display_long)|uniprotkb:ACTR8(gene name)|psi-mi:ACTR8(display_short)|uniprotkb:INO80N(gene name synonym)|uniprotkb:INO80 complex subunit N(gene name synonym)|uniprotkb:ARP8(gene name synonym) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894752 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075050.3|refseq:XP_005265644.1|refseq:XP_011532551.1|ensembl:ENSG00000113812(gene)|ensembl:ENST00000335754(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0051301"(cell division)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027668|interpro:IPR043129|mint:Q9H981|rcsb pdb:4FO0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) - - - figure legend:4e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:9bgkh+pDd9OCLZEW1uWg4fXjBIk9606 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:FD01B3E4249AB814|rigid:RAt963XS6uiLcsKT/6pmbRJcdFU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y5K5 uniprotkb:Q9C086 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894758 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) - - - figure legend:supplement S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 intact-crc:2F6790E5DE9FF3C5|rigid:uxdTEq24yiWvWP+/sgzNmz3m5jk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y5K5 uniprotkb:Q6P4R8 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894758 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 - - - figure legend:supplement S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:2F6790E5DE9FF3C5|rigid:uxdTEq24yiWvWP+/sgzNmz3m5jk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P4R8 uniprotkb:Q9Y5K5 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0096"(pull down) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3894681 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:2e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/05 2014/10/16 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:C746898A285A9618|rigid:TrfG2CawtK5uS3FHioVbJO2bq84 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y5K5 uniprotkb:Q16186 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:"MI:0096"(pull down) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3894686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N - - - figure legend:2e|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/05 2014/10/16 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 intact-crc:CFBC496DE757CEF7|rigid:WXGb/nFrd2Qpvm5Y+zNmim3Uj4w false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16186 uniprotkb:Q9Y5K5 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:3a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2011/05/05 2014/10/16 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:34FBE6788E817CCA|rigid:WXGb/nFrd2Qpvm5Y+zNmim3Uj4w false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6P4R8 uniprotkb:Q9Y5K5 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:3a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2011/05/05 2014/10/16 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:3109A8DBD441C8FE|rigid:TrfG2CawtK5uS3FHioVbJO2bq84 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q16186 uniprotkb:Q9Y5K5 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894732 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - - figure legend:4d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/05 2014/10/16 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 intact-crc:C0DB4DC2AC977490|rigid:i0pTyEYS9UsyttGZ3dYGGzD38jk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q16186 uniprotkb:Q6P4R8 intact:EBI-954387|ensembl:ENSP00000253003|ensembl:ENSP00000478877|uniprotkb:A0PKB1|uniprotkb:Q96FJ7|uniprotkb:Q9H1P2 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:adrm1_human(display_long)|uniprotkb:Adhesion-regulating molecule 1(gene name synonym)|uniprotkb:110 kDa cell membrane glycoprotein(gene name synonym)|uniprotkb:Rpn13 homolog(gene name synonym)|uniprotkb:Proteasome regulatory particle non-ATPase 13(gene name synonym)|uniprotkb:ADRM1(gene name)|psi-mi:ADRM1(display_short)|uniprotkb:GP110(gene name synonym) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yao et al. (2008) pubmed:18922472 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3894732 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000130706(gene)|ensembl:ENST00000253003(transcript)|ensembl:ENST00000491935(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002020"(protease binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043248"(proteasome assembly)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0070628"(proteasome binding)|interpro:IPR006773(Adhesion regulating molecule)|interpro:IPR032368|interpro:IPR038108|interpro:IPR038633|interpro:IPR044867|interpro:IPR044868|mint:Q16186|rcsb pdb:2KQZ|rcsb pdb:2KR0|rcsb pdb:2L5V|rcsb pdb:2MKZ|rcsb pdb:2NBV|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4WLQ|rcsb pdb:4WLR|rcsb pdb:5IRS|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5YMY|rcsb pdb:6CO4|rcsb pdb:6OI4|rcsb pdb:6UYJ|reactome:R-HSA-5689603|reactome:R-HSA-5689880|rcsb pdb:6UYI|refseq:NP_008933.2|refseq:NP_783163.1|refseq:NP_001268366.1|refseq:NP_001268367.1|refseq:XP_005260314.1|dip:DIP-42668N ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 - - - figure legend:4d|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/05 2014/10/16 rogid:XrSLNnNr5Ojm0HkgcnnPube5Lno9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 intact-crc:C0DB4DC2AC977490|rigid:i0pTyEYS9UsyttGZ3dYGGzD38jk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)