#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5T4F4	uniprotkb:Q14318	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Shirane et al. (2008)	pubmed:18459960|imex:IM-16948	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3894019|imex:IM-16948-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	-	-	figure legend:materials and methods|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/05	2014/10/16	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:079D75DD87CD97B7|rigid:OJGI/vY0B2di9JyVsl4t3ORCkxQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5T4F4	uniprotkb:Q14318	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Shirane et al. (2008)	pubmed:18459960|imex:IM-16948	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3894008|imex:IM-16948-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	-	-	figure legend:8A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/05	2014/10/16	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:971CF84039109943|rigid:OJGI/vY0B2di9JyVsl4t3ORCkxQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5T4F4	uniprotkb:Q14318	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Shirane et al. (2008)	pubmed:18459960|imex:IM-16948	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3894030|imex:IM-16948-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	-	-	-	figure legend:8B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2011/05/05	2014/10/16	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	intact-crc:FD85BACC80D59BA1|rigid:OJGI/vY0B2di9JyVsl4t3ORCkxQ	false	flag tag:?-?	ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)