#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0030"(cross-linking study) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3651711 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:2A, 4D and E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:91F952D5154DF35D|rigid:2lELJkUlrP1h1RxloQjlWUSvpG8 false - - - - psi-mi:"MI:0815"(confirmation by molecular weight) psi-mi:"MI:0815"(confirmation by molecular weight) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0096"(pull down) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3651728 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:2B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:5B6D561A119DC65D|rigid:2lELJkUlrP1h1RxloQjlWUSvpG8 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3651739 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - comment:Monomers, dimers, trimers and possibly tetramers have been detected.|figure legend:2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:0860DAD25203E442|rigid:2lELJkUlrP1h1RxloQjlWUSvpG8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0071"(molecular sieving) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3651750 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:2D and E|comment:Monermers, dimers, trimers and tetramers habe been detected.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:4696431506718B1D|rigid:UP+a6UEERQq03Bv615CazoCOdfw false - - 2 0 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0071"(molecular sieving) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3869261 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:2D and E|comment:Monermers, dimers, trimers and tetramers habe been detected.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:204D59BF1CDB06BE|rigid:UP+a6UEERQq03Bv615CazoCOdfw false - - 3 0 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0071"(molecular sieving) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-3869265 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:2D and E|comment:Monermers, dimers, trimers and tetramers habe been detected.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:A04C1CE9598EA6D6|rigid:UP+a6UEERQq03Bv615CazoCOdfw false - - 4 0 psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0030"(cross-linking study) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3651763 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-caco2)|taxid:9606(Human Caucasian colon adenocarcinoma) - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:C811AF6BA5396BC2|rigid:2lELJkUlrP1h1RxloQjlWUSvpG8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0030"(cross-linking study) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3651773 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:D762EB3BBA004A38|rigid:2lELJkUlrP1h1RxloQjlWUSvpG8 false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:P09327 uniprotkb:P09327 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 intact:EBI-746958|intact:EBI-1047253|uniprotkb:B2R9A7|uniprotkb:Q53S11|uniprotkb:Q96AC8|ensembl:ENSP00000248444 psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:vili_human(display_long)|uniprotkb:VIL1(gene name)|psi-mi:VIL1(display_short)|uniprotkb:VIL(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) George et al. (2007) pubmed:17606613 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-3651785 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) refseq:NP_009058.2|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|rcsb pdb:1UNC|rcsb pdb:3FG7|ensembl:ENSG00000127831(gene)|ensembl:ENST00000248444(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border) - - - figure legend:4C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells") - 2011/03/09 2014/10/16 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 rogid:t76IPNZ1RT/zdoXBBeMCZf6OOMg9606 intact-crc:1638AABC4B402693|rigid:2lELJkUlrP1h1RxloQjlWUSvpG8 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)