#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O01498-1 uniprotkb:Q09624 intact:EBI-3835442|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 intact:EBI-2529627|uniprotkb:Q09625|uniprotkb:Q969D4|ensemblmetazoa:ZK945.9.1 psi-mi:o01498-1(display_long)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym)|uniprotkb:C34G6.7(orf name) psi-mi:pkd1_caeel(display_long)|uniprotkb:lov-1(gene name)|psi-mi:lov-1(display_short)|uniprotkb:pkd-1(gene name synonym)|uniprotkb:Polycystin-1(gene name synonym)|uniprotkb:Polycystic kidney disease 1 protein homolog(gene name synonym)|uniprotkb:ZK945.9/ZK945.10(orf name) psi-mi:"MI:0018"(two hybrid) Hu et al. (2007) pubmed:17581863|imex:IM-16946 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3835065|imex:IM-16946-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-331248(isoform-parent)|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene) ensemblmetazoa:WBGene00003058(gene)|ensemblmetazoa:ZK945.9.1(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005929"(cilium)|go:"GO:0007617"(mating behavior)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0060179"(male mating behavior)|go:"GO:0097730"(non-motile cilium)|wormbase:ZK945.9|interpro:IPR000203(GPS)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|refseq:NP_496184.3|interpro:IPR036392|interpro:IPR042060 intact:EBI-3843554(see-also) isoform-comment:No experimental confirmation available. - figure legend:Fig 1B.|caution:The number of amino acids in LOV-1has changed since this paper was published. The numbering for the LOV-1 C-terminal 128 amino acids have been added from the current UniProt version.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/14 2014/10/16 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 rogid:XcL3FOZDC1b/8cBoT7ZIFePtBaQ6239 intact-crc:0C134C56F74E2876|rigid:OWA3+46eXaoS3ZwV6VfnbpXtvYo false sufficient binding region:302-457 sufficient binding region:3157..3157-3284 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q17796 uniprotkb:O01498-1 intact:EBI-319625|ensemblmetazoa:C07G1.5.1|ensemblmetazoa:C07G1.5.2 intact:EBI-3835442|ensemblmetazoa:C34G6.7a.1|ensemblmetazoa:C34G6.7a.2 psi-mi:q17796_caeel(display_long)|uniprotkb:hgrs-1(gene name)|psi-mi:hgrs-1(display_short)|uniprotkb:CELE_C07G1.5(orf name)|uniprotkb:C07G1.5(orf name) psi-mi:o01498-1(display_long)|uniprotkb:stam-1(gene name)|psi-mi:stam-1(display_short)|uniprotkb:pqn-19(gene name synonym)|uniprotkb:"Prion-like-(Q/N-rich) domain-bearing protein 19"(gene name synonym)|uniprotkb:C34G6.7(orf name) psi-mi:"MI:0663"(confocal microscopy) Hu et al. (2007) pubmed:17581863|imex:IM-16946 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3836032|imex:IM-16946-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_501375.2|wormbase:C07G1.5|interpro:IPR024641|ensemblmetazoa:C07G1.5.1(transcript)|ensemblmetazoa:C07G1.5.2(transcript)|ensemblmetazoa:WBGene00004101(gene)|go:"GO:0005769"(early endosome)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0097499"(protein localization to non-motile cilium)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|reactome:R-CEL-182971|reactome:R-CEL-432720|reactome:R-CEL-8856825|reactome:R-CEL-8856828|reactome:R-CEL-917729|reactome:R-CEL-6807004|dip:DIP-24324N|reactome:R-CEL-9013420|reactome:R-CEL-9706019 intact:EBI-331248(isoform-parent)|ensemblmetazoa:C34G6.7a.1(transcript)|ensemblmetazoa:C34G6.7a.2(transcript)|ensemblmetazoa:WBGene00004109(gene) go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0005769"(early endosome) - isoform-comment:No experimental confirmation available. figure legend:Fig 3A.|comment:"In yeast, Drosophila, and mammalian cell culture, the STAM (signal-transducing adaptor molecule) and Hrs (hepatocyte growth factor regulated tyrosine kinase substrate) complex binds and sorts internalized and monoubiquitinated membrane proteins on the early endosome to the multivesicular body (MVB) for lysosomal degradation."|comment:STAM-1 and HGRS-1 expression completely overlaps in cell bodies and ciliary bases of polycystin-expressing neurons.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:6239(caeel-neuron)|taxid:6239(Caenorhabditis elegans neuron) - 2011/03/14 2014/10/16 rogid:Vt+AmRCoka4jybu2GN4eRvLo+6U6239 rogid:dVY1PdSC22+1h1ej7YIsDxtr5zE6239 intact-crc:0D1DA6FEA3998299|rigid:957Ha2g0b2jwOZ/KBlXP2p+JW6Q false green fluorescent protein tag:?-? fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)