#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q5T4F4 uniprotkb:Q14318 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Shirane et al. (2006) pubmed:17082457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3892946 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N - - - figure legend:materials and methods|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/05/04 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:CpZqwry5szPluwNMwWXshCIMUvY9606 intact-crc:5F525604C56111AB|rigid:OJGI/vY0B2di9JyVsl4t3ORCkxQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5T4F4 uniprotkb:P62491 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Shirane et al. (2006) pubmed:17082457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-3892988 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:fig S3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells) - 2011/05/04 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:B48CA676015023C1|rigid:1OuVCy4GugTmiXfIDY3+/Ih08sc false - - - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:Q6P7B7 uniprotkb:P62494 intact:EBI-3893011|ensembl:ENSRNOP00000074613 intact:EBI-2112599|uniprotkb:P24410|uniprotkb:Q9JLX1|ensembl:ENSRNOP00000015598 psi-mi:zfy27_rat(display_long)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:Zfyve27(gene name)|psi-mi:Zfyve27(display_short) psi-mi:rb11a_rat(display_long)|uniprotkb:Rab11a(gene name)|psi-mi:Rab11a(display_short)|uniprotkb:Rab11(gene name synonym)|uniprotkb:24KG(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Shirane et al. (2006) pubmed:17082457 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3893010 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:735177|refseq:NP_954535.2|ensembl:ENSRNOG00000014903(gene)|ensembl:ENSRNOT00000083287(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405 rgd:619762|refseq:NP_112414.1|dip:DIP-46857N|ensembl:ENSRNOG00000011302(gene)|ensembl:ENSRNOT00000015598(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62494|reactome:R-RNO-432040|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-8854214|reactome:R-RNO-8873719|go:"GO:0045335"(phagocytic vesicle) - - - figure legend:3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:10116(rat-pc12)|taxid:10116(Rattus norvegicus PC12 cells) - 2011/05/04 2014/10/16 rogid:NjZ923EoeM2lW6+HtQ+RxkrMihs10116 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU10116 intact-crc:3E0D74928670C36E|rigid:aJhUsBSF95Rn3TFhKr943zNNgTI false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T4F4 uniprotkb:P62491 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shirane et al. (2006) pubmed:17082457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3893676 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:3C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/04 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:CA62022339AFB9C3|rigid:1OuVCy4GugTmiXfIDY3+/Ih08sc false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5T4F4 uniprotkb:P62491 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shirane et al. (2006) pubmed:17082457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3893701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:S4A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/04 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:3CECFC6D0E8D3438|rigid:1OuVCy4GugTmiXfIDY3+/Ih08sc false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P62491 uniprotkb:Q7L804 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 intact:EBI-1049676|uniprotkb:A6NEI4|uniprotkb:Q9Y2F0|intact:EBI-28973556|ensembl:ENSP00000347839|uniprotkb:Q3I768 psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:rfip2_human(display_long)|uniprotkb:NRip11(gene name synonym)|uniprotkb:RAB11FIP2(gene name)|psi-mi:RAB11FIP2(display_short)|uniprotkb:KIAA0941(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Shirane et al. (2006) pubmed:17082457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3893698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N ensembl:ENSP00000347839|ensembl:ENST00000369199|ensembl:ENSP00000358200|refseq:NP_001317096.1|refseq:NP_055719.1|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q7L804|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2K6S|rcsb pdb:3TSO|rcsb pdb:4C4P|rcsb pdb:6S8X|reactome:R-HSA-432040|interpro:IPR019018|ensembl:ENSG00000107560(gene)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0006909"(phagocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|ensembl:ENST00000355624(transcript)|dip:DIP-29139N - - - figure legend:S4A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/05/04 2014/10/16 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 rogid:SM9AVuCsVKsV/VsI6FyQuZyq/xE9606 intact-crc:8C5B46747BAFB629|rigid:SFDDOwIJQTAAq1i55XHvU31dDNQ false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5T4F4 uniprotkb:P62491 intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0096"(pull down) Shirane et al. (2006) pubmed:17082457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3893717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:S4C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/04 2014/10/16 rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:EB87669E0AA73F82|rigid:1OuVCy4GugTmiXfIDY3+/Ih08sc false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q7L804 uniprotkb:P62491 intact:EBI-1049676|uniprotkb:A6NEI4|uniprotkb:Q9Y2F0|intact:EBI-28973556|ensembl:ENSP00000347839|uniprotkb:Q3I768 intact:EBI-745098|uniprotkb:P24410|uniprotkb:Q5TZN9|uniprotkb:Q9JLX1|ensembl:ENSP00000261890|uniprotkb:B2R4B6|uniprotkb:B4DT13 psi-mi:rfip2_human(display_long)|uniprotkb:NRip11(gene name synonym)|uniprotkb:RAB11FIP2(gene name)|psi-mi:RAB11FIP2(display_short)|uniprotkb:KIAA0941(gene name synonym) psi-mi:rb11a_human(display_long)|uniprotkb:YL8(gene name synonym)|uniprotkb:RAB11A(gene name)|psi-mi:RAB11A(display_short)|uniprotkb:RAB11(gene name synonym) psi-mi:"MI:0096"(pull down) Shirane et al. (2006) pubmed:17082457 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3893713 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000347839|ensembl:ENST00000369199|ensembl:ENSP00000358200|refseq:NP_001317096.1|refseq:NP_055719.1|interpro:IPR035892|interpro:IPR037245|interpro:IPR037789|mint:Q7L804|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2K6S|rcsb pdb:3TSO|rcsb pdb:4C4P|rcsb pdb:6S8X|reactome:R-HSA-432040|interpro:IPR019018|ensembl:ENSG00000107560(gene)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0006909"(phagocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035669"(TRAM-dependent toll-like receptor 4 signaling pathway)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|ensembl:ENST00000355624(transcript)|dip:DIP-29139N ensembl:ENSG00000103769(gene)|ensembl:ENST00000261890(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|refseq:NP_001193765.1|refseq:NP_004654.1|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62491|rcsb pdb:1OIV|rcsb pdb:1OIW|rcsb pdb:1OIX|rcsb pdb:1YZK|rcsb pdb:2D7C|rcsb pdb:2GZD|rcsb pdb:2GZH|rcsb pdb:2HV8|rcsb pdb:4C4P|rcsb pdb:4D0L|rcsb pdb:4D0M|rcsb pdb:4LWZ|rcsb pdb:4LX0|rcsb pdb:4UJ3|rcsb pdb:4UJ4|rcsb pdb:4UJ5|rcsb pdb:5C46|rcsb pdb:5C4G|rcsb pdb:5EUQ|rcsb pdb:5EZ5|rcsb pdb:5FBL|rcsb pdb:5FBQ|rcsb pdb:5FBR|rcsb pdb:5FBV|rcsb pdb:5FBW|rcsb pdb:5JCZ|rcsb pdb:6DJL|rcsb pdb:6IXV|reactome:R-HSA-1445148|reactome:R-HSA-432040|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|go:"GO:0019905"(syntaxin binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0030424"(axon)|dip:DIP-29138N - - - figure legend:S4C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/04 2014/10/16 rogid:SM9AVuCsVKsV/VsI6FyQuZyq/xE9606 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU9606 intact-crc:73BAABCAC12D2062|rigid:SFDDOwIJQTAAq1i55XHvU31dDNQ false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)