#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P33535	uniprotkb:P07825	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0018"(two hybrid)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5322012	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	-	-	-	figure legend:no figure|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/12/19	2014/10/16	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	intact-crc:AF43457F640C2D84|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P07825	uniprotkb:P33535	intact:EBI-976085|uniprotkb:Q499R3	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5322001	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	-	-	-	figure legend:no figure|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/12/19	2014/10/16	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	intact-crc:2C284F04428CBA70|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P33535	uniprotkb:P07825	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5322023	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	-	-	-	figure legend:1A|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/12/19	2014/10/16	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	intact-crc:ABC6CB73836D57E5|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P33535	uniprotkb:P07825	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0096"(pull down)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5322034	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	-	-	-	figure legend:1B|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/12/19	2014/10/16	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	intact-crc:D138A9C03C2A0ABF|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P07825	uniprotkb:P33535	intact:EBI-976085|uniprotkb:Q499R3	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5322045	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	-	-	-	figure legend:1c|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/12/19	2014/10/16	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	intact-crc:452679E0F8160FCD|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07825	uniprotkb:P33535	intact:EBI-976085|uniprotkb:Q499R3	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5322056	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	-	-	-	figure legend:2c, 2d.|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/12/19	2014/10/16	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	intact-crc:00342DE5A005AD0B|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:P07825	uniprotkb:P33535	intact:EBI-976085|uniprotkb:Q499R3	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5333092	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	-	-	-	figure legend:4a|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2011/12/19	2014/10/16	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	intact-crc:341131FE722B5C24|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P07825	uniprotkb:P33535	intact:EBI-976085|uniprotkb:Q499R3	intact:EBI-4392569|uniprotkb:Q62846|uniprotkb:Q64064|uniprotkb:Q64120|uniprotkb:Q2TV20|uniprotkb:Q2TV21|uniprotkb:Q4VWM5|uniprotkb:Q4VWM7|uniprotkb:Q4VWX7|uniprotkb:Q4VWX8|ensembl:ENSRNOP00000074079	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:oprm_rat(display_long)|uniprotkb:Oprm1(gene name)|psi-mi:Oprm1(display_short)|uniprotkb:Ror-b(gene name synonym)|uniprotkb:Opioid receptor B(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Liang et al. (2007)	pubmed:17005904	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5322067	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	refseq:NP_001291664.1|refseq:NP_001291666.1|refseq:NP_001291667.1|refseq:NP_001291669.1|rgd:3234|refseq:NP_001033686.1|refseq:NP_001033689.1|refseq:NP_001033690.1|refseq:NP_037203.1|ensembl:ENSRNOG00000018191|refseq:NP_001033688.2|go:"GO:0004979"(beta-endorphin receptor activity)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009314"(response to radiation)|go:"GO:0016020"(membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0031005"(filamin binding)|go:"GO:0031635"(adenylate cyclase-inhibiting opioid receptor signaling pathway)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032094"(response to food)|go:"GO:0032100"(positive regulation of appetite)|go:"GO:0030425"(dendrite)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0038003"(G protein-coupled opioid receptor signaling pathway)|go:"GO:0038047"(morphine receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042755"(eating behavior)|go:"GO:0042923"(neuropeptide binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043951"(negative regulation of cAMP-mediated signaling)|go:"GO:0044849"(estrous cycle)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061358"(negative regulation of Wnt protein secretion)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097444"(spine apparatus)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0106072"(negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:2000310"(regulation of NMDA receptor activity)|interpro:IPR000105(Mu opioid receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001418(Opioid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-111885|reactome:R-RNO-202040|reactome:R-RNO-375276|reactome:R-RNO-418594|ensembl:ENSRNOG00000018191(gene)|ensembl:ENSRNOT00000083308(transcript)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)	-	-	-	figure legend:2e|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|curation depth:mimix curation	taxid:10116(rat-neuron)|taxid:10116(Rattus norvegicus neuronal cell)	-	2011/12/19	2014/10/16	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rogid:wNrY62jBw3FWtANSbP1ygSZuFc410116	intact-crc:AF959B8B6772B8CC|rigid:zKUMMaVfuAQf42DpC2a2HaHlyEY	false	-	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)