#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BSM1 uniprotkb:Q8NHM5 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 go:"GO:0035518"(histone H2A monoubiquitination) - - figure legend:1b and supplemt.table 1|comment:Partial purification of an approximative 800 kDa complex called BCOR complex. A 24 kDa band remains unidentified. The complex is involved in histone H2A monoubiquitination and probably transcriptional repression by recruitment to BCL6 targets|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 intact-crc:16B3E556A229EBE5|rigid:hCkWTeXsQYrC6GPIykDb23O27Sc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q9BSM1 uniprotkb:P63208 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N go:"GO:0035518"(histone H2A monoubiquitination) - - figure legend:1b and supplemt.table 1|comment:Partial purification of an approximative 800 kDa complex called BCOR complex. A 24 kDa band remains unidentified. The complex is involved in histone H2A monoubiquitination and probably transcriptional repression by recruitment to BCL6 targets|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:16B3E556A229EBE5|rigid:hCkWTeXsQYrC6GPIykDb23O27Sc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q9BSM1 uniprotkb:P11142 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N go:"GO:0035518"(histone H2A monoubiquitination) - - figure legend:1b and supplemt.table 1|comment:Partial purification of an approximative 800 kDa complex called BCOR complex. A 24 kDa band remains unidentified. The complex is involved in histone H2A monoubiquitination and probably transcriptional repression by recruitment to BCL6 targets|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 intact-crc:16B3E556A229EBE5|rigid:hCkWTeXsQYrC6GPIykDb23O27Sc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q9BSM1 uniprotkb:Q8N488 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) go:"GO:0035518"(histone H2A monoubiquitination) - - figure legend:1b and supplemt.table 1|comment:Partial purification of an approximative 800 kDa complex called BCOR complex. A 24 kDa band remains unidentified. The complex is involved in histone H2A monoubiquitination and probably transcriptional repression by recruitment to BCL6 targets|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:16B3E556A229EBE5|rigid:hCkWTeXsQYrC6GPIykDb23O27Sc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q9BSM1 uniprotkb:Q99496 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 go:"GO:0035518"(histone H2A monoubiquitination) - - figure legend:1b and supplemt.table 1|comment:Partial purification of an approximative 800 kDa complex called BCOR complex. A 24 kDa band remains unidentified. The complex is involved in histone H2A monoubiquitination and probably transcriptional repression by recruitment to BCL6 targets|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:16B3E556A229EBE5|rigid:hCkWTeXsQYrC6GPIykDb23O27Sc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q9BSM1 uniprotkb:Q06587 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 go:"GO:0035518"(histone H2A monoubiquitination) - - figure legend:1b and supplemt.table 1|comment:Partial purification of an approximative 800 kDa complex called BCOR complex. A 24 kDa band remains unidentified. The complex is involved in histone H2A monoubiquitination and probably transcriptional repression by recruitment to BCL6 targets|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:16B3E556A229EBE5|rigid:hCkWTeXsQYrC6GPIykDb23O27Sc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q9BSM1 uniprotkb:Q6W2J9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N go:"GO:0035518"(histone H2A monoubiquitination) - - figure legend:1b and supplemt.table 1|comment:Partial purification of an approximative 800 kDa complex called BCOR complex. A 24 kDa band remains unidentified. The complex is involved in histone H2A monoubiquitination and probably transcriptional repression by recruitment to BCL6 targets|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:16B3E556A229EBE5|rigid:hCkWTeXsQYrC6GPIykDb23O27Sc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q6W2J9 uniprotkb:Q99496 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955556 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:1b and supplement table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/31 2014/10/16 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:96373E4C2220F0BD|rigid:iqYQw0Xr26bzrYTx/4hKbyPP7YY false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q6W2J9 uniprotkb:P63208 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955556 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:1b and supplement table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/31 2014/10/16 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:96373E4C2220F0BD|rigid:iqYQw0Xr26bzrYTx/4hKbyPP7YY false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q6W2J9 uniprotkb:Q9BSM1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955556 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:1b and supplement table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/31 2014/10/16 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:96373E4C2220F0BD|rigid:iqYQw0Xr26bzrYTx/4hKbyPP7YY false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q6W2J9 uniprotkb:Q06587 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955556 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - - figure legend:1b and supplement table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/05/31 2014/10/16 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:96373E4C2220F0BD|rigid:iqYQw0Xr26bzrYTx/4hKbyPP7YY false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q6W2J9 uniprotkb:Q9BSM1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955584 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:2a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/31 2014/10/16 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:1C286361AE2814EE|rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q9BSM1 uniprotkb:Q06587 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955712 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:F785C209418C2277|rigid:6O2k0fCaSSF7GX1RHIdDvkzspTs false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q99496 uniprotkb:Q9BSM1 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955716 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/31 2014/10/16 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:D719B5E01D5AC96E|rigid:wDbjzmRpMbDnXnIyCuoqqKKyw2M false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q06587 uniprotkb:Q8N488 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955720 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) - - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/31 2014/10/16 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 intact-crc:D8636AA44BBB3597|rigid:FYV3OEzJBh6gZ4MwhgBRBmUsLnk false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8N488 uniprotkb:Q99496 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955724 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/31 2014/10/16 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 intact-crc:085B23ACA4ECC1BB|rigid:9Y2kUGr/jmEvT4yekE1/BzRpwZA false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q99496 uniprotkb:Q06587 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955729 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/31 2014/10/16 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 intact-crc:31E1CD60453F3CE7|rigid:sVWcomLf2mkoq7v0AxWMusV1Utw false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q8NHM5 uniprotkb:P63208 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0096"(pull down) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955735 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:2b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/05/31 2014/10/16 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 intact-crc:97AC1C8250EB63C7|rigid:0FRbGkRgMWg8DkGH0jl8g8AbVFE false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q6W2J9 uniprotkb:Q9BSM1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955707 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:2a|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2011/05/31 2014/10/16 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:EF49E17543665D48|rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NHM5 uniprotkb:Q6W2J9 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955746 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:Fig. 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2011/05/31 2014/10/16 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:D78EF701C70B4902|rigid:cQeHs9djX6DYWVmijwz/Ur8x4z8 false - - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6W2J9 uniprotkb:Q9BSM1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955756 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - - figure legend:3b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2011/05/31 2014/10/16 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 intact-crc:EA23E378B32E8EF6|rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BSM1 uniprotkb:Q6W2J9 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3989161 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:3b|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma) - 2011/05/31 2014/10/16 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:7E8AFA5B4281F217|rigid:RmH3xh6bgTtjJMXhpnJzOfaZAL0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NHM5 uniprotkb:Q6W2J9 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gearhart et al. (2006) pubmed:16943429 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-3955760 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - - figure legend:3b|comment:"KDM2B/FBXL10 (AC Q8NHM5) is found in different bands on the gel which probably correspond to different isoforms. However, the identity of these can not be established"|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|curation depth:mimix curation taxid:9606(human-ramos)|taxid:9606(Human Caucasian Burkitt's lymphoma) - 2011/05/31 2014/10/16 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 intact-crc:879AD51AFC8CD01C|rigid:cQeHs9djX6DYWVmijwz/Ur8x4z8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)