#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P18334 uniprotkb:Q11184 intact:EBI-367861|ensemblmetazoa:B0205.7.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:csk2a_caeel(display_long)|uniprotkb:B0205.7(orf name)|uniprotkb:kin-3(gene name)|psi-mi:kin-3(display_short) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864319|imex:IM-17216-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492811.1|wormbase:B0205.7|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblmetazoa:B0205.7.1(transcript)|ensemblmetazoa:WBGene00002191(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097730"(non-motile cilium)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-CEL-1483191|reactome:R-CEL-201688|reactome:R-CEL-2514853|reactome:R-CEL-445144|reactome:R-CEL-6804756|reactome:R-CEL-6814122|reactome:R-CEL-8934903|reactome:R-CEL-8948751 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:yX9aN9T7phQ4A/hKS8dm+pt4WVQ6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:EAAE6ED18C3D7DE1|rigid:OcGClto6UR3DQCDPX3JYKNrmt4c false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q11184 uniprotkb:Q11184 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864393|imex:IM-17216-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 go:"GO:0005737"(cytoplasm) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:CE783F337BB3B0F1|rigid:wGjntlN/nBhqDoT1GsDDby4pSr4 false green fluorescent protein tag:?-? green fluorescent protein tag:?-? - 0 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q11184 uniprotkb:P28548 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-317777|uniprotkb:O62352|uniprotkb:Q22077|ensemblmetazoa:T01G9.6a.1|ensemblmetazoa:T01G9.6a.2 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:csk2b_caeel(display_long)|uniprotkb:kin-10(gene name)|psi-mi:kin-10(display_short)|uniprotkb:kin-5(gene name synonym)|uniprotkb:T01G9.6(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864385|imex:IM-17216-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 refseq:NP_492254.1|refseq:NP_492255.1|wormbase:T01G9.6a|wormbase:T01G9.6b|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR000704(Casein kinase II, regulatory subunit)|ensemblmetazoa:T01G9.6a.1(transcript)|ensemblmetazoa:T01G9.6a.2(transcript)|ensemblmetazoa:WBGene00002196(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097730"(non-motile cilium)|reactome:R-CEL-6798695|interpro:IPR035991|reactome:R-CEL-1483191|reactome:R-CEL-201688|reactome:R-CEL-2514853|reactome:R-CEL-445144|reactome:R-CEL-6804756|reactome:R-CEL-6814122|reactome:R-CEL-8934903|reactome:R-CEL-8948751 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:ZGeAtVwlI4bqDd612MAvrScqPn86239 intact-crc:A3A6E72ED27F10CB|rigid:7ByKlI6s1HWsyRL6uMdIP8WsP0w false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q11184 uniprotkb:Q22054 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-3844009|ensemblmetazoa:T01C3.6.1|ensemblmetazoa:T01C3.6.2 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:rs16_caeel(display_long)|uniprotkb:rps-16(gene name)|psi-mi:rps-16(display_short)|uniprotkb:T01C3.6(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864417|imex:IM-17216-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 reactome:R-CEL-72706|refseq:NP_506690.1|wormbase:T01C3.6|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR020574|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-72649|ensemblmetazoa:T01C3.6.1(transcript)|ensemblmetazoa:T01C3.6.2(transcript)|ensemblmetazoa:WBGene00004485(gene)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit) - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:s5abj8VcvSuuws+3pyXzQ9TQKC46239 intact-crc:0564D1A9F10E86F3|rigid:1poisDGIB3niRkErgUkgbejOYsc false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q18688 uniprotkb:Q11184 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864453|imex:IM-17216-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:2EC4ED7D1B2DA52C|rigid:vR7X1jIsQAaVLhA0ZDrHTRbM8Y0 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q21556 uniprotkb:Q11184 intact:EBI-3844027|ensemblmetazoa:M18.1a.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:q21556_caeel(display_long)|uniprotkb:M18.1(orf name)|uniprotkb:col-129(gene name)|psi-mi:col-129(display_short)|uniprotkb:CELE_M18.1(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864480|imex:IM-17216-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002486(Nematode cuticle collagen, N-terminal)|interpro:IPR008160(Collagen triple helix repeat)|refseq:NP_502297.1|ensemblmetazoa:M18.1a.1(transcript)|ensemblmetazoa:WBGene00000703(gene)|go:"GO:0042302"(structural constituent of cuticle)|wormbase:M18.1a reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:/898e+g4geGvUik1jlCsZrKmA006239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:AD97BDD09948D7E9|rigid:KpDcNdyfttzSGVDCJ9Bdn+3/b24 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q11184 uniprotkb:G5EDD8 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864911|imex:IM-17216-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 intact-crc:6F1631915833F35A|rigid:Qin0dTEfqZJOf1F1UET/NiCH2uQ false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47991 uniprotkb:Q11184 intact:EBI-316106|ensemblmetazoa:R151.3.1|ensemblmetazoa:R151.3.2|ensemblmetazoa:R151.3.3|ensemblmetazoa:R151.3.4 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:rl6_caeel(display_long)|uniprotkb:rpl-6(gene name)|psi-mi:rpl-6(display_short)|uniprotkb:R151.3(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864918|imex:IM-17216-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-975957|refseq:NP_498584.1|wormbase:R151.3|reactome:R-CEL-72706|ensemblmetazoa:R151.3.1(transcript)|ensemblmetazoa:R151.3.2(transcript)|ensemblmetazoa:R151.3.3(transcript)|ensemblmetazoa:R151.3.4(transcript)|ensemblmetazoa:WBGene00004417(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|reactome:R-CEL-975956|dip:DIP-26565N reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:aXCm4fsV8agyC+8I39VfHUPv8Ck6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:D7550B6F01695D22|rigid:dqdgSzn3m8OkUHqf6WCUp4mqKjw false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q09958 uniprotkb:Q11184 intact:EBI-2412471|ensemblmetazoa:C18A3.3.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:ebp2_caeel(display_long)|uniprotkb:C18A3.3(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864927|imex:IM-17216-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495125.1|wormbase:C18A3.3|interpro:IPR008610(Eukaryotic rRNA processing)|reactome:R-CEL-6791226|ensemblmetazoa:C18A3.3.1(transcript)|ensemblmetazoa:WBGene00015941(gene)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:fxsQB7k7HTMrhovAkWAyejsCc5I6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:D52449C81C6CAF33|rigid:i63NRArAIxsqWUReRKlUN1gaaN4 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P41932 uniprotkb:Q11184 intact:EBI-318108|uniprotkb:Q21537|ensemblmetazoa:M117.2a.1|ensemblmetazoa:M117.2a.2|ensemblmetazoa:M117.2a.3 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:14331_caeel(display_long)|uniprotkb:par-5(gene name)|psi-mi:par-5(display_short)|uniprotkb:ftt-1(gene name synonym)|uniprotkb:M117.2(orf name)|uniprotkb:Partitioning defective protein 5(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864935|imex:IM-17216-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502235.1|reactome:R-CEL-9614399|wormbase:M117.2a|ensemblmetazoa:M117.2a.1(transcript)|ensemblmetazoa:M117.2a.2(transcript)|ensemblmetazoa:M117.2a.3(transcript)|ensemblmetazoa:WBGene00003920(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010286"(heat acclimation)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0035046"(pronuclear migration)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-CEL-392517|reactome:R-CEL-6804114|dip:DIP-27044N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-3769402|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-9013700 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:c18aC7BTcI+D4Mh1q0rXKA5jRL86239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:82BA0C750BC1AC62|rigid:b1slTh2kqtZHPMMIpq2Rxr21yWo false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q11184 uniprotkb:Q20655 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-966073|ensemblmetazoa:F52D10.3a.1|ensemblmetazoa:F52D10.3a.2|ensemblmetazoa:F52D10.3a.3 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:14332_caeel(display_long)|uniprotkb:ftt-2(gene name)|psi-mi:ftt-2(display_short)|uniprotkb:F52D10.3(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864950|imex:IM-17216-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 ensemblmetazoa:F52D10.3a.1(transcript)|ensemblmetazoa:F52D10.3a.2(transcript)|ensemblmetazoa:F52D10.3a.3(transcript)|ensemblmetazoa:WBGene00001502(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0040024"(dauer larval development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|refseq:NP_509939.1|wormbase:F52D10.3a|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-9614399|reactome:R-CEL-392517|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-6804114|dip:DIP-25505N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-3769402|reactome:R-CEL-9013700 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:XSaQshwJqMwJE3F8Az3arYVcgXU6239 intact-crc:C826E6CEC3BC2F85|rigid:HGA5HrqoZjsR2mG/WENcXNReuww false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P31946 uniprotkb:Q11184 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864958|imex:IM-17216-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Fig 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:B1544B19FE7B908C|rigid:4F6y+l8my9RsVDWsS3/HAR31o2Y false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:G5EDZ2 uniprotkb:Q11184 intact:EBI-313698|ensemblmetazoa:T07C4.1.1|ensemblmetazoa:T07C4.1.2 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:umps_caeel(display_long)|uniprotkb:umps-1(gene name)|psi-mi:umps-1(display_short)|uniprotkb:rad-6(gene name synonym)|uniprotkb:T07C4.1(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843995|imex:IM-17216-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q18516(uniprot-removed-ac)|interpro:IPR001754(Orotidine 5'-phosphate decarboxylase, core)|interpro:IPR004467(Orotate phosphoribosyl transferase)|interpro:IPR011060(Ribulose-phosphate binding barrel)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR014732(Orotidine 5'-phosphate decarboxylase, subfamily 1, core)|interpro:IPR023031|refseq:NP_499291.1|mint:G5EDZ2|wormbase:T07C4.1|ensemblmetazoa:T07C4.1.1(transcript)|ensemblmetazoa:T07C4.1.2(transcript)|ensemblmetazoa:WBGene00011559(gene)|go:"GO:0000003"(reproduction)|go:"GO:0002119"(nematode larval development)|go:"GO:0004588"(orotate phosphoribosyltransferase activity)|go:"GO:0004590"(orotidine-5'-phosphate decarboxylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006222"(UMP biosynthetic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009411"(response to UV)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0090727"(positive regulation of brood size)|reactome:R-CEL-500753|interpro:IPR029057|interpro:IPR000836(Phosphoribosyltransferase) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:Cpk0wa1uimBSN+c829/7jJMJdLk6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:934913B28C56941E|rigid:27R8mxLjXW5odPrbZyhWXAdiqXg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34766 uniprotkb:Q11184 intact:EBI-311911|uniprotkb:Q18513|uniprotkb:C9IY23|uniprotkb:Q65ZB9|ensemblmetazoa:C38D4.6a.1|ensemblmetazoa:C38D4.6a.2 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:pal1_caeel(display_long)|uniprotkb:pal-1(gene name)|psi-mi:pal-1(display_short)|uniprotkb:ceh-3(gene name synonym)|uniprotkb:C38D4.6(orf name)|uniprotkb:Homeobox protein ceh-3(gene name synonym)|uniprotkb:Posterior alae in males protein 1(gene name synonym)|uniprotkb:Caudal homolog 1(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843982|imex:IM-17216-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021209.1|refseq:NP_001021210.1|wormbase:C38D4.6a|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001254921.1|ensemblmetazoa:C38D4.6a.1(transcript)|ensemblmetazoa:C38D4.6a.2(transcript)|ensemblmetazoa:WBGene00003912(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|wormbase:C38D4.6b|wormbase:C38D4.6c reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:9bi7B1OJloYwXPwI6AQ2+EfdIpQ6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:FD4ABC8155300759|rigid:HP5V60R+H6MhK7i6Sza8PcfUyP8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18688 uniprotkb:Q11184 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843991|imex:IM-17216-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:535495673EF699DC|rigid:vR7X1jIsQAaVLhA0ZDrHTRbM8Y0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:G5EDD8 uniprotkb:Q11184 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3844040|imex:IM-17216-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:35BE22397207A682|rigid:Qin0dTEfqZJOf1F1UET/NiCH2uQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9XVT3 uniprotkb:Q11184 intact:EBI-3844021|ensemblmetazoa:C15C6.2b.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:q9xvt3_caeel(display_long)|uniprotkb:C15C6.2(orf name)|uniprotkb:CELE_C15C6.2(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843999|imex:IM-17216-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493080.1|wormbase:C15C6.2b|ensemblmetazoa:C15C6.2b.1(transcript)|ensemblmetazoa:WBGene00007601(gene) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:iHmp2f+SZ650/QmiTjlHwQp+Ybs6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:D1F09CCE9A79F714|rigid:0xNCpuNYqu5ixWeVnMtI724KWHM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18020 uniprotkb:Q11184 intact:EBI-3844015|uniprotkb:E0AHB8|ensemblmetazoa:C15C8.3a.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:hrg7_caeel(display_long)|uniprotkb:Heme transporter hrg-7(gene name synonym)|uniprotkb:Heme-responsive gene 7 protein(gene name synonym)|uniprotkb:asp-10(gene name synonym)|uniprotkb:C15C8.3(orf name)|uniprotkb:hrg-7(gene name)|psi-mi:hrg-7(display_short) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843997|imex:IM-17216-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) wormbase:C15C8.3b|wormbase:C15C8.3a|interpro:IPR001461(Peptidase A1)|interpro:IPR021109|interpro:IPR033121|refseq:NP_001256448.1|ensemblmetazoa:C15C8.3a.1(transcript)|ensemblmetazoa:WBGene00007605(gene)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0008219"(cell death)|interpro:IPR034164|refseq:NP_001256449.1|reactome:R-CEL-2132295|reactome:R-CEL-2022377|reactome:R-CEL-5683826 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:Ax1TAQNI5d4KtNCDt24f4Htiycg6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:679F479C2B69D6D9|rigid:Qyq5y+IKkzsaELq6VpfufA5yYpQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q20000 uniprotkb:Q11184 intact:EBI-331559|ensemblmetazoa:F35A5.4.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:q20000_caeel(display_long)|uniprotkb:F35A5.4(orf name)|uniprotkb:CELE_F35A5.4(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3844003|imex:IM-17216-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_508657.2|wormbase:F35A5.4|dip:DIP-25652N|ensemblmetazoa:F35A5.4.1(transcript)|ensemblmetazoa:WBGene00018026(gene)|interpro:IPR003341(Cysteine rich repeat, tripleX) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:3NKLp9MrUg1qvTiwoLuWrfs77q46239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:09B956F4D9F5BA60|rigid:yK/xS88Fj6ik4qfPX0OaoEXFJfM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q21556 uniprotkb:Q11184 intact:EBI-3844027|ensemblmetazoa:M18.1a.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:q21556_caeel(display_long)|uniprotkb:M18.1(orf name)|uniprotkb:col-129(gene name)|psi-mi:col-129(display_short)|uniprotkb:CELE_M18.1(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3844001|imex:IM-17216-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002486(Nematode cuticle collagen, N-terminal)|interpro:IPR008160(Collagen triple helix repeat)|refseq:NP_502297.1|ensemblmetazoa:M18.1a.1(transcript)|ensemblmetazoa:WBGene00000703(gene)|go:"GO:0042302"(structural constituent of cuticle)|wormbase:M18.1a reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:/898e+g4geGvUik1jlCsZrKmA006239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:770FD4646B9F8068|rigid:KpDcNdyfttzSGVDCJ9Bdn+3/b24 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22054 uniprotkb:Q11184 intact:EBI-3844009|ensemblmetazoa:T01C3.6.1|ensemblmetazoa:T01C3.6.2 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:rs16_caeel(display_long)|uniprotkb:rps-16(gene name)|psi-mi:rps-16(display_short)|uniprotkb:T01C3.6(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3843993|imex:IM-17216-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72706|refseq:NP_506690.1|wormbase:T01C3.6|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR020574|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-72649|ensemblmetazoa:T01C3.6.1(transcript)|ensemblmetazoa:T01C3.6.2(transcript)|ensemblmetazoa:WBGene00004485(gene)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:s5abj8VcvSuuws+3pyXzQ9TQKC46239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:AC1EBF62BE76160F|rigid:1poisDGIB3niRkErgUkgbejOYsc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11184 uniprotkb:Q19459 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-319277|uniprotkb:Q6BEU4|ensemblmetazoa:F14E5.2a.1 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:gslg1_caeel(display_long)|uniprotkb:F14E5.2(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865163|imex:IM-17216-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 refseq:NP_001022087.1|refseq:NP_001022088.1|wormbase:F14E5.2a|wormbase:F14E5.2b|ensemblmetazoa:F14E5.2a.1(transcript)|ensemblmetazoa:WBGene00008800(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017134"(fibroblast growth factor binding)|interpro:IPR001893(Cysteine rich repeat)|interpro:IPR017873|interpro:IPR039728|dip:DIP-25688N|reactome:R-CEL-202733 go:"GO:0005737"(cytoplasm) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:Tj9w0B9N3F4fEv1JEb/dZQwqRJw6239 intact-crc:7490877670DED474|rigid:HrUjez9fRUozRTjUDTRQJUd6iFQ false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q11184 uniprotkb:P18334 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-367861|ensemblmetazoa:B0205.7.1 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:csk2a_caeel(display_long)|uniprotkb:B0205.7(orf name)|uniprotkb:kin-3(gene name)|psi-mi:kin-3(display_short) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865118|imex:IM-17216-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 refseq:NP_492811.1|wormbase:B0205.7|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblmetazoa:B0205.7.1(transcript)|ensemblmetazoa:WBGene00002191(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097730"(non-motile cilium)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-CEL-1483191|reactome:R-CEL-201688|reactome:R-CEL-2514853|reactome:R-CEL-445144|reactome:R-CEL-6804756|reactome:R-CEL-6814122|reactome:R-CEL-8934903|reactome:R-CEL-8948751 go:"GO:0005634"(nucleus) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:yX9aN9T7phQ4A/hKS8dm+pt4WVQ6239 intact-crc:D2A3C2B458B7D605|rigid:OcGClto6UR3DQCDPX3JYKNrmt4c false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P34766 uniprotkb:Q11184 intact:EBI-311911|uniprotkb:Q18513|uniprotkb:C9IY23|uniprotkb:Q65ZB9|ensemblmetazoa:C38D4.6a.1|ensemblmetazoa:C38D4.6a.2 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:pal1_caeel(display_long)|uniprotkb:pal-1(gene name)|psi-mi:pal-1(display_short)|uniprotkb:ceh-3(gene name synonym)|uniprotkb:C38D4.6(orf name)|uniprotkb:Homeobox protein ceh-3(gene name synonym)|uniprotkb:Posterior alae in males protein 1(gene name synonym)|uniprotkb:Caudal homolog 1(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865073|imex:IM-17216-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021209.1|refseq:NP_001021210.1|wormbase:C38D4.6a|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001254921.1|ensemblmetazoa:C38D4.6a.1(transcript)|ensemblmetazoa:C38D4.6a.2(transcript)|ensemblmetazoa:WBGene00003912(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|wormbase:C38D4.6b|wormbase:C38D4.6c reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 go:"GO:0005634"(nucleus) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:9bi7B1OJloYwXPwI6AQ2+EfdIpQ6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:1B61B7B1857B0A3B|rigid:HP5V60R+H6MhK7i6Sza8PcfUyP8 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q11184 uniprotkb:P28548 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-317777|uniprotkb:O62352|uniprotkb:Q22077|ensemblmetazoa:T01G9.6a.1|ensemblmetazoa:T01G9.6a.2 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:csk2b_caeel(display_long)|uniprotkb:kin-10(gene name)|psi-mi:kin-10(display_short)|uniprotkb:kin-5(gene name synonym)|uniprotkb:T01G9.6(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865127|imex:IM-17216-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 refseq:NP_492254.1|refseq:NP_492255.1|wormbase:T01G9.6a|wormbase:T01G9.6b|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR000704(Casein kinase II, regulatory subunit)|ensemblmetazoa:T01G9.6a.1(transcript)|ensemblmetazoa:T01G9.6a.2(transcript)|ensemblmetazoa:WBGene00002196(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097730"(non-motile cilium)|reactome:R-CEL-6798695|interpro:IPR035991|reactome:R-CEL-1483191|reactome:R-CEL-201688|reactome:R-CEL-2514853|reactome:R-CEL-445144|reactome:R-CEL-6804756|reactome:R-CEL-6814122|reactome:R-CEL-8934903|reactome:R-CEL-8948751 go:"GO:0016607"(nuclear speck)|go:"GO:0005730"(nucleolus) - - figure legend:Fig 2|comment:KIN-10 was present in nucleoplasm of untransfected LET-756 cells and moved with LET-756 into the nuclear speckles when co-transfected. Upon actinomycin D treatment both LET-756 and KIN-10 formed enlarged speckles and moved to the nucleolus.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:ZGeAtVwlI4bqDd612MAvrScqPn86239 intact-crc:B0F64E8130F96870|rigid:7ByKlI6s1HWsyRL6uMdIP8WsP0w false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q21556 uniprotkb:Q11184 intact:EBI-3844027|ensemblmetazoa:M18.1a.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:q21556_caeel(display_long)|uniprotkb:M18.1(orf name)|uniprotkb:col-129(gene name)|psi-mi:col-129(display_short)|uniprotkb:CELE_M18.1(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865147|imex:IM-17216-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR002486(Nematode cuticle collagen, N-terminal)|interpro:IPR008160(Collagen triple helix repeat)|refseq:NP_502297.1|ensemblmetazoa:M18.1a.1(transcript)|ensemblmetazoa:WBGene00000703(gene)|go:"GO:0042302"(structural constituent of cuticle)|wormbase:M18.1a reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 go:"GO:0005794"(Golgi apparatus) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:/898e+g4geGvUik1jlCsZrKmA006239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:3E66533341F756CE|rigid:KpDcNdyfttzSGVDCJ9Bdn+3/b24 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q11184 uniprotkb:Q22054 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-3844009|ensemblmetazoa:T01C3.6.1|ensemblmetazoa:T01C3.6.2 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:rs16_caeel(display_long)|uniprotkb:rps-16(gene name)|psi-mi:rps-16(display_short)|uniprotkb:T01C3.6(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865138|imex:IM-17216-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 reactome:R-CEL-72706|refseq:NP_506690.1|wormbase:T01C3.6|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR020574|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-72649|ensemblmetazoa:T01C3.6.1(transcript)|ensemblmetazoa:T01C3.6.2(transcript)|ensemblmetazoa:WBGene00004485(gene)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit) go:"GO:0005634"(nucleus) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:s5abj8VcvSuuws+3pyXzQ9TQKC46239 intact-crc:249927A969AD6E76|rigid:1poisDGIB3niRkErgUkgbejOYsc false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P47991 uniprotkb:Q11184 intact:EBI-316106|ensemblmetazoa:R151.3.1|ensemblmetazoa:R151.3.2|ensemblmetazoa:R151.3.3|ensemblmetazoa:R151.3.4 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:rl6_caeel(display_long)|uniprotkb:rpl-6(gene name)|psi-mi:rpl-6(display_short)|uniprotkb:R151.3(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865090|imex:IM-17216-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-975957|refseq:NP_498584.1|wormbase:R151.3|reactome:R-CEL-72706|ensemblmetazoa:R151.3.1(transcript)|ensemblmetazoa:R151.3.2(transcript)|ensemblmetazoa:R151.3.3(transcript)|ensemblmetazoa:R151.3.4(transcript)|ensemblmetazoa:WBGene00004417(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|reactome:R-CEL-975956|dip:DIP-26565N reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 go:"GO:0005654"(nucleoplasm) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:aXCm4fsV8agyC+8I39VfHUPv8Ck6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:FBFD0B03E9790E31|rigid:dqdgSzn3m8OkUHqf6WCUp4mqKjw false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P41932 uniprotkb:Q11184 intact:EBI-318108|uniprotkb:Q21537|ensemblmetazoa:M117.2a.1|ensemblmetazoa:M117.2a.2|ensemblmetazoa:M117.2a.3 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:14331_caeel(display_long)|uniprotkb:par-5(gene name)|psi-mi:par-5(display_short)|uniprotkb:ftt-1(gene name synonym)|uniprotkb:M117.2(orf name)|uniprotkb:Partitioning defective protein 5(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865100|imex:IM-17216-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502235.1|reactome:R-CEL-9614399|wormbase:M117.2a|ensemblmetazoa:M117.2a.1(transcript)|ensemblmetazoa:M117.2a.2(transcript)|ensemblmetazoa:M117.2a.3(transcript)|ensemblmetazoa:WBGene00003920(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010286"(heat acclimation)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0035046"(pronuclear migration)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-CEL-392517|reactome:R-CEL-6804114|dip:DIP-27044N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-3769402|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-9013700 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 go:"GO:0005634"(nucleus) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:c18aC7BTcI+D4Mh1q0rXKA5jRL86239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:6E22993C73F20F37|rigid:b1slTh2kqtZHPMMIpq2Rxr21yWo false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q11184 uniprotkb:Q20655 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-966073|ensemblmetazoa:F52D10.3a.1|ensemblmetazoa:F52D10.3a.2|ensemblmetazoa:F52D10.3a.3 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:14332_caeel(display_long)|uniprotkb:ftt-2(gene name)|psi-mi:ftt-2(display_short)|uniprotkb:F52D10.3(orf name) psi-mi:"MI:0663"(confocal microscopy) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3865109|imex:IM-17216-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 ensemblmetazoa:F52D10.3a.1(transcript)|ensemblmetazoa:F52D10.3a.2(transcript)|ensemblmetazoa:F52D10.3a.3(transcript)|ensemblmetazoa:WBGene00001502(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0040024"(dauer larval development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|refseq:NP_509939.1|wormbase:F52D10.3a|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-9614399|reactome:R-CEL-392517|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-6804114|dip:DIP-25505N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-3769402|reactome:R-CEL-9013700 go:"GO:0005634"(nucleus) - - figure legend:Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells) - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:XSaQshwJqMwJE3F8Az3arYVcgXU6239 intact-crc:5EF3F7BDEB67B68D|rigid:HGA5HrqoZjsR2mG/WENcXNReuww false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q9XVT3 uniprotkb:Q11184 intact:EBI-3844021|ensemblmetazoa:C15C6.2b.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:q9xvt3_caeel(display_long)|uniprotkb:C15C6.2(orf name)|uniprotkb:CELE_C15C6.2(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863544|imex:IM-17216-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_493080.1|wormbase:C15C6.2b|ensemblmetazoa:C15C6.2b.1(transcript)|ensemblmetazoa:WBGene00007601(gene) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 2A|comment:"PAL-1 interacted strongly with LET-756 (two positive tests). For the other interactors, only one test was clearly positive (Table 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:iHmp2f+SZ650/QmiTjlHwQp+Ybs6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:92FA5D97446B359F|rigid:0xNCpuNYqu5ixWeVnMtI724KWHM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11184 uniprotkb:Q21556 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-3844027|ensemblmetazoa:M18.1a.1 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:q21556_caeel(display_long)|uniprotkb:M18.1(orf name)|uniprotkb:col-129(gene name)|psi-mi:col-129(display_short)|uniprotkb:CELE_M18.1(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863531|imex:IM-17216-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 interpro:IPR002486(Nematode cuticle collagen, N-terminal)|interpro:IPR008160(Collagen triple helix repeat)|refseq:NP_502297.1|ensemblmetazoa:M18.1a.1(transcript)|ensemblmetazoa:WBGene00000703(gene)|go:"GO:0042302"(structural constituent of cuticle)|wormbase:M18.1a - - - figure legend:Table 2A|comment:"PAL-1 interacted strongly with LET-756 (two positive tests). For the other interactors, only one test was clearly positive (Table 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:/898e+g4geGvUik1jlCsZrKmA006239 intact-crc:A7044E13EA039F1E|rigid:KpDcNdyfttzSGVDCJ9Bdn+3/b24 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11184 uniprotkb:G5EDD8 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-314583|ensemblmetazoa:F46A9.4.1 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:g5edd8_caeel(display_long)|uniprotkb:skr-2(gene name)|psi-mi:skr-2(display_short)|uniprotkb:CELE_F46A9.4(orf name)|uniprotkb:F46A9.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863535|imex:IM-17216-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 uniprotkb:Q93731(uniprot-removed-ac)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|refseq:NP_492512.1|wormbase:F46A9.4|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0051445"(regulation of meiotic cell cycle)|go:"GO:0097602"(cullin family protein binding)|ensemblmetazoa:F46A9.4.1(transcript)|ensemblmetazoa:WBGene00004808(gene)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010826"(negative regulation of centrosome duplication)|interpro:IPR036296 - - - figure legend:Table 2A|comment:"PAL-1 interacted strongly with LET-756 (two positive tests). For the other interactors, only one test was clearly positive (Table 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:j2g9jI5SVR7+s5r1E3Pk+j/4lgo6239 intact-crc:13CECFD084D315DF|rigid:Qin0dTEfqZJOf1F1UET/NiCH2uQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q22054 uniprotkb:Q11184 intact:EBI-3844009|ensemblmetazoa:T01C3.6.1|ensemblmetazoa:T01C3.6.2 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:rs16_caeel(display_long)|uniprotkb:rps-16(gene name)|psi-mi:rps-16(display_short)|uniprotkb:T01C3.6(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863527|imex:IM-17216-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-72706|refseq:NP_506690.1|wormbase:T01C3.6|interpro:IPR020568|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR020574|reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-72695|reactome:R-CEL-72702|reactome:R-CEL-975956|reactome:R-CEL-975957|reactome:R-CEL-72649|ensemblmetazoa:T01C3.6.1(transcript)|ensemblmetazoa:T01C3.6.2(transcript)|ensemblmetazoa:WBGene00004485(gene)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 2A|comment:"PAL-1 interacted strongly with LET-756 (two positive tests). For the other interactors, only one test was clearly positive (Table 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:s5abj8VcvSuuws+3pyXzQ9TQKC46239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:ED5F209E857C73C2|rigid:1poisDGIB3niRkErgUkgbejOYsc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P34766 uniprotkb:Q11184 intact:EBI-311911|uniprotkb:Q18513|uniprotkb:C9IY23|uniprotkb:Q65ZB9|ensemblmetazoa:C38D4.6a.1|ensemblmetazoa:C38D4.6a.2 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:pal1_caeel(display_long)|uniprotkb:pal-1(gene name)|psi-mi:pal-1(display_short)|uniprotkb:ceh-3(gene name synonym)|uniprotkb:C38D4.6(orf name)|uniprotkb:Homeobox protein ceh-3(gene name synonym)|uniprotkb:Posterior alae in males protein 1(gene name synonym)|uniprotkb:Caudal homolog 1(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863515|imex:IM-17216-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001021209.1|refseq:NP_001021210.1|wormbase:C38D4.6a|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001254921.1|ensemblmetazoa:C38D4.6a.1(transcript)|ensemblmetazoa:C38D4.6a.2(transcript)|ensemblmetazoa:WBGene00003912(gene)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001712"(ectodermal cell fate commitment)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0030154"(cell differentiation)|go:"GO:0042693"(muscle cell fate commitment)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|wormbase:C38D4.6b|wormbase:C38D4.6c reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 2A|comment:"PAL-1 interacted strongly with LET-756 (two positive tests). For the other interactors, only one test was clearly positive (Table 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:9bi7B1OJloYwXPwI6AQ2+EfdIpQ6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:034DCFB720F626E8|rigid:HP5V60R+H6MhK7i6Sza8PcfUyP8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q18688 uniprotkb:Q11184 intact:EBI-313329|ensemblmetazoa:C47E8.5.1|ensemblmetazoa:C47E8.5.2|ensemblmetazoa:C47E8.5.3|ensemblmetazoa:C47E8.5.4 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:hsp90_caeel(display_long)|uniprotkb:daf-21(gene name)|psi-mi:daf-21(display_short)|uniprotkb:Abnormal dauer formation protein 21(gene name synonym)|uniprotkb:C47E8.5(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863523|imex:IM-17216-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_506626.1|wormbase:C47E8.5|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990634"(protein phosphatase 5 binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|rcsb pdb:4GQT|rcsb pdb:4I2Z|go:"GO:0042802"(identical protein binding)|ensemblmetazoa:C47E8.5.1(transcript)|ensemblmetazoa:C47E8.5.2(transcript)|ensemblmetazoa:C47E8.5.3(transcript)|ensemblmetazoa:C47E8.5.4(transcript)|ensemblmetazoa:WBGene00000915(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006935"(chemotaxis)|go:"GO:0007049"(cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0040024"(dauer larval development)|reactome:R-CEL-5675482|dip:DIP-25037N|reactome:R-CEL-1474151|reactome:R-CEL-203615|reactome:R-CEL-3371497|reactome:R-CEL-3371511|reactome:R-CEL-3371571|reactome:R-CEL-5218920|reactome:R-CEL-6798695|reactome:R-CEL-8863795|reactome:R-CEL-8937144|reactome:R-CEL-8939211|reactome:R-CEL-9009391|reactome:R-CEL-3371568|reactome:R-CEL-9652282 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:Table 2A|comment:"PAL-1 interacted strongly with LET-756 (two positive tests). For the other interactors, only one test was clearly positive (Table 2A)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:goxx/LuRQ1JdMht41DCZyulxDpg6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:9FF8D456E26727E1|rigid:vR7X1jIsQAaVLhA0ZDrHTRbM8Y0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P28548 uniprotkb:Q11184 intact:EBI-317777|uniprotkb:O62352|uniprotkb:Q22077|ensemblmetazoa:T01G9.6a.1|ensemblmetazoa:T01G9.6a.2 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:csk2b_caeel(display_long)|uniprotkb:kin-10(gene name)|psi-mi:kin-10(display_short)|uniprotkb:kin-5(gene name synonym)|uniprotkb:T01G9.6(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863949|imex:IM-17216-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492254.1|refseq:NP_492255.1|wormbase:T01G9.6a|wormbase:T01G9.6b|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR000704(Casein kinase II, regulatory subunit)|ensemblmetazoa:T01G9.6a.1(transcript)|ensemblmetazoa:T01G9.6a.2(transcript)|ensemblmetazoa:WBGene00002196(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097730"(non-motile cilium)|reactome:R-CEL-6798695|interpro:IPR035991|reactome:R-CEL-1483191|reactome:R-CEL-201688|reactome:R-CEL-2514853|reactome:R-CEL-445144|reactome:R-CEL-6804756|reactome:R-CEL-6814122|reactome:R-CEL-8934903|reactome:R-CEL-8948751 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:ZGeAtVwlI4bqDd612MAvrScqPn86239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:72F61E2FA59A5BE0|rigid:7ByKlI6s1HWsyRL6uMdIP8WsP0w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P18334 uniprotkb:Q11184 intact:EBI-367861|ensemblmetazoa:B0205.7.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:csk2a_caeel(display_long)|uniprotkb:B0205.7(orf name)|uniprotkb:kin-3(gene name)|psi-mi:kin-3(display_short) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863940|imex:IM-17216-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_492811.1|wormbase:B0205.7|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|ensemblmetazoa:B0205.7.1(transcript)|ensemblmetazoa:WBGene00002191(gene)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034606"(response to hermaphrodite contact)|go:"GO:0034608"(vulval location)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097730"(non-motile cilium)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-CEL-1483191|reactome:R-CEL-201688|reactome:R-CEL-2514853|reactome:R-CEL-445144|reactome:R-CEL-6804756|reactome:R-CEL-6814122|reactome:R-CEL-8934903|reactome:R-CEL-8948751 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:yX9aN9T7phQ4A/hKS8dm+pt4WVQ6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:B050A232F2FDCB75|rigid:OcGClto6UR3DQCDPX3JYKNrmt4c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11184 uniprotkb:P11141 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-2006327|uniprotkb:P91135|ensemblmetazoa:C37H5.8.1 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:hsp6_caeel(display_long)|uniprotkb:hsp-6(gene name)|psi-mi:hsp-6(display_short)|uniprotkb:hsp70f(gene name synonym)|uniprotkb:C37H5.8(orf name)|uniprotkb:Heat shock 70 kDa protein F, mitochondrial(gene name synonym)|uniprotkb:mot-2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863974|imex:IM-17216-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 interpro:IPR043129|refseq:NP_504291.1|wormbase:C37H5.8|interpro:IPR012725(Chaperone DnaK)|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|rcsb pdb:3DQG|reactome:R-CEL-3371453|interpro:IPR029047|interpro:IPR029048|ensemblmetazoa:C37H5.8.1(transcript)|ensemblmetazoa:WBGene00002010(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding) - - - figure legend:TABLE 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:mr6DFT7Fpkxrq2KsDDyXWGxU/+E6239 intact-crc:75303E892604CA5B|rigid:eOJTNbK8mzQ49HVzqrji4ytoBno false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q19459 uniprotkb:Q11184 intact:EBI-319277|uniprotkb:Q6BEU4|ensemblmetazoa:F14E5.2a.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:gslg1_caeel(display_long)|uniprotkb:F14E5.2(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3863987|imex:IM-17216-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001022087.1|refseq:NP_001022088.1|wormbase:F14E5.2a|wormbase:F14E5.2b|ensemblmetazoa:F14E5.2a.1(transcript)|ensemblmetazoa:WBGene00008800(gene)|go:"GO:0000139"(Golgi membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017134"(fibroblast growth factor binding)|interpro:IPR001893(Cysteine rich repeat)|interpro:IPR017873|interpro:IPR039728|dip:DIP-25688N|reactome:R-CEL-202733 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:Tj9w0B9N3F4fEv1JEb/dZQwqRJw6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:CCD86310819F4173|rigid:HrUjez9fRUozRTjUDTRQJUd6iFQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q09958 uniprotkb:Q11184 intact:EBI-2412471|ensemblmetazoa:C18A3.3.1 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:ebp2_caeel(display_long)|uniprotkb:C18A3.3(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864031|imex:IM-17216-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_495125.1|wormbase:C18A3.3|interpro:IPR008610(Eukaryotic rRNA processing)|reactome:R-CEL-6791226|ensemblmetazoa:C18A3.3.1(transcript)|ensemblmetazoa:WBGene00015941(gene)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:fxsQB7k7HTMrhovAkWAyejsCc5I6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:0C337AE9E9816491|rigid:i63NRArAIxsqWUReRKlUN1gaaN4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P47991 uniprotkb:Q11184 intact:EBI-316106|ensemblmetazoa:R151.3.1|ensemblmetazoa:R151.3.2|ensemblmetazoa:R151.3.3|ensemblmetazoa:R151.3.4 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:rl6_caeel(display_long)|uniprotkb:rpl-6(gene name)|psi-mi:rpl-6(display_short)|uniprotkb:R151.3(orf name) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864037|imex:IM-17216-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-156827|reactome:R-CEL-1799339|reactome:R-CEL-72689|reactome:R-CEL-975957|refseq:NP_498584.1|wormbase:R151.3|reactome:R-CEL-72706|ensemblmetazoa:R151.3.1(transcript)|ensemblmetazoa:R151.3.2(transcript)|ensemblmetazoa:R151.3.3(transcript)|ensemblmetazoa:R151.3.4(transcript)|ensemblmetazoa:WBGene00004417(gene)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|reactome:R-CEL-975956|dip:DIP-26565N reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:aXCm4fsV8agyC+8I39VfHUPv8Ck6239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:CFC2F032F28A7F58|rigid:dqdgSzn3m8OkUHqf6WCUp4mqKjw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P41932 uniprotkb:Q11184 intact:EBI-318108|uniprotkb:Q21537|ensemblmetazoa:M117.2a.1|ensemblmetazoa:M117.2a.2|ensemblmetazoa:M117.2a.3 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:14331_caeel(display_long)|uniprotkb:par-5(gene name)|psi-mi:par-5(display_short)|uniprotkb:ftt-1(gene name synonym)|uniprotkb:M117.2(orf name)|uniprotkb:Partitioning defective protein 5(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864050|imex:IM-17216-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_502235.1|reactome:R-CEL-9614399|wormbase:M117.2a|ensemblmetazoa:M117.2a.1(transcript)|ensemblmetazoa:M117.2a.2(transcript)|ensemblmetazoa:M117.2a.3(transcript)|ensemblmetazoa:WBGene00003920(gene)|go:"GO:0000003"(reproduction)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0001708"(cell fate specification)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0009949"(polarity specification of anterior/posterior axis)|go:"GO:0010070"(zygote asymmetric cell division)|go:"GO:0010286"(heat acclimation)|go:"GO:0030590"(first cell cycle pseudocleavage)|go:"GO:0035046"(pronuclear migration)|go:"GO:0045167"(asymmetric protein localization involved in cell fate determination)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-CEL-392517|reactome:R-CEL-6804114|dip:DIP-27044N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-3769402|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-9013700 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:c18aC7BTcI+D4Mh1q0rXKA5jRL86239 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:CED03EE2A1E45585|rigid:b1slTh2kqtZHPMMIpq2Rxr21yWo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11184 uniprotkb:Q20655 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-966073|ensemblmetazoa:F52D10.3a.1|ensemblmetazoa:F52D10.3a.2|ensemblmetazoa:F52D10.3a.3 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:14332_caeel(display_long)|uniprotkb:ftt-2(gene name)|psi-mi:ftt-2(display_short)|uniprotkb:F52D10.3(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864054|imex:IM-17216-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 ensemblmetazoa:F52D10.3a.1(transcript)|ensemblmetazoa:F52D10.3a.2(transcript)|ensemblmetazoa:F52D10.3a.3(transcript)|ensemblmetazoa:WBGene00001502(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0040024"(dauer larval development)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|refseq:NP_509939.1|wormbase:F52D10.3a|reactome:R-CEL-165159|reactome:R-CEL-166208|reactome:R-CEL-170968|reactome:R-CEL-2028269|reactome:R-CEL-450385|reactome:R-CEL-5673000|reactome:R-CEL-5674135|reactome:R-CEL-5675221|reactome:R-CEL-9614399|reactome:R-CEL-392517|reactome:R-CEL-430116|reactome:R-CEL-450604|reactome:R-CEL-6804114|dip:DIP-25505N|reactome:R-CEL-5625740|reactome:R-CEL-75035|reactome:R-CEL-3769402|reactome:R-CEL-9013700 - - - figure legend:TABLE 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:XSaQshwJqMwJE3F8Az3arYVcgXU6239 intact-crc:090844C8F6AAD003|rigid:HGA5HrqoZjsR2mG/WENcXNReuww false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P31946 uniprotkb:Q11184 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864066|imex:IM-17216-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:DFA5F17FD4AE578D|rigid:4F6y+l8my9RsVDWsS3/HAR31o2Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11184 uniprotkb:Q9UIS9 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-867196|uniprotkb:K7ELI2|uniprotkb:Q9UNZ9|uniprotkb:K7EQZ4|uniprotkb:K7ESN0|uniprotkb:A4UTZ0|uniprotkb:O15248|uniprotkb:O95241|uniprotkb:Q7Z7B5|uniprotkb:Q8N4W4|uniprotkb:Q9UNZ6|uniprotkb:Q9UNZ7|uniprotkb:Q9UNZ8|uniprotkb:B4DXJ5|uniprotkb:E9PEC5|intact:EBI-10977266|ensembl:ENSP00000269468|ensembl:ENSP00000372407|ensembl:ENSP00000467017 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:mbd1_human(display_long)|uniprotkb:CXXC3(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD1(gene name synonym)|uniprotkb:Protein containing methyl-CpG-binding domain 1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 3(gene name synonym)|uniprotkb:MBD1(gene name)|psi-mi:MBD1(display_short)|uniprotkb:PCM1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864110|imex:IM-17216-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 refseq:NP_001191065.1|refseq:NP_001191068.1|refseq:NP_001191071.1|refseq:NP_001191072.1|refseq:NP_001191080.1|refseq:NP_002375.1|refseq:NP_056669.2|refseq:NP_056670.2|refseq:NP_056671.2|refseq:NP_056723.2|refseq:XP_011524295.1|refseq:XP_016881249.1|refseq:XP_016881259.1|refseq:XP_016881260.1|refseq:XP_016881265.1|refseq:XP_011524296.1|refseq:XP_011524308.1|refseq:NP_001191066.1|refseq:NP_001191067.1|refseq:NP_001191069.1|refseq:NP_001191070.1|refseq:XP_005258328.1|ensembl:ENSG00000141644(gene)|ensembl:ENST00000269468(transcript)|ensembl:ENST00000382948(transcript)|ensembl:ENST00000591416(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR016177(DNA-binding, integrase-type)|mint:Q9UIS9|rcsb pdb:1D9N|rcsb pdb:1IG4|rcsb pdb:4D4W|rcsb pdb:5W9Q|rcsb pdb:6D1T|reactome:R-HSA-3899300 - - - figure legend:TABLE 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:I6StIYNuO8jT6ZR1YxoZnzDrP/I9606 intact-crc:7EF7FC584D8DB081|rigid:/RCbDiS5HWwEQTci4OTyRucuIUI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q11184 uniprotkb:Q13347 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539 psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864114|imex:IM-17216-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N - - - figure legend:TABLE 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 rogid:fogC6nSNmIynV2ziHZboT9laA3M9606 intact-crc:BB46C2BD9AE419BC|rigid:Jf3K2trp41Aur23SGOO6pybSLmE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8WUP2 uniprotkb:Q11184 intact:EBI-3864120|uniprotkb:B3KNY0|uniprotkb:Q5VVE0|uniprotkb:Q5VVE1|uniprotkb:Q8IX23|uniprotkb:Q96T00|uniprotkb:Q9UFD6|ensembl:ENSP00000364921|ensembl:ENSP00000364926 intact:EBI-3843983|uniprotkb:O76831|ensemblmetazoa:C05D11.4.1 psi-mi:fbli1_human(display_long)|uniprotkb:FBLIM1(gene name)|psi-mi:FBLIM1(display_short)|uniprotkb:FBLP1(gene name synonym)|uniprotkb:Migfilin(gene name synonym)|uniprotkb:Mitogen-inducible 2-interacting protein(gene name synonym) psi-mi:le756_caeel(display_long)|uniprotkb:let-756(gene name)|psi-mi:let-756(display_short)|uniprotkb:Lethal protein 756(gene name synonym)|uniprotkb:C05D11.4(orf name) psi-mi:"MI:0018"(two hybrid) Popovici et al. (2006) pubmed:16672054|imex:IM-17216 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3864165|imex:IM-17216-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710767.1|refseq:XP_006710768.1|refseq:XP_011539918.1|refseq:XP_011539919.1|refseq:NP_001019386.1|refseq:NP_001019387.1|refseq:NP_060026.2|refseq:XP_005245957.1|refseq:XP_005245958.1|refseq:XP_005245959.1|refseq:XP_005245960.1|refseq:XP_005245966.1|ensembl:ENST00000332305|ensembl:ENSP00000364920|ensembl:ENSP00000364921|ensembl:ENSP00000364926|ensembl:ENST00000441801|ensembl:ENSP00000416387|refseq:XP_016857008.1|refseq:XP_016857009.1|refseq:XP_016857010.1|refseq:XP_016857011.1|refseq:XP_016857012.1|refseq:XP_016857013.1|refseq:XP_016857014.1|ensembl:ENSG00000162458(gene)|ensembl:ENST00000375766(transcript)|ensembl:ENST00000375771(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0031005"(filamin binding)|go:"GO:0033623"(regulation of integrin activation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071944"(cell periphery)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001781(Zinc finger, LIM-type)|rcsb pdb:2K9U|rcsb pdb:2W0P|rcsb pdb:4P3W|reactome:R-HSA-446353 reactome:R-CEL-3000170|refseq:NP_498403.1|wormbase:C05D11.4|interpro:IPR008996(Cytokine, IL-1-like)|interpro:IPR002209(Heparin-binding growth factor/Fibroblast growth factor)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002119"(nematode larval development)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008083"(growth factor activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031345"(negative regulation of cell projection organization)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|ensemblmetazoa:C05D11.4.1(transcript)|ensemblmetazoa:WBGene00002881(gene)|reactome:R-CEL-5658623 - - - figure legend:TABLE 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/03/22 2014/10/16 rogid:jhOy0Oo9EyNavyHXYGOAT0VtrNY9606 rogid:dpNC3mWmERNdueUJC/O1R9OO52A6239 intact-crc:3A5E55C3B087223F|rigid:H1JVk3B+wd297EiMOtzxmb1AbQQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)