#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P39676	uniprotkb:Q07540	intact:EBI-6905|uniprotkb:Q6B1W6|uniprotkb:Q9C1R6|uniprotkb:D6VV14|ensemblfungi:YGR234W	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:fhp_yeast(display_long)|uniprotkb:YHB1(gene name)|psi-mi:YHB1(display_short)|uniprotkb:YHB(gene name synonym)|uniprotkb:YGR234W(locus name)|uniprotkb:G8572(orf name)|uniprotkb:Flavohemoglobin(gene name synonym)|uniprotkb:Hemoglobin-like protein(gene name synonym)|uniprotkb:Nitric oxide dioxygenase(gene name synonym)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0018"(two hybrid)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953030|imex:IM-17231-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011750.1|sgd:S000003466|mint:P39676|dip:DIP-1355N|ensemblfungi:YGR234W(gene)|ensemblfungi:YGR234W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016966"(nitric oxide reductase activity)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0071949"(FAD binding)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000971(Globin, subset)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023950|interpro:IPR039261	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	-	crc64:8AF1DE3280220D56	crc64:AB1FF7478EF0E5D6	figure legend:No Figure|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:IfSyxMXBw3eqwWjAFb87dab9Ixo559292	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:11805826B669F7C1|rigid:JjcO9+BoSEUhMxRQQuG5SAqYGng	false	sufficient binding region:106-399	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39676	uniprotkb:Q07540	intact:EBI-6905|uniprotkb:Q6B1W6|uniprotkb:Q9C1R6|uniprotkb:D6VV14|ensemblfungi:YGR234W	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:fhp_yeast(display_long)|uniprotkb:YHB1(gene name)|psi-mi:YHB1(display_short)|uniprotkb:YHB(gene name synonym)|uniprotkb:YGR234W(locus name)|uniprotkb:G8572(orf name)|uniprotkb:Flavohemoglobin(gene name synonym)|uniprotkb:Hemoglobin-like protein(gene name synonym)|uniprotkb:Nitric oxide dioxygenase(gene name synonym)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953079|imex:IM-17231-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011750.1|sgd:S000003466|mint:P39676|dip:DIP-1355N|ensemblfungi:YGR234W(gene)|ensemblfungi:YGR234W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008941"(nitric oxide dioxygenase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016966"(nitric oxide reductase activity)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046210"(nitric oxide catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0071500"(cellular response to nitrosative stress)|go:"GO:0071949"(FAD binding)|go:"GO:1902170"(cellular response to reactive nitrogen species)|interpro:IPR000971(Globin, subset)|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR017927|interpro:IPR017938|interpro:IPR023950|interpro:IPR039261	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	-	crc64:8AF1DE3280220D56	crc64:AB1FF7478EF0E5D6	figure legend:Fig. 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:IfSyxMXBw3eqwWjAFb87dab9Ixo559292	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:9C540E81D64FE365|rigid:JjcO9+BoSEUhMxRQQuG5SAqYGng	false	ha tag:n-n	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q00711	uniprotkb:Q07540	intact:EBI-5851|ensemblfungi:YKL148C|uniprotkb:D6VX49	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:sdha_yeast(display_long)|uniprotkb:SDH1(gene name)|psi-mi:SDH1(display_short)|uniprotkb:SDHA(gene name synonym)|uniprotkb:YKL148C(locus name)|uniprotkb:YKL602(orf name)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953101|imex:IM-17231-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009055"(electron transfer activity)|go:"GO:0031966"(mitochondrial membrane)|ensemblfungi:YKL148C(gene)|ensemblfungi:YKL148C_mRNA(transcript)|go:"GO:0000104"(succinate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|reactome:R-SCE-71403|refseq:NP_012774.1|sgd:S000001631|dip:DIP-5853N|go:"GO:0045333"(cellular respiration)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:1ORZ|rcsb pdb:1PB4	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	-	crc64:A657E440B8ED58E2	crc64:AB1FF7478EF0E5D6	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:EQ2NFEjW4fXnH8bzfRi60S6oBJk559292	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:FE9552C734C80022|rigid:573eiW6xB3aiRS/2/xkl/Jd/9vk	false	ha tag:n-n|sufficient binding region:153-485(IPR003953)	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P21801	uniprotkb:Q07540	intact:EBI-5856|uniprotkb:D6VXW5|ensemblfungi:YLL041C	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:sdhb_yeast(display_long)|uniprotkb:YLL041C(locus name)|uniprotkb:SDH2(gene name)|psi-mi:SDH2(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDHB(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953135|imex:IM-17231-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-SCE-71403|refseq:NP_013059.1|sgd:S000003964|dip:DIP-5856N|ensemblfungi:YLL041C(gene)|ensemblfungi:YLL041C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0045333"(cellular respiration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|rcsb pdb:1ORZ|rcsb pdb:1PB4	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	-	crc64:C14170F3670F6930	crc64:AB1FF7478EF0E5D6	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:yOyapuZFBAAoPmfWDZX5Cpogj00559292	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:B014407BEFD96077|rigid:YdJbpPCxtioDIUn0uq5ii/TOXY0	false	ha tag:n-n|sufficient binding region:40-266	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12480	uniprotkb:Q07540	intact:EBI-6697|uniprotkb:D6W415|ensemblfungi:YPR004C	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	psi-mi:etfa_yeast(display_long)|uniprotkb:YPR004C(locus name)|uniprotkb:YP9723.04C(orf name)|uniprotkb:LPZ4C(orf name)|uniprotkb:AIM45(gene name)|psi-mi:AIM45(display_short)|uniprotkb:Altered inheritance rate of mitochondria protein 45(gene name synonym)	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953221|imex:IM-17231-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015329.1|sgd:S000006208|reactome:R-SCE-611105|dip:DIP-5574N|ensemblfungi:YPR004C(gene)|ensemblfungi:YPR004C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	-	-	crc64:AB1FF7478EF0E5D6	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:kaSvom6SX6GH0mwDhaW6/STRvMY559292	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	intact-crc:A37957E991B81FB5|rigid:uc7CUMs23uglcJ6DreqmU7VKn9c	false	sufficient binding region:39-344|ha tag:n-n	lexa dna binding domain:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q07540	uniprotkb:P42940	intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W	intact:EBI-6701|uniprotkb:D6VUZ0|ensemblfungi:YGR207C	psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name)	psi-mi:etfb_yeast(display_long)|uniprotkb:YGR207C(locus name)|uniprotkb:G7742(orf name)|uniprotkb:CIR1(gene name)|psi-mi:CIR1(display_short)|uniprotkb:Changed intracellular redox state protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953231|imex:IM-17231-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding)	refseq:NP_011723.1|sgd:S000003439|dip:DIP-3865N|mint:P42940|ensemblfungi:YGR207C(gene)|ensemblfungi:YGR207C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|interpro:IPR000049(Electron transfer flavoprotein, beta-subunit, core)|interpro:IPR012255(Electron transfer flavoprotein, beta subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR033948|reactome:R-SCE-611105	-	crc64:AB1FF7478EF0E5D6	-	figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292	rogid:dqlrCBivdG4U/15fa9VOY/EceMg559292	intact-crc:46560D184B0F98B4|rigid:IvFYn53aP+66ISkYl9Wpcg2K/Dc	false	lexa dna binding domain:c-c	ha tag:n-n|sufficient binding region:36-261	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P31040	uniprotkb:Q16595	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	intact:EBI-949340|ensembl:ENSP00000419243|uniprotkb:O15545|uniprotkb:O95656|uniprotkb:Q15294|uniprotkb:Q5VZ01|uniprotkb:A8MXJ6|uniprotkb:C9JJ89	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:frda_human(display_long)|uniprotkb:Friedreich ataxia protein(gene name synonym)|uniprotkb:FXN(gene name)|psi-mi:FXN(display_short)|uniprotkb:FRDA(gene name synonym)|uniprotkb:X25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953246|imex:IM-17231-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	ensembl:ENSG00000165060(gene)|ensembl:ENST00000484259(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010039"(response to iron ion)|go:"GO:0010722"(regulation of ferrochelatase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0019230"(proprioception)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0051349"(positive regulation of lyase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904231"(positive regulation of succinate dehydrogenase activity)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:1EKG|rcsb pdb:1LY7|rcsb pdb:3S4M|rcsb pdb:3S5D|rcsb pdb:3S5E|rcsb pdb:3S5F|rcsb pdb:3T3J|rcsb pdb:3T3K|rcsb pdb:3T3L|rcsb pdb:3T3T|rcsb pdb:3T3X|rcsb pdb:5KZ5|rcsb pdb:6NZU|reactome:R-HSA-1268020|reactome:R-HSA-1362409|refseq:NP_000135.2|refseq:NP_001155178.1|refseq:NP_852090.1	-	-	-	figure legend:Fig. 6|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	rogid:enHzDdgfTff5Y6To5z6k+6rpRMk9606	intact-crc:1BFFCD6CB29E107C|rigid:vn9cQdZaW1uhs0hOHQPy5zcjc9A	false	glutathione s tranferase tag:n-n|sufficient binding region:33-493(IPR003953)	sufficient binding region:42-210|ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q16595	uniprotkb:P21912	intact:EBI-949340|ensembl:ENSP00000419243|uniprotkb:O15545|uniprotkb:O95656|uniprotkb:Q15294|uniprotkb:Q5VZ01|uniprotkb:A8MXJ6|uniprotkb:C9JJ89	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:frda_human(display_long)|uniprotkb:Friedreich ataxia protein(gene name synonym)|uniprotkb:FXN(gene name)|psi-mi:FXN(display_short)|uniprotkb:FRDA(gene name synonym)|uniprotkb:X25(gene name synonym)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Gonzalez-Cabo et al. (2005)	pubmed:15961414|imex:IM-17231	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953261|imex:IM-17231-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165060(gene)|ensembl:ENST00000484259(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010039"(response to iron ion)|go:"GO:0010722"(regulation of ferrochelatase activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0019230"(proprioception)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0051349"(positive regulation of lyase activity)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:1904231"(positive regulation of succinate dehydrogenase activity)|go:"GO:1904234"(positive regulation of aconitate hydratase activity)|go:"GO:1990221"(L-cysteine desulfurase complex)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:1EKG|rcsb pdb:1LY7|rcsb pdb:3S4M|rcsb pdb:3S5D|rcsb pdb:3S5E|rcsb pdb:3S5F|rcsb pdb:3T3J|rcsb pdb:3T3K|rcsb pdb:3T3L|rcsb pdb:3T3T|rcsb pdb:3T3X|rcsb pdb:5KZ5|rcsb pdb:6NZU|reactome:R-HSA-1268020|reactome:R-HSA-1362409|refseq:NP_000135.2|refseq:NP_001155178.1|refseq:NP_852090.1	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:enHzDdgfTff5Y6To5z6k+6rpRMk9606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	intact-crc:23B3D78EB906D14E|rigid:LIrvplhsg2jZS0jVe4aVB0DWjJM	false	ha tag:n-n|sufficient binding region:42-210	sufficient binding region:47-280|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)