#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P17706	uniprotkb:P56199	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|ensembl:ENSP00000311857|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955	intact:EBI-2554465|uniprotkb:B2RNU0|ensembl:ENSP00000282588	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:ita1_human(display_long)|uniprotkb:ITGA1(gene name)|psi-mi:ITGA1(display_short)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Mattila et al. (2005)	pubmed:15592458|mint:MINT-8284715|doi:10.1038/ncb1209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7419794|mint:MINT-8284727	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175354(gene)|ensembl:ENST00000309660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902206"(negative regulation of interleukin-2-mediated signaling pathway)|go:"GO:1902215"(negative regulation of interleukin-4-mediated signaling pathway)|go:"GO:1902227"(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1902233"(negative regulation of positive thymic T cell selection)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P17706|rcsb pdb:1L8K|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-6807004|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1|mint:MINT-8284730(identity)	refseq:NP_852478.1|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042311"(vasodilation)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045123"(cellular extravasation)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P56199|rcsb pdb:1PT6|rcsb pdb:1QC5|rcsb pdb:1QCY|rcsb pdb:2L8S|rcsb pdb:2M32|rcsb pdb:4A0Q|rcsb pdb:5HGJ|reactome:R-HSA-216083|reactome:R-HSA-3000157|go:"GO:0034665"(integrin alpha1-beta1 complex)|reactome:R-HSA-416700|reactome:R-HSA-445355|reactome:R-HSA-447041|reactome:R-HSA-75892|ensembl:ENSG00000213949(gene)|ensembl:ENST00000282588(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|dip:DIP-206N|mint:MINT-8284729(identity)	go:"GO:0005886"(plasma membrane)	-	-	figure legend:f1a|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:rapid curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/10/27	2014/10/16	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rogid:rI8GnpuQlkN7TAnJ2eLpECEZOxs9606	intact-crc:3D1E93B3A2D8F580|rigid:nFSylr51TuZDd2W7N9fMl2e7tSU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P17706	uniprotkb:P56199	intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|ensembl:ENSP00000311857|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955	intact:EBI-2554465|uniprotkb:B2RNU0|ensembl:ENSP00000282588	psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym)	psi-mi:ita1_human(display_long)|uniprotkb:ITGA1(gene name)|psi-mi:ITGA1(display_short)|uniprotkb:Laminin and collagen receptor(gene name synonym)|uniprotkb:VLA-1(gene name synonym)|uniprotkb:CD49 antigen-like family member A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mattila et al. (2005)	pubmed:15592458|mint:MINT-8284715|doi:10.1038/ncb1209	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7419815|mint:MINT-8284737	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000175354(gene)|ensembl:ENST00000309660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902206"(negative regulation of interleukin-2-mediated signaling pathway)|go:"GO:1902215"(negative regulation of interleukin-4-mediated signaling pathway)|go:"GO:1902227"(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1902233"(negative regulation of positive thymic T cell selection)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P17706|rcsb pdb:1L8K|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-6807004|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1|mint:MINT-8284742(identity)	refseq:NP_852478.1|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042311"(vasodilation)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045123"(cellular extravasation)|go:"GO:0045178"(basal part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|mint:P56199|rcsb pdb:1PT6|rcsb pdb:1QC5|rcsb pdb:1QCY|rcsb pdb:2L8S|rcsb pdb:2M32|rcsb pdb:4A0Q|rcsb pdb:5HGJ|reactome:R-HSA-216083|reactome:R-HSA-3000157|go:"GO:0034665"(integrin alpha1-beta1 complex)|reactome:R-HSA-416700|reactome:R-HSA-445355|reactome:R-HSA-447041|reactome:R-HSA-75892|ensembl:ENSG00000213949(gene)|ensembl:ENST00000282588(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008305"(integrin complex)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|dip:DIP-206N|mint:MINT-8284740(identity)	-	-	-	figure legend:f1c f1d|comment:homomint|comment:mint|partial coverage:partial coverage|curation depth:rapid curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/10/27	2014/10/16	rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606	rogid:rI8GnpuQlkN7TAnJ2eLpECEZOxs9606	intact-crc:4FDC710C25E09FAC|rigid:nFSylr51TuZDd2W7N9fMl2e7tSU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)