#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:B2GV87 uniprotkb:K7GPR7 intact:EBI-7367607|intact:UNK-5464807|uniprotkb:Q63476|uniprotkb:Q63477|ensembl:ENSRNOP00000021359 intact:EBI-20829049|ensembl:ENSSSCP00000029882 psi-mi:ptpre_rat(display_long)|uniprotkb:Ptpre(gene name)|psi-mi:Ptpre(display_short)|uniprotkb:Ptpe(gene name synonym) psi-mi:k7gpr7_pig(display_long)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nakagawa et al. (2004) pubmed:15522235|mint:MINT-8217326|doi:10.1016/j.bbrc.2004.10.029|imex:IM-26654 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7367681|mint:MINT-8217542|imex:IM-26654-1 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_008758193.1|refseq:XP_008758194.1|rgd:620771|refseq:NP_446219.1|refseq:XP_006230511.1|ensembl:ENSRNOG00000015717(gene)|ensembl:ENSRNOT00000021359(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR029021|mint:MINT-8217544(identity) reactome:R-SSC-5607764|reactome:R-SSC-5663220|reactome:R-SSC-5674135|reactome:R-SSC-6811558|reactome:R-SSC-8853659|reactome:R-SSC-8934903|reactome:R-SSC-8941858|ensembl:ENSSSCG00000007334(gene)|ensembl:ENSSSCT00000033033(transcript)|go:"GO:0002102"(podosome)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045453"(bone resorption)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071253"(connexin binding)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|reactome:R-SSC-1227986|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|reactome:R-SSC-1251985|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|reactome:R-SSC-1253288|reactome:R-SSC-1257604|reactome:R-SSC-1433557|reactome:R-SSC-1433559|reactome:R-SSC-177929|reactome:R-SSC-180292|reactome:R-SSC-186763|reactome:R-SSC-191650|reactome:R-SSC-210990|reactome:R-SSC-354192|reactome:R-SSC-389356|reactome:R-SSC-389513|reactome:R-SSC-3928662|reactome:R-SSC-3928663|reactome:R-SSC-3928664|reactome:R-SSC-3928665|reactome:R-SSC-418592|reactome:R-SSC-418594|reactome:R-SSC-430116|reactome:R-SSC-4420097|reactome:R-SSC-456926|refseq:XP_005672979.1|refseq:XP_005672980.1|mint:MINT-8217546(identity) - comment:"fragmentation type: fragment"|comment:mint comment:"Resulting Phenotypic qualities (properties)[PATO]: PATO:0002221 (increased phosphorylation)" figure legend:f4c|full coverage:Only protein-protein interactions|partial coverage:partial coverage|curation depth:imex curation taxid:9823(pig-endothelium)|taxid:9823(Pig endothelium) - 2011/10/19 2018/11/14 rogid:hBSqv5hv3259RQiN8pFjiBqijdc10116 rogid:nszFhHol9iG9EXI8u6d+wPyzKYw9823 intact-crc:19A66C13E33337E6|rigid:fPqbAFsKPG4BEcS1M/jctDYh83s false trapping mutant:302-302(MINT-8217553)|ha tag:?-? phosphorylated residue:530-530(MINT-8217547) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)