#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0ABM1	uniprotkb:P0ABM5	intact:EBI-2123469|uniprotkb:P33929|uniprotkb:Q2MAP4|ensemblbacteria:AAC75259|ensemblbacteria:BAE76662	intact:EBI-3894922|uniprotkb:P36770|uniprotkb:Q2MAP5|ensemblbacteria:AAC75258|ensemblbacteria:BAE76661	psi-mi:ccmc_ecoli(display_long)|uniprotkb:ccmC(gene name)|psi-mi:ccmC(display_short)|uniprotkb:yejT(gene name synonym)|uniprotkb:yejU(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmC(gene name synonym)|uniprotkb:b2199(locus name)|uniprotkb:JW2187(locus name)	psi-mi:ccmd_ecoli(display_long)|uniprotkb:ccmD(gene name)|psi-mi:ccmD(display_short)|uniprotkb:yojM(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmD(gene name synonym)|uniprotkb:b2198(locus name)|uniprotkb:JW2186(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ahuja et al. (2005)	pubmed:15513913|imex:IM-17163	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3894918|imex:IM-17163-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295447.1|refseq:NP_416703.1|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003557(Cytochrome c-type biogenesis protein CcmC)|ensemblbacteria:AAC75259(transcript)|ensemblbacteria:b2199(gene)|ensemblbacteria:BAE76662(gene)|ensemblbacteria:BAE76662(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0020037"(heme binding)	refseq:WP_000186540.1|refseq:NP_416702.1|interpro:IPR007078("Haem exporter protein D (CcmD)")|ensemblbacteria:AAC75258(transcript)|ensemblbacteria:b2198(gene)|ensemblbacteria:BAE76661(gene)|ensemblbacteria:BAE76661(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)	-	-	-	figure legend:Fig 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2011/05/09	2014/10/16	rogid:0ibTZO7/qV52xbtiWcE7oXm5drc83333	rogid:rEKp7vmIByTqwbRzXQStC5i6qvQ83333	intact-crc:FC3E8A8C252F64E6|rigid:9XjJiAaoGjeazYJklR0liYZCdaw	false	his tag:c-c	strep ii tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P0ABM1	uniprotkb:P0ABM5	intact:EBI-2123469|uniprotkb:P33929|uniprotkb:Q2MAP4|ensemblbacteria:AAC75259|ensemblbacteria:BAE76662	intact:EBI-3894922|uniprotkb:P36770|uniprotkb:Q2MAP5|ensemblbacteria:AAC75258|ensemblbacteria:BAE76661	psi-mi:ccmc_ecoli(display_long)|uniprotkb:ccmC(gene name)|psi-mi:ccmC(display_short)|uniprotkb:yejT(gene name synonym)|uniprotkb:yejU(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmC(gene name synonym)|uniprotkb:b2199(locus name)|uniprotkb:JW2187(locus name)	psi-mi:ccmd_ecoli(display_long)|uniprotkb:ccmD(gene name)|psi-mi:ccmD(display_short)|uniprotkb:yojM(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmD(gene name synonym)|uniprotkb:b2198(locus name)|uniprotkb:JW2186(locus name)	psi-mi:"MI:0096"(pull down)	Ahuja et al. (2005)	pubmed:15513913|imex:IM-17163	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3894959|imex:IM-17163-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295447.1|refseq:NP_416703.1|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003557(Cytochrome c-type biogenesis protein CcmC)|ensemblbacteria:AAC75259(transcript)|ensemblbacteria:b2199(gene)|ensemblbacteria:BAE76662(gene)|ensemblbacteria:BAE76662(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0020037"(heme binding)	refseq:WP_000186540.1|refseq:NP_416702.1|interpro:IPR007078("Haem exporter protein D (CcmD)")|ensemblbacteria:AAC75258(transcript)|ensemblbacteria:b2198(gene)|ensemblbacteria:BAE76661(gene)|ensemblbacteria:BAE76661(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)	-	-	-	figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2011/05/09	2014/10/16	rogid:0ibTZO7/qV52xbtiWcE7oXm5drc83333	rogid:rEKp7vmIByTqwbRzXQStC5i6qvQ83333	intact-crc:F98686C245D16D97|rigid:9XjJiAaoGjeazYJklR0liYZCdaw	false	his tag:c-c	strep ii tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P0ABM1	uniprotkb:P69490	intact:EBI-2123469|uniprotkb:P33929|uniprotkb:Q2MAP4|ensemblbacteria:AAC75259|ensemblbacteria:BAE76662	intact:EBI-1128007|uniprotkb:P33928|uniprotkb:Q2MAP6|ensemblbacteria:AAC75257|ensemblbacteria:BAE76660	psi-mi:ccmc_ecoli(display_long)|uniprotkb:ccmC(gene name)|psi-mi:ccmC(display_short)|uniprotkb:yejT(gene name synonym)|uniprotkb:yejU(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmC(gene name synonym)|uniprotkb:b2199(locus name)|uniprotkb:JW2187(locus name)	psi-mi:ccme_ecoli(display_long)|uniprotkb:ccmE(gene name)|psi-mi:ccmE(display_short)|uniprotkb:b2197(locus name)|uniprotkb:JW2185(locus name)|uniprotkb:yejS(gene name synonym)|uniprotkb:Cytochrome c maturation protein E(gene name synonym)|uniprotkb:Heme chaperone CcmE(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ahuja et al. (2005)	pubmed:15513913|imex:IM-17163	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3894978|imex:IM-17163-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295447.1|refseq:NP_416703.1|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003557(Cytochrome c-type biogenesis protein CcmC)|ensemblbacteria:AAC75259(transcript)|ensemblbacteria:b2199(gene)|ensemblbacteria:BAE76662(gene)|ensemblbacteria:BAE76662(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0020037"(heme binding)	refseq:NP_416701.1|refseq:WP_001026418.1|ensemblbacteria:AAC75257(transcript)|ensemblbacteria:b2197(gene)|ensemblbacteria:BAE76660(gene)|ensemblbacteria:BAE76660(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004329(CcmE/CycJ protein)|interpro:IPR036127|rcsb pdb:1SR3|dip:DIP-9255N	-	-	-	figure legend:Fig 5|comment:"CcmE co-eluted with CcmC only in the presence of CcmD (Fig. 5A), but not in its absence."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2011/05/09	2014/10/16	rogid:0ibTZO7/qV52xbtiWcE7oXm5drc83333	rogid:VWG+HZkkWjdNJy7D6G46VLlR9dc83333	intact-crc:9366A8AB6079F0B9|rigid:xkHQqaEx1afgx30DEPsZmMnS2rc	false	his tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0ABM1	uniprotkb:P0ABM5	intact:EBI-2123469|uniprotkb:P33929|uniprotkb:Q2MAP4|ensemblbacteria:AAC75259|ensemblbacteria:BAE76662	intact:EBI-3894922|uniprotkb:P36770|uniprotkb:Q2MAP5|ensemblbacteria:AAC75258|ensemblbacteria:BAE76661	psi-mi:ccmc_ecoli(display_long)|uniprotkb:ccmC(gene name)|psi-mi:ccmC(display_short)|uniprotkb:yejT(gene name synonym)|uniprotkb:yejU(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmC(gene name synonym)|uniprotkb:b2199(locus name)|uniprotkb:JW2187(locus name)	psi-mi:ccmd_ecoli(display_long)|uniprotkb:ccmD(gene name)|psi-mi:ccmD(display_short)|uniprotkb:yojM(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmD(gene name synonym)|uniprotkb:b2198(locus name)|uniprotkb:JW2186(locus name)	psi-mi:"MI:0096"(pull down)	Ahuja et al. (2005)	pubmed:15513913|imex:IM-17163	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3894978|imex:IM-17163-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001295447.1|refseq:NP_416703.1|interpro:IPR002541(Cytochrome c assembly protein)|interpro:IPR003557(Cytochrome c-type biogenesis protein CcmC)|ensemblbacteria:AAC75259(transcript)|ensemblbacteria:b2199(gene)|ensemblbacteria:BAE76662(gene)|ensemblbacteria:BAE76662(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0020037"(heme binding)	refseq:WP_000186540.1|refseq:NP_416702.1|interpro:IPR007078("Haem exporter protein D (CcmD)")|ensemblbacteria:AAC75258(transcript)|ensemblbacteria:b2198(gene)|ensemblbacteria:BAE76661(gene)|ensemblbacteria:BAE76661(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)	-	-	-	figure legend:Fig 5|comment:"CcmE co-eluted with CcmC only in the presence of CcmD (Fig. 5A), but not in its absence."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2011/05/09	2014/10/16	rogid:0ibTZO7/qV52xbtiWcE7oXm5drc83333	rogid:rEKp7vmIByTqwbRzXQStC5i6qvQ83333	intact-crc:9366A8AB6079F0B9|rigid:xkHQqaEx1afgx30DEPsZmMnS2rc	false	his tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P0ABM5	uniprotkb:P69490	intact:EBI-3894922|uniprotkb:P36770|uniprotkb:Q2MAP5|ensemblbacteria:AAC75258|ensemblbacteria:BAE76661	intact:EBI-1128007|uniprotkb:P33928|uniprotkb:Q2MAP6|ensemblbacteria:AAC75257|ensemblbacteria:BAE76660	psi-mi:ccmd_ecoli(display_long)|uniprotkb:ccmD(gene name)|psi-mi:ccmD(display_short)|uniprotkb:yojM(gene name synonym)|uniprotkb:Cytochrome c-type biogenesis protein CcmD(gene name synonym)|uniprotkb:b2198(locus name)|uniprotkb:JW2186(locus name)	psi-mi:ccme_ecoli(display_long)|uniprotkb:ccmE(gene name)|psi-mi:ccmE(display_short)|uniprotkb:b2197(locus name)|uniprotkb:JW2185(locus name)|uniprotkb:yejS(gene name synonym)|uniprotkb:Cytochrome c maturation protein E(gene name synonym)|uniprotkb:Heme chaperone CcmE(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ahuja et al. (2005)	pubmed:15513913|imex:IM-17163	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3894939|imex:IM-17163-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_000186540.1|refseq:NP_416702.1|interpro:IPR007078("Haem exporter protein D (CcmD)")|ensemblbacteria:AAC75258(transcript)|ensemblbacteria:b2198(gene)|ensemblbacteria:BAE76661(gene)|ensemblbacteria:BAE76661(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017004"(cytochrome complex assembly)|go:"GO:0031235"(intrinsic component of the cytoplasmic side of the plasma membrane)	refseq:NP_416701.1|refseq:WP_001026418.1|ensemblbacteria:AAC75257(transcript)|ensemblbacteria:b2197(gene)|ensemblbacteria:BAE76660(gene)|ensemblbacteria:BAE76660(transcript)|go:"GO:0015886"(heme transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0031237"(intrinsic component of periplasmic side of plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR004329(CcmE/CycJ protein)|interpro:IPR036127|rcsb pdb:1SR3|dip:DIP-9255N	-	-	-	figure legend:Fig 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2011/05/09	2014/10/16	rogid:rEKp7vmIByTqwbRzXQStC5i6qvQ83333	rogid:VWG+HZkkWjdNJy7D6G46VLlR9dc83333	intact-crc:10DFD7B9CFD21A83|rigid:I3e+bjBcb/pDm0Me334lR6BO0JE	false	strep ii tag:c-c	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)