#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6Y5D8 uniprotkb:Q29502-PRO_0000304927 intact:EBI-4396535|uniprotkb:Q6Y5D6|uniprotkb:Q6Y5D7|uniprotkb:Q99MT3|uniprotkb:Q99MT4|ensembl:ENSMUSP00000075658 intact:EBI-4406512 psi-mi:rhg10_mouse(display_long)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym) psi-mi:q29502-pro_0000304927(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Koeppel et al. (2004) pubmed:15471851|imex:IM-16837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4396533|imex:IM-16837-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084389.2|refseq:XP_017168506.1|refseq:XP_006531558.1|refseq:XP_006531561.1|refseq:XP_006531563.1|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149 intact:EBI-4396569(chain-parent) - - chain-seq-start:213|chain-seq-end:524 figure legend:text|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/09/02 2014/10/16 rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090 rogid:0EdPVvCwjwCY1RSxeBWPztPOgrg9986 intact-crc:55BAEA4532B042F8|rigid:ejkVT6U+3R846sdEmhzGnpWZJjM false sufficient binding region:665-786 mutation:278-278 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q6Y5D8 uniprotkb:Q29502-PRO_0000304927 intact:EBI-4396535|uniprotkb:Q6Y5D6|uniprotkb:Q6Y5D7|uniprotkb:Q99MT3|uniprotkb:Q99MT4|ensembl:ENSMUSP00000075658 intact:EBI-4406512 psi-mi:rhg10_mouse(display_long)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym) psi-mi:q29502-pro_0000304927(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Koeppel et al. (2004) pubmed:15471851|imex:IM-16837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4396610|imex:IM-16837-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084389.2|refseq:XP_017168506.1|refseq:XP_006531558.1|refseq:XP_006531561.1|refseq:XP_006531563.1|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149 intact:EBI-4396569(chain-parent) - - chain-seq-start:213|chain-seq-end:524 figure legend:1a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/09/02 2014/10/16 rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090 rogid:0EdPVvCwjwCY1RSxeBWPztPOgrg9986 intact-crc:33383A38192F9D7F|rigid:ejkVT6U+3R846sdEmhzGnpWZJjM false sufficient binding region:665-786 mutation:278-278 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q29502-PRO_0000304927 uniprotkb:Q6Y5D8 intact:EBI-4406512 intact:EBI-4396535|uniprotkb:Q6Y5D6|uniprotkb:Q6Y5D7|uniprotkb:Q99MT3|uniprotkb:Q99MT4|ensembl:ENSMUSP00000075658 psi-mi:q29502-pro_0000304927(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym) psi-mi:rhg10_mouse(display_long)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym) psi-mi:"MI:0096"(pull down) Koeppel et al. (2004) pubmed:15471851|imex:IM-16837 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-4396634|imex:IM-16837-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4396569(chain-parent) refseq:NP_084389.2|refseq:XP_017168506.1|refseq:XP_006531558.1|refseq:XP_006531561.1|refseq:XP_006531563.1|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027267|interpro:IPR035485|interpro:IPR035486|interpro:IPR036028|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149 - chain-seq-start:213|chain-seq-end:524 - figure legend:1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/09/02 2014/10/16 rogid:0EdPVvCwjwCY1RSxeBWPztPOgrg9986 rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090 intact-crc:2618313A76648EFD|rigid:ejkVT6U+3R846sdEmhzGnpWZJjM false mutation:278-278|glutathione s tranferase tag:n-n sufficient binding region:665-786|35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q6Y5D8-1 uniprotkb:Q29502-PRO_0000304927 intact:EBI-4396677|ensembl:ENSMUSP00000075658 intact:EBI-4406512 psi-mi:q6y5d8-1(display_long)|uniprotkb:PS-GAP-a(isoform synonym)|uniprotkb:PSGAP-m(isoform synonym)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym) psi-mi:q29502-pro_0000304927(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Koeppel et al. (2004) pubmed:15471851|imex:IM-16837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4406661|imex:IM-16837-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4396535(isoform-parent)|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript) intact:EBI-4396569(chain-parent) - - chain-seq-start:213|chain-seq-end:524 figure legend:5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/09/02 2014/10/16 rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090 rogid:0EdPVvCwjwCY1RSxeBWPztPOgrg9986 intact-crc:E566E577F3B01992|rigid:ejkVT6U+3R846sdEmhzGnpWZJjM false myc tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6Y5D8-1 uniprotkb:Q29502-PRO_0000304927 intact:EBI-4396677|ensembl:ENSMUSP00000075658 intact:EBI-4406512 psi-mi:q6y5d8-1(display_long)|uniprotkb:PS-GAP-a(isoform synonym)|uniprotkb:PSGAP-m(isoform synonym)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym) psi-mi:q29502-pro_0000304927(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Koeppel et al. (2004) pubmed:15471851|imex:IM-16837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4406649|imex:IM-16837-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4396535(isoform-parent)|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript) intact:EBI-4396569(chain-parent) - - chain-seq-start:213|chain-seq-end:524 figure legend:5b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/09/02 2014/10/16 rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090 rogid:0EdPVvCwjwCY1RSxeBWPztPOgrg9986 intact-crc:A4823235476F6E11|rigid:ejkVT6U+3R846sdEmhzGnpWZJjM false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6Y5D8-1 uniprotkb:Q29502-PRO_0000304927 intact:EBI-4396677|ensembl:ENSMUSP00000075658 intact:EBI-4406512 psi-mi:q6y5d8-1(display_long)|uniprotkb:PS-GAP-a(isoform synonym)|uniprotkb:PSGAP-m(isoform synonym)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym) psi-mi:q29502-pro_0000304927(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Koeppel et al. (2004) pubmed:15471851|imex:IM-16837 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-4406572|imex:IM-16837-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4396535(isoform-parent)|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript) intact:EBI-4396569(chain-parent) - - chain-seq-start:213|chain-seq-end:524 figure legend:5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/09/02 2014/10/16 rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090 rogid:0EdPVvCwjwCY1RSxeBWPztPOgrg9986 intact-crc:6322455C18B574AA|rigid:ejkVT6U+3R846sdEmhzGnpWZJjM false ha tag:?-? flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q29502-PRO_0000304927 uniprotkb:Q6Y5D8-1 intact:EBI-4406512 intact:EBI-4396677|ensembl:ENSMUSP00000075658 psi-mi:q29502-pro_0000304927(display_long)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:p21-activated protein kinase I(gene name synonym) psi-mi:q6y5d8-1(display_long)|uniprotkb:PS-GAP-a(isoform synonym)|uniprotkb:PSGAP-m(isoform synonym)|uniprotkb:Arhgap10(gene name)|psi-mi:Arhgap10(display_short)|uniprotkb:PH and SH3 domain-containing rhoGAP protein(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 10(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Koeppel et al. (2004) pubmed:15471851|imex:IM-16837 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-4396745|imex:IM-16837-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-4396569(chain-parent) intact:EBI-4396535(isoform-parent)|ensembl:ENSMUSG00000037148(gene)|ensembl:ENSMUST00000076316(transcript) go:"GO:0048471"(perinuclear region of cytoplasm) chain-seq-start:213|chain-seq-end:524 - figure legend:8b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2011/09/02 2014/10/16 rogid:0EdPVvCwjwCY1RSxeBWPztPOgrg9986 rogid:BkjrZ57wZtUokXauJ8vc/VDbMTU10090 intact-crc:36CDC33110CFD10B|rigid:ejkVT6U+3R846sdEmhzGnpWZJjM false green fluorescent protein tag:?-? ha tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)