#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q02199	uniprotkb:Q00416	intact:EBI-12315|ensemblfungi:YGL172W|uniprotkb:D6VTY0	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:nup49_yeast(display_long)|uniprotkb:NUP49(gene name)|psi-mi:NUP49(display_short)|uniprotkb:NSP49(gene name synonym)|uniprotkb:YGL172W(locus name)|uniprotkb:G1648(orf name)|uniprotkb:Nuclear pore protein NUP49/NSP49(gene name synonym)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5235312|imex:IM-17296-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011343.1|sgd:S000003140|ensemblfungi:YGL172W(gene)|ensemblfungi:YGL172W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036228"(protein localization to nuclear inner membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044613"(nuclear pore central transport channel)|interpro:IPR024864|interpro:IPR025574|interpro:IPR039079|mint:Q02199|dip:DIP-709N	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	-	crc64:88F0FF95B3A8BD89	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:2x0Rt5ViHxBEKxPzOcfnyOdgmpg559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:B4D2A84A00F6C363|rigid:MTciFse+nThk6D/FI1I/o+1vYLM	false	sufficient binding region:21-472	sufficient binding region:1-975	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04050	uniprotkb:Q00416	intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5235296|imex:IM-17296-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	crc64:A45C1360FF99F968	crc64:88F0FF95B3A8BD89	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:565E0A6517D7F43D|rigid:DdnrqjoYYWccGpH8oWAVgJiBIkc	false	sufficient binding region:1497-1733	sufficient binding region:1-975	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00416	uniprotkb:Q06523	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	intact:EBI-33312|uniprotkb:D6W4E5|ensemblfungi:YPR148C	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:yp148_yeast(display_long)|uniprotkb:YPR148C(locus name)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953193|imex:IM-17296-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	refseq:NP_015474.1|sgd:S000006352|dip:DIP-3808N|ensemblfungi:YPR148C(gene)|ensemblfungi:YPR148C_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR018859|interpro:IPR027267	-	crc64:88F0FF95B3A8BD89	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	rogid:OvYsZcwg3M59zGlWX9ZCOZg/TuI559292	intact-crc:026D9050D079A092|rigid:R1nGNabCEEv5e+biKfb/mlnXDs8	false	sufficient binding region:1-975	sufficient binding region:95-435	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07276	uniprotkb:Q00416	intact:EBI-14757|uniprotkb:E9P8X9|uniprotkb:D6VV38|ensemblfungi:YGR258C	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:rad2_yeast(display_long)|uniprotkb:YGR258C(locus name)|uniprotkb:RAD2(gene name)|psi-mi:RAD2(display_short)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5235287|imex:IM-17296-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011774.1|sgd:S000003490|ensemblfungi:YGR258C(gene)|ensemblfungi:YGR258C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001044(Xeroderma pigmentosum group G protein)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR036279|rcsb pdb:2LOX|rcsb pdb:4Q0R|rcsb pdb:4Q0W|rcsb pdb:4Q0Z|rcsb pdb:4Q10|dip:DIP-5869N	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	crc64:682D4AECFBD7F0F3	crc64:88F0FF95B3A8BD89	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:AjfoZICG5nB2MP8AoPnDGRGijKE559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:7F053D2B1D538605|rigid:W0Iwm/v/lpMVaHueZXdJLhQH2/s	false	sufficient binding region:491-544	sufficient binding region:1-975	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q00416	uniprotkb:P38689	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	intact:EBI-9877|uniprotkb:D3DKQ2|ensemblfungi:YHL011C	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:kpr3_yeast(display_long)|uniprotkb:PRS3(gene name)|psi-mi:PRS3(display_short)|uniprotkb:Phosphoribosyl pyrophosphate synthase 3(gene name synonym)|uniprotkb:PRPS3(gene name synonym)|uniprotkb:YHL011C(locus name)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5235271|imex:IM-17296-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	refseq:NP_011852.1|sgd:S000001003|ensemblfungi:YHL011C(gene)|ensemblfungi:YHL011C_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0031505"(fungal-type cell wall organization)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|reactome:R-SCE-73843|dip:DIP-4307N|mint:P38689	-	crc64:88F0FF95B3A8BD89	crc64:D4839D217B7513C4	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	rogid:8Km+h9PM9lJSTwLUTObbTkNkKig559292	intact-crc:B0FEDA36AE1EF5DD|rigid:7p4pbrMWQGYU+h3PvjQL7JDxDjk	false	sufficient binding region:1-975	sufficient binding region:142-204	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32327	uniprotkb:Q00416	intact:EBI-14365|uniprotkb:D6VQL4|ensemblfungi:YBR218C	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:pyc2_yeast(display_long)|uniprotkb:PYC2(gene name)|psi-mi:PYC2(display_short)|uniprotkb:YBR218C(locus name)|uniprotkb:YBR1507(orf name)|uniprotkb:Pyruvic carboxylase 2(gene name synonym)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5235304|imex:IM-17296-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009777.1|sgd:S000000422|ensemblfungi:YBR218C(gene)|ensemblfungi:YBR218C_mRNA(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0009374"(biotin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|mint:P32327|dip:DIP-6426N	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	crc64:AD60DA3A60F5E001	crc64:88F0FF95B3A8BD89	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:FvnnWuplwrt91+684m4fpfW2su8559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:C63D985BC7DE1DA8|rigid:4Ur66o+gwdqbO7i8RBRNcwo98Co	false	sufficient binding region:696-979	sufficient binding region:1-975	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q01722	uniprotkb:Q00416	intact:EBI-7469|uniprotkb:D6W0Y9|ensemblfungi:YNL199C	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:gcr2_yeast(display_long)|uniprotkb:N1374(orf name)|uniprotkb:YNL199C(locus name)|uniprotkb:GCR2(gene name)|psi-mi:GCR2(display_short)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-5235279|imex:IM-17296-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005143|refseq:NP_014200.1|mint:Q01722|dip:DIP-732N|ensemblfungi:YNL199C(gene)|ensemblfungi:YNL199C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060196"(positive regulation of antisense RNA transcription)|go:"GO:0060963"(positive regulation of ribosomal protein gene transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	crc64:958D4A9393255B1B	crc64:88F0FF95B3A8BD89	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:k2bS3C3eQe+q4RlZdBIgx69PVME559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:4E68A5550F0F0C69|rigid:yPmwLXfHQqQ3cfb2svuNcLhPXDI	false	sufficient binding region:163-534	sufficient binding region:1-975	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04050	uniprotkb:Q00416	intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953502|imex:IM-17296-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	crc64:A45C1360FF99F968	crc64:88F0FF95B3A8BD89	figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:ADA9F53153ED5D47|rigid:DdnrqjoYYWccGpH8oWAVgJiBIkc	false	sufficient binding region:1497-1733	sufficient binding region:1-565	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00416	uniprotkb:P07276	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	intact:EBI-14757|uniprotkb:E9P8X9|uniprotkb:D6VV38|ensemblfungi:YGR258C	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:rad2_yeast(display_long)|uniprotkb:YGR258C(locus name)|uniprotkb:RAD2(gene name)|psi-mi:RAD2(display_short)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953510|imex:IM-17296-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	refseq:NP_011774.1|sgd:S000003490|ensemblfungi:YGR258C(gene)|ensemblfungi:YGR258C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001044(Xeroderma pigmentosum group G protein)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR036279|rcsb pdb:2LOX|rcsb pdb:4Q0R|rcsb pdb:4Q0W|rcsb pdb:4Q0Z|rcsb pdb:4Q10|dip:DIP-5869N	-	crc64:88F0FF95B3A8BD89	crc64:682D4AECFBD7F0F3	figure legend:Figure 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	rogid:AjfoZICG5nB2MP8AoPnDGRGijKE559292	intact-crc:C0E427EEF2C617F3|rigid:W0Iwm/v/lpMVaHueZXdJLhQH2/s	false	sufficient binding region:1-565	sufficient binding region:327-672	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q02555	uniprotkb:Q00416	intact:EBI-15673|uniprotkb:D6W065|uniprotkb:Q04008|uniprotkb:Q05038|ensemblfungi:YMR239C	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:rnt1_yeast(display_long)|uniprotkb:RNT1(gene name)|psi-mi:RNT1(display_short)|uniprotkb:YMR239C(locus name)|uniprotkb:YM9408.01C(orf name)|uniprotkb:YM9959.21(orf name)|uniprotkb:Ribonuclease III(gene name synonym)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953609|imex:IM-17296-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013966.1|sgd:S000004852|ensemblfungi:YMR239C(gene)|ensemblfungi:YMR239C_mRNA(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0034963"(box C/D RNA processing)|go:"GO:0034964"(box H/ACA RNA processing)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|interpro:IPR000999(Ribonuclease III)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR040540|interpro:IPR044449|rcsb pdb:1T4L|rcsb pdb:1T4N|rcsb pdb:1T4O|rcsb pdb:2LUP|rcsb pdb:2LUQ|rcsb pdb:4OOG|rcsb pdb:5T16|rcsb pdb:2LBS|dip:DIP-4298N|mint:Q02555	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	crc64:570294172E66A0DE	crc64:88F0FF95B3A8BD89	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:RskP9pfDLnItA8VCF7KUlaebZEQ559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:D771DC7A897461B2|rigid:HoiQQ5GdxMAKRTPlcFUTkwzqPvk	false	sufficient binding region:1-191	sufficient binding region:1-565,549-1153	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00416	uniprotkb:P07276	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	intact:EBI-14757|uniprotkb:E9P8X9|uniprotkb:D6VV38|ensemblfungi:YGR258C	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:rad2_yeast(display_long)|uniprotkb:YGR258C(locus name)|uniprotkb:RAD2(gene name)|psi-mi:RAD2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953592|imex:IM-17296-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	refseq:NP_011774.1|sgd:S000003490|ensemblfungi:YGR258C(gene)|ensemblfungi:YGR258C_mRNA(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001044(Xeroderma pigmentosum group G protein)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR036279|rcsb pdb:2LOX|rcsb pdb:4Q0R|rcsb pdb:4Q0W|rcsb pdb:4Q0Z|rcsb pdb:4Q10|dip:DIP-5869N	-	crc64:88F0FF95B3A8BD89	crc64:682D4AECFBD7F0F3	figure legend:Figure 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	rogid:AjfoZICG5nB2MP8AoPnDGRGijKE559292	intact-crc:8891041EE5D6F975|rigid:W0Iwm/v/lpMVaHueZXdJLhQH2/s	false	myc tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q00416	uniprotkb:Q02555	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	intact:EBI-15673|uniprotkb:D6W065|uniprotkb:Q04008|uniprotkb:Q05038|ensemblfungi:YMR239C	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:rnt1_yeast(display_long)|uniprotkb:RNT1(gene name)|psi-mi:RNT1(display_short)|uniprotkb:YMR239C(locus name)|uniprotkb:YM9408.01C(orf name)|uniprotkb:YM9959.21(orf name)|uniprotkb:Ribonuclease III(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953601|imex:IM-17296-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	refseq:NP_013966.1|sgd:S000004852|ensemblfungi:YMR239C(gene)|ensemblfungi:YMR239C_mRNA(transcript)|go:"GO:0000294"(nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0030847"(termination of RNA polymerase II transcription, exosome-dependent)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0034963"(box C/D RNA processing)|go:"GO:0034964"(box H/ACA RNA processing)|go:"GO:0060237"(regulation of fungal-type cell wall organization)|interpro:IPR000999(Ribonuclease III)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR040540|interpro:IPR044449|rcsb pdb:1T4L|rcsb pdb:1T4N|rcsb pdb:1T4O|rcsb pdb:2LUP|rcsb pdb:2LUQ|rcsb pdb:4OOG|rcsb pdb:5T16|rcsb pdb:2LBS|dip:DIP-4298N|mint:Q02555	-	crc64:88F0FF95B3A8BD89	crc64:570294172E66A0DE	figure legend:Figure 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	rogid:RskP9pfDLnItA8VCF7KUlaebZEQ559292	intact-crc:C7DED372F55FF93E|rigid:HoiQQ5GdxMAKRTPlcFUTkwzqPvk	false	myc tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P04050	uniprotkb:Q00416	intact:EBI-15760|uniprotkb:Q12364|uniprotkb:Q92315|uniprotkb:D6VRK8|intact:EBI-3652496|ensemblfungi:YDL140C	intact:EBI-16945|uniprotkb:Q06448|uniprotkb:D6VZ65|ensemblfungi:YLR430W|uniprotkb:E9P9Z4	psi-mi:rpb1_yeast(display_long)|uniprotkb:RPO21(gene name)|psi-mi:RPO21(display_short)|uniprotkb:RPB220(gene name synonym)|uniprotkb:RPB1(gene name synonym)|uniprotkb:SUA8(gene name synonym)|uniprotkb:YDL140C(locus name)|uniprotkb:D2150(orf name)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase II subunit B220(gene name synonym)	psi-mi:sen1_yeast(display_long)|uniprotkb:SEN1(gene name)|psi-mi:SEN1(display_short)|uniprotkb:YLR430W(locus name)|uniprotkb:L9576.1(orf name)|uniprotkb:tRNA-splicing endonuclease positive effector(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ursic et al. (2004)	pubmed:15121901|imex:IM-17296	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3953587|imex:IM-17296-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010141.1|sgd:S000002299|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:6NPW|rcsb pdb:6O6C|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ2|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0019985"(translesion synthesis)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:1I3Q|rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|rcsb pdb:1WCM|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2E2H|rcsb pdb:2E2I|rcsb pdb:2E2J|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2L0I|rcsb pdb:2LO6|rcsb pdb:2NVQ|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:3GTG|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|ensemblfungi:YDL140C(gene)|ensemblfungi:YDL140C_mRNA(transcript)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4GWQ|rcsb pdb:4V1M|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LVF|rcsb pdb:5M9D|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VKL|rcsb pdb:5VKO|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6GYK|dip:DIP-611N|mint:P04050|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519	refseq:NP_013534.3|ensemblfungi:YLR430W_mRNA(transcript)|go:"GO:0001147"(transcription termination site sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006364"(rRNA processing)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0033678"(5'-3' DNA/RNA helicase activity)|go:"GO:0035649"(Nrd1 complex)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0045005"(DNA-dependent DNA replication maintenance of fidelity)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0060257"(negative regulation of flocculation)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|interpro:IPR024481|interpro:IPR026121|interpro:IPR027417|go:"GO:0032574"(5'-3' RNA helicase activity)|interpro:IPR041677|interpro:IPR041679|interpro:IPR044340|rcsb pdb:5MZN|rcsb pdb:6GC3|rcsb pdb:6I59|rcsb pdb:6O3W|rcsb pdb:6O3X|rcsb pdb:6O3Y|sgd:S000004422|ensemblfungi:YLR430W(gene)|dip:DIP-881N|mint:Q00416	-	crc64:A45C1360FF99F968	crc64:88F0FF95B3A8BD89	figure legend:Figure 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/05/25	2014/10/16	rogid:uDrfU2DMv4cFvCc7WKl65Aq8qOg559292	rogid:37O2NpNKa7l87R1ELXdUZCS4Waw559292	intact-crc:E99E899FD6146B01|rigid:DdnrqjoYYWccGpH8oWAVgJiBIkc	false	ha tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)