#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q6IQX8 uniprotkb:O16844 intact:EBI-3044006|ensembl:ENSMUSP00000068184|ensembl:ENSMUSP00000126854|ensembl:ENSMUSP00000154709|uniprotkb:Q921W9|uniprotkb:Q924S6|uniprotkb:Q9CVF3|intact:EBI-3508329 intact:EBI-102069|intact:EBI-868718|intact:EBI-1151174|intact:EBI-497208|uniprotkb:A1Z6X4|uniprotkb:B5RIP3|uniprotkb:Q6AWI9|uniprotkb:Q8IH04|ensemblmetazoa:FBpp0088087|ensemblmetazoa:FBpp0307854 psi-mi:zn219_mouse(display_long)|uniprotkb:Znf219(gene name)|psi-mi:Znf219(display_short)|uniprotkb:Zfp219(gene name synonym) psi-mi:cos_drome(display_long)|uniprotkb:cos(gene name)|psi-mi:cos(display_short)|uniprotkb:cos2(gene name synonym)|uniprotkb:costal-2(gene name synonym)|uniprotkb:Kinesin-like protein costal2(gene name synonym)|uniprotkb:CG1708(orf name) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510234|imex:IM-16925-50 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000049295(gene)|ensembl:ENSMUST00000067549(transcript)|ensembl:ENSMUST00000166169(transcript)|ensembl:ENSMUST00000226522(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060174"(limb bud formation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6IQX8|refseq:XP_011243478.1|refseq:XP_011243479.1|refseq:XP_017171669.1|refseq:NP_081524.2|refseq:NP_001240623.1|refseq:NP_001240624.1|refseq:XP_006519561.1|refseq:XP_006519562.1|refseq:XP_006519564.1|refseq:XP_006519565.1|refseq:XP_006519566.1|refseq:XP_006519567.1|refseq:XP_006519568.1 refseq:NP_477092.1|flybase:FBgn0000352|ensemblmetazoa:FBgn0000352(gene)|ensemblmetazoa:FBtr0089015(transcript)|ensemblmetazoa:FBtr0336916(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005119"(smoothened binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_001260765.1|dip:DIP-22550N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2018/01/16 rogid:Q6ebFbVDwgd46TS1dBOEk3kNYO410090 rogid:6k5Ur6D1FPXovKN/UUjCoqKajQk7227 intact-crc:01D34D7DE9AF05CD|rigid:gddy/cTvyUUwSMNCV5jEy0uax3c false - sufficient binding region:538-751 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19538 uniprotkb:Q9Z0P7 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508331|imex:IM-16925-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:C4D8A9E6122E3C4E|rigid:MDPnrONhTK7rg59mqbQO9uAgxX8 false - sufficient binding region:326-484 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08151 uniprotkb:Q9Z0P7 intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508557|imex:IM-16925-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:D0B81082E4A34625|rigid:XUAGmorFe/HLmhcLkChTPfme6O8 false - sufficient binding region:13-325 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16110 uniprotkb:Q9Z0P7 intact:EBI-3508325 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508596|imex:IM-16925-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:6749FC129FFAC0F3|rigid:YE6eIYM0G+d7OHDDVnIFScXkeDQ false - sufficient binding region:13-73 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VG38 uniprotkb:P19538 intact:EBI-110605|ensemblmetazoa:FBpp0082134 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:q9vg38_drome(display_long)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:CG6054(orf name)|uniprotkb:Dmel\CG6054(gene name synonym)|uniprotkb:"SU(FU)"(gene name synonym)|uniprotkb:SUFU(gene name synonym)|uniprotkb:"Su(Fu)"(gene name synonym)|uniprotkb:SuFu(gene name synonym)|uniprotkb:Sufu(gene name synonym)|uniprotkb:dSufu(gene name synonym)|uniprotkb:"su(fu)"(gene name synonym)|uniprotkb:sufu(gene name synonym)|uniprotkb:Dmel_CG6054(orf name)|uniprotkb:d Sufu(gene name synonym) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508619|imex:IM-16925-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536750.2|flybase:FBgn0005355|dip:DIP-60773N|ensemblmetazoa:FBgn0005355(gene)|ensemblmetazoa:FBtr0082665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|rcsb pdb:4KMA|rcsb pdb:6LPH|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684 refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:bgRdXcd2LSsl7sfv4ArpqgWFzeU7227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:76DA64DD00E9D396|rigid:+RKQDOLoQHupscqcPxD6ROorEe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O16844 uniprotkb:P23647 intact:EBI-102069|intact:EBI-868718|intact:EBI-1151174|intact:EBI-497208|uniprotkb:A1Z6X4|uniprotkb:B5RIP3|uniprotkb:Q6AWI9|uniprotkb:Q8IH04|ensemblmetazoa:FBpp0088087|ensemblmetazoa:FBpp0307854 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 psi-mi:cos_drome(display_long)|uniprotkb:cos(gene name)|psi-mi:cos(display_short)|uniprotkb:cos2(gene name synonym)|uniprotkb:costal-2(gene name synonym)|uniprotkb:Kinesin-like protein costal2(gene name synonym)|uniprotkb:CG1708(orf name) psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508660|imex:IM-16925-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_477092.1|flybase:FBgn0000352|ensemblmetazoa:FBgn0000352(gene)|ensemblmetazoa:FBtr0089015(transcript)|ensemblmetazoa:FBtr0336916(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005119"(smoothened binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_001260765.1|dip:DIP-22550N ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:6k5Ur6D1FPXovKN/UUjCoqKajQk7227 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 intact-crc:623B81954CF3663F|rigid:bJKZP3SMTzOy8HkKRhCzyMFRo9s false sufficient binding region:538-751 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:O88907 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508753|imex:IM-16925-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:5A50215EC6309BEC|rigid:Zvp4RZwaI5uBDNUQZJpWHiv7S4g false sufficient binding region:13-384 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88907 uniprotkb:O55128 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508797|imex:IM-16925-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:ECEDBCDF0C5DAA4B|rigid:7PJ1xGKirEloUlWymEDycHoHofE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10071 uniprotkb:Q9Z0P7 intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508948|imex:IM-16925-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:41DA065A191C18F6|rigid:G1O+BklRsZn7dr4iaXZ/4v325IA false - sufficient binding region:13-384 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88907 uniprotkb:O16844 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-102069|intact:EBI-868718|intact:EBI-1151174|intact:EBI-497208|uniprotkb:A1Z6X4|uniprotkb:B5RIP3|uniprotkb:Q6AWI9|uniprotkb:Q8IH04|ensemblmetazoa:FBpp0088087|ensemblmetazoa:FBpp0307854 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:cos_drome(display_long)|uniprotkb:cos(gene name)|psi-mi:cos(display_short)|uniprotkb:cos2(gene name synonym)|uniprotkb:costal-2(gene name synonym)|uniprotkb:Kinesin-like protein costal2(gene name synonym)|uniprotkb:CG1708(orf name) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510264|imex:IM-16925-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N refseq:NP_477092.1|flybase:FBgn0000352|ensemblmetazoa:FBgn0000352(gene)|ensemblmetazoa:FBtr0089015(transcript)|ensemblmetazoa:FBtr0336916(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005119"(smoothened binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007476"(imaginal disc-derived wing morphogenesis)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0008017"(microtubule binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0140311"(protein sequestering activity)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_001260765.1|dip:DIP-22550N - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:6k5Ur6D1FPXovKN/UUjCoqKajQk7227 intact-crc:0AC9D339A8CD2464|rigid:0ZhIGct1oPreXtXOGzxVrE3NZrY false - sufficient binding region:538-751 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23647 uniprotkb:O09000 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508675|imex:IM-16925-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:ADE55A123598A06B|rigid:G/7D4eYekuIU8Wri5hq3EY5s6EM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VG38 uniprotkb:P19538 intact:EBI-110605|ensemblmetazoa:FBpp0082134 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:q9vg38_drome(display_long)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:CG6054(orf name)|uniprotkb:Dmel\CG6054(gene name synonym)|uniprotkb:"SU(FU)"(gene name synonym)|uniprotkb:SUFU(gene name synonym)|uniprotkb:"Su(Fu)"(gene name synonym)|uniprotkb:SuFu(gene name synonym)|uniprotkb:Sufu(gene name synonym)|uniprotkb:dSufu(gene name synonym)|uniprotkb:"su(fu)"(gene name synonym)|uniprotkb:sufu(gene name synonym)|uniprotkb:Dmel_CG6054(orf name)|uniprotkb:d Sufu(gene name synonym) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508631|imex:IM-16925-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536750.2|flybase:FBgn0005355|dip:DIP-60773N|ensemblmetazoa:FBgn0005355(gene)|ensemblmetazoa:FBtr0082665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|rcsb pdb:4KMA|rcsb pdb:6LPH|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684 refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:bgRdXcd2LSsl7sfv4ArpqgWFzeU7227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:96D978D5D3DF8F3C|rigid:+RKQDOLoQHupscqcPxD6ROorEe0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23647 uniprotkb:Q9VG38 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 intact:EBI-110605|ensemblmetazoa:FBpp0082134 psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:q9vg38_drome(display_long)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:CG6054(orf name)|uniprotkb:Dmel\CG6054(gene name synonym)|uniprotkb:"SU(FU)"(gene name synonym)|uniprotkb:SUFU(gene name synonym)|uniprotkb:"Su(Fu)"(gene name synonym)|uniprotkb:SuFu(gene name synonym)|uniprotkb:Sufu(gene name synonym)|uniprotkb:dSufu(gene name synonym)|uniprotkb:"su(fu)"(gene name synonym)|uniprotkb:sufu(gene name synonym)|uniprotkb:Dmel_CG6054(orf name)|uniprotkb:d Sufu(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510218|imex:IM-16925-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N refseq:NP_536750.2|flybase:FBgn0005355|dip:DIP-60773N|ensemblmetazoa:FBgn0005355(gene)|ensemblmetazoa:FBtr0082665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|rcsb pdb:4KMA|rcsb pdb:6LPH|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 rogid:bgRdXcd2LSsl7sfv4ArpqgWFzeU7227 intact-crc:21DF64C54405BC7D|rigid:7HVwSLS2cRCRCJPL81JAs0bg3Q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23647 uniprotkb:P19538 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508646|imex:IM-16925-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 intact-crc:8D9A7C35A672410A|rigid:WNQgMeK//ptw2jJWqJcqucWKz7w false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16110 uniprotkb:P16110 intact:EBI-3508325 intact:EBI-3508325 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508669|imex:IM-16925-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 intact-crc:0F05F25683F9CB98|rigid:uVCrS41qjCGZdXoy5SqRa0r2qsU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:P50636 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508340|uniprotkb:Q3UGT2|uniprotkb:Q9QUJ5|ensembl:ENSMUSP00000022890 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:rn19a_mouse(display_long)|uniprotkb:Rnf19a(gene name)|psi-mi:Rnf19a(display_short)|uniprotkb:Geg-154(gene name synonym)|uniprotkb:Rnf19(gene name synonym)|uniprotkb:Xybp(gene name synonym)|uniprotkb:Double ring-finger protein(gene name synonym)|uniprotkb:Gametogenesis-expressed protein GEG-154(gene name synonym)|uniprotkb:RING finger protein 19A(gene name synonym)|uniprotkb:UBCM4-interacting protein 117(gene name synonym)|uniprotkb:XY body protein(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508743|imex:IM-16925-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_038951.1|ensembl:ENSMUSG00000022280(gene)|ensembl:ENSMUST00000022890(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:P50636|reactome:R-MMU-983168 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:kmmYnA5DGyrDuK1Px3uyV6iqlG810090 intact-crc:08C20F209B1C9105|rigid:WHvMsb2UBPNGdC8DeBRpLASF1NA false sufficient binding region:13-484 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16110 uniprotkb:Q9Z0P7 intact:EBI-3508325 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510275|imex:IM-16925-52 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:0065F1B5D9D36568|rigid:YE6eIYM0G+d7OHDDVnIFScXkeDQ false - sufficient binding region:13-484 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6IQX8 uniprotkb:Q6IQX8 intact:EBI-3044006|ensembl:ENSMUSP00000068184|ensembl:ENSMUSP00000126854|ensembl:ENSMUSP00000154709|uniprotkb:Q921W9|uniprotkb:Q924S6|uniprotkb:Q9CVF3|intact:EBI-3508329 intact:EBI-3044006|ensembl:ENSMUSP00000068184|ensembl:ENSMUSP00000126854|ensembl:ENSMUSP00000154709|uniprotkb:Q921W9|uniprotkb:Q924S6|uniprotkb:Q9CVF3|intact:EBI-3508329 psi-mi:zn219_mouse(display_long)|uniprotkb:Znf219(gene name)|psi-mi:Znf219(display_short)|uniprotkb:Zfp219(gene name synonym) psi-mi:zn219_mouse(display_long)|uniprotkb:Znf219(gene name)|psi-mi:Znf219(display_short)|uniprotkb:Zfp219(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508749|imex:IM-16925-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000049295(gene)|ensembl:ENSMUST00000067549(transcript)|ensembl:ENSMUST00000166169(transcript)|ensembl:ENSMUST00000226522(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060174"(limb bud formation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6IQX8|refseq:XP_011243478.1|refseq:XP_011243479.1|refseq:XP_017171669.1|refseq:NP_081524.2|refseq:NP_001240623.1|refseq:NP_001240624.1|refseq:XP_006519561.1|refseq:XP_006519562.1|refseq:XP_006519564.1|refseq:XP_006519565.1|refseq:XP_006519566.1|refseq:XP_006519567.1|refseq:XP_006519568.1 ensembl:ENSMUSG00000049295(gene)|ensembl:ENSMUST00000067549(transcript)|ensembl:ENSMUST00000166169(transcript)|ensembl:ENSMUST00000226522(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060174"(limb bud formation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6IQX8|refseq:XP_011243478.1|refseq:XP_011243479.1|refseq:XP_017171669.1|refseq:NP_081524.2|refseq:NP_001240623.1|refseq:NP_001240624.1|refseq:XP_006519561.1|refseq:XP_006519562.1|refseq:XP_006519564.1|refseq:XP_006519565.1|refseq:XP_006519566.1|refseq:XP_006519567.1|refseq:XP_006519568.1 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2018/01/16 rogid:Q6ebFbVDwgd46TS1dBOEk3kNYO410090 rogid:Q6ebFbVDwgd46TS1dBOEk3kNYO410090 intact-crc:8C208366943E0C91|rigid:lpKfpMnlT2U3YClvGmOHGKWWiBo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:Q9Z0P7 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509124|imex:IM-16925-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:790E1DF0F4CF3A49|rigid:3mNOnFLX97rnUy1SkHu+La+Lz+8 false sufficient binding region:13-484 sufficient binding region:110-325 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O09000 uniprotkb:Q9Z0P7 intact:EBI-3508338|uniprotkb:Q9CRD5 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509132|imex:IM-16925-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:EAED43F7C487A402|rigid:KU8Y8JAzo5uxZ6h5nbciHNiWOdM false - sufficient binding region:110-325 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49312 uniprotkb:Q9Z0P7 intact:EBI-642826|uniprotkb:P97312|uniprotkb:Q3V269|ensembl:ENSMUSP00000084609|ensembl:ENSMUSP00000155833 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:roa1_mouse(display_long)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:HDP-1(gene name synonym)|uniprotkb:Single-strand-binding protein(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed(gene name synonym)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Fli-2(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509137|imex:IM-16925-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034577.1|ensembl:ENSMUSG00000046434(gene)|ensembl:ENSMUST00000087351(transcript)|ensembl:ENSMUST00000230171(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0035198"(miRNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P49312|go:"GO:0008380"(RNA splicing)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:D59B4D898BF80A39|rigid:YO/YGRWIYvz2R8ctv1pJwRMj/XI false - sufficient binding region:110-325 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:O88974 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-79658|uniprotkb:Q6AXH8|uniprotkb:Q78N64|uniprotkb:Q78N65|uniprotkb:Q80U84|uniprotkb:Q8BTV6|uniprotkb:Q8CIX7|uniprotkb:Q922K1 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:setb1_mouse(display_long)|uniprotkb:Setdb1(gene name)|psi-mi:Setdb1(display_short)|uniprotkb:Eset(gene name synonym)|uniprotkb:Kiaa0067(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509142|imex:IM-16925-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0060348"(bone development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR001214(SET)|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|reactome:R-MMU-3214841|interpro:IPR002999(Tudor)|interpro:IPR025796 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:wopdjnSA/Ng9vtDW1AdBfPicNdo10090 intact-crc:1EF135C99B6C7130|rigid:AB1CfTn/OTYfJpDt7fpEVhjVmkA false sufficient binding region:110-325 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50636 uniprotkb:Q9Z0P7 intact:EBI-3508340|uniprotkb:Q3UGT2|uniprotkb:Q9QUJ5|ensembl:ENSMUSP00000022890 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:rn19a_mouse(display_long)|uniprotkb:Rnf19a(gene name)|psi-mi:Rnf19a(display_short)|uniprotkb:Geg-154(gene name synonym)|uniprotkb:Rnf19(gene name synonym)|uniprotkb:Xybp(gene name synonym)|uniprotkb:Double ring-finger protein(gene name synonym)|uniprotkb:Gametogenesis-expressed protein GEG-154(gene name synonym)|uniprotkb:RING finger protein 19A(gene name synonym)|uniprotkb:UBCM4-interacting protein 117(gene name synonym)|uniprotkb:XY body protein(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509147|imex:IM-16925-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038951.1|ensembl:ENSMUSG00000022280(gene)|ensembl:ENSMUST00000022890(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:P50636|reactome:R-MMU-983168 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:kmmYnA5DGyrDuK1Px3uyV6iqlG810090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:381ADC9CF4DBCFC1|rigid:WHvMsb2UBPNGdC8DeBRpLASF1NA false - sufficient binding region:110-325 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:O55128 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509184|imex:IM-16925-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:46A27AC04BD171D7|rigid:xc44E2MERaMfeYHBkNmIrvt4Jpw false - necessary binding region:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:P17095 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-912604|uniprotkb:Q91WV2|uniprotkb:Q924L7|uniprotkb:Q924L8|ensembl:ENSMUSP00000100667|ensembl:ENSMUSP00000113015|ensembl:ENSMUSP00000113916|ensembl:ENSMUSP00000155886|ensembl:ENSMUSP00000156173|ensembl:ENSMUSP00000156199 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:hmga1_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:Hmga1(gene name)|psi-mi:Hmga1(display_short)|uniprotkb:Hmgi(gene name synonym)|uniprotkb:Hmgiy(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509190|imex:IM-16925-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 ensembl:ENSMUSG00000046711(gene)|ensembl:ENSMUSG00000078249(gene)|ensembl:ENSMUST00000105046(transcript)|ensembl:ENSMUST00000118599(transcript)|ensembl:ENSMUST00000119486(transcript)|ensembl:ENSMUST00000231874(transcript)|ensembl:ENSMUST00000232013(transcript)|ensembl:ENSMUST00000232265(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030527"(structural constituent of chromatin)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|interpro:IPR031079|mint:P17095|reactome:R-MMU-2559584|refseq:NP_001020598.1|refseq:NP_001034445.1|refseq:NP_001159948.1|refseq:NP_001159949.1|refseq:NP_001160007.1|refseq:NP_001160008.1|refseq:NP_001160009.1|refseq:NP_001160011.1|refseq:NP_001160012.1|refseq:NP_001160013.1|refseq:NP_001160014.1|refseq:NP_057869.2|ensembl:ENSMUSG00000046711|dip:DIP-53N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:8GAWIHsX1UJjnQrxhZp9UTPLBTI10090 intact-crc:A7E255FBD936E37F|rigid:/toNKpXG9++imGNqExAoXSeBa0w false necessary binding region:326-484 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P53569 uniprotkb:Q9Z0P7 intact:EBI-3508342|uniprotkb:Q3TXW5|uniprotkb:Q3TYA8|uniprotkb:Q3UWQ7 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:cebpz_mouse(display_long)|uniprotkb:Cebpz(gene name)|psi-mi:Cebpz(display_short)|uniprotkb:Cbf2(gene name synonym)|uniprotkb:Cebpa-rs1(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509280|imex:IM-16925-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001019977.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR005612(CBF)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR040155|mint:P53569 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:Wtyo1AYcZKmhCYWq5lrc1Vo5i2A10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:76CE431A747258A7|rigid:f0PY51hw8gLmkt5dGUjJpD4n2hI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:O08709 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510176|imex:IM-16925-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090 intact-crc:56721355F51CF42C|rigid:jePM2hZLyjt8u9DYqlO47xdJe7Y false necessary binding region:326-484 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88653 uniprotkb:Q9Z0P7 intact:EBI-1039530|ensembl:ENSMUSP00000130811|ensembl:ENSMUSP00000142512 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:ltor3_mouse(display_long)|uniprotkb:Map2k1ip1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase 1-interacting protein 1(gene name synonym)|uniprotkb:Lamtor3(gene name)|psi-mi:Lamtor3(display_short)|uniprotkb:Mapbp(gene name synonym)|uniprotkb:MEK-binding partner 1(gene name synonym)|uniprotkb:Mapksp1(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase scaffold protein 1(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510180|imex:IM-16925-42 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064304.1|ensembl:ENSMUSG00000091512(gene)|ensembl:ENSMUST00000168345(transcript)|ensembl:ENSMUST00000197064(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR015019(Mitogen-activated protein kinase kinase 1 interacting)|mint:O88653|rcsb pdb:1VET|rcsb pdb:1VEU|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8943724|reactome:R-MMU-9639288 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:TSKaQ6Z8J4/87F1tOpftsh6xIvo10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:B50F2935488172B2|rigid:KZRUdTHRtCpDee0fBz8CQo81mLw false - necessary binding region:326-484 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88907 uniprotkb:Q9Z0P7 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510188|imex:IM-16925-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:B10EE68C82E771CC|rigid:Zvp4RZwaI5uBDNUQZJpWHiv7S4g false necessary binding region:326-484 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P23647 uniprotkb:Q9Z0P7 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510194|imex:IM-16925-44 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:505766DDAE9D6F58|rigid:uJC/HhyMAJYyyZAEyq6KZHeUBDQ false sufficient binding region:326-484 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:Q9VEX9 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510199|imex:IM-16925-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 intact-crc:48166135706B6033|rigid:YlPDlEccYLrRze+hda9pOQFUqSM false necessary binding region:13-325 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08151 uniprotkb:Q9VG38 intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8 intact:EBI-110605|ensemblmetazoa:FBpp0082134 psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym) psi-mi:q9vg38_drome(display_long)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:CG6054(orf name)|uniprotkb:Dmel\CG6054(gene name synonym)|uniprotkb:"SU(FU)"(gene name synonym)|uniprotkb:SUFU(gene name synonym)|uniprotkb:"Su(Fu)"(gene name synonym)|uniprotkb:SuFu(gene name synonym)|uniprotkb:Sufu(gene name synonym)|uniprotkb:dSufu(gene name synonym)|uniprotkb:"su(fu)"(gene name synonym)|uniprotkb:sufu(gene name synonym)|uniprotkb:Dmel_CG6054(orf name)|uniprotkb:d Sufu(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510204|imex:IM-16925-46 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N refseq:NP_536750.2|flybase:FBgn0005355|dip:DIP-60773N|ensemblmetazoa:FBgn0005355(gene)|ensemblmetazoa:FBtr0082665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|rcsb pdb:4KMA|rcsb pdb:6LPH|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606 rogid:bgRdXcd2LSsl7sfv4ArpqgWFzeU7227 intact-crc:0B18787D283CD0BD|rigid:IC1RfJvFr1pbutnzZi+d2pIYrPs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VG38 uniprotkb:O88907 intact:EBI-110605|ensemblmetazoa:FBpp0082134 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:q9vg38_drome(display_long)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:CG6054(orf name)|uniprotkb:Dmel\CG6054(gene name synonym)|uniprotkb:"SU(FU)"(gene name synonym)|uniprotkb:SUFU(gene name synonym)|uniprotkb:"Su(Fu)"(gene name synonym)|uniprotkb:SuFu(gene name synonym)|uniprotkb:Sufu(gene name synonym)|uniprotkb:dSufu(gene name synonym)|uniprotkb:"su(fu)"(gene name synonym)|uniprotkb:sufu(gene name synonym)|uniprotkb:Dmel_CG6054(orf name)|uniprotkb:d Sufu(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510208|imex:IM-16925-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536750.2|flybase:FBgn0005355|dip:DIP-60773N|ensemblmetazoa:FBgn0005355(gene)|ensemblmetazoa:FBtr0082665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|rcsb pdb:4KMA|rcsb pdb:6LPH|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:bgRdXcd2LSsl7sfv4ArpqgWFzeU7227 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:9AC397D2AD985AAB|rigid:FJOQmGsyYP70xS+6vQ8FYgFtHRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VG38 uniprotkb:P23647 intact:EBI-110605|ensemblmetazoa:FBpp0082134 intact:EBI-165536|ensemblmetazoa:FBpp0074373|uniprotkb:Q26346|uniprotkb:Q26347|uniprotkb:Q27412|uniprotkb:Q9VWR7 psi-mi:q9vg38_drome(display_long)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:CG6054(orf name)|uniprotkb:Dmel\CG6054(gene name synonym)|uniprotkb:"SU(FU)"(gene name synonym)|uniprotkb:SUFU(gene name synonym)|uniprotkb:"Su(Fu)"(gene name synonym)|uniprotkb:SuFu(gene name synonym)|uniprotkb:Sufu(gene name synonym)|uniprotkb:dSufu(gene name synonym)|uniprotkb:"su(fu)"(gene name synonym)|uniprotkb:sufu(gene name synonym)|uniprotkb:Dmel_CG6054(orf name)|uniprotkb:d Sufu(gene name synonym) psi-mi:fused_drome(display_long)|uniprotkb:fu(gene name)|psi-mi:fu(display_short)|uniprotkb:CG6551(orf name) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510212|imex:IM-16925-48 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_536750.2|flybase:FBgn0005355|dip:DIP-60773N|ensemblmetazoa:FBgn0005355(gene)|ensemblmetazoa:FBtr0082665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|rcsb pdb:4KMA|rcsb pdb:6LPH|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684 ensemblmetazoa:FBgn0001079(gene)|ensemblmetazoa:FBtr0074602(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007228"(positive regulation of hh target transcription factor activity)|go:"GO:0007293"(germarium-derived egg chamber formation)|go:"GO:0007367"(segment polarity determination)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035222"(wing disc pattern formation)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005119"(smoothened binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:6LPH|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-216119|reactome:R-DME-216217|refseq:NP_477499.1|flybase:FBgn0001079|dip:DIP-492N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:bgRdXcd2LSsl7sfv4ArpqgWFzeU7227 rogid:5KrFb8xuGHpjwIlFMx4AkeD9/m47227 intact-crc:C1DC78CD9733E0D7|rigid:7HVwSLS2cRCRCJPL81JAs0bg3Q4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08151 uniprotkb:O09000 intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510282|imex:IM-16925-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:9B5BC258343CD628|rigid:To11izJkAsegqXcFmVl7+OZPjQU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O09000 uniprotkb:O09000 intact:EBI-3508338|uniprotkb:Q9CRD5 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510306|imex:IM-16925-54 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:B1D538113773ABF3|rigid:UZ1caPK+z1yZltGmhlSk6D3eCKM false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49312 uniprotkb:O09000 intact:EBI-642826|uniprotkb:P97312|uniprotkb:Q3V269|ensembl:ENSMUSP00000084609|ensembl:ENSMUSP00000155833 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:roa1_mouse(display_long)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:HDP-1(gene name synonym)|uniprotkb:Single-strand-binding protein(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed(gene name synonym)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Fli-2(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510364|imex:IM-16925-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034577.1|ensembl:ENSMUSG00000046434(gene)|ensembl:ENSMUST00000087351(transcript)|ensembl:ENSMUST00000230171(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0035198"(miRNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P49312|go:"GO:0008380"(RNA splicing)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203 go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI10090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:14BC185EE9389409|rigid:kP5C8VyYUEe/iD5qD5pbJetAedY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50636 uniprotkb:O09000 intact:EBI-3508340|uniprotkb:Q3UGT2|uniprotkb:Q9QUJ5|ensembl:ENSMUSP00000022890 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:rn19a_mouse(display_long)|uniprotkb:Rnf19a(gene name)|psi-mi:Rnf19a(display_short)|uniprotkb:Geg-154(gene name synonym)|uniprotkb:Rnf19(gene name synonym)|uniprotkb:Xybp(gene name synonym)|uniprotkb:Double ring-finger protein(gene name synonym)|uniprotkb:Gametogenesis-expressed protein GEG-154(gene name synonym)|uniprotkb:RING finger protein 19A(gene name synonym)|uniprotkb:UBCM4-interacting protein 117(gene name synonym)|uniprotkb:XY body protein(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510390|imex:IM-16925-56 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038951.1|ensembl:ENSMUSG00000022280(gene)|ensembl:ENSMUST00000022890(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:P50636|reactome:R-MMU-983168 go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:kmmYnA5DGyrDuK1Px3uyV6iqlG810090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:5ABBBAFBE80027AA|rigid:5oF23QrW3If0+MXitZl2aWzPQD0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88974 uniprotkb:O09000 intact:EBI-79658|uniprotkb:Q6AXH8|uniprotkb:Q78N64|uniprotkb:Q78N65|uniprotkb:Q80U84|uniprotkb:Q8BTV6|uniprotkb:Q8CIX7|uniprotkb:Q922K1 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:setb1_mouse(display_long)|uniprotkb:Setdb1(gene name)|psi-mi:Setdb1(display_short)|uniprotkb:Eset(gene name synonym)|uniprotkb:Kiaa0067(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510394|imex:IM-16925-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0060348"(bone development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR001214(SET)|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|reactome:R-MMU-3214841|interpro:IPR002999(Tudor)|interpro:IPR025796 go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:wopdjnSA/Ng9vtDW1AdBfPicNdo10090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:FE4421ABEB9D0B7C|rigid:4oPJ92tVeztetqdyaG/AflLiO7E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O09000 uniprotkb:Q6IQX8 intact:EBI-3508338|uniprotkb:Q9CRD5 intact:EBI-3044006|ensembl:ENSMUSP00000068184|ensembl:ENSMUSP00000126854|ensembl:ENSMUSP00000154709|uniprotkb:Q921W9|uniprotkb:Q924S6|uniprotkb:Q9CVF3|intact:EBI-3508329 psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:zn219_mouse(display_long)|uniprotkb:Znf219(gene name)|psi-mi:Znf219(display_short)|uniprotkb:Zfp219(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510398|imex:IM-16925-58 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 ensembl:ENSMUSG00000049295(gene)|ensembl:ENSMUST00000067549(transcript)|ensembl:ENSMUST00000166169(transcript)|ensembl:ENSMUST00000226522(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060174"(limb bud formation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6IQX8|refseq:XP_011243478.1|refseq:XP_011243479.1|refseq:XP_017171669.1|refseq:NP_081524.2|refseq:NP_001240623.1|refseq:NP_001240624.1|refseq:XP_006519561.1|refseq:XP_006519562.1|refseq:XP_006519564.1|refseq:XP_006519565.1|refseq:XP_006519566.1|refseq:XP_006519567.1|refseq:XP_006519568.1 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2018/01/16 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 rogid:Q6ebFbVDwgd46TS1dBOEk3kNYO410090 intact-crc:8F1F57684D13A5DA|rigid:ImAM7tK3A7rnr9bgZAKolZsGqYk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16110 uniprotkb:O09000 intact:EBI-3508325 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510402|imex:IM-16925-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:C7B1DA6FE9A483F6|rigid:llscsKB5p5VQYb/VHSfaIqw68OE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O09000 uniprotkb:O55128 intact:EBI-3508338|uniprotkb:Q9CRD5 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510421|imex:IM-16925-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:C555D4B2E8D40C6A|rigid:j5giBLKDM5vGUh+btFc5ibg41S0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08709 uniprotkb:O09000 intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510425|imex:IM-16925-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen) go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:C2A9C9B4F84FEE69|rigid:fngS1wcq4We1pG/bHMGU1wL029M false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88653 uniprotkb:O09000 intact:EBI-1039530|ensembl:ENSMUSP00000130811|ensembl:ENSMUSP00000142512 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:ltor3_mouse(display_long)|uniprotkb:Map2k1ip1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase 1-interacting protein 1(gene name synonym)|uniprotkb:Lamtor3(gene name)|psi-mi:Lamtor3(display_short)|uniprotkb:Mapbp(gene name synonym)|uniprotkb:MEK-binding partner 1(gene name synonym)|uniprotkb:Mapksp1(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase scaffold protein 1(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510430|imex:IM-16925-62 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064304.1|ensembl:ENSMUSG00000091512(gene)|ensembl:ENSMUST00000168345(transcript)|ensembl:ENSMUST00000197064(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR015019(Mitogen-activated protein kinase kinase 1 interacting)|mint:O88653|rcsb pdb:1VET|rcsb pdb:1VEU|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8943724|reactome:R-MMU-9639288 go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:TSKaQ6Z8J4/87F1tOpftsh6xIvo10090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:F71721ABEA77A6E1|rigid:6dZtPypaegg4x1X1CPtlz/T6boc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88907 uniprotkb:O09000 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510434|imex:IM-16925-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:E54421ABEB4EFD9E|rigid:N4iR4ShDNszZimnR2I257a3dt1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50636 uniprotkb:O88907 intact:EBI-3508340|uniprotkb:Q3UGT2|uniprotkb:Q9QUJ5|ensembl:ENSMUSP00000022890 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:rn19a_mouse(display_long)|uniprotkb:Rnf19a(gene name)|psi-mi:Rnf19a(display_short)|uniprotkb:Geg-154(gene name synonym)|uniprotkb:Rnf19(gene name synonym)|uniprotkb:Xybp(gene name synonym)|uniprotkb:Double ring-finger protein(gene name synonym)|uniprotkb:Gametogenesis-expressed protein GEG-154(gene name synonym)|uniprotkb:RING finger protein 19A(gene name synonym)|uniprotkb:UBCM4-interacting protein 117(gene name synonym)|uniprotkb:XY body protein(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510439|imex:IM-16925-64 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038951.1|ensembl:ENSMUSG00000022280(gene)|ensembl:ENSMUST00000022890(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:P50636|reactome:R-MMU-983168 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:kmmYnA5DGyrDuK1Px3uyV6iqlG810090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:D7CFAE410B4C29B5|rigid:h5HKTSWTNvIgM/EUGN8s63Td0GA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:O55128 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510447|imex:IM-16925-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:2AC4927D2D4D1CF3|rigid:xc44E2MERaMfeYHBkNmIrvt4Jpw false sufficient binding region:13-384 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17095 uniprotkb:O55128 intact:EBI-912604|uniprotkb:Q91WV2|uniprotkb:Q924L7|uniprotkb:Q924L8|ensembl:ENSMUSP00000100667|ensembl:ENSMUSP00000113015|ensembl:ENSMUSP00000113916|ensembl:ENSMUSP00000155886|ensembl:ENSMUSP00000156173|ensembl:ENSMUSP00000156199 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:hmga1_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:Hmga1(gene name)|psi-mi:Hmga1(display_short)|uniprotkb:Hmgi(gene name synonym)|uniprotkb:Hmgiy(gene name synonym) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510453|imex:IM-16925-66 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000046711(gene)|ensembl:ENSMUSG00000078249(gene)|ensembl:ENSMUST00000105046(transcript)|ensembl:ENSMUST00000118599(transcript)|ensembl:ENSMUST00000119486(transcript)|ensembl:ENSMUST00000231874(transcript)|ensembl:ENSMUST00000232013(transcript)|ensembl:ENSMUST00000232265(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030527"(structural constituent of chromatin)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|interpro:IPR031079|mint:P17095|reactome:R-MMU-2559584|refseq:NP_001020598.1|refseq:NP_001034445.1|refseq:NP_001159948.1|refseq:NP_001159949.1|refseq:NP_001160007.1|refseq:NP_001160008.1|refseq:NP_001160009.1|refseq:NP_001160011.1|refseq:NP_001160012.1|refseq:NP_001160013.1|refseq:NP_001160014.1|refseq:NP_057869.2|ensembl:ENSMUSG00000046711|dip:DIP-53N refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:8GAWIHsX1UJjnQrxhZp9UTPLBTI10090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:7D92E21B0FC38140|rigid:T9qa2mt189xlSh+zhPwbk26Lfxk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88907 uniprotkb:P08151 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-308084|uniprotkb:Q8TDN9|ensembl:ENSP00000228682|uniprotkb:D0EUY3|uniprotkb:E9PQQ9|uniprotkb:F5H6H8 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:gli1_human(display_long)|uniprotkb:GLI1(gene name)|psi-mi:GLI1(display_short)|uniprotkb:GLI(gene name synonym)|uniprotkb:Glioma-associated oncogene(gene name synonym)|uniprotkb:Oncogene GLI(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510463|imex:IM-16925-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N refseq:NP_001161081.1|ensembl:ENSG00000111087(gene)|ensembl:ENST00000228682(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007418"(ventral midline development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0009611"(response to wounding)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0021696"(cerebellar cortex morphogenesis)|go:"GO:0021938"(smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030850"(prostate gland development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_001153517.1|refseq:NP_005260.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0060032"(notochord regression)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000345"(regulation of hepatocyte proliferation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032850|interpro:IPR036236|interpro:IPR043359|rcsb pdb:2GLI|rcsb pdb:4BLB|rcsb pdb:4KMD|rcsb pdb:5OM0|reactome:R-HSA-5610780|reactome:R-HSA-5610787|reactome:R-HSA-5632684|reactome:R-HSA-5635851|refseq:XP_011536491.1|ensembl:ENSP00000228682|ensembl:ENST00000528467|ensembl:ENSP00000434408|ensembl:ENST00000543426|ensembl:ENSP00000437607|ensembl:ENST00000546141|ensembl:ENSP00000441006|dip:DIP-32536N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:XMxc3WAzq0JCpu49dMsG/I+09B09606 intact-crc:B73E0B78D991E2DE|rigid:9JeLJIT4F4lqBj8H7OeNfVx1kVU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10071 uniprotkb:O88907 intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510467|imex:IM-16925-68 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:A3820CDDD9917E85|rigid:igk3i5OOKjHASRaJVeVsyOIWENI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88907 uniprotkb:O09000 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510471|imex:IM-16925-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:4455FC31E5AFC777|rigid:N4iR4ShDNszZimnR2I257a3dt1o false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P49312 uniprotkb:O88907 intact:EBI-642826|uniprotkb:P97312|uniprotkb:Q3V269|ensembl:ENSMUSP00000084609|ensembl:ENSMUSP00000155833 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:roa1_mouse(display_long)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:HDP-1(gene name synonym)|uniprotkb:Single-strand-binding protein(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed(gene name synonym)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Fli-2(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510476|imex:IM-16925-70 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034577.1|ensembl:ENSMUSG00000046434(gene)|ensembl:ENSMUST00000087351(transcript)|ensembl:ENSMUST00000230171(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0035198"(miRNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P49312|go:"GO:0008380"(RNA splicing)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI10090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:71B3934E9CA41543|rigid:Hfs9Bmd672cKILdVZ+48TEBtYJw false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88974 uniprotkb:O88907 intact:EBI-79658|uniprotkb:Q6AXH8|uniprotkb:Q78N64|uniprotkb:Q78N65|uniprotkb:Q80U84|uniprotkb:Q8BTV6|uniprotkb:Q8CIX7|uniprotkb:Q922K1 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:setb1_mouse(display_long)|uniprotkb:Setdb1(gene name)|psi-mi:Setdb1(display_short)|uniprotkb:Eset(gene name synonym)|uniprotkb:Kiaa0067(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510479|imex:IM-16925-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0060348"(bone development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR001214(SET)|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|reactome:R-MMU-3214841|interpro:IPR002999(Tudor)|interpro:IPR025796 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:wopdjnSA/Ng9vtDW1AdBfPicNdo10090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:93332919DBE759C9|rigid:EjRDB2fZsbxBICvFbNjMFEPkefQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6IQX8 uniprotkb:O88907 intact:EBI-3044006|ensembl:ENSMUSP00000068184|ensembl:ENSMUSP00000126854|ensembl:ENSMUSP00000154709|uniprotkb:Q921W9|uniprotkb:Q924S6|uniprotkb:Q9CVF3|intact:EBI-3508329 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:zn219_mouse(display_long)|uniprotkb:Znf219(gene name)|psi-mi:Znf219(display_short)|uniprotkb:Zfp219(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510483|imex:IM-16925-72 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000049295(gene)|ensembl:ENSMUST00000067549(transcript)|ensembl:ENSMUST00000166169(transcript)|ensembl:ENSMUST00000226522(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060174"(limb bud formation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6IQX8|refseq:XP_011243478.1|refseq:XP_011243479.1|refseq:XP_017171669.1|refseq:NP_081524.2|refseq:NP_001240623.1|refseq:NP_001240624.1|refseq:XP_006519561.1|refseq:XP_006519562.1|refseq:XP_006519564.1|refseq:XP_006519565.1|refseq:XP_006519566.1|refseq:XP_006519567.1|refseq:XP_006519568.1 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2018/01/16 rogid:Q6ebFbVDwgd46TS1dBOEk3kNYO410090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:E2685FDA7D69F76F|rigid:yRP5+/At6kNiEJf/fTjcy3GoGds false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P16110 uniprotkb:O88907 intact:EBI-3508325 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510487|imex:IM-16925-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:AAC6D2DDD9DED143|rigid:+xLQdjG7F1ZyPoz8g1qpsFSrvD4 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O55128 uniprotkb:O88907 intact:EBI-3508332|uniprotkb:Q545L4 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510492|imex:IM-16925-74 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:0CEEA0D7DF6BF6E1|rigid:7PJ1xGKirEloUlWymEDycHoHofE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88653 uniprotkb:O88907 intact:EBI-1039530|ensembl:ENSMUSP00000130811|ensembl:ENSMUSP00000142512 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:ltor3_mouse(display_long)|uniprotkb:Map2k1ip1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase 1-interacting protein 1(gene name synonym)|uniprotkb:Lamtor3(gene name)|psi-mi:Lamtor3(display_short)|uniprotkb:Mapbp(gene name synonym)|uniprotkb:MEK-binding partner 1(gene name synonym)|uniprotkb:Mapksp1(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase scaffold protein 1(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510496|imex:IM-16925-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064304.1|ensembl:ENSMUSG00000091512(gene)|ensembl:ENSMUST00000168345(transcript)|ensembl:ENSMUST00000197064(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR015019(Mitogen-activated protein kinase kinase 1 interacting)|mint:O88653|rcsb pdb:1VET|rcsb pdb:1VEU|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8943724|reactome:R-MMU-9639288 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:TSKaQ6Z8J4/87F1tOpftsh6xIvo10090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:D45437F6EE92F273|rigid:Y9PJOBgKf5/vuvfYMJhpyDX2Tas false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19538 uniprotkb:O88907 intact:EBI-94976|uniprotkb:O18525|uniprotkb:Q8T6T1|uniprotkb:Q9V4A8|ensemblmetazoa:FBpp0088245 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:ci_drome(display_long)|uniprotkb:ci(gene name)|psi-mi:ci(display_short)|uniprotkb:ci-D(gene name synonym)|uniprotkb:CG2125(orf name)|uniprotkb:ci form of 155 kDa(gene name synonym)|uniprotkb:ci full-length protein(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510500|imex:IM-16925-76 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524617.3|flybase:FBgn0004859|ensemblmetazoa:FBgn0004859(gene)|ensemblmetazoa:FBtr0089178(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002385"(mucosal immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007367"(segment polarity determination)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035017"(cuticle pattern formation)|go:"GO:0035217"(labial disc development)|go:"GO:0035224"(genital disc anterior/posterior pattern formation)|go:"GO:0035277"(spiracle morphogenesis, open tracheal system)|go:"GO:0035301"(Hedgehog signaling complex)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048100"(wing disc anterior/posterior pattern formation)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000495"(regulation of cell proliferation involved in compound eye morphogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043359|rcsb pdb:3HQM|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209338|reactome:R-DME-209360|reactome:R-DME-209446|reactome:R-DME-216119|reactome:R-DME-216167|reactome:R-DME-216217|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684|go:"GO:0060914"(heart formation)|dip:DIP-121N refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:OECmiJznkWySH07yEHq3R8HSsAQ7227 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:03E181DDDBAE11EF|rigid:s4rZd4NxCBUWy2g3QlLv38y6U8k false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VEX9 uniprotkb:O88907 intact:EBI-129424|uniprotkb:Q1LYZ7|uniprotkb:Q8SZF6|uniprotkb:Q9N9Z3|ensemblmetazoa:FBpp0082731|ensemblmetazoa:FBpp0312505|ensemblmetazoa:FBpp0312506 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:sap18_drome(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:SAP18(gene name synonym)|uniprotkb:CG6046(orf name)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Bicoid-interacting protein 1(gene name synonym)|uniprotkb:dSAP18(gene name synonym) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510504|imex:IM-16925-77 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_524377.1|flybase:FBgn0024491|ensemblmetazoa:FBgn0024491(gene)|ensemblmetazoa:FBtr0083279(transcript)|ensemblmetazoa:FBtr0347200(transcript)|ensemblmetazoa:FBtr0347201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006342"|go:"GO:0008134"(transcription factor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|reactome:R-DME-3214815|refseq:NP_001303440.1|refseq:NP_001303441.1|dip:DIP-19160N refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:RFGSqMzmsSlbwQuNCIFDtfG1eDc7227 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:128A8BDA7EF12D80|rigid:RUElqoVgm7S6rPHA/wB3rTqoLmA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O88907 uniprotkb:Q9VG38 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-110605|ensemblmetazoa:FBpp0082134 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:q9vg38_drome(display_long)|uniprotkb:"Su(fu)"(gene name)|psi-mi:"Su(fu)"(display_short)|uniprotkb:CG6054(orf name)|uniprotkb:Dmel\CG6054(gene name synonym)|uniprotkb:"SU(FU)"(gene name synonym)|uniprotkb:SUFU(gene name synonym)|uniprotkb:"Su(Fu)"(gene name synonym)|uniprotkb:SuFu(gene name synonym)|uniprotkb:Sufu(gene name synonym)|uniprotkb:dSufu(gene name synonym)|uniprotkb:"su(fu)"(gene name synonym)|uniprotkb:sufu(gene name synonym)|uniprotkb:Dmel_CG6054(orf name)|uniprotkb:d Sufu(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3510509|imex:IM-16925-78 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N refseq:NP_536750.2|flybase:FBgn0005355|dip:DIP-60773N|ensemblmetazoa:FBgn0005355(gene)|ensemblmetazoa:FBtr0082665(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046823"(negative regulation of nucleocytoplasmic transport)|go:"GO:0140311"(protein sequestering activity)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|rcsb pdb:4KMA|rcsb pdb:6LPH|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-5610787|reactome:R-DME-5632684 - - - figure legend:Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:bgRdXcd2LSsl7sfv4ArpqgWFzeU7227 intact-crc:7AC08BDA7EAE0601|rigid:FJOQmGsyYP70xS+6vQ8FYgFtHRo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9Z0P7 uniprotkb:O55128 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3508842|imex:IM-16925-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:B8D581A880F820AD|rigid:xc44E2MERaMfeYHBkNmIrvt4Jpw false sufficient binding region:2-484|green fluorescent protein tag:?-? his tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Z0P7 uniprotkb:O55128 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509269|imex:IM-16925-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Fig. 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:F80F4C3FBD6B4673|rigid:xc44E2MERaMfeYHBkNmIrvt4Jpw false green fluorescent protein tag:?-?|sufficient binding region:2-484 his tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Z0P7 uniprotkb:P16110 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508325 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:"MI:0096"(pull down) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-3508880|imex:IM-16925-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 - - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 intact-crc:05F34F5CFBBA6961|rigid:YE6eIYM0G+d7OHDDVnIFScXkeDQ false glutathione s tranferase tag:?-? 35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P16110 uniprotkb:Q9Z0P7 intact:EBI-3508325 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3508909|imex:IM-16925-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 go:"GO:0005634"(nucleus) - - comment:Upon co-transfection, nuclear leg3 level decreased and proteins accumulated in cytoplasm where it colocalized with sufu in 61% of double-labelled cells.|inhibition:LMB treatment blocks the effect of sufu on the cytoplasmic localization of leg3.|figure legend:Fig. 6H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/02/08 2014/10/16 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:814B57190F04134F|rigid:YE6eIYM0G+d7OHDDVnIFScXkeDQ false tag:n-n sufficient binding region:2-484|green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O55128 uniprotkb:Q9Z0P7 intact:EBI-3508332|uniprotkb:Q545L4 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-3508926|imex:IM-16925-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 go:"GO:0005634"(nucleus) - - comment:Upon co-transfection, sufu translocated to the nucleus and colocalized with sap18 in 67% of cells.|figure legend:Fig. 6J|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2011/02/08 2014/10/16 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:1EF5A9D9086385BD|rigid:xc44E2MERaMfeYHBkNmIrvt4Jpw false tag:n-n sufficient binding region:2-484|green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:O88974 uniprotkb:Q9Z0P7 intact:EBI-79658|uniprotkb:Q6AXH8|uniprotkb:Q78N64|uniprotkb:Q78N65|uniprotkb:Q80U84|uniprotkb:Q8BTV6|uniprotkb:Q8CIX7|uniprotkb:Q922K1 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:setb1_mouse(display_long)|uniprotkb:Setdb1(gene name)|psi-mi:Setdb1(display_short)|uniprotkb:Eset(gene name synonym)|uniprotkb:Kiaa0067(gene name synonym)|uniprotkb:SET domain bifurcated 1(gene name synonym)|uniprotkb:ERG-associated protein with SET domain(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509352|imex:IM-16925-34 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0060348"(bone development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR001214(SET)|interpro:IPR040880|interpro:IPR041291|interpro:IPR041292|reactome:R-MMU-3214841|interpro:IPR002999(Tudor)|interpro:IPR025796 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:wopdjnSA/Ng9vtDW1AdBfPicNdo10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:50E5176316A0C471|rigid:AB1CfTn/OTYfJpDt7fpEVhjVmkA false sufficient binding region:1119-1307 sufficient binding region:13-484 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0P7 uniprotkb:O88653 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-1039530|ensembl:ENSMUSP00000130811|ensembl:ENSMUSP00000142512 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:ltor3_mouse(display_long)|uniprotkb:Map2k1ip1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase 1-interacting protein 1(gene name synonym)|uniprotkb:Lamtor3(gene name)|psi-mi:Lamtor3(display_short)|uniprotkb:Mapbp(gene name synonym)|uniprotkb:MEK-binding partner 1(gene name synonym)|uniprotkb:Mapksp1(gene name synonym)|uniprotkb:Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3(gene name synonym)|uniprotkb:Mitogen-activated protein kinase scaffold protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509421|imex:IM-16925-40 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_064304.1|ensembl:ENSMUSG00000091512(gene)|ensembl:ENSMUST00000168345(transcript)|ensembl:ENSMUST00000197064(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005770"(late endosome)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071986"(Ragulator complex)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR015019(Mitogen-activated protein kinase kinase 1 interacting)|mint:O88653|rcsb pdb:1VET|rcsb pdb:1VEU|reactome:R-MMU-1632852|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-5674135|reactome:R-MMU-6798695|reactome:R-MMU-8943724|reactome:R-MMU-9639288 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:TSKaQ6Z8J4/87F1tOpftsh6xIvo10090 intact-crc:D6B81B5CE106512D|rigid:KZRUdTHRtCpDee0fBz8CQo81mLw false sufficient binding region:13-484 sufficient binding region:1-34,79-124 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P17095 uniprotkb:Q9Z0P7 intact:EBI-912604|uniprotkb:Q91WV2|uniprotkb:Q924L7|uniprotkb:Q924L8|ensembl:ENSMUSP00000100667|ensembl:ENSMUSP00000113015|ensembl:ENSMUSP00000113916|ensembl:ENSMUSP00000155886|ensembl:ENSMUSP00000156173|ensembl:ENSMUSP00000156199 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:hmga1_mouse(display_long)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:Hmga1(gene name)|psi-mi:Hmga1(display_short)|uniprotkb:Hmgi(gene name synonym)|uniprotkb:Hmgiy(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509409|imex:IM-16925-38 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000046711(gene)|ensembl:ENSMUSG00000078249(gene)|ensembl:ENSMUST00000105046(transcript)|ensembl:ENSMUST00000118599(transcript)|ensembl:ENSMUST00000119486(transcript)|ensembl:ENSMUST00000231874(transcript)|ensembl:ENSMUST00000232013(transcript)|ensembl:ENSMUST00000232265(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030527"(structural constituent of chromatin)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|interpro:IPR031079|mint:P17095|reactome:R-MMU-2559584|refseq:NP_001020598.1|refseq:NP_001034445.1|refseq:NP_001159948.1|refseq:NP_001159949.1|refseq:NP_001160007.1|refseq:NP_001160008.1|refseq:NP_001160009.1|refseq:NP_001160011.1|refseq:NP_001160012.1|refseq:NP_001160013.1|refseq:NP_001160014.1|refseq:NP_057869.2|ensembl:ENSMUSG00000046711|dip:DIP-53N refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:8GAWIHsX1UJjnQrxhZp9UTPLBTI10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:E7E55FB93494A6E8|rigid:/toNKpXG9++imGNqExAoXSeBa0w false - sufficient binding region:13-484 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0P7 uniprotkb:Q9QZQ8 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508334|uniprotkb:Q91VZ2|uniprotkb:Q9QZQ7|ensembl:ENSMUSP00000016081 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:h2ay_mouse(display_long)|uniprotkb:Macroh2a1(gene name)|psi-mi:Macroh2a1(display_short)|uniprotkb:H2A.y(gene name synonym)|uniprotkb:H2A/y(gene name synonym)|uniprotkb:H2afy(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509399|imex:IM-16925-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_001152985.1|refseq:NP_001152986.1|refseq:NP_001152987.1|refseq:NP_036145.1|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:0005730"(nucleolus)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|go:"GO:0005813"(centrosome)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|interpro:IPR032454|go:"GO:0007549"(dosage compensation)|interpro:IPR035796|interpro:IPR043472|mint:Q9QZQ8|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|ensembl:ENSMUSG00000015937(gene)|ensembl:ENSMUST00000016081(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding) - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:70q7YQGYxyE7ZBq8e7oOsIUSY0810090 intact-crc:38EC6CC9091462C7|rigid:LfAaFjUDbr0EV7TtU0SWwszVIiM false sufficient binding region:13-484 sufficient binding region:15-372 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0P7 uniprotkb:O88907 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509392|imex:IM-16925-36 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 intact-crc:89EB458B09E33D7F|rigid:Zvp4RZwaI5uBDNUQZJpWHiv7S4g false sufficient binding region:13-484 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0P7 uniprotkb:Q6IQX8 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3044006|ensembl:ENSMUSP00000068184|ensembl:ENSMUSP00000126854|ensembl:ENSMUSP00000154709|uniprotkb:Q921W9|uniprotkb:Q924S6|uniprotkb:Q9CVF3|intact:EBI-3508329 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:zn219_mouse(display_long)|uniprotkb:Znf219(gene name)|psi-mi:Znf219(display_short)|uniprotkb:Zfp219(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509383|imex:IM-16925-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 ensembl:ENSMUSG00000049295(gene)|ensembl:ENSMUST00000067549(transcript)|ensembl:ENSMUST00000166169(transcript)|ensembl:ENSMUST00000226522(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030154"(cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060174"(limb bud formation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6IQX8|refseq:XP_011243478.1|refseq:XP_011243479.1|refseq:XP_017171669.1|refseq:NP_081524.2|refseq:NP_001240623.1|refseq:NP_001240624.1|refseq:XP_006519561.1|refseq:XP_006519562.1|refseq:XP_006519564.1|refseq:XP_006519565.1|refseq:XP_006519566.1|refseq:XP_006519567.1|refseq:XP_006519568.1 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2018/01/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:Q6ebFbVDwgd46TS1dBOEk3kNYO410090 intact-crc:91026FC40C532B85|rigid:13hDyfsT09jXsKiyDsInJqf7yzM false sufficient binding region:13-484 sufficient binding region:430-726 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0P7 uniprotkb:P53569 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508342|uniprotkb:Q3TXW5|uniprotkb:Q3TYA8|uniprotkb:Q3UWQ7 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:cebpz_mouse(display_long)|uniprotkb:Cebpz(gene name)|psi-mi:Cebpz(display_short)|uniprotkb:Cbf2(gene name synonym)|uniprotkb:Cebpa-rs1(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509292|imex:IM-16925-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_001019977.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR005612(CBF)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR040155|mint:P53569 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:Wtyo1AYcZKmhCYWq5lrc1Vo5i2A10090 intact-crc:D3F9DFD32514D52A|rigid:f0PY51hw8gLmkt5dGUjJpD4n2hI false sufficient binding region:13-484 sufficient binding region:886-997 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P50636 uniprotkb:Q9Z0P7 intact:EBI-3508340|uniprotkb:Q3UGT2|uniprotkb:Q9QUJ5|ensembl:ENSMUSP00000022890 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:rn19a_mouse(display_long)|uniprotkb:Rnf19a(gene name)|psi-mi:Rnf19a(display_short)|uniprotkb:Geg-154(gene name synonym)|uniprotkb:Rnf19(gene name synonym)|uniprotkb:Xybp(gene name synonym)|uniprotkb:Double ring-finger protein(gene name synonym)|uniprotkb:Gametogenesis-expressed protein GEG-154(gene name synonym)|uniprotkb:RING finger protein 19A(gene name synonym)|uniprotkb:UBCM4-interacting protein 117(gene name synonym)|uniprotkb:XY body protein(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509342|imex:IM-16925-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038951.1|ensembl:ENSMUSG00000022280(gene)|ensembl:ENSMUST00000022890(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR031127|interpro:IPR044066|mint:P50636|reactome:R-MMU-983168 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:kmmYnA5DGyrDuK1Px3uyV6iqlG810090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:EB1F1207AC7E2B43|rigid:WHvMsb2UBPNGdC8DeBRpLASF1NA false sufficient binding region:490-840 sufficient binding region:13-484 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P49312 uniprotkb:Q9Z0P7 intact:EBI-642826|uniprotkb:P97312|uniprotkb:Q3V269|ensembl:ENSMUSP00000084609|ensembl:ENSMUSP00000155833 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:roa1_mouse(display_long)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:HDP-1(gene name synonym)|uniprotkb:Single-strand-binding protein(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed(gene name synonym)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Fli-2(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509321|imex:IM-16925-32 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_034577.1|ensembl:ENSMUSG00000046434(gene)|ensembl:ENSMUST00000087351(transcript)|ensembl:ENSMUST00000230171(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0035198"(miRNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P49312|go:"GO:0008380"(RNA splicing)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI10090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:1E283EAC72196E72|rigid:YO/YGRWIYvz2R8ctv1pJwRMj/XI false sufficient binding region:27-320 sufficient binding region:13-484 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0P7 uniprotkb:O09000 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508338|uniprotkb:Q9CRD5 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:ncoa3_mouse(display_long)|uniprotkb:Ncoa3(gene name)|psi-mi:Ncoa3(display_short)|uniprotkb:Aib1(gene name synonym)|uniprotkb:Pcip(gene name synonym)|uniprotkb:Rac3(gene name synonym)|uniprotkb:Tram1(gene name synonym)|uniprotkb:Amplified in breast cancer-1 protein homolog(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509315|imex:IM-16925-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|reactome:R-MMU-5687128|reactome:R-MMU-9018519|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033145"(positive regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060068"(vagina development)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0072091"(regulation of stem cell proliferation)|dip:DIP-44921N|mint:O09000 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:kUBr4kzfOKOmyqLPHkFpp4vQQ5s10090 intact-crc:68E72D34287E5F82|rigid:KU8Y8JAzo5uxZ6h5nbciHNiWOdM false sufficient binding region:13-484 sufficient binding region:17-989 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9Z0P7 uniprotkb:O55128 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 intact:EBI-3508332|uniprotkb:Q545L4 psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:sap18_mouse(display_long)|uniprotkb:Sap18(gene name)|psi-mi:Sap18(display_short)|uniprotkb:18 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p18(gene name synonym) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509309|imex:IM-16925-30 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 refseq:NP_033145.2|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|rcsb pdb:4A6Q|rcsb pdb:4A8X|rcsb pdb:4A90|reactome:R-MMU-3214815|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR010516(Sin3 associated polypeptide p18)|interpro:IPR017250(Histone deacetylase complex, SAP18 subunit)|interpro:IPR042534|mint:O55128|dip:DIP-59924N - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 rogid:qu0pMoROzO2IUdWgEvY0KzY0Eqk10090 intact-crc:3D2E057775EF9455|rigid:xc44E2MERaMfeYHBkNmIrvt4Jpw false sufficient binding region:13-484 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P16110 uniprotkb:Q9Z0P7 intact:EBI-3508325 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:leg3_mouse(display_long)|uniprotkb:Lgals3(gene name)|psi-mi:Lgals3(display_short)|uniprotkb:35 kDa lectin(gene name synonym)|uniprotkb:Carbohydrate-binding protein 35(gene name synonym)|uniprotkb:Galactose-specific lectin 3(gene name synonym)|uniprotkb:IgE-binding protein(gene name synonym)|uniprotkb:L-34 galactoside-binding lectin(gene name synonym)|uniprotkb:Laminin-binding protein(gene name synonym)|uniprotkb:Lectin L-29(gene name synonym)|uniprotkb:Mac-2 antigen(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509303|imex:IM-16925-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0001501"(skeletal system development)|go:"GO:0001772"(immunological synapse)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008380"(RNA splicing)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014064"(positive regulation of serotonin secretion)|go:"GO:0019863"(IgE binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0048030"(disaccharide binding)|go:"GO:0048245"(eosinophil chemotaxis)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0050785"(advanced glycation end-product receptor activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070232"(regulation of T cell apoptotic process)|go:"GO:0070492"(oligosaccharide binding)|go:"GO:0071674"(mononuclear cell migration)|go:"GO:0071677"(positive regulation of mononuclear cell migration)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0097386"(glial cell projection)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903769"(negative regulation of cell proliferation in bone marrow)|go:"GO:2000521"(negative regulation of immunological synapse formation)|go:"GO:2001189"(negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR015534(Galectin-3)|interpro:IPR044156|rcsb pdb:7DF6|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|dip:DIP-2152N|reactome:R-MMU-6798695 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:N2sijU2wqDkA5EeDJXVS4DGcTX810090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:290CB2DF0F0EB7A5|rigid:YE6eIYM0G+d7OHDDVnIFScXkeDQ false - sufficient binding region:13-484 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O08709 uniprotkb:Q9Z0P7 intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0 intact:EBI-3508336|uniprotkb:Q8C8B4|uniprotkb:Q99JG0|uniprotkb:Q9D521|uniprotkb:Q9JLU1|ensembl:ENSMUSP00000049109 psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym) psi-mi:sufu_mouse(display_long)|uniprotkb:Sufu(gene name)|psi-mi:Sufu(display_short) psi-mi:"MI:0018"(two hybrid) Paces-Fessy et al. (2004) pubmed:14611647|imex:IM-16925 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-3509415|imex:IM-16925-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249 refseq:NP_001020562.1|refseq:NP_056567.2|ensembl:ENSMUSG00000025231(gene)|ensembl:ENSMUST00000039922(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001843"(neural tube closure)|go:"GO:0001947"(heart looping)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0035904"(aorta development)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR007768(Suppressor of fused)|interpro:IPR016591(Suppressor of fused protein)|interpro:IPR020941|interpro:IPR024314|interpro:IPR037181|interpro:IPR038489|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5632684 - - - figure legend:Table 1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/02/08 2014/10/16 rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090 rogid:ACNnSTpoMKaIt3eDs21BhRmVvD810090 intact-crc:080858DA9DF44ECA|rigid:jePM2hZLyjt8u9DYqlO47xdJe7Y false - sufficient binding region:13-484 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)