#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15387	uniprotkb:P49446	intact:EBI-7511254|intact:MINT-8283237	intact:EBI-911699|uniprotkb:Q62134|uniprotkb:Q62444|uniprotkb:Q64496|uniprotkb:Q3U369|uniprotkb:Q60986|uniprotkb:Q61042|ensembl:ENSMUSP00000073616|ensembl:ENSMUSP00000147313|ensembl:ENSMUSP00000147957	psi-mi:kcnb1_rat(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:Delayed rectifier potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym)	psi-mi:ptpre_mouse(display_long)|uniprotkb:Ptpre(gene name)|psi-mi:Ptpre(display_short)|uniprotkb:Ptpe(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Tiran et al. (2003)	mint:MINT-8277706|pubmed:12615930|doi:10.1074/jbc.M212766200	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617181|mint:MINT-8284322	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027359|rcsb pdb:2R9R|rcsb pdb:4JTA|interpro:IPR000210(BTB/POZ-like)|interpro:IPR005821(Ion transport)|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|rcsb pdb:4JTD|rcsb pdb:3LNM|rgd:2954|rcsb pdb:4JTC|interpro:IPR011333(BTB/POZ fold)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|refseq:NP_037318.1|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|interpro:IPR028325|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|reactome:R-RNO-1296072|reactome:R-RNO-381676|mint:MINT-8284324(identity)	ensembl:ENSMUSG00000041836(gene)|ensembl:ENSMUST00000073961(transcript)|ensembl:ENSMUST00000210833(transcript)|ensembl:ENSMUST00000211140(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR029021|refseq:NP_035342.3|refseq:NP_001303607.1|refseq:NP_001303608.1|refseq:NP_001303609.1|refseq:NP_001303610.1|mint:MINT-8284325(identity)	-	comment:mint	-	comment:mint|figure legend:fig.2	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/10/26	2014/10/16	rogid:XskxHGYDpeOX7fADwIzU0n2gT4810116	rogid:/fwPNM0qa16BSImQvahLiLVAgsE10090	intact-crc:E47E4A445E73A186|rigid:r9Mg2HjrowVEWwXQ1F0BmBBq5U0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P15387	uniprotkb:P49446	intact:EBI-7511254|intact:MINT-8283237	intact:EBI-911699|uniprotkb:Q62134|uniprotkb:Q62444|uniprotkb:Q64496|uniprotkb:Q3U369|uniprotkb:Q60986|uniprotkb:Q61042|ensembl:ENSMUSP00000073616|ensembl:ENSMUSP00000147313|ensembl:ENSMUSP00000147957	psi-mi:kcnb1_rat(display_long)|uniprotkb:Kcnb1(gene name)|psi-mi:Kcnb1(display_short)|uniprotkb:Delayed rectifier potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv2.1(gene name synonym)	psi-mi:ptpre_mouse(display_long)|uniprotkb:Ptpre(gene name)|psi-mi:Ptpre(display_short)|uniprotkb:Ptpe(gene name synonym)	psi-mi:"MI:0019"(coimmunoprecipitation)	Tiran et al. (2003)	mint:MINT-8277706|pubmed:12615930|doi:10.1074/jbc.M212766200	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8617197|mint:MINT-8284331	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027359|rcsb pdb:2R9R|rcsb pdb:4JTA|interpro:IPR000210(BTB/POZ-like)|interpro:IPR005821(Ion transport)|interpro:IPR004350(Potassium channel, voltage dependent, Kv2.1)|rcsb pdb:4JTD|rcsb pdb:3LNM|rgd:2954|rcsb pdb:4JTC|interpro:IPR011333(BTB/POZ fold)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|refseq:NP_037318.1|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003973(Potassium channel, voltage dependent, Kv2)|interpro:IPR028325|go:"GO:0000149"(SNARE binding)|go:"GO:0001508"(action potential)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098900"(regulation of action potential)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:2000671"(regulation of motor neuron apoptotic process)|reactome:R-RNO-1296072|reactome:R-RNO-381676|mint:MINT-8284333(identity)	ensembl:ENSMUSG00000041836(gene)|ensembl:ENSMUST00000073961(transcript)|ensembl:ENSMUST00000210833(transcript)|ensembl:ENSMUST00000211140(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR016336(Receptor tyrosine-protein phosphatase, alpha/epsilon-type)|interpro:IPR029021|refseq:NP_035342.3|refseq:NP_001303607.1|refseq:NP_001303608.1|refseq:NP_001303609.1|refseq:NP_001303610.1|mint:MINT-8284334(identity)	-	comment:mint|comment:"Resulting Phenotypic qualities (properties)[PATO]: PATO:0002221 (increased phosphorylation)"	-	comment:mint|figure legend:fig.4	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2011/10/26	2014/10/16	rogid:XskxHGYDpeOX7fADwIzU0n2gT4810116	rogid:/fwPNM0qa16BSImQvahLiLVAgsE10090	intact-crc:8E8B849D8C776F88|rigid:r9Mg2HjrowVEWwXQ1F0BmBBq5U0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)