#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P50582	uniprotkb:P40377	intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep"	intact:EBI-783248|ensemblfungi:"SPBC4.04c.1:pep"	psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym)	psi-mi:mcm2_schpo(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:Cell division control protein 19(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short)|uniprotkb:cdc19(gene name synonym)|uniprotkb:nda1(gene name synonym)|uniprotkb:SPBC4.04c(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3648710|imex:IM-17298-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0495"(experimental role)	psi-mi:"MI:0495"(experimental role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation)	interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_595477.1|interpro:IPR008045(MCM protein 2)|reactome:R-SPO-176187|interpro:IPR031327|reactome:R-SPO-68962|reactome:R-SPO-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|ensemblfungi:SPBC4.04c(gene)|ensemblfungi:SPBC4.04c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949	-	-	-	figure legend:Fig. 1B and Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812	rogid:b9w/1QXwh2OswMQSi6nQDuxooNg284812	intact-crc:BDE5593027BEB742|rigid:CeHLCPvqKiBj5fgw2O11DJHnnLA	false	ha tag:c-c	flag tag:n-n|his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P29458	uniprotkb:O42709	intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym)	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3648815|imex:IM-17298-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	intact-crc:077DCD8A98CB1C7D|rigid:juQvFTMmco2DwR4TKq3yt9MUquk	false	-	his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29458	uniprotkb:P40377	intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0	intact:EBI-783248|ensemblfungi:"SPBC4.04c.1:pep"	psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym)	psi-mi:mcm2_schpo(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:Cell division control protein 19(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short)|uniprotkb:cdc19(gene name synonym)|uniprotkb:nda1(gene name synonym)|uniprotkb:SPBC4.04c(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3648815|imex:IM-17298-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_595477.1|interpro:IPR008045(MCM protein 2)|reactome:R-SPO-176187|interpro:IPR031327|reactome:R-SPO-68962|reactome:R-SPO-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|ensemblfungi:SPBC4.04c(gene)|ensemblfungi:SPBC4.04c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812	rogid:b9w/1QXwh2OswMQSi6nQDuxooNg284812	intact-crc:077DCD8A98CB1C7D|rigid:juQvFTMmco2DwR4TKq3yt9MUquk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29458	uniprotkb:P50582	intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0	intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep"	psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym)	psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3648815|imex:IM-17298-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation)	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812	rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812	intact-crc:077DCD8A98CB1C7D|rigid:juQvFTMmco2DwR4TKq3yt9MUquk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29458	uniprotkb:O42709	intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym)	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3890640|imex:IM-17298-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	intact-crc:90C756D3DEC33349|rigid:sOpHzLBpPvQcAASmtP6ed4B9bQ0	false	-	his tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P29458	uniprotkb:P40377	intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0	intact:EBI-783248|ensemblfungi:"SPBC4.04c.1:pep"	psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym)	psi-mi:mcm2_schpo(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:Cell division control protein 19(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short)|uniprotkb:cdc19(gene name synonym)|uniprotkb:nda1(gene name synonym)|uniprotkb:SPBC4.04c(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3890640|imex:IM-17298-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_595477.1|interpro:IPR008045(MCM protein 2)|reactome:R-SPO-176187|interpro:IPR031327|reactome:R-SPO-68962|reactome:R-SPO-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|ensemblfungi:SPBC4.04c(gene)|ensemblfungi:SPBC4.04c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812	rogid:b9w/1QXwh2OswMQSi6nQDuxooNg284812	intact-crc:90C756D3DEC33349|rigid:sOpHzLBpPvQcAASmtP6ed4B9bQ0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O42709	uniprotkb:P50582	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep"	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3648912|imex:IM-17298-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation)	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812	intact-crc:A67FCFFE1CC390D2|rigid:wiu9N3XRI68O8bRPHtz20+WMHhg	false	his tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P50582	uniprotkb:O42709	intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep"	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym)	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3648933|imex:IM-17298-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation)	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	intact-crc:29E050BE273EC029|rigid:YKN2osvt182MVGsh3gMYyJwvy1I	false	ha tag:c-c	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P50582	uniprotkb:P40377	intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep"	intact:EBI-783248|ensemblfungi:"SPBC4.04c.1:pep"	psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym)	psi-mi:mcm2_schpo(display_long)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)|uniprotkb:Cell division control protein 19(gene name synonym)|uniprotkb:mcm2(gene name)|psi-mi:mcm2(display_short)|uniprotkb:cdc19(gene name synonym)|uniprotkb:nda1(gene name synonym)|uniprotkb:SPBC4.04c(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3648933|imex:IM-17298-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation)	interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|refseq:NP_595477.1|interpro:IPR008045(MCM protein 2)|reactome:R-SPO-176187|interpro:IPR031327|reactome:R-SPO-68962|reactome:R-SPO-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|ensemblfungi:SPBC4.04c(gene)|ensemblfungi:SPBC4.04c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949	-	-	-	figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812	rogid:b9w/1QXwh2OswMQSi6nQDuxooNg284812	intact-crc:29E050BE273EC029|rigid:YKN2osvt182MVGsh3gMYyJwvy1I	false	ha tag:c-c	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O75001	uniprotkb:O42709	intact:EBI-913851|uniprotkb:P87302|ensemblfungi:"SPBC25D12.03c.1:pep"	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	psi-mi:mcm7_schpo(display_long)|uniprotkb:mcm7(gene name)|psi-mi:mcm7(display_short)|uniprotkb:SPBC25D12.03c(orf name)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym)	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3649076|imex:IM-17298-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|ensemblfungi:SPBC25D12.03c(gene)|ensemblfungi:SPBC25D12.03c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|reactome:R-SPO-68949|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_596545.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:S6CJrZlBu8+BXIFuuE0eTa4k8lM284812	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	intact-crc:359132A91040DB85|rigid:AlhAlYaRMxSjT2JAIWJv673K27s	false	his tag:c-c|flag tag:c-c	his tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O75001	uniprotkb:P49731	intact:EBI-913851|uniprotkb:P87302|ensemblfungi:"SPBC25D12.03c.1:pep"	intact:EBI-913838|uniprotkb:Q9P7R7|ensemblfungi:"SPBC211.04c.1:pep"	psi-mi:mcm7_schpo(display_long)|uniprotkb:mcm7(gene name)|psi-mi:mcm7(display_short)|uniprotkb:SPBC25D12.03c(orf name)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym)	psi-mi:mcm6_schpo(display_long)|uniprotkb:mcm6(gene name)|psi-mi:mcm6(display_short)|uniprotkb:mis5(gene name synonym)|uniprotkb:SPBC211.04c(orf name)|uniprotkb:Minichromosome maintenance protein 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3649076|imex:IM-17298-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|ensemblfungi:SPBC25D12.03c(gene)|ensemblfungi:SPBC25D12.03c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|reactome:R-SPO-68949|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_596545.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	interpro:IPR027925|ensemblfungi:SPBC211.04c(gene)|ensemblfungi:SPBC211.04c.1(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|go:"GO:1902975"(mitotic DNA replication initiation)|reactome:R-SPO-68949|refseq:NP_596614.1|interpro:IPR008049(MCM protein 6)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:S6CJrZlBu8+BXIFuuE0eTa4k8lM284812	rogid:xySiHOX6v3x7mxe4TxjWl6vOHLA284812	intact-crc:359132A91040DB85|rigid:AlhAlYaRMxSjT2JAIWJv673K27s	false	his tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O75001	uniprotkb:P29458	intact:EBI-913851|uniprotkb:P87302|ensemblfungi:"SPBC25D12.03c.1:pep"	intact:EBI-913806|uniprotkb:Q9P7K4|uniprotkb:Q9USM0	psi-mi:mcm7_schpo(display_long)|uniprotkb:mcm7(gene name)|psi-mi:mcm7(display_short)|uniprotkb:SPBC25D12.03c(orf name)|uniprotkb:Minichromosome maintenance protein 7(gene name synonym)	psi-mi:mcm4_schpo(display_long)|uniprotkb:mcm4(gene name)|psi-mi:mcm4(display_short)|uniprotkb:cdc21(gene name synonym)|uniprotkb:SPCC16A11.17(orf name)|uniprotkb:SPCC24B10.01(orf name)|uniprotkb:Minichromosome maintenance protein 4(gene name synonym)|uniprotkb:Cell division control protein 21(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3649076|imex:IM-17298-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR027925|ensemblfungi:SPBC25D12.03c(gene)|ensemblfungi:SPBC25D12.03c.1(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|reactome:R-SPO-68949|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|refseq:NP_596545.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0030875"(rDNA protrusion)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0097373"(MCM core complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|reactome:R-SPO-68949|interpro:IPR008047(MCM protein 4)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|reactome:R-SPO-69052|refseq:NP_588004.2|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:S6CJrZlBu8+BXIFuuE0eTa4k8lM284812	rogid:CIJriUICsfTJTJ0gT08sjo5nYjc284812	intact-crc:359132A91040DB85|rigid:AlhAlYaRMxSjT2JAIWJv673K27s	false	his tag:c-c|flag tag:c-c	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P50582	uniprotkb:O42709	intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep"	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym)	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3649215|imex:IM-17298-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation)	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	-	-	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	intact-crc:DD3ACD7650E6E196|rigid:UFMgB1Ap+1dbFaAwcTJV/+TNhtU	false	ha tag:c-c	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:P50582	uniprotkb:O59836	intact:EBI-908476|uniprotkb:O94678|ensemblfungi:"SPBC776.12c.1:pep"	intact:EBI-908382|ensemblfungi:"SPCC550.13.1:pep"	psi-mi:hsk1_schpo(display_long)|uniprotkb:hsk1(gene name)|psi-mi:hsk1(display_short)|uniprotkb:SPBC776.12c(orf name)|uniprotkb:Minichromosome maintenance protein kinase(gene name synonym)|uniprotkb:Cdc7-related kinase(gene name synonym)	psi-mi:him1_schpo(display_long)|uniprotkb:SPCC550.13(orf name)|uniprotkb:him1(gene name)|psi-mi:him1(display_short)|uniprotkb:dfp1(gene name synonym)|uniprotkb:rad35(gene name synonym)|uniprotkb:DNA repair protein rad35(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3649215|imex:IM-17298-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_596328.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC776.12c(gene)|ensemblfungi:SPBC776.12c.1(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010620"(negative regulation of transcription by transcription factor catabolism)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0048478"(replication fork protection)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902975"(mitotic DNA replication initiation)	refseq:NP_588105.1|interpro:IPR001357(BRCT)|interpro:IPR013939(Regulatory subunit Dfp1/Him1, central region)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|interpro:IPR036420|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPCC550.13(gene)|ensemblfungi:SPCC550.13.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0048478"(replication fork protection)|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|go:"GO:1903468"(positive regulation of DNA replication initiation)	-	-	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:vu2hPDUtV3VzgfiEdhiYtw5WUpU284812	rogid:jqgB/+ji7/8agWCnJgorOov7kmA284812	intact-crc:DD3ACD7650E6E196|rigid:UFMgB1Ap+1dbFaAwcTJV/+TNhtU	false	ha tag:c-c	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:O42709	uniprotkb:O59836	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	intact:EBI-908382|ensemblfungi:"SPCC550.13.1:pep"	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:him1_schpo(display_long)|uniprotkb:SPCC550.13(orf name)|uniprotkb:him1(gene name)|psi-mi:him1(display_short)|uniprotkb:dfp1(gene name synonym)|uniprotkb:rad35(gene name synonym)|uniprotkb:DNA repair protein rad35(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3649123|imex:IM-17298-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	refseq:NP_588105.1|interpro:IPR001357(BRCT)|interpro:IPR013939(Regulatory subunit Dfp1/Him1, central region)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|interpro:IPR036420|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPCC550.13(gene)|ensemblfungi:SPCC550.13.1(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031431"(Dbf4-dependent protein kinase complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044732"(mitotic spindle pole body)|go:"GO:0048478"(replication fork protection)|go:"GO:1901987"(regulation of cell cycle phase transition)|go:"GO:1903466"(regulation of mitotic DNA replication initiation)|go:"GO:1903468"(positive regulation of DNA replication initiation)	-	-	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	rogid:jqgB/+ji7/8agWCnJgorOov7kmA284812	intact-crc:C764DF45148223CB|rigid:f6pUaAOWOTsPdmxHIxx3NgJems4	false	-	flag tag:n-n	-	-	psi-mi:"MI:0833"(autoradiography)	psi-mi:"MI:0833"(autoradiography)
uniprotkb:O42709	uniprotkb:P41389	intact:EBI-1387246|ensemblfungi:"SPBC1347.10.1:pep"	intact:EBI-913821|uniprotkb:Q9UTF5	psi-mi:mcm10_schpo(display_long)|uniprotkb:mcm10(gene name)|psi-mi:mcm10(display_short)|uniprotkb:cdc23(gene name synonym)|uniprotkb:SPBC1347.10(orf name)|uniprotkb:Minichromosome maintenance protein 10(gene name synonym)|uniprotkb:Cdc23 protein(gene name synonym)	psi-mi:mcm5_schpo(display_long)|uniprotkb:mcm5(gene name)|psi-mi:mcm5(display_short)|uniprotkb:nda4(gene name synonym)|uniprotkb:SPAC1B2.05(orf name)|uniprotkb:SPAC3F10.01(orf name)|uniprotkb:Minichromosome maintenance protein 5(gene name synonym)|uniprotkb:Cell division control protein nda4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lee et al. (2003)	pubmed:12604790|imex:IM-17298	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-3649013|imex:IM-17298-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR040184|refseq:NP_596702.1|interpro:IPR015408(Zinc finger, Mcm10/DnaG-type)|reactome:R-SPO-68962|reactome:R-SPO-176187|ensemblfungi:SPBC1347.10(gene)|ensemblfungi:SPBC1347.10.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003896"(DNA primase activity)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1903934"(positive regulation of DNA primase activity)|go:"GO:1904931"(MCM complex binding)	interpro:IPR027925|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|reactome:R-SPO-68949|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0042555"(MCM complex)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR008048(MCM protein 5)|interpro:IPR018525|interpro:IPR001208(MCM)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR031327|reactome:R-SPO-68962|interpro:IPR027417|reactome:R-SPO-69052|interpro:IPR033762|interpro:IPR041562|reactome:R-SPO-68867|reactome:R-SPO-176187	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/02	2014/10/16	rogid:Wgb0hLMXCcdWiIMDh5hICrKQ5P0284812	rogid:ftcKM6HTmI6f2S6eqnZoMyyoVbc284812	intact-crc:E5E66B9AAED58B66|rigid:wS0DqnRFSaMnfLdZ/o95VlK5NFk	false	his tag:n-n	flag tag:n-n|his tag:n-n	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)