#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q94131	uniprotkb:O17695	intact:EBI-300501|uniprotkb:Q9XTT5|ensemblmetazoa:Y49E10.14a.1|ensemblmetazoa:Y49E10.14a.2|uniprotkb:E9P8A6	intact:EBI-318045|ensemblmetazoa:C53A5.3.1	psi-mi:pie1_caeel(display_long)|uniprotkb:pie-1(gene name)|psi-mi:pie-1(display_short)|uniprotkb:pic-1(gene name synonym)|uniprotkb:Y49E10.14(orf name)	psi-mi:hda1_caeel(display_long)|uniprotkb:hda-1(gene name)|psi-mi:hda-1(display_short)|uniprotkb:C53A5.3(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3832361|imex:IM-17183-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00004027(gene)|ensemblmetazoa:Y49E10.14a.1(transcript)|ensemblmetazoa:Y49E10.14a.2(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001709"(cell fate determination)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0043186"(P granule)|wormbase:Y49E10.14a|wormbase:Y49E10.14b|reactome:R-CEL-450385|refseq:NP_001255166.1|refseq:NP_001255167.1|dip:DIP-25777N	refseq:NP_506599.1|wormbase:C53A5.3|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1903854"(negative regulation of stress response to copper ion)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|ensemblmetazoa:C53A5.3.1(transcript)|ensemblmetazoa:WBGene00001834(gene)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0043073"(germ cell nucleus)|dip:DIP-26427N	-	-	-	figure legend:Fig 4A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2011/03/14	2014/10/16	rogid:QoSJof2b+46C+28R7yJtnNY9lc86239	rogid:muul0dZ9oQUpxzy9aG7qV1lNlrI6239	intact-crc:03DE1CC57C797559|rigid:btbiXHg91n5X9GJq7bh1VaZcOzE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q94131	uniprotkb:G5EBZ4	intact:EBI-300501|uniprotkb:Q9XTT5|ensemblmetazoa:Y49E10.14a.1|ensemblmetazoa:Y49E10.14a.2|uniprotkb:E9P8A6	intact:EBI-3831970|ensemblmetazoa:F26F12.7.1	psi-mi:pie1_caeel(display_long)|uniprotkb:pie-1(gene name)|psi-mi:pie-1(display_short)|uniprotkb:pic-1(gene name synonym)|uniprotkb:Y49E10.14(orf name)	psi-mi:le418_caeel(display_long)|uniprotkb:let-418(gene name)|psi-mi:let-418(display_short)|uniprotkb:Lethal protein 418(gene name synonym)|uniprotkb:evl-11(gene name synonym)|uniprotkb:F26F12.7(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3832361|imex:IM-17183-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00004027(gene)|ensemblmetazoa:Y49E10.14a.1(transcript)|ensemblmetazoa:Y49E10.14a.2(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001709"(cell fate determination)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0043186"(P granule)|wormbase:Y49E10.14a|wormbase:Y49E10.14b|reactome:R-CEL-450385|refseq:NP_001255166.1|refseq:NP_001255167.1|dip:DIP-25777N	reactome:R-CEL-4551638|uniprotkb:Q19815(uniprot-removed-ac)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|refseq:NP_504523.1|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR038718|wormbase:F26F12.7|interpro:IPR027417|ensemblmetazoa:F26F12.7.1(transcript)|ensemblmetazoa:WBGene00002637(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070615"|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|reactome:R-CEL-8943724|reactome:R-CEL-3214815|reactome:R-CEL-9031628	-	-	-	figure legend:Fig 4A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2011/03/14	2014/10/16	rogid:QoSJof2b+46C+28R7yJtnNY9lc86239	rogid:Vrxb02LEo+TNlLFx5ihY/NHc6rE6239	intact-crc:03DE1CC57C797559|rigid:btbiXHg91n5X9GJq7bh1VaZcOzE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q94131	uniprotkb:Q21502	intact:EBI-300501|uniprotkb:Q9XTT5|ensemblmetazoa:Y49E10.14a.1|ensemblmetazoa:Y49E10.14a.2|uniprotkb:E9P8A6	intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1	psi-mi:pie1_caeel(display_long)|uniprotkb:pie-1(gene name)|psi-mi:pie-1(display_short)|uniprotkb:pic-1(gene name synonym)|uniprotkb:Y49E10.14(orf name)	psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3832361|imex:IM-17183-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00004027(gene)|ensemblmetazoa:Y49E10.14a.1(transcript)|ensemblmetazoa:Y49E10.14a.2(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001709"(cell fate determination)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0043186"(P granule)|wormbase:Y49E10.14a|wormbase:Y49E10.14b|reactome:R-CEL-450385|refseq:NP_001255166.1|refseq:NP_001255167.1|dip:DIP-25777N	refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)	-	-	-	figure legend:Fig 4A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-embryo)|taxid:6239(Caenorhabditis elegans embryo)	-	2011/03/14	2014/10/16	rogid:QoSJof2b+46C+28R7yJtnNY9lc86239	rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239	intact-crc:03DE1CC57C797559|rigid:btbiXHg91n5X9GJq7bh1VaZcOzE	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q21502	uniprotkb:G5EBZ4	intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1	intact:EBI-3831970|ensemblmetazoa:F26F12.7.1	psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short)	psi-mi:le418_caeel(display_long)|uniprotkb:let-418(gene name)|psi-mi:let-418(display_short)|uniprotkb:Lethal protein 418(gene name synonym)|uniprotkb:evl-11(gene name synonym)|uniprotkb:F26F12.7(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3832564|imex:IM-17183-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)	reactome:R-CEL-4551638|uniprotkb:Q19815(uniprot-removed-ac)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|refseq:NP_504523.1|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR038718|wormbase:F26F12.7|interpro:IPR027417|ensemblmetazoa:F26F12.7.1(transcript)|ensemblmetazoa:WBGene00002637(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070615"|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|reactome:R-CEL-8943724|reactome:R-CEL-3214815|reactome:R-CEL-9031628	-	-	-	figure legend:Fig 4B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2011/03/14	2014/10/16	rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239	rogid:Vrxb02LEo+TNlLFx5ihY/NHc6rE6239	intact-crc:81391A5A7FD1FF12|rigid:fPQRrFGd+ZHX+vu08MxUddnnJ+4	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q21502	uniprotkb:O17695	intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1	intact:EBI-318045|ensemblmetazoa:C53A5.3.1	psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short)	psi-mi:hda1_caeel(display_long)|uniprotkb:hda-1(gene name)|psi-mi:hda-1(display_short)|uniprotkb:C53A5.3(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3832564|imex:IM-17183-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)	refseq:NP_506599.1|wormbase:C53A5.3|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1903854"(negative regulation of stress response to copper ion)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|ensemblmetazoa:C53A5.3.1(transcript)|ensemblmetazoa:WBGene00001834(gene)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0043073"(germ cell nucleus)|dip:DIP-26427N	-	-	-	figure legend:Fig 4B.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2011/03/14	2014/10/16	rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239	rogid:muul0dZ9oQUpxzy9aG7qV1lNlrI6239	intact-crc:81391A5A7FD1FF12|rigid:fPQRrFGd+ZHX+vu08MxUddnnJ+4	false	green fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q21502	uniprotkb:Q94131	intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1	intact:EBI-300501|uniprotkb:Q9XTT5|ensemblmetazoa:Y49E10.14a.1|ensemblmetazoa:Y49E10.14a.2|uniprotkb:E9P8A6	psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short)	psi-mi:pie1_caeel(display_long)|uniprotkb:pie-1(gene name)|psi-mi:pie-1(display_short)|uniprotkb:pic-1(gene name synonym)|uniprotkb:Y49E10.14(orf name)	psi-mi:"MI:0096"(pull down)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3832659|imex:IM-17183-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)	ensemblmetazoa:WBGene00004027(gene)|ensemblmetazoa:Y49E10.14a.1(transcript)|ensemblmetazoa:Y49E10.14a.2(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001709"(cell fate determination)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0043186"(P granule)|wormbase:Y49E10.14a|wormbase:Y49E10.14b|reactome:R-CEL-450385|refseq:NP_001255166.1|refseq:NP_001255167.1|dip:DIP-25777N	-	-	-	figure legend:Fig 4|comment:"The proline-rich domain of PIE-1 interacts primarily with the second and third Zn-fingers of MEP-1 (Figure 4E)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/03/14	2014/10/16	rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239	rogid:QoSJof2b+46C+28R7yJtnNY9lc86239	intact-crc:95F6730127519D58|rigid:+h8lOpSP0y+1HiHynENegPYjehM	false	binding-associated region:450..450-508..508|glutathione s tranferase tag:?-?|binding-associated region:545..545-690..690	ha tag:?-?|necessary binding region:240..240-268..268	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q94131	uniprotkb:Q21502	intact:EBI-300501|uniprotkb:Q9XTT5|ensemblmetazoa:Y49E10.14a.1|ensemblmetazoa:Y49E10.14a.2|uniprotkb:E9P8A6	intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1	psi-mi:pie1_caeel(display_long)|uniprotkb:pie-1(gene name)|psi-mi:pie-1(display_short)|uniprotkb:pic-1(gene name synonym)|uniprotkb:Y49E10.14(orf name)	psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short)	psi-mi:"MI:0018"(two hybrid)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3831842|imex:IM-17183-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00004027(gene)|ensemblmetazoa:Y49E10.14a.1(transcript)|ensemblmetazoa:Y49E10.14a.2(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001709"(cell fate determination)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0043186"(P granule)|wormbase:Y49E10.14a|wormbase:Y49E10.14b|reactome:R-CEL-450385|refseq:NP_001255166.1|refseq:NP_001255167.1|dip:DIP-25777N	refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2011/03/14	2014/10/16	rogid:QoSJof2b+46C+28R7yJtnNY9lc86239	rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239	intact-crc:A7E3E623D50A664C|rigid:+h8lOpSP0y+1HiHynENegPYjehM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:G5EBZ4	uniprotkb:Q21502	intact:EBI-3831970|ensemblmetazoa:F26F12.7.1	intact:EBI-319858|uniprotkb:Q95VF1|ensemblmetazoa:M04B2.1.1	psi-mi:le418_caeel(display_long)|uniprotkb:let-418(gene name)|psi-mi:let-418(display_short)|uniprotkb:Lethal protein 418(gene name synonym)|uniprotkb:evl-11(gene name synonym)|uniprotkb:F26F12.7(orf name)	psi-mi:mep1_caeel(display_long)|uniprotkb:M04B2.1(orf name)|uniprotkb:Nuclear zinc finger protein(gene name synonym)|uniprotkb:mep-1(gene name)|psi-mi:mep-1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3831929|imex:IM-17183-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-CEL-4551638|uniprotkb:Q19815(uniprot-removed-ac)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|refseq:NP_504523.1|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR038718|wormbase:F26F12.7|interpro:IPR027417|ensemblmetazoa:F26F12.7.1(transcript)|ensemblmetazoa:WBGene00002637(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0070615"|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|reactome:R-CEL-8943724|reactome:R-CEL-3214815|reactome:R-CEL-9031628	refseq:NP_502173.2|wormbase:M04B2.1|ensemblmetazoa:M04B2.1.1(transcript)|ensemblmetazoa:WBGene00003218(gene)|go:"GO:0002119"(nematode larval development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0007506"(gonadal mesoderm development)|go:"GO:0008406"(gonad development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0040025"(vulval development)|go:"GO:0040035"(hermaphrodite genitalia development)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048599"(oocyte development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)	-	-	-	figure legend:Fig 3A|caution:Figure 3A identifies a 280 kDa protein as a product of the gene let-418.  However the only let-418 protein in UniProt and WormBase has a molecular weight of ~209 kDa.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2011/03/14	2014/10/16	rogid:Vrxb02LEo+TNlLFx5ihY/NHc6rE6239	rogid:5BfQpmdZPLVYpnz8eRO3Ubzxqbg6239	intact-crc:FDD2155B887A69FB|rigid:LyZjfeZqUatW+9waoN1J28iSqVg	false	-	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:O17695	uniprotkb:Q94131	intact:EBI-318045|ensemblmetazoa:C53A5.3.1	intact:EBI-300501|uniprotkb:Q9XTT5|ensemblmetazoa:Y49E10.14a.1|ensemblmetazoa:Y49E10.14a.2|uniprotkb:E9P8A6	psi-mi:hda1_caeel(display_long)|uniprotkb:hda-1(gene name)|psi-mi:hda-1(display_short)|uniprotkb:C53A5.3(orf name)	psi-mi:pie1_caeel(display_long)|uniprotkb:pie-1(gene name)|psi-mi:pie-1(display_short)|uniprotkb:pic-1(gene name synonym)|uniprotkb:Y49E10.14(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3832428|imex:IM-17183-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_506599.1|wormbase:C53A5.3|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1903854"(negative regulation of stress response to copper ion)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|ensemblmetazoa:C53A5.3.1(transcript)|ensemblmetazoa:WBGene00001834(gene)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0043073"(germ cell nucleus)|dip:DIP-26427N	ensemblmetazoa:WBGene00004027(gene)|ensemblmetazoa:Y49E10.14a.1(transcript)|ensemblmetazoa:Y49E10.14a.2(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001709"(cell fate determination)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0043186"(P granule)|wormbase:Y49E10.14a|wormbase:Y49E10.14b|reactome:R-CEL-450385|refseq:NP_001255166.1|refseq:NP_001255167.1|dip:DIP-25777N	-	-	-	figure legend:Fig 4A|comment:"Identical immunoprecipitation assays on extracts prepared from mixed-stage animals where PIE-1 protein itself is undetectable (Figure 4A, lane 1) failed to recover detectable quantities of MEP-1 and LET-418 (Figure 4A, lane 3)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	-	2011/03/14	2014/10/16	rogid:muul0dZ9oQUpxzy9aG7qV1lNlrI6239	rogid:QoSJof2b+46C+28R7yJtnNY9lc86239	intact-crc:7AA27BC1BF7BDACD|rigid:N0JWDNe3rr+OClirHwR7duvoUB0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q94131	uniprotkb:O17695	intact:EBI-300501|uniprotkb:Q9XTT5|ensemblmetazoa:Y49E10.14a.1|ensemblmetazoa:Y49E10.14a.2|uniprotkb:E9P8A6	intact:EBI-318045|ensemblmetazoa:C53A5.3.1	psi-mi:pie1_caeel(display_long)|uniprotkb:pie-1(gene name)|psi-mi:pie-1(display_short)|uniprotkb:pic-1(gene name synonym)|uniprotkb:Y49E10.14(orf name)	psi-mi:hda1_caeel(display_long)|uniprotkb:hda-1(gene name)|psi-mi:hda-1(display_short)|uniprotkb:C53A5.3(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Unhavaithaya et al. (2002)	pubmed:12507426|imex:IM-17183	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3834089|imex:IM-17183-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:WBGene00004027(gene)|ensemblmetazoa:Y49E10.14a.1(transcript)|ensemblmetazoa:Y49E10.14a.2(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001709"(cell fate determination)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003677"(DNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0031064"(negative regulation of histone deacetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|go:"GO:0043186"(P granule)|wormbase:Y49E10.14a|wormbase:Y49E10.14b|reactome:R-CEL-450385|refseq:NP_001255166.1|refseq:NP_001255167.1|dip:DIP-25777N	refseq:NP_506599.1|wormbase:C53A5.3|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045138"(nematode male tail tip morphogenesis)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1903854"(negative regulation of stress response to copper ion)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|ensemblmetazoa:C53A5.3.1(transcript)|ensemblmetazoa:WBGene00001834(gene)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008406"(gonad development)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0040027"(negative regulation of vulval development)|go:"GO:0042001"(hermaphrodite somatic sex determination)|go:"GO:0043073"(germ cell nucleus)|dip:DIP-26427N	-	-	-	figure legend:Fig 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2011/03/14	2014/10/16	rogid:QoSJof2b+46C+28R7yJtnNY9lc86239	rogid:muul0dZ9oQUpxzy9aG7qV1lNlrI6239	intact-crc:73FD222D57EB0B5C|rigid:N0JWDNe3rr+OClirHwR7duvoUB0	false	necessary binding region:c-c|ha tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)