#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q08043	uniprotkb:P09467	intact:EBI-2880652|ensembl:ENSP00000426797|uniprotkb:Q4KKV2|uniprotkb:A6NP77	intact:EBI-712740|ensembl:ENSP00000364475|ensembl:ENSP00000408025|uniprotkb:O75571|uniprotkb:Q53F94|uniprotkb:Q96E46	psi-mi:actn3_human(display_long)|uniprotkb:ACTN3(gene name)|psi-mi:ACTN3(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 3(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:f16p1_human(display_long)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase 1(gene name synonym)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:FBP(gene name synonym)|uniprotkb:Liver FBPase(gene name synonym)	psi-mi:"MI:0401"(biochemical)	Gizak et al. (2003)	mint:MINT-8216728|pubmed:12507293	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8581318|mint:MINT-8216748	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051015"(actin filament binding)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904025"(positive regulation of glucose catabolic process to lactate via pyruvate)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000248746(gene)|ensembl:ENST00000513398(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0030018"(Z disc)|go:"GO:0031143"(pseudopodium)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0042802"(identical protein binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1TJT|rcsb pdb:1WKU|rcsb pdb:3LUE|reactome:R-HSA-373753|reactome:R-HSA-390522|refseq:NP_001245300.2|refseq:NP_001095.2|mint:MINT-8216751(identity)	ensembl:ENST00000375326(transcript)|ensembl:ENST00000415431(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0016208"(AMP binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0035690"|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071286"(cellular response to magnesium ion)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|mint:P09467|rcsb pdb:1FTA|rcsb pdb:2FHY|rcsb pdb:2FIE|rcsb pdb:2FIX|rcsb pdb:2JJK|rcsb pdb:2VT5|rcsb pdb:2WBB|rcsb pdb:2WBD|rcsb pdb:2Y5K|rcsb pdb:2Y5L|rcsb pdb:3A29|rcsb pdb:3KBZ|rcsb pdb:3KC0|ensembl:ENSG00000165140(gene)|rcsb pdb:3KC1|rcsb pdb:4MJO|rcsb pdb:5LDZ|rcsb pdb:5PZR|rcsb pdb:5PZS|rcsb pdb:5PZT|rcsb pdb:5PZU|rcsb pdb:5PZV|rcsb pdb:5PZW|rcsb pdb:5PZX|rcsb pdb:5PZY|rcsb pdb:5PZZ|rcsb pdb:5Q00|rcsb pdb:5Q01|rcsb pdb:5Q02|rcsb pdb:5Q03|rcsb pdb:5Q04|rcsb pdb:5Q05|rcsb pdb:5Q06|rcsb pdb:5Q07|rcsb pdb:5Q08|rcsb pdb:5Q09|rcsb pdb:5PZQ|rcsb pdb:5Q0A|rcsb pdb:5Q0B|rcsb pdb:6LS5|rcsb pdb:6LW2|rcsb pdb:7C9Q|rcsb pdb:7CVN|reactome:R-HSA-70263|refseq:NP_000498.2|refseq:NP_001121100.1|dip:DIP-46677N|mint:MINT-8216750(identity)	-	-	-	comment:mint|figure legend:f5 f6 f7|partial coverage:partial coverage	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2011/10/17	2014/10/16	rogid:ihTlyeKGYaTOZTmd5oP5FeFmo089606	rogid:DnrtyrU5WL/7ut1qWv7LndveJT89606	intact-crc:B866C5FF25BB5A79|rigid:E8MrA3LnbQzks2ltPh5n2T2po24	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)