#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P70338 uniprotkb:O54714 intact:EBI-3954754|uniprotkb:O09063 intact:EBI-927969|uniprotkb:Q80WF8|uniprotkb:Q8R598|ensembl:ENSMUSP00000069259 psi-mi:gfi1_mouse(display_long)|uniprotkb:Gfi1(gene name)|psi-mi:Gfi1(display_short)|uniprotkb:Gfi-1(gene name synonym)|uniprotkb:Growth factor independent protein 1(gene name synonym) psi-mi:pias3_mouse(display_long)|uniprotkb:Pias3(gene name)|psi-mi:Pias3(display_short)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Rodel et al. (2000) pubmed:11060035|mint:MINT-5213151 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4288647 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036236|interpro:IPR029840|refseq:NP_034408.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006534854.2|refseq:XP_006534855.1|refseq:XP_006534856.1|refseq:XP_006534857.1|refseq:XP_011247711.1 refseq:XP_006501456.1|refseq:NP_001159421.1|refseq:NP_061282.2|refseq:NP_666247.1|ensembl:ENSMUSG00000028101(gene)|ensembl:ENSMUST00000064900(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3232118|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4615885|reactome:R-MMU-4755510|reactome:R-MMU-5696395 - - - figure legend:1|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/21 2014/10/16 rogid:sH+bAKkVxMD068DivNKCcg9iK6410090 rogid:d8EvFm07//XoYpSn4EMJ8brV+gQ10090 intact-crc:0975E57B0F984515|rigid:uRYXlLy3tnhAJmJ8qRNFQZjO9rg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P70338 uniprotkb:O54714 intact:EBI-3954754|uniprotkb:O09063 intact:EBI-927969|uniprotkb:Q80WF8|uniprotkb:Q8R598|ensembl:ENSMUSP00000069259 psi-mi:gfi1_mouse(display_long)|uniprotkb:Gfi1(gene name)|psi-mi:Gfi1(display_short)|uniprotkb:Gfi-1(gene name synonym)|uniprotkb:Growth factor independent protein 1(gene name synonym) psi-mi:pias3_mouse(display_long)|uniprotkb:Pias3(gene name)|psi-mi:Pias3(display_short)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Rodel et al. (2000) pubmed:11060035|mint:MINT-5213151 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4288658 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036236|interpro:IPR029840|refseq:NP_034408.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006534854.2|refseq:XP_006534855.1|refseq:XP_006534856.1|refseq:XP_006534857.1|refseq:XP_011247711.1 refseq:XP_006501456.1|refseq:NP_001159421.1|refseq:NP_061282.2|refseq:NP_666247.1|ensembl:ENSMUSG00000028101(gene)|ensembl:ENSMUST00000064900(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3232118|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4615885|reactome:R-MMU-4755510|reactome:R-MMU-5696395 - - - figure legend:2|curation depth:mimix curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2011/06/21 2014/10/16 rogid:sH+bAKkVxMD068DivNKCcg9iK6410090 rogid:d8EvFm07//XoYpSn4EMJ8brV+gQ10090 intact-crc:04C428EF3E9F5A16|rigid:uRYXlLy3tnhAJmJ8qRNFQZjO9rg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P70338 uniprotkb:O54714 intact:EBI-3954754|uniprotkb:O09063 intact:EBI-927969|uniprotkb:Q80WF8|uniprotkb:Q8R598|ensembl:ENSMUSP00000069259 psi-mi:gfi1_mouse(display_long)|uniprotkb:Gfi1(gene name)|psi-mi:Gfi1(display_short)|uniprotkb:Gfi-1(gene name synonym)|uniprotkb:Growth factor independent protein 1(gene name synonym) psi-mi:pias3_mouse(display_long)|uniprotkb:Pias3(gene name)|psi-mi:Pias3(display_short)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:"MI:0096"(pull down) Rodel et al. (2000) pubmed:11060035|mint:MINT-5213151 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-4288671 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036236|interpro:IPR029840|refseq:NP_034408.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006534854.2|refseq:XP_006534855.1|refseq:XP_006534856.1|refseq:XP_006534857.1|refseq:XP_011247711.1 refseq:XP_006501456.1|refseq:NP_001159421.1|refseq:NP_061282.2|refseq:NP_666247.1|ensembl:ENSMUSG00000028101(gene)|ensembl:ENSMUST00000064900(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3232118|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4615885|reactome:R-MMU-4755510|reactome:R-MMU-5696395 - - - figure legend:3a|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/21 2014/10/16 rogid:sH+bAKkVxMD068DivNKCcg9iK6410090 rogid:d8EvFm07//XoYpSn4EMJ8brV+gQ10090 intact-crc:FD11361095A3879B|rigid:uRYXlLy3tnhAJmJ8qRNFQZjO9rg false - - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:P70338 uniprotkb:O54714 intact:EBI-3954754|uniprotkb:O09063 intact:EBI-927969|uniprotkb:Q80WF8|uniprotkb:Q8R598|ensembl:ENSMUSP00000069259 psi-mi:gfi1_mouse(display_long)|uniprotkb:Gfi1(gene name)|psi-mi:Gfi1(display_short)|uniprotkb:Gfi-1(gene name synonym)|uniprotkb:Growth factor independent protein 1(gene name synonym) psi-mi:pias3_mouse(display_long)|uniprotkb:Pias3(gene name)|psi-mi:Pias3(display_short)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:"MI:0096"(pull down) Rodel et al. (2000) pubmed:11060035|mint:MINT-5213151 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-4288682 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036236|interpro:IPR029840|refseq:NP_034408.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006534854.2|refseq:XP_006534855.1|refseq:XP_006534856.1|refseq:XP_006534857.1|refseq:XP_011247711.1 refseq:XP_006501456.1|refseq:NP_001159421.1|refseq:NP_061282.2|refseq:NP_666247.1|ensembl:ENSMUSG00000028101(gene)|ensembl:ENSMUST00000064900(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3232118|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4615885|reactome:R-MMU-4755510|reactome:R-MMU-5696395 - - - figure legend:3b|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/21 2014/10/16 rogid:sH+bAKkVxMD068DivNKCcg9iK6410090 rogid:d8EvFm07//XoYpSn4EMJ8brV+gQ10090 intact-crc:F952027E440EB072|rigid:uRYXlLy3tnhAJmJ8qRNFQZjO9rg false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P70338 uniprotkb:O54714 intact:EBI-3954754|uniprotkb:O09063 intact:EBI-927969|uniprotkb:Q80WF8|uniprotkb:Q8R598|ensembl:ENSMUSP00000069259 psi-mi:gfi1_mouse(display_long)|uniprotkb:Gfi1(gene name)|psi-mi:Gfi1(display_short)|uniprotkb:Gfi-1(gene name synonym)|uniprotkb:Growth factor independent protein 1(gene name synonym) psi-mi:pias3_mouse(display_long)|uniprotkb:Pias3(gene name)|psi-mi:Pias3(display_short)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:"MI:0096"(pull down) Rodel et al. (2000) pubmed:11060035|mint:MINT-5213151 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-4288686 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036236|interpro:IPR029840|refseq:NP_034408.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006534854.2|refseq:XP_006534855.1|refseq:XP_006534856.1|refseq:XP_006534857.1|refseq:XP_011247711.1 refseq:XP_006501456.1|refseq:NP_001159421.1|refseq:NP_061282.2|refseq:NP_666247.1|ensembl:ENSMUSG00000028101(gene)|ensembl:ENSMUST00000064900(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3232118|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4615885|reactome:R-MMU-4755510|reactome:R-MMU-5696395 - - - figure legend:3b|curation depth:mimix curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2011/06/21 2014/10/16 rogid:sH+bAKkVxMD068DivNKCcg9iK6410090 rogid:d8EvFm07//XoYpSn4EMJ8brV+gQ10090 intact-crc:D9BAAC7CE289F3C0|rigid:uRYXlLy3tnhAJmJ8qRNFQZjO9rg false - - - - psi-mi:"MI:0816"(molecular weight estimation by staining) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:Q9Y6X2 uniprotkb:Q99684 intact:EBI-2803703|uniprotkb:Q9UFI3|intact:EBI-28970301|ensembl:ENSP00000376765 intact:EBI-949368|ensembl:ENSP00000294702|ensembl:ENSP00000359357|ensembl:ENSP00000399719|uniprotkb:Q8N564 psi-mi:pias3_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:PIAS3(gene name)|psi-mi:PIAS3(display_short)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:gfi1_human(display_long)|uniprotkb:Growth factor independent protein 1(gene name synonym)|uniprotkb:Zinc finger protein 163(gene name synonym)|uniprotkb:GFI1(gene name)|psi-mi:GFI1(display_short)|uniprotkb:ZNF163(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Rodel et al. (2000) pubmed:11060035|mint:MINT-5213151 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-4288698 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000376765|ensembl:ENSG00000131788(gene)|ensembl:ENST00000393045(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:Q9Y6X2|rcsb pdb:4MVT|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4615885|reactome:R-HSA-4755510|reactome:R-HSA-5696395|go:"GO:0016925"(protein sumoylation)|refseq:NP_006090.2|dip:DIP-5969N ensembl:ENSG00000162676(gene)|ensembl:ENST00000294702(transcript)|ensembl:ENST00000370332(transcript)|ensembl:ENST00000427103(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010957"(negative regulation of vitamin D biosynthetic process)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR029840|interpro:IPR036236|reactome:R-HSA-9616222|refseq:NP_001120688.1|refseq:NP_005254.2|refseq:NP_001120687.1|dip:DIP-38452N|refseq:XP_011539547.1|refseq:XP_011539548.1|refseq:XP_005270806.1 - - - figure legend:4|curation depth:mimix curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2011/06/21 2014/10/16 rogid:uAxtGVgFcpm5yJL1rul8vVciHZA9606 rogid:BFND3tswCN4YNWrz8KZQeS0EZUw9606 intact-crc:73BB34B263B0EE7A|rigid:pyQnrhMS91GWeqrwR5ZFP2AhV2Q false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70338 uniprotkb:O54714 intact:EBI-3954754|uniprotkb:O09063 intact:EBI-927969|uniprotkb:Q80WF8|uniprotkb:Q8R598|ensembl:ENSMUSP00000069259 psi-mi:gfi1_mouse(display_long)|uniprotkb:Gfi1(gene name)|psi-mi:Gfi1(display_short)|uniprotkb:Gfi-1(gene name synonym)|uniprotkb:Growth factor independent protein 1(gene name synonym) psi-mi:pias3_mouse(display_long)|uniprotkb:Pias3(gene name)|psi-mi:Pias3(display_short)|uniprotkb:Protein inhibitor of activated STAT protein 3(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS3(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Rodel et al. (2000) pubmed:11060035|mint:MINT-5213151 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-4288709 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR036236|interpro:IPR029840|refseq:NP_034408.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007638"(mechanosensory behavior)|go:"GO:0009996"(negative regulation of cell fate specification)|go:"GO:0010956"(negative regulation of calcidiol 1-monooxygenase activity)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042660"(positive regulation of cell fate specification)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_006534854.2|refseq:XP_006534855.1|refseq:XP_006534856.1|refseq:XP_006534857.1|refseq:XP_011247711.1 refseq:XP_006501456.1|refseq:NP_001159421.1|refseq:NP_061282.2|refseq:NP_666247.1|ensembl:ENSMUSG00000028101(gene)|ensembl:ENSMUST00000064900(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0045202"(synapse)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0071847"(TNFSF11-mediated signaling pathway)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|reactome:R-MMU-3232118|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4615885|reactome:R-MMU-4755510|reactome:R-MMU-5696395 go:"GO:0005634"(nucleus) - - figure legend:5 and 6|curation depth:mimix curation taxid:10090(mouse-3t3)|taxid:10090(Mus musculus embryo cells) - 2011/06/21 2014/10/16 rogid:sH+bAKkVxMD068DivNKCcg9iK6410090 rogid:d8EvFm07//XoYpSn4EMJ8brV+gQ10090 intact-crc:CE36AC81E25FBAAA|rigid:uRYXlLy3tnhAJmJ8qRNFQZjO9rg false - - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)