#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P09581	uniprotkb:O89100	intact:EBI-6305373|ensembl:ENSMUSP00000025523|ensembl:ENSMUSP00000110923|uniprotkb:Q3U3P1|uniprotkb:Q9DBH9	intact:EBI-642151|ensembl:ENSMUSP00000046532|ensembl:ENSMUSP00000155681	psi-mi:csf1r_mouse(display_long)|uniprotkb:Csf1r(gene name)|psi-mi:Csf1r(display_short)|uniprotkb:Csfmr(gene name synonym)|uniprotkb:Fms(gene name synonym)|uniprotkb:CSF-1 receptor(gene name synonym)|uniprotkb:Proto-oncogene c-Fms(gene name synonym)	psi-mi:grap2_mouse(display_long)|uniprotkb:GADS protein(gene name synonym)|uniprotkb:Growth factor receptor-binding protein(gene name synonym)|uniprotkb:GRBLG(gene name synonym)|uniprotkb:GRB-2-like protein(gene name synonym)|uniprotkb:Hematopoietic cell-associated adaptor protein GrpL(gene name synonym)|uniprotkb:GRB-2-related monocytic adapter protein(gene name synonym)|uniprotkb:Adapter protein GRID(gene name synonym)|uniprotkb:Grap2(gene name)|psi-mi:Grap2(display_short)|uniprotkb:Gads(gene name synonym)|uniprotkb:Grb2l(gene name synonym)|uniprotkb:Grid(gene name synonym)|uniprotkb:Mona(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Bourette et al. (1998)	mint:MINT-6730992|pubmed:9857184	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8661673|mint:MINT-8034797	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-MMU-449836|rcsb pdb:4EXP|ensembl:ENSMUSG00000024621(gene)|ensembl:ENSMUST00000025523(transcript)|ensembl:ENSMUST00000115268(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005011"(macrophage colony-stimulating factor receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0014005"(microglia development)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032944"(regulation of mononuclear cell proliferation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0038145"(macrophage colony-stimulating factor signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990682"(CSF1-CSF1R complex)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR030658|interpro:IPR036179|rcsb pdb:3EJJ|dip:DIP-46415N|refseq:XP_006525647.1|refseq:XP_006525648.1|refseq:XP_006525649.1|refseq:NP_001032948.2|refseq:XP_017173299.1|mint:MINT-8034801(identity)|uniprotkb:P09581(original identifier)	refseq:NP_001276371.1|refseq:NP_034945.1|ensembl:ENSMUSG00000042351(gene)|ensembl:ENSMUST00000043149(transcript)|ensembl:ENSMUST00000229980(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035646|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:O89100|rcsb pdb:1H3H|rcsb pdb:1OEB|rcsb pdb:1R1P|rcsb pdb:1R1Q|rcsb pdb:1R1S|rcsb pdb:1UTI|rcsb pdb:2D0N|rcsb pdb:2W10|reactome:R-MMU-1433557|reactome:R-MMU-202433|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-389356|reactome:R-MMU-9607240|dip:DIP-41343N|mint:MINT-8034798(identity)|uniprotkb:O89100(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:jWzzruMZt6wnD2QFpQ4/aov3vlU10090	rogid:mHMapg+wLVtfZ6IQ2rAGoVeyEHQ10090	intact-crc:55E53C60CD3E4BDB|rigid:YlCpR8Gh27nggYTndzyHg2t7hyU	false	phosphorylated residue:697-697(MINT-8034806)|binding-associated region:690-703(MINT-8034804)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O89100	uniprotkb:P09581	intact:EBI-642151|ensembl:ENSMUSP00000046532|ensembl:ENSMUSP00000155681	intact:EBI-6305373|ensembl:ENSMUSP00000025523|ensembl:ENSMUSP00000110923|uniprotkb:Q3U3P1|uniprotkb:Q9DBH9	psi-mi:grap2_mouse(display_long)|uniprotkb:GADS protein(gene name synonym)|uniprotkb:Growth factor receptor-binding protein(gene name synonym)|uniprotkb:GRBLG(gene name synonym)|uniprotkb:GRB-2-like protein(gene name synonym)|uniprotkb:Hematopoietic cell-associated adaptor protein GrpL(gene name synonym)|uniprotkb:GRB-2-related monocytic adapter protein(gene name synonym)|uniprotkb:Adapter protein GRID(gene name synonym)|uniprotkb:Grap2(gene name)|psi-mi:Grap2(display_short)|uniprotkb:Gads(gene name synonym)|uniprotkb:Grb2l(gene name synonym)|uniprotkb:Grid(gene name synonym)|uniprotkb:Mona(gene name synonym)	psi-mi:csf1r_mouse(display_long)|uniprotkb:Csf1r(gene name)|psi-mi:Csf1r(display_short)|uniprotkb:Csfmr(gene name synonym)|uniprotkb:Fms(gene name synonym)|uniprotkb:CSF-1 receptor(gene name synonym)|uniprotkb:Proto-oncogene c-Fms(gene name synonym)	psi-mi:"MI:0096"(pull down)	Bourette et al. (1998)	mint:MINT-6730992|pubmed:9857184	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8661728|mint:MINT-8034812	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276371.1|refseq:NP_034945.1|ensembl:ENSMUSG00000042351(gene)|ensembl:ENSMUST00000043149(transcript)|ensembl:ENSMUST00000229980(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035646|interpro:IPR036028|interpro:IPR036860|interpro:IPR043539|mint:O89100|rcsb pdb:1H3H|rcsb pdb:1OEB|rcsb pdb:1R1P|rcsb pdb:1R1Q|rcsb pdb:1R1S|rcsb pdb:1UTI|rcsb pdb:2D0N|rcsb pdb:2W10|reactome:R-MMU-1433557|reactome:R-MMU-202433|reactome:R-MMU-2424491|reactome:R-MMU-2871796|reactome:R-MMU-2871809|reactome:R-MMU-389356|reactome:R-MMU-9607240|dip:DIP-41343N|mint:MINT-8034813(identity)|uniprotkb:O89100(original identifier)	reactome:R-MMU-449836|rcsb pdb:4EXP|ensembl:ENSMUSG00000024621(gene)|ensembl:ENSMUST00000025523(transcript)|ensembl:ENSMUST00000115268(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005011"(macrophage colony-stimulating factor receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0014005"(microglia development)|go:"GO:0016020"(membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021879"(forebrain neuron differentiation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032944"(regulation of mononuclear cell proliferation)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0036006"(cellular response to macrophage colony-stimulating factor stimulus)|go:"GO:0038145"(macrophage colony-stimulating factor signaling pathway)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990682"(CSF1-CSF1R complex)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001824(Receptor tyrosine kinase, class III, conserved site)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR030658|interpro:IPR036179|rcsb pdb:3EJJ|dip:DIP-46415N|refseq:XP_006525647.1|refseq:XP_006525648.1|refseq:XP_006525649.1|refseq:NP_001032948.2|refseq:XP_017173299.1|mint:MINT-8034816(identity)|uniprotkb:P09581(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:mHMapg+wLVtfZ6IQ2rAGoVeyEHQ10090	rogid:jWzzruMZt6wnD2QFpQ4/aov3vlU10090	intact-crc:E4969B9CBFB898CF|rigid:YlCpR8Gh27nggYTndzyHg2t7hyU	false	-	binding-associated region:690-703(MINT-8034819)|phosphorylated residue:697-697(MINT-8034821)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)