#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q62689	uniprotkb:P25095	intact:EBI-8656708|ensembl:ENSRNOP00000071877|intact:UNK-5463530	intact:EBI-764979|uniprotkb:Q9QVS5|ensembl:ENSRNOP00000034687	psi-mi:jak2_rat(display_long)|uniprotkb:Jak2(gene name)|psi-mi:Jak2(display_short)|uniprotkb:Janus kinase 2(gene name synonym)	psi-mi:agtra_rat(display_long)|uniprotkb:Angiotensin II type-1A receptor(gene name synonym)|uniprotkb:Agtr1(gene name)|psi-mi:Agtr1(display_short)|uniprotkb:Agtr1a(gene name synonym)|uniprotkb:At1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marrero et al. (1998)	mint:MINT-6730981|pubmed:9814969	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8656789|mint:MINT-8029417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|ensembl:ENSRNOG00000059968(gene)|ensembl:ENSRNOT00000087011(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000791"(euchromatin)|go:"GO:0001774"(microglial cell activation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005131"(growth hormone receptor binding)|go:"GO:0005143"(interleukin-12 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007260"(tyrosine phosphorylation of STAT protein)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010572"(positive regulation of platelet activation)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0012505"(endomembrane system)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0034050"(programmed cell death induced by symbiont)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031702"(type 1 angiotensin receptor binding)|go:"GO:0031959"(mineralocorticoid receptor signaling pathway)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|rgd:2939|refseq:NP_113702.1|interpro:IPR041155|interpro:IPR041381|reactome:R-RNO-1059683|reactome:R-RNO-110056|reactome:R-RNO-112411|reactome:R-RNO-1170546|reactome:R-RNO-1433557|reactome:R-RNO-512988|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-6785807|reactome:R-RNO-6788467|reactome:R-RNO-69231|reactome:R-RNO-877300|reactome:R-RNO-877312|reactome:R-RNO-8854691|reactome:R-RNO-8984722|reactome:R-RNO-9020591|reactome:R-RNO-9020933|reactome:R-RNO-9020956|reactome:R-RNO-9027276|reactome:R-RNO-9027284|interpro:IPR041046|reactome:R-RNO-912526|reactome:R-RNO-9674555|reactome:R-RNO-9705462|reactome:R-RNO-982772|reactome:R-RNO-983231|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0035401"("histone kinase activity (H3-Y41 specific)")|go:"GO:0035409"(histone H3-Y41 phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0036016"(cellular response to interleukin-3)|go:"GO:0038065"(collagen-activated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050867"(positive regulation of cell activation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0060399"(positive regulation of growth hormone receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061180"(mammary gland epithelium development)|go:"GO:0070671"(response to interleukin-12)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097296"(activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016251(Tyrosine-protein kinase, Jak/Tyk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR019749|interpro:IPR020635|interpro:IPR020693|interpro:IPR035588|interpro:IPR035589|interpro:IPR035860|interpro:IPR035963|interpro:IPR036860|interpro:IPR037838|go:"GO:0098794"(postsynapse)|dip:DIP-491N|mint:MINT-8029418(identity)|uniprotkb:Q62689(original identifier)	rgd:2070|refseq:NP_112247.2|refseq:XP_008769816.1|refseq:XP_006253944.1|ensembl:ENSRNOG00000018346(gene)|ensembl:ENSRNOT00000038532(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001596"(angiotensin type I receptor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002001"(renin secretion into blood stream)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0002035"(brain renin-angiotensin system)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006885"(regulation of pH)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0012505"(endomembrane system)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031968"(organelle outer membrane)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000190(AT1 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P25095|rcsb pdb:2AC6|rcsb pdb:2AH3|reactome:R-RNO-375276|reactome:R-RNO-416476|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042756"(drinking behavior)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0042310"(vasoconstriction)|mint:MINT-8029421(identity)|uniprotkb:P25095(original identifier)	-	function:Tyrosine kinase of the non-receptor type, involved in interleukin-3 and probably interleukin-23 signal transduction|comment:mint|comment:homomint	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:nfye5y/rvyIgq8d08J8G1vvW0VY10116	rogid:IBt+94S4gpjhzcKvbWNtv+8Xuqs10116	intact-crc:4554A5F30FBB053D|rigid:IwUVO1a+nZ/6X5ucpceeXPY4Neg	false	-	phosphorylated residue:319-319(MINT-8029426)|binding-associated region:312-325(MINT-8029424)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06124	uniprotkb:P25095	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	intact:EBI-764979|uniprotkb:Q9QVS5|ensembl:ENSRNOP00000034687	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:agtra_rat(display_long)|uniprotkb:Angiotensin II type-1A receptor(gene name synonym)|uniprotkb:Agtr1(gene name)|psi-mi:Agtr1(display_short)|uniprotkb:Agtr1a(gene name synonym)|uniprotkb:At1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Marrero et al. (1998)	mint:MINT-6730981|pubmed:9814969	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8656807|mint:MINT-8029428	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-8029429(identity)|uniprotkb:Q06124(original identifier)	rgd:2070|refseq:NP_112247.2|refseq:XP_008769816.1|refseq:XP_006253944.1|ensembl:ENSRNOG00000018346(gene)|ensembl:ENSRNOT00000038532(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001596"(angiotensin type I receptor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001822"(kidney development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001991"(regulation of systemic arterial blood pressure by circulatory renin-angiotensin)|go:"GO:0002001"(renin secretion into blood stream)|go:"GO:0002018"(renin-angiotensin regulation of aldosterone production)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0002035"(brain renin-angiotensin system)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004945"(angiotensin type II receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006885"(regulation of pH)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009651"(response to salt stress)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0012505"(endomembrane system)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031968"(organelle outer membrane)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000190(AT1 angiotensin II receptor)|interpro:IPR000248(Angiotensin II receptor)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P25095|rcsb pdb:2AC6|rcsb pdb:2AH3|reactome:R-RNO-375276|reactome:R-RNO-416476|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042756"(drinking behavior)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0055037"(recycling endosome)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0086097"(phospholipase C-activating angiotensin-activated signaling pathway)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0042310"(vasoconstriction)|mint:MINT-8029432(identity)|uniprotkb:P25095(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2020/01/07	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	rogid:IBt+94S4gpjhzcKvbWNtv+8Xuqs10116	intact-crc:97231061BCE5D20D|rigid:Kao0J+LrZ/gHcNdPQ1AXR8MDp90	false	-	phosphorylated residue:319-319(MINT-8029437)|binding-associated region:312-325(MINT-8029435)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)