#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q23862 uniprotkb:O76187 intact:EBI-2118748|uniprotkb:Q54U41|ensemblprotists:EAL66784 intact:EBI-2889579|ensemblprotists:EAL63007|uniprotkb:Q54IE6 psi-mi:race_dicdi(display_long)|uniprotkb:racE(gene name)|psi-mi:racE(display_short)|uniprotkb:DDB_G0280975(orf name) psi-mi:dara_dicdi(display_long)|uniprotkb:darA(gene name)|psi-mi:darA(display_short)|uniprotkb:Armadillo-like protein A(gene name synonym)|uniprotkb:DDB_G0288771(orf name) psi-mi:"MI:0096"(pull down) Vithalani et al. (1998) pubmed:9802899|imex:IM-20488 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2889593|imex:IM-20488-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0280975|ensemblprotists:DDB_G0280975(gene)|ensemblprotists:EAL66784(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0019954"(asexual reproduction)|go:"GO:0030587"(sorocarp development)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061118"(regulation of positive chemotaxis to cAMP)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|go:"GO:0007015"(actin filament organization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|refseq:XP_640935.1 ensemblprotists:DDB_G0288771(gene)|ensemblprotists:EAL63007(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016477"(cell migration)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040144|refseq:XP_636531.1|dictybase:DDB_G0288771 - - - figure legend:Fig. 1, Fig.3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/12 2014/10/16 rogid:LWrI4jmYLba5/roU6sc20r1m0A044689 rogid:LsqYEnJgo9facQj6uLiMhk/KbLY44689 intact-crc:11F78C35CA259382|rigid:r4jliWbmlWEZd6Q2dgy0mcT8a14 false glutathione s tranferase tag:?-? identified peptide:20-33|identified peptide:62-79|identified peptide:235-256 - - psi-mi:"MI:0433"(partial identification of protein sequence) psi-mi:"MI:0433"(partial identification of protein sequence) uniprotkb:Q23862 uniprotkb:O76187 intact:EBI-2118748|uniprotkb:Q54U41|ensemblprotists:EAL66784 intact:EBI-2889579|ensemblprotists:EAL63007|uniprotkb:Q54IE6 psi-mi:race_dicdi(display_long)|uniprotkb:racE(gene name)|psi-mi:racE(display_short)|uniprotkb:DDB_G0280975(orf name) psi-mi:dara_dicdi(display_long)|uniprotkb:darA(gene name)|psi-mi:darA(display_short)|uniprotkb:Armadillo-like protein A(gene name synonym)|uniprotkb:DDB_G0288771(orf name) psi-mi:"MI:0096"(pull down) Vithalani et al. (1998) pubmed:9802899|imex:IM-20488 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2905881|imex:IM-20488-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dictybase:DDB_G0280975|ensemblprotists:DDB_G0280975(gene)|ensemblprotists:EAL66784(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005811"(lipid droplet)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0019954"(asexual reproduction)|go:"GO:0030587"(sorocarp development)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031254"(cell trailing edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043327"(chemotaxis to cAMP)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061118"(regulation of positive chemotaxis to cAMP)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:1904515"(positive regulation of TORC2 signaling)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|go:"GO:0007015"(actin filament organization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|refseq:XP_640935.1 ensemblprotists:DDB_G0288771(gene)|ensemblprotists:EAL63007(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016477"(cell migration)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040144|refseq:XP_636531.1|dictybase:DDB_G0288771 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/12 2014/10/16 rogid:LWrI4jmYLba5/roU6sc20r1m0A044689 rogid:LsqYEnJgo9facQj6uLiMhk/KbLY44689 intact-crc:BFC0B81047410C7D|rigid:r4jliWbmlWEZd6Q2dgy0mcT8a14 false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:O76187 uniprotkb:P34149 intact:EBI-2889579|ensemblprotists:EAL63007|uniprotkb:Q54IE6 intact:EBI-2118726|uniprotkb:Q54BN9|ensemblprotists:EAL60575 psi-mi:dara_dicdi(display_long)|uniprotkb:darA(gene name)|psi-mi:darA(display_short)|uniprotkb:Armadillo-like protein A(gene name synonym)|uniprotkb:DDB_G0288771(orf name) psi-mi:racc_dicdi(display_long)|uniprotkb:racC(gene name)|psi-mi:racC(display_short)|uniprotkb:DDB_G0293526(orf name) psi-mi:"MI:0096"(pull down) Vithalani et al. (1998) pubmed:9802899|imex:IM-20488 taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2905888|imex:IM-20488-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblprotists:DDB_G0288771(gene)|ensemblprotists:EAL63007(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016477"(cell migration)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040144|refseq:XP_636531.1|dictybase:DDB_G0288771 dictybase:DDB_G0293526|ensemblprotists:DDB_G0293526(gene)|ensemblprotists:EAL60575(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006935"(chemotaxis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:1901610"(positive regulation of vesicle transport along microtubule)|go:"GO:1903669"(positive regulation of chemorepellent activity)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-DDI-9013404|reactome:R-DDI-9013407|reactome:R-DDI-9013418|reactome:R-DDI-9013420|reactome:R-DDI-9013422|reactome:R-DDI-9013424|reactome:R-DDI-9706019|refseq:XP_628990.1 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/12 2014/10/16 rogid:LsqYEnJgo9facQj6uLiMhk/KbLY44689 rogid:42oGCZt+b9OZG5xwaYTlPVK9v5E44689 intact-crc:61FD0D4980D87361|rigid:/PDdmdJqy2sHxp7Njx8iJg5aJc8 false - glutathione s tranferase tag:?-? - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P60953 uniprotkb:O76187 intact:EBI-81752|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q7L8R5|uniprotkb:Q9UDI2|ensembl:ENSP00000341072|ensembl:ENSP00000383118|ensembl:ENSP00000497733|ensembl:ENSP00000499457|ensembl:ENSP00000499612 intact:EBI-2889579|ensemblprotists:EAL63007|uniprotkb:Q54IE6 psi-mi:cdc42_human(display_long)|uniprotkb:CDC42(gene name)|psi-mi:CDC42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:dara_dicdi(display_long)|uniprotkb:darA(gene name)|psi-mi:darA(display_short)|uniprotkb:Armadillo-like protein A(gene name synonym)|uniprotkb:DDB_G0288771(orf name) psi-mi:"MI:0096"(pull down) Vithalani et al. (1998) pubmed:9802899|imex:IM-20488 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2905895|imex:IM-20488-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001034891.1|refseq:NP_001782.1|refseq:NP_426359.1|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0005886"(plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031996"(thioesterase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|ensembl:ENSG00000070831(gene)|ensembl:ENST00000344548(transcript)|ensembl:ENST00000400259(transcript)|ensembl:ENST00000648594(transcript)|ensembl:ENST00000656825(transcript)|ensembl:ENST00000662562(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60953|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0048664"(neuron fate determination)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|dip:DIP-31097N|reactome:R-HSA-983231|rcsb pdb:1AJE|rcsb pdb:1AM4|rcsb pdb:1AN0|rcsb pdb:1CEE|rcsb pdb:1CF4|rcsb pdb:1DOA|rcsb pdb:1E0A|rcsb pdb:1EES|rcsb pdb:1GRN|rcsb pdb:1GZS|rcsb pdb:1KI1|rcsb pdb:1KZ7|rcsb pdb:1KZG|rcsb pdb:1NF3|rcsb pdb:2ASE|rcsb pdb:2DFK|rcsb pdb:2KB0|rcsb pdb:2NGR|rcsb pdb:2ODB|rcsb pdb:2QRZ|rcsb pdb:2WM9|rcsb pdb:2WMN|rcsb pdb:2WMO|rcsb pdb:3GCG|rcsb pdb:3QBV|rcsb pdb:3VHL|rcsb pdb:4DID|rcsb pdb:4ITR|rcsb pdb:4JS0|rcsb pdb:4YC7|rcsb pdb:4YDH|rcsb pdb:5CJP|rcsb pdb:5FI1|rcsb pdb:5HZK|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:6AJ4|rcsb pdb:6AJL|rcsb pdb:6SIU|rcsb pdb:6SUP|rcsb pdb:6TKY|rcsb pdb:6TKZ|reactome:R-HSA-114604|reactome:R-HSA-182971|reactome:R-HSA-2029482|reactome:R-HSA-389359|reactome:R-HSA-3928662|reactome:R-HSA-418885|reactome:R-HSA-428543|reactome:R-HSA-4420097|reactome:R-HSA-525793|reactome:R-HSA-5625970|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-8964616|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|rcsb pdb:1A4R|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9664422 ensemblprotists:DDB_G0288771(gene)|ensemblprotists:EAL63007(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016477"(cell migration)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040144|refseq:XP_636531.1|dictybase:DDB_G0288771 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/12 2014/10/16 rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU9606 rogid:LsqYEnJgo9facQj6uLiMhk/KbLY44689 intact-crc:90C8A5B60C95DA52|rigid:uIHC7Zflp7RpLMR/Dm+ePorAkvY false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot) uniprotkb:P62826 uniprotkb:O76187 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 intact:EBI-2889579|ensemblprotists:EAL63007|uniprotkb:Q54IE6 psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:dara_dicdi(display_long)|uniprotkb:darA(gene name)|psi-mi:darA(display_short)|uniprotkb:Armadillo-like protein A(gene name synonym)|uniprotkb:DDB_G0288771(orf name) psi-mi:"MI:0096"(pull down) Vithalani et al. (1998) pubmed:9802899|imex:IM-20488 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:44689(dicdi)|taxid:44689("Dictyostelium discoideum (Slime mold)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2905901|imex:IM-20488-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 ensemblprotists:DDB_G0288771(gene)|ensemblprotists:EAL63007(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0016477"(cell migration)|go:"GO:0031152"(aggregation involved in sorocarp development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040144|refseq:XP_636531.1|dictybase:DDB_G0288771 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/07/12 2014/10/16 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rogid:LsqYEnJgo9facQj6uLiMhk/KbLY44689 intact-crc:12C41C7C4A86BB4A|rigid:JFmlWLwezJmMh9TlzAsC0+mLmQY false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0086"(polyclonal antibody western blot) psi-mi:"MI:0086"(polyclonal antibody western blot)