#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9NSE2 uniprotkb:P14753 intact:EBI-617866|uniprotkb:Q9NS38|uniprotkb:Q9Y5R1|uniprotkb:B2R9N1|uniprotkb:G5E9R1|ensembl:ENSP00000294173 intact:EBI-617901|ensembl:ENSMUSP00000006397|uniprotkb:Q63852 psi-mi:cish_human(display_long)|uniprotkb:CIS-1(gene name synonym)|uniprotkb:Suppressor of cytokine signaling(gene name synonym)|uniprotkb:Protein G18(gene name synonym)|uniprotkb:CISH(gene name)|psi-mi:CISH(display_short)|uniprotkb:G18(gene name synonym) psi-mi:epor_mouse(display_long)|uniprotkb:Epor(gene name)|psi-mi:Epor(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Verdier et al. (1998) pubmed:9774439|mint:MINT-6730969 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8686175|mint:MINT-8037118 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037456.5|refseq:NP_659508.1|refseq:XP_011531631.1|ensembl:ENSG00000114737(gene)|ensembl:ENST00000348721(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028425|interpro:IPR035887|interpro:IPR036036|interpro:IPR036860|mint:Q9NSE2|reactome:R-HSA-1266695|reactome:R-HSA-8951664|reactome:R-HSA-982772|mint:MINT-8037119(identity)|uniprotkb:Q9NSE2(original identifier) reactome:R-MMU-9027276|reactome:R-MMU-9027284|rcsb pdb:2MXB|ensembl:ENSMUSG00000006235(gene)|ensembl:ENSMUST00000006397(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0004900"(erythropoietin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046697"(decidualization)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR009167(Erythropoietin receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR036116|mint:P14753|refseq:NP_034279.3|dip:DIP-657N|mint:MINT-8037122(identity)|uniprotkb:P14753(original identifier) - - - comment:homomint|comment:mint|partial coverage:partial coverage taxid:-3(unknown)|taxid:-3(Unknown) - 2010/09/29 2014/10/16 rogid:NnfVh2fsTGqxfR+nBBPR4xtdHZg9606 rogid:UIMmftITb7Wp1qd5cqrkS9XFR3Q10090 intact-crc:7EC3CF49D613A4E7|rigid:UZBYSZ52qYyRfo0095Z0FBkSH+0 false - phosphorylated residue:425-425(MINT-8037127)|binding-associated region:418-431(MINT-8037125) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)