#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16658 uniprotkb:Q04675 intact:EBI-16953|uniprotkb:D6VYA5|ensemblfungi:YLR105C intact:EBI-16817|uniprotkb:D6VZN3|ensemblfungi:YMR059W psi-mi:sen2_yeast(display_long)|uniprotkb:SEN2(gene name)|psi-mi:SEN2(display_short)|uniprotkb:YLR105C(locus name)|uniprotkb:L8004.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN2(gene name synonym)|uniprotkb:Splicing endonuclease protein 2(gene name synonym) psi-mi:sen15_yeast(display_long)|uniprotkb:SEN15(gene name)|psi-mi:SEN15(display_short)|uniprotkb:YMR059W(locus name)|uniprotkb:YM9796.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN15(gene name synonym)|uniprotkb:Splicing endonuclease of 15 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610230|imex:IM-20446-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013206.1|sgd:S000004095|ensemblfungi:YLR105C(gene)|ensemblfungi:YLR105C_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|go:"GO:0098787"(mRNA cleavage involved in mRNA processing)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR016589(tRNA-splicing endonuclease, SEN2 subunit)|interpro:IPR036167|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|dip:DIP-4821N ensemblfungi:YMR059W(gene)|ensemblfungi:YMR059W_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR018593|interpro:IPR036167|interpro:IPR042777|go:"GO:0012505"(endomembrane system)|refseq:NP_013775.2|sgd:S000004663|dip:DIP-5802N - crc64:B5A9C7F865538F5C crc64:17DF8B5F3824DF82 figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:XiJMNtoLsKIsnU+7ALV5uB1Re28559292 rogid:nqcJdyU2tF2vB60hstHtQfyQiPc559292 intact-crc:FDFC61C71EE35E30|rigid:VpBZiawnqP+daRl34czxTpTFluI false his tag:?-?|flag tag:?-? - - - psi-mi:"MI:0433"(partial identification of protein sequence) psi-mi:"MI:0433"(partial identification of protein sequence) uniprotkb:P16658 uniprotkb:Q02825 intact:EBI-16953|uniprotkb:D6VYA5|ensemblfungi:YLR105C intact:EBI-16829|uniprotkb:D6W3T4|ensemblfungi:YPL083C psi-mi:sen2_yeast(display_long)|uniprotkb:SEN2(gene name)|psi-mi:SEN2(display_short)|uniprotkb:YLR105C(locus name)|uniprotkb:L8004.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN2(gene name synonym)|uniprotkb:Splicing endonuclease protein 2(gene name synonym) psi-mi:sen54_yeast(display_long)|uniprotkb:SEN54(gene name)|psi-mi:SEN54(display_short)|uniprotkb:YPL083C(locus name)|uniprotkb:LPF3C(orf name)|uniprotkb:tRNA-intron endonuclease SEN54(gene name synonym)|uniprotkb:Splicing endonuclease of 54 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610230|imex:IM-20446-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013206.1|sgd:S000004095|ensemblfungi:YLR105C(gene)|ensemblfungi:YLR105C_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|go:"GO:0098787"(mRNA cleavage involved in mRNA processing)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR016589(tRNA-splicing endonuclease, SEN2 subunit)|interpro:IPR036167|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|dip:DIP-4821N ensemblfungi:YPL083C(gene)|ensemblfungi:YPL083C_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR024336|interpro:IPR024337|refseq:NP_015242.1|sgd:S000006004|dip:DIP-4452N|mint:Q02825 - crc64:B5A9C7F865538F5C - figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:XiJMNtoLsKIsnU+7ALV5uB1Re28559292 rogid:B3HByPP2gu+B5283ZPc8RZ/YAFw559292 intact-crc:FDFC61C71EE35E30|rigid:VpBZiawnqP+daRl34czxTpTFluI false his tag:?-?|flag tag:?-? - - - psi-mi:"MI:0433"(partial identification of protein sequence) psi-mi:"MI:0433"(partial identification of protein sequence) uniprotkb:P16658 uniprotkb:P39707 intact:EBI-16953|uniprotkb:D6VYA5|ensemblfungi:YLR105C intact:EBI-16825|ensemblfungi:YAR008W|uniprotkb:D6VPM0 psi-mi:sen2_yeast(display_long)|uniprotkb:SEN2(gene name)|psi-mi:SEN2(display_short)|uniprotkb:YLR105C(locus name)|uniprotkb:L8004.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN2(gene name synonym)|uniprotkb:Splicing endonuclease protein 2(gene name synonym) psi-mi:sen34_yeast(display_long)|uniprotkb:SEN34(gene name)|psi-mi:SEN34(display_short)|uniprotkb:YAR008W(locus name)|uniprotkb:FUN4(orf name)|uniprotkb:tRNA-intron endonuclease SEN34(gene name synonym)|uniprotkb:Splicing endonuclease of 34 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610230|imex:IM-20446-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013206.1|sgd:S000004095|ensemblfungi:YLR105C(gene)|ensemblfungi:YLR105C_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|go:"GO:0098787"(mRNA cleavage involved in mRNA processing)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR016589(tRNA-splicing endonuclease, SEN2 subunit)|interpro:IPR036167|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|dip:DIP-4821N ensemblfungi:YAR008W(gene)|ensemblfungi:YAR008W_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR016690(tRNA-splicing endonuclease, SEN34 subunit)|interpro:IPR036167|refseq:NP_009405.1|sgd:S000000066|dip:DIP-3794N - crc64:B5A9C7F865538F5C crc64:CCEA2A30209AB03F figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:XiJMNtoLsKIsnU+7ALV5uB1Re28559292 rogid:hXs9Fo+r+haAbZ6AZK8T/R0WBgw559292 intact-crc:FDFC61C71EE35E30|rigid:VpBZiawnqP+daRl34czxTpTFluI false his tag:?-?|flag tag:?-? - - - psi-mi:"MI:0433"(partial identification of protein sequence) psi-mi:"MI:0433"(partial identification of protein sequence) uniprotkb:P16658 uniprotkb:P39707 intact:EBI-16953|uniprotkb:D6VYA5|ensemblfungi:YLR105C intact:EBI-16825|ensemblfungi:YAR008W|uniprotkb:D6VPM0 psi-mi:sen2_yeast(display_long)|uniprotkb:SEN2(gene name)|psi-mi:SEN2(display_short)|uniprotkb:YLR105C(locus name)|uniprotkb:L8004.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN2(gene name synonym)|uniprotkb:Splicing endonuclease protein 2(gene name synonym) psi-mi:sen34_yeast(display_long)|uniprotkb:SEN34(gene name)|psi-mi:SEN34(display_short)|uniprotkb:YAR008W(locus name)|uniprotkb:FUN4(orf name)|uniprotkb:tRNA-intron endonuclease SEN34(gene name synonym)|uniprotkb:Splicing endonuclease of 34 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610250|imex:IM-20446-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013206.1|sgd:S000004095|ensemblfungi:YLR105C(gene)|ensemblfungi:YLR105C_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|go:"GO:0098787"(mRNA cleavage involved in mRNA processing)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR016589(tRNA-splicing endonuclease, SEN2 subunit)|interpro:IPR036167|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|dip:DIP-4821N ensemblfungi:YAR008W(gene)|ensemblfungi:YAR008W_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR016690(tRNA-splicing endonuclease, SEN34 subunit)|interpro:IPR036167|refseq:NP_009405.1|sgd:S000000066|dip:DIP-3794N - crc64:B5A9C7F865538F5C crc64:CCEA2A30209AB03F figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:XiJMNtoLsKIsnU+7ALV5uB1Re28559292 rogid:hXs9Fo+r+haAbZ6AZK8T/R0WBgw559292 intact-crc:624E9E2BAB801B5C|rigid:VpBZiawnqP+daRl34czxTpTFluI false his tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P16658 uniprotkb:Q02825 intact:EBI-16953|uniprotkb:D6VYA5|ensemblfungi:YLR105C intact:EBI-16829|uniprotkb:D6W3T4|ensemblfungi:YPL083C psi-mi:sen2_yeast(display_long)|uniprotkb:SEN2(gene name)|psi-mi:SEN2(display_short)|uniprotkb:YLR105C(locus name)|uniprotkb:L8004.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN2(gene name synonym)|uniprotkb:Splicing endonuclease protein 2(gene name synonym) psi-mi:sen54_yeast(display_long)|uniprotkb:SEN54(gene name)|psi-mi:SEN54(display_short)|uniprotkb:YPL083C(locus name)|uniprotkb:LPF3C(orf name)|uniprotkb:tRNA-intron endonuclease SEN54(gene name synonym)|uniprotkb:Splicing endonuclease of 54 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610250|imex:IM-20446-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013206.1|sgd:S000004095|ensemblfungi:YLR105C(gene)|ensemblfungi:YLR105C_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|go:"GO:0098787"(mRNA cleavage involved in mRNA processing)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR016589(tRNA-splicing endonuclease, SEN2 subunit)|interpro:IPR036167|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|dip:DIP-4821N ensemblfungi:YPL083C(gene)|ensemblfungi:YPL083C_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR024336|interpro:IPR024337|refseq:NP_015242.1|sgd:S000006004|dip:DIP-4452N|mint:Q02825 - crc64:B5A9C7F865538F5C - figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:XiJMNtoLsKIsnU+7ALV5uB1Re28559292 rogid:B3HByPP2gu+B5283ZPc8RZ/YAFw559292 intact-crc:624E9E2BAB801B5C|rigid:VpBZiawnqP+daRl34czxTpTFluI false his tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P16658 uniprotkb:Q04675 intact:EBI-16953|uniprotkb:D6VYA5|ensemblfungi:YLR105C intact:EBI-16817|uniprotkb:D6VZN3|ensemblfungi:YMR059W psi-mi:sen2_yeast(display_long)|uniprotkb:SEN2(gene name)|psi-mi:SEN2(display_short)|uniprotkb:YLR105C(locus name)|uniprotkb:L8004.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN2(gene name synonym)|uniprotkb:Splicing endonuclease protein 2(gene name synonym) psi-mi:sen15_yeast(display_long)|uniprotkb:SEN15(gene name)|psi-mi:SEN15(display_short)|uniprotkb:YMR059W(locus name)|uniprotkb:YM9796.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN15(gene name synonym)|uniprotkb:Splicing endonuclease of 15 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610250|imex:IM-20446-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013206.1|sgd:S000004095|ensemblfungi:YLR105C(gene)|ensemblfungi:YLR105C_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|go:"GO:0098787"(mRNA cleavage involved in mRNA processing)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR016589(tRNA-splicing endonuclease, SEN2 subunit)|interpro:IPR036167|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|dip:DIP-4821N ensemblfungi:YMR059W(gene)|ensemblfungi:YMR059W_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR018593|interpro:IPR036167|interpro:IPR042777|go:"GO:0012505"(endomembrane system)|refseq:NP_013775.2|sgd:S000004663|dip:DIP-5802N - crc64:B5A9C7F865538F5C crc64:17DF8B5F3824DF82 figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:XiJMNtoLsKIsnU+7ALV5uB1Re28559292 rogid:nqcJdyU2tF2vB60hstHtQfyQiPc559292 intact-crc:624E9E2BAB801B5C|rigid:VpBZiawnqP+daRl34czxTpTFluI false his tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P39707 uniprotkb:Q04675 intact:EBI-16825|ensemblfungi:YAR008W|uniprotkb:D6VPM0 intact:EBI-16817|uniprotkb:D6VZN3|ensemblfungi:YMR059W psi-mi:sen34_yeast(display_long)|uniprotkb:SEN34(gene name)|psi-mi:SEN34(display_short)|uniprotkb:YAR008W(locus name)|uniprotkb:FUN4(orf name)|uniprotkb:tRNA-intron endonuclease SEN34(gene name synonym)|uniprotkb:Splicing endonuclease of 34 kDa(gene name synonym) psi-mi:sen15_yeast(display_long)|uniprotkb:SEN15(gene name)|psi-mi:SEN15(display_short)|uniprotkb:YMR059W(locus name)|uniprotkb:YM9796.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN15(gene name synonym)|uniprotkb:Splicing endonuclease of 15 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610268|imex:IM-20446-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YAR008W(gene)|ensemblfungi:YAR008W_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR016690(tRNA-splicing endonuclease, SEN34 subunit)|interpro:IPR036167|refseq:NP_009405.1|sgd:S000000066|dip:DIP-3794N ensemblfungi:YMR059W(gene)|ensemblfungi:YMR059W_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR018593|interpro:IPR036167|interpro:IPR042777|go:"GO:0012505"(endomembrane system)|refseq:NP_013775.2|sgd:S000004663|dip:DIP-5802N - crc64:CCEA2A30209AB03F crc64:17DF8B5F3824DF82 figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:hXs9Fo+r+haAbZ6AZK8T/R0WBgw559292 rogid:nqcJdyU2tF2vB60hstHtQfyQiPc559292 intact-crc:2BD078FB14304615|rigid:DrJ41ToQ0zjdvbXiVvuYlCz11Cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39707 uniprotkb:Q04675 intact:EBI-16825|ensemblfungi:YAR008W|uniprotkb:D6VPM0 intact:EBI-16817|uniprotkb:D6VZN3|ensemblfungi:YMR059W psi-mi:sen34_yeast(display_long)|uniprotkb:SEN34(gene name)|psi-mi:SEN34(display_short)|uniprotkb:YAR008W(locus name)|uniprotkb:FUN4(orf name)|uniprotkb:tRNA-intron endonuclease SEN34(gene name synonym)|uniprotkb:Splicing endonuclease of 34 kDa(gene name synonym) psi-mi:sen15_yeast(display_long)|uniprotkb:SEN15(gene name)|psi-mi:SEN15(display_short)|uniprotkb:YMR059W(locus name)|uniprotkb:YM9796.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN15(gene name synonym)|uniprotkb:Splicing endonuclease of 15 kDa(gene name synonym) psi-mi:"MI:0018"(two hybrid) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610273|imex:IM-20446-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YAR008W(gene)|ensemblfungi:YAR008W_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR016690(tRNA-splicing endonuclease, SEN34 subunit)|interpro:IPR036167|refseq:NP_009405.1|sgd:S000000066|dip:DIP-3794N ensemblfungi:YMR059W(gene)|ensemblfungi:YMR059W_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR018593|interpro:IPR036167|interpro:IPR042777|go:"GO:0012505"(endomembrane system)|refseq:NP_013775.2|sgd:S000004663|dip:DIP-5802N - crc64:CCEA2A30209AB03F crc64:17DF8B5F3824DF82 figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:hXs9Fo+r+haAbZ6AZK8T/R0WBgw559292 rogid:nqcJdyU2tF2vB60hstHtQfyQiPc559292 intact-crc:D3917FDC2EF4671A|rigid:DrJ41ToQ0zjdvbXiVvuYlCz11Cc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q02825 uniprotkb:P16658 intact:EBI-16829|uniprotkb:D6W3T4|ensemblfungi:YPL083C intact:EBI-16953|uniprotkb:D6VYA5|ensemblfungi:YLR105C psi-mi:sen54_yeast(display_long)|uniprotkb:SEN54(gene name)|psi-mi:SEN54(display_short)|uniprotkb:YPL083C(locus name)|uniprotkb:LPF3C(orf name)|uniprotkb:tRNA-intron endonuclease SEN54(gene name synonym)|uniprotkb:Splicing endonuclease of 54 kDa(gene name synonym) psi-mi:sen2_yeast(display_long)|uniprotkb:SEN2(gene name)|psi-mi:SEN2(display_short)|uniprotkb:YLR105C(locus name)|uniprotkb:L8004.12(orf name)|uniprotkb:tRNA-intron endonuclease SEN2(gene name synonym)|uniprotkb:Splicing endonuclease protein 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2610278|imex:IM-20446-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL083C(gene)|ensemblfungi:YPL083C_mRNA(transcript)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR024336|interpro:IPR024337|refseq:NP_015242.1|sgd:S000006004|dip:DIP-4452N|mint:Q02825 refseq:NP_013206.1|sgd:S000004095|ensemblfungi:YLR105C(gene)|ensemblfungi:YLR105C_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|go:"GO:0098787"(mRNA cleavage involved in mRNA processing)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR016589(tRNA-splicing endonuclease, SEN2 subunit)|interpro:IPR036167|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|dip:DIP-4821N - - crc64:B5A9C7F865538F5C figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2010/03/11 2014/10/16 rogid:B3HByPP2gu+B5283ZPc8RZ/YAFw559292 rogid:XiJMNtoLsKIsnU+7ALV5uB1Re28559292 intact-crc:E42FBE8DC66E44E6|rigid:gI0dIO2gQssq/P0qoLszUPNN5D0 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-11705578 uniprotkb:P39707 rnacentral:URS00000890D0_559292 intact:EBI-16825|ensemblfungi:YAR008W|uniprotkb:D6VPM0 psi-mi:trna phe gaa precursor(display_short)|psi-mi:EBI-11705578(display_long) psi-mi:sen34_yeast(display_long)|uniprotkb:SEN34(gene name)|psi-mi:SEN34(display_short)|uniprotkb:YAR008W(locus name)|uniprotkb:FUN4(orf name)|uniprotkb:tRNA-intron endonuclease SEN34(gene name synonym)|uniprotkb:Splicing endonuclease of 34 kDa(gene name synonym) psi-mi:"MI:0990"(cleavage assay) Trotta et al. (1997) pubmed:9200603|imex:IM-20446 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-12560206|imex:IM-20446-6 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0325"(transfer rna) psi-mi:"MI:0326"(protein) - ensemblfungi:YAR008W(gene)|ensemblfungi:YAR008W_mRNA(transcript)|go:"GO:0000213"(tRNA-intron endonuclease activity)|go:"GO:0000214"(tRNA-intron endonuclease complex)|go:"GO:0000379"(tRNA-type intron splice site recognition and cleavage)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016829"(lyase activity)|interpro:IPR006676(tRNA-intron endonuclease)|interpro:IPR006677(tRNA intron endonuclease, catalytic domain-like)|interpro:IPR011856(Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)|interpro:IPR016690(tRNA-splicing endonuclease, SEN34 subunit)|interpro:IPR036167|refseq:NP_009405.1|sgd:S000000066|dip:DIP-3794N - - crc64:CCEA2A30209AB03F figure legend:Fig 6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/03/11 2016/10/13 - rogid:hXs9Fo+r+haAbZ6AZK8T/R0WBgw559292 - false 32p radiolabel:?-? tandem tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)