#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P15367	uniprotkb:P46965	intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name)	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2614852|imex:IM-18954-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	intact-crc:99B28104E7CF905F|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15367	uniprotkb:Q04969	intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name)	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2614852|imex:IM-18954-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	intact-crc:99B28104E7CF905F|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15367	uniprotkb:Q12133	intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W	intact:EBI-17829|uniprotkb:D6VY67|ensemblfungi:YLR066W	psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name)	psi-mi:spc3_yeast(display_long)|uniprotkb:SPC3(gene name)|psi-mi:SPC3(display_short)|uniprotkb:YLR066W(locus name)|uniprotkb:L2186(orf name)|uniprotkb:Microsomal signal peptidase subunit 3(gene name synonym)	psi-mi:"MI:0004"(affinity chromatography technology)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2614852|imex:IM-18954-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367	sgd:S000004056|refseq:NP_013167.1|ensemblfungi:YLR066W(gene)|ensemblfungi:YLR066W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|dip:DIP-5083N|mint:Q12133	-	-	-	figure legend:Fig. 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292	rogid:Yo9d2WsA1GUlNLc0oSPZhYk+fvs559292	intact-crc:99B28104E7CF905F|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46965	uniprotkb:P15367	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2614877|imex:IM-18954-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N	refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367	-	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292	intact-crc:E0099DEC44FCA0B1|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46965	uniprotkb:Q04969	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2614877|imex:IM-18954-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)	-	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	intact-crc:E0099DEC44FCA0B1|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P46965	uniprotkb:Q12133	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	intact:EBI-17829|uniprotkb:D6VY67|ensemblfungi:YLR066W	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:spc3_yeast(display_long)|uniprotkb:SPC3(gene name)|psi-mi:SPC3(display_short)|uniprotkb:YLR066W(locus name)|uniprotkb:L2186(orf name)|uniprotkb:Microsomal signal peptidase subunit 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2614877|imex:IM-18954-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N	sgd:S000004056|refseq:NP_013167.1|ensemblfungi:YLR066W(gene)|ensemblfungi:YLR066W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|dip:DIP-5083N|mint:Q12133	-	-	-	figure legend:Fig. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	rogid:Yo9d2WsA1GUlNLc0oSPZhYk+fvs559292	intact-crc:E0099DEC44FCA0B1|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P15367	uniprotkb:P46965	intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W	intact:EBI-17823|uniprotkb:D6VWI6|ensemblfungi:YJR010C-A	psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name)	psi-mi:spc1_yeast(display_long)|uniprotkb:SPC1(gene name)|psi-mi:SPC1(display_short)|uniprotkb:YJR010C-A(locus name)|uniprotkb:YJR010BW(orf name)|uniprotkb:Microsomal signal peptidase subunit 1(gene name synonym)	psi-mi:"MI:0401"(biochemical)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2653852|imex:IM-18954-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367	refseq:NP_012544.1|sgd:S000003770|ensemblfungi:YJR010C-A(gene)|ensemblfungi:YJR010C-A_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR009542(Microsomal signal peptidase 12 kDa subunit)|interpro:IPR037713|mint:P46965|dip:DIP-2770N	-	-	-	figure legend:Fig. 2B|comment:Identity of SPC3 was confirmed by Edman digestion.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292	rogid:kchUi3mkadvzweVkrWO3QkbbHew559292	intact-crc:82367F780FB04E1F|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0823"(predetermined feature)	psi-mi:"MI:0823"(predetermined feature)
uniprotkb:P15367	uniprotkb:Q04969	intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W	intact:EBI-27827|uniprotkb:D6VZB9|ensemblfungi:YML055W	psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name)	psi-mi:spc2_yeast(display_long)|uniprotkb:YML055W(locus name)|uniprotkb:YM9958.07(orf name)|uniprotkb:SPC2(gene name)|psi-mi:SPC2(display_short)|uniprotkb:SPY1(gene name synonym)|uniprotkb:Microsomal signal peptidase subunit 2(gene name synonym)	psi-mi:"MI:0401"(biochemical)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2653852|imex:IM-18954-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367	refseq:NP_013657.1|sgd:S000004519|dip:DIP-4540N|mint:Q04969|ensemblfungi:YML055W(gene)|ensemblfungi:YML055W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|go:"GO:0120236"(negative regulation of posttranslational protein targeting to membrane, translocation)|interpro:IPR009582(Microsomal signal peptidase 25 kDa subunit)	-	-	-	figure legend:Fig. 2B|comment:Identity of SPC3 was confirmed by Edman digestion.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292	rogid:ZXf9rPA3/ryPnDqI4JGp0VMNMe4559292	intact-crc:82367F780FB04E1F|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0823"(predetermined feature)	psi-mi:"MI:0823"(predetermined feature)
uniprotkb:P15367	uniprotkb:Q12133	intact:EBI-16513|uniprotkb:D6VVV3|ensemblfungi:YIR022W	intact:EBI-17829|uniprotkb:D6VY67|ensemblfungi:YLR066W	psi-mi:sec11_yeast(display_long)|uniprotkb:SEC11(gene name)|psi-mi:SEC11(display_short)|uniprotkb:Signal peptidase I(gene name synonym)|uniprotkb:Secretory protein 11(gene name synonym)|uniprotkb:YIR022W(locus name)	psi-mi:spc3_yeast(display_long)|uniprotkb:SPC3(gene name)|psi-mi:SPC3(display_short)|uniprotkb:YLR066W(locus name)|uniprotkb:L2186(orf name)|uniprotkb:Microsomal signal peptidase subunit 3(gene name synonym)	psi-mi:"MI:0401"(biochemical)	Meyer et al. (1997)	pubmed:9148931|imex:IM-18954	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2653852|imex:IM-18954-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012288.1|sgd:S000001461|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0008233"(peptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR001733(Peptidase S26B, eukaryotic signal peptidase)|interpro:IPR015927(Peptidase S24, S26A, S26B and S26C)|interpro:IPR019756|interpro:IPR019758|interpro:IPR027245|interpro:IPR036286|ensemblfungi:YIR022W(gene)|ensemblfungi:YIR022W_mRNA(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-5667N|mint:P15367	sgd:S000004056|refseq:NP_013167.1|ensemblfungi:YLR066W(gene)|ensemblfungi:YLR066W_mRNA(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005787"(signal peptidase complex)|go:"GO:0006465"(signal peptide processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR007653(Signal peptidase 22 kDa subunit)|dip:DIP-5083N|mint:Q12133	-	-	-	figure legend:Fig. 2B|comment:Identity of SPC3 was confirmed by Edman digestion.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2010/03/12	2014/10/16	rogid:t+RiGy79Pv7EbHywbjkd4BMyJwk559292	rogid:Yo9d2WsA1GUlNLc0oSPZhYk+fvs559292	intact-crc:82367F780FB04E1F|rigid:NGxbgjou32FyKyU3f2HIFLby2CU	false	-	-	-	-	psi-mi:"MI:0823"(predetermined feature)	psi-mi:"MI:0823"(predetermined feature)