#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43628	uniprotkb:P29350	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-78260|intact:EBI-28977917|ensembl:ENSP00000326010|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680828|mint:MINT-8027372	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8027376(identity)|uniprotkb:P43628(original identifier)	ensembl:ENSG00000111679(gene)|ensembl:ENST00000318974(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|rcsb pdb:3PS5|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|ensembl:ENSP00000326010|ensembl:ENST00000399448|ensembl:ENSP00000382376|ensembl:ENST00000456013|ensembl:ENSP00000391592|refseq:XP_011519290.1|dip:DIP-31002N|mint:MINT-8027373(identity)|uniprotkb:P29350(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:44F93156E71EC152|rigid:/fjALg7ovK9PWw+K3ScOWsHLU8U	false	phosphorylated residue:303-303(MINT-8027381)|binding-associated region:296-309(MINT-8027379)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43628	uniprotkb:Q06124	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680877|mint:MINT-8027402	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8027406(identity)|uniprotkb:P43628(original identifier)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-8027403(identity)|uniprotkb:Q06124(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2020/01/07	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:21D087204316B343|rigid:zBRPhGBmKxMlQ3DqFcrJpcaajrE	false	phosphorylated residue:303-303(MINT-8027411)|binding-associated region:296-309(MINT-8027409)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20963	uniprotkb:P43403	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	intact:EBI-1211276|uniprotkb:A6NFP4|uniprotkb:Q6PIA4|uniprotkb:Q8IXD6|uniprotkb:Q9UBS6|ensembl:ENSP00000264972	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:zap70_human(display_long)|uniprotkb:ZAP70(gene name)|psi-mi:ZAP70(display_short)|uniprotkb:SRK(gene name synonym)|uniprotkb:Syk-related tyrosine kinase(gene name synonym)|uniprotkb:70 kDa zeta-chain associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680931|mint:MINT-8032973	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|mint:MINT-8032977(identity)|uniprotkb:P20963(original identifier)	refseq:NP_001070.2|refseq:NP_997402.1|dip:DIP-38781N|ensembl:ENSG00000115085(gene)|ensembl:ENST00000264972(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042113"(B cell activation)|go:"GO:0043366"(beta selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070489"(T cell aggregation)|go:"GO:0072678"(T cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43403|rcsb pdb:1FBV|rcsb pdb:1M61|rcsb pdb:1U59|rcsb pdb:2CBL|rcsb pdb:2OQ1|rcsb pdb:2OZO|rcsb pdb:2Y1N|rcsb pdb:3ZNI|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4K2R|rcsb pdb:4XZ0|rcsb pdb:4XZ1|rcsb pdb:5O76|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-9013407|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042110"(T cell activation)|mint:MINT-8032974(identity)|uniprotkb:P43403(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	rogid:21kVb/nxY2BBZPBNVwWba+qUOgc9606	intact-crc:88F8C3220D8EC57A|rigid:Pru20NE1fLdUUpLl9QVBqW5hXEc	false	phosphorylated residue:83-83(MINT-8032982)|binding-associated region:76-89(MINT-8032980)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43628	uniprotkb:Q06124	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680985|mint:MINT-8035677	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8035681(identity)|uniprotkb:P43628(original identifier)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-8035678(identity)|uniprotkb:Q06124(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2020/01/07	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:03323DBD30BFF5E5|rigid:zBRPhGBmKxMlQ3DqFcrJpcaajrE	false	binding-associated region:326-339(MINT-8035684)|phosphorylated residue:333-333(MINT-8035686)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43628	uniprotkb:P29350	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-78260|intact:EBI-28977917|ensembl:ENSP00000326010|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680949|mint:MINT-8035647	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8035651(identity)|uniprotkb:P43628(original identifier)	ensembl:ENSG00000111679(gene)|ensembl:ENST00000318974(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|rcsb pdb:3PS5|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|ensembl:ENSP00000326010|ensembl:ENST00000399448|ensembl:ENSP00000382376|ensembl:ENST00000456013|ensembl:ENSP00000391592|refseq:XP_011519290.1|dip:DIP-31002N|mint:MINT-8035648(identity)|uniprotkb:P29350(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:EEA8C48E1E6616C9|rigid:/fjALg7ovK9PWw+K3ScOWsHLU8U	false	binding-associated region:326-339(MINT-8035654)|phosphorylated residue:333-333(MINT-8035656)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43403	uniprotkb:P20963	intact:EBI-1211276|uniprotkb:A6NFP4|uniprotkb:Q6PIA4|uniprotkb:Q8IXD6|uniprotkb:Q9UBS6|ensembl:ENSP00000264972	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	psi-mi:zap70_human(display_long)|uniprotkb:ZAP70(gene name)|psi-mi:ZAP70(display_short)|uniprotkb:SRK(gene name synonym)|uniprotkb:Syk-related tyrosine kinase(gene name synonym)|uniprotkb:70 kDa zeta-chain associated protein(gene name synonym)	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8681039|mint:MINT-8036040	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070.2|refseq:NP_997402.1|dip:DIP-38781N|ensembl:ENSG00000115085(gene)|ensembl:ENST00000264972(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042113"(B cell activation)|go:"GO:0043366"(beta selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070489"(T cell aggregation)|go:"GO:0072678"(T cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43403|rcsb pdb:1FBV|rcsb pdb:1M61|rcsb pdb:1U59|rcsb pdb:2CBL|rcsb pdb:2OQ1|rcsb pdb:2OZO|rcsb pdb:2Y1N|rcsb pdb:3ZNI|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4K2R|rcsb pdb:4XZ0|rcsb pdb:4XZ1|rcsb pdb:5O76|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-9013407|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042110"(T cell activation)|mint:MINT-8036041(identity)|uniprotkb:P43403(original identifier)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|mint:MINT-8036044(identity)|uniprotkb:P20963(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:21kVb/nxY2BBZPBNVwWba+qUOgc9606	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	intact-crc:3F642B3D657B34AB|rigid:Pru20NE1fLdUUpLl9QVBqW5hXEc	false	-	phosphorylated residue:72-72(MINT-8036049)|binding-associated region:65-78(MINT-8036047)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43628	uniprotkb:Q06124	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680895|mint:MINT-8027417	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8027421(identity)|uniprotkb:P43628(original identifier)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-8027418(identity)|uniprotkb:Q06124(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2020/01/07	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:66846ABE9B428401|rigid:zBRPhGBmKxMlQ3DqFcrJpcaajrE	false	phosphorylated residue:303-303(MINT-8027426)|binding-associated region:296-309(MINT-8027424)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43628	uniprotkb:P29350	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-78260|intact:EBI-28977917|ensembl:ENSP00000326010|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680859|mint:MINT-8027387	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8027391(identity)|uniprotkb:P43628(original identifier)	ensembl:ENSG00000111679(gene)|ensembl:ENST00000318974(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|rcsb pdb:3PS5|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|ensembl:ENSP00000326010|ensembl:ENST00000399448|ensembl:ENSP00000382376|ensembl:ENST00000456013|ensembl:ENSP00000391592|refseq:XP_011519290.1|dip:DIP-31002N|mint:MINT-8027388(identity)|uniprotkb:P29350(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:78F3A8A6CE55A063|rigid:/fjALg7ovK9PWw+K3ScOWsHLU8U	false	phosphorylated residue:303-303(MINT-8027396)|binding-associated region:296-309(MINT-8027394)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P20963	uniprotkb:P43403	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	intact:EBI-1211276|uniprotkb:A6NFP4|uniprotkb:Q6PIA4|uniprotkb:Q8IXD6|uniprotkb:Q9UBS6|ensembl:ENSP00000264972	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:zap70_human(display_long)|uniprotkb:ZAP70(gene name)|psi-mi:ZAP70(display_short)|uniprotkb:SRK(gene name synonym)|uniprotkb:Syk-related tyrosine kinase(gene name synonym)|uniprotkb:70 kDa zeta-chain associated protein(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680913|mint:MINT-8032958	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|mint:MINT-8032962(identity)|uniprotkb:P20963(original identifier)	refseq:NP_001070.2|refseq:NP_997402.1|dip:DIP-38781N|ensembl:ENSG00000115085(gene)|ensembl:ENST00000264972(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042113"(B cell activation)|go:"GO:0043366"(beta selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070489"(T cell aggregation)|go:"GO:0072678"(T cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43403|rcsb pdb:1FBV|rcsb pdb:1M61|rcsb pdb:1U59|rcsb pdb:2CBL|rcsb pdb:2OQ1|rcsb pdb:2OZO|rcsb pdb:2Y1N|rcsb pdb:3ZNI|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4K2R|rcsb pdb:4XZ0|rcsb pdb:4XZ1|rcsb pdb:5O76|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-9013407|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042110"(T cell activation)|mint:MINT-8032959(identity)|uniprotkb:P43403(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	rogid:21kVb/nxY2BBZPBNVwWba+qUOgc9606	intact-crc:CFAC2EBCD5DAF238|rigid:Pru20NE1fLdUUpLl9QVBqW5hXEc	false	binding-associated region:76-89(MINT-8032965)|phosphorylated residue:83-83(MINT-8032967)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43628	uniprotkb:Q06124	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-297779|uniprotkb:Q96HD7|ensembl:ENSP00000340944|uniprotkb:A8K1D9|intact:EBI-14351608|intact:EBI-11988773|intact:EBI-13004965	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn11_human(display_long)|uniprotkb:PTPN11(gene name)|psi-mi:PTPN11(display_short)|uniprotkb:PTP2C(gene name synonym)|uniprotkb:SHPTP2(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 2C(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1D(gene name synonym)|uniprotkb:SH-PTP3(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8681003|mint:MINT-8035692	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8035696(identity)|uniprotkb:P43628(original identifier)	rcsb pdb:5I6V|rcsb pdb:5IBM|rcsb pdb:5IBS|rcsb pdb:5X7B|rcsb pdb:5X94|rcsb pdb:5XZR|rcsb pdb:6ATD|rcsb pdb:6BMR|rcsb pdb:6BMU|rcsb pdb:6BMV|rcsb pdb:6BMW|rcsb pdb:6BMX|rcsb pdb:6BMY|rcsb pdb:6BN5|rcsb pdb:6CMP|rcsb pdb:6CMQ|rcsb pdb:6CMR|rcsb pdb:6CMS|rcsb pdb:6CRF|rcsb pdb:6CRG|rcsb pdb:6MD7|rcsb pdb:6MD9|rcsb pdb:6MDA|rcsb pdb:6MDB|rcsb pdb:6MDC|rcsb pdb:6MDD|rcsb pdb:6R5G|rcsb pdb:6WU8|rcsb pdb:7EMN|rcsb pdb:7JVM|rcsb pdb:7JVN|reactome:R-HSA-1059683|reactome:R-HSA-109704|reactome:R-HSA-110056|reactome:R-HSA-112411|rcsb pdb:5EHR|reactome:R-HSA-114604|reactome:R-HSA-1170546|reactome:R-HSA-512988|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-1257604|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-1295596|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-1433557|reactome:R-HSA-180292|reactome:R-HSA-5654733|reactome:R-HSA-186763|reactome:R-HSA-6811558|reactome:R-HSA-210990|reactome:R-HSA-210993|reactome:R-HSA-877312|reactome:R-HSA-8853659|reactome:R-HSA-8854691|reactome:R-HSA-8865999|reactome:R-HSA-8934593|reactome:R-HSA-9008059|reactome:R-HSA-2219530|reactome:R-HSA-2586552|reactome:R-HSA-388841|reactome:R-HSA-389513|reactome:R-HSA-9028731|reactome:R-HSA-389948|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-391160|reactome:R-HSA-936964|reactome:R-HSA-418886|reactome:R-HSA-432142|reactome:R-HSA-9607240|reactome:R-HSA-9645135|reactome:R-HSA-9674555|reactome:R-HSA-9702518|reactome:R-HSA-9703648|ensembl:ENSG00000179295(gene)|ensembl:ENST00000351677(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|rcsb pdb:3ZM0|rcsb pdb:3ZM1|rcsb pdb:3ZM2|rcsb pdb:3ZM3|interpro:IPR029021|rcsb pdb:4DGP|rcsb pdb:4DGX|interpro:IPR036860|mint:Q06124|rcsb pdb:4GWF|rcsb pdb:4H1O|rcsb pdb:4H34|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4JMG|rcsb pdb:4NWF|rcsb pdb:4NWG|rcsb pdb:4OHD|rcsb pdb:4OHE|rcsb pdb:4OHH|rcsb pdb:4OHI|rcsb pdb:4OHL|rcsb pdb:2SHP|rcsb pdb:3B7O|rcsb pdb:3MOW|rcsb pdb:3O5X|rcsb pdb:3TKZ|rcsb pdb:3TL0|rcsb pdb:4PVG|rcsb pdb:4QSY|rcsb pdb:4RDD|rcsb pdb:5BK8|rcsb pdb:5DF6|rcsb pdb:5EHP|refseq:NP_002825.3|refseq:NP_542168.1|refseq:NP_001317366.1|dip:DIP-516N|mint:MINT-8035693(identity)|uniprotkb:Q06124(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2020/01/07	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:I1qRE/L3Wi7q+l/n0NnjKRQ5vqU9606	intact-crc:4466D023E8EBC2A7|rigid:zBRPhGBmKxMlQ3DqFcrJpcaajrE	false	phosphorylated residue:333-333(MINT-8035701)|binding-associated region:326-339(MINT-8035699)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43628	uniprotkb:P29350	intact:EBI-8632435|ensembl:ENSP00000342215|ensembl:ENSP00000478136|ensembl:ENSP00000478657|ensembl:ENSP00000478848|ensembl:ENSP00000479121|ensembl:ENSP00000480087|ensembl:ENSP00000480464|ensembl:ENSP00000481159|ensembl:ENSP00000481237|ensembl:ENSP00000481355|ensembl:ENSP00000481478|ensembl:ENSP00000482830|ensembl:ENSP00000483192|ensembl:ENSP00000483419|ensembl:ENSP00000483551|ensembl:ENSP00000483883|ensembl:ENSP00000483975|ensembl:ENSP00000484459|ensembl:ENSP00000491264|ensembl:ENSP00000491273|ensembl:ENSP00000491452|ensembl:ENSP00000491955|ensembl:ENSP00000492356|ensembl:ENSP00000492856|intact:MINT-1523646|uniprotkb:Q14945|uniprotkb:Q9UM51|uniprotkb:P78402|uniprotkb:Q14944|uniprotkb:Q9UQ70|uniprotkb:O43472	intact:EBI-78260|intact:EBI-28977917|ensembl:ENSP00000326010|uniprotkb:Q969V8|uniprotkb:A8K306|uniprotkb:G3V0F8|uniprotkb:Q9UK67	psi-mi:ki2l3_human(display_long)|uniprotkb:KIR2DL3(gene name)|psi-mi:KIR2DL3(display_short)|uniprotkb:KIRCL23(gene name synonym)|uniprotkb:NKAT2(gene name synonym)|uniprotkb:CD158B2(gene name synonym)|uniprotkb:MHC class I NK cell receptor(gene name synonym)|uniprotkb:Natural killer-associated transcript 2(gene name synonym)|uniprotkb:NKAT2a(gene name synonym)|uniprotkb:NKAT2b(gene name synonym)|uniprotkb:p58 natural killer cell receptor clone CL-6(gene name synonym)|uniprotkb:p58.2 MHC class-I-specific NK receptor(gene name synonym)|uniprotkb:Killer inhibitory receptor cl 2-3(gene name synonym)|uniprotkb:KIR-023GB(gene name synonym)|uniprotkb:CD158 antigen-like family member B2(gene name synonym)	psi-mi:ptn6_human(display_long)|uniprotkb:PTPN6(gene name)|psi-mi:PTPN6(display_short)|uniprotkb:HCP(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1C(gene name synonym)|uniprotkb:Hematopoietic cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:SH-PTP1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase SHP-1(gene name synonym)|uniprotkb:PTP1C(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8680967|mint:MINT-8035662	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000243772(gene)|ensembl:ENSG00000273887(gene)|ensembl:ENSG00000274108(gene)|ensembl:ENSG00000274402(gene)|ensembl:ENSG00000274410(gene)|ensembl:ENSG00000274830(gene)|ensembl:ENSG00000274952(gene)|ensembl:ENSG00000275008(gene)|ensembl:ENSG00000275623(gene)|ensembl:ENSG00000275658(gene)|ensembl:ENSG00000276218(gene)|ensembl:ENSG00000276459(gene)|ensembl:ENSG00000276590(gene)|ensembl:ENSG00000277317(gene)|ensembl:ENSG00000277484(gene)|ensembl:ENSG00000277554(gene)|ensembl:ENSG00000277924(gene)|ensembl:ENSG00000278327(gene)|ensembl:ENSG00000283702(gene)|ensembl:ENSG00000283708(gene)|ensembl:ENSG00000283790(gene)|ensembl:ENSG00000284333(gene)|ensembl:ENSG00000284504(gene)|ensembl:ENSG00000284510(gene)|ensembl:ENST00000342376(transcript)|ensembl:ENST00000610407(transcript)|ensembl:ENST00000611207(transcript)|ensembl:ENST00000611369(transcript)|ensembl:ENST00000611821(transcript)|ensembl:ENST00000611990(transcript)|ensembl:ENST00000614792(transcript)|ensembl:ENST00000615091(transcript)|ensembl:ENST00000615739(transcript)|ensembl:ENST00000617150(transcript)|ensembl:ENST00000617242(transcript)|ensembl:ENST00000617404(transcript)|ensembl:ENST00000617593(transcript)|ensembl:ENST00000617790(transcript)|ensembl:ENST00000619702(transcript)|ensembl:ENST00000619995(transcript)|ensembl:ENST00000620549(transcript)|ensembl:ENST00000622644(transcript)|ensembl:ENST00000638813(transcript)|ensembl:ENST00000638851(transcript)|ensembl:ENST00000639089(transcript)|ensembl:ENST00000639101(transcript)|ensembl:ENST00000639176(transcript)|ensembl:ENST00000640485(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1B6U|rcsb pdb:6PAG|reactome:R-HSA-198933|refseq:NP_056952.2|mint:MINT-8035666(identity)|uniprotkb:P43628(original identifier)	ensembl:ENSG00000111679(gene)|ensembl:ENST00000318974(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005001"(transmembrane receptor protein tyrosine phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0002924"(negative regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030220"(platelet formation)|go:"GO:0031295"(T cell costimulation)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045577"(regulation of B cell differentiation)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1905867"(epididymis development)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P29350|rcsb pdb:1FPR|rcsb pdb:1GWZ|rcsb pdb:1X6C|rcsb pdb:2B3O|rcsb pdb:2RMX|rcsb pdb:2YU7|rcsb pdb:4GRY|rcsb pdb:4GRZ|rcsb pdb:4GS0|rcsb pdb:4HJP|rcsb pdb:4HJQ|rcsb pdb:6SM5|reactome:R-HSA-114604|reactome:R-HSA-1433559|reactome:R-HSA-210990|reactome:R-HSA-388841|reactome:R-HSA-389948|reactome:R-HSA-391160|reactome:R-HSA-432142|reactome:R-HSA-512988|reactome:R-HSA-5690714|reactome:R-HSA-6798695|reactome:R-HSA-877300|reactome:R-HSA-877312|rcsb pdb:3PS5|reactome:R-HSA-9008059|reactome:R-HSA-909733|reactome:R-HSA-912526|reactome:R-HSA-912694|reactome:R-HSA-982772|reactome:R-HSA-983695|refseq:NP_002822.2|refseq:NP_536858.1|refseq:NP_536859.1|ensembl:ENSP00000326010|ensembl:ENST00000399448|ensembl:ENSP00000382376|ensembl:ENST00000456013|ensembl:ENSP00000391592|refseq:XP_011519290.1|dip:DIP-31002N|mint:MINT-8035663(identity)|uniprotkb:P29350(original identifier)	-	comment:mint|function:"Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis"	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:cb3YfQFCC2N0Y8ePoGNwZ9HQyFY9606	rogid:1o9Eaibzjx0irvkKKbwqq29wGts9606	intact-crc:A9FC2910C632218B|rigid:/fjALg7ovK9PWw+K3ScOWsHLU8U	false	phosphorylated residue:333-333(MINT-8035671)|binding-associated region:326-339(MINT-8035669)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43403	uniprotkb:P20963	intact:EBI-1211276|uniprotkb:A6NFP4|uniprotkb:Q6PIA4|uniprotkb:Q8IXD6|uniprotkb:Q9UBS6|ensembl:ENSP00000264972	intact:EBI-1165705|uniprotkb:Q5VX13|uniprotkb:Q8TAX4|uniprotkb:B1AK49|ensembl:ENSP00000354782	psi-mi:zap70_human(display_long)|uniprotkb:ZAP70(gene name)|psi-mi:ZAP70(display_short)|uniprotkb:SRK(gene name synonym)|uniprotkb:Syk-related tyrosine kinase(gene name synonym)|uniprotkb:70 kDa zeta-chain associated protein(gene name synonym)	psi-mi:cd3z_human(display_long)|uniprotkb:T-cell receptor T3 zeta chain(gene name synonym)|uniprotkb:CD247(gene name)|psi-mi:CD247(display_short)|uniprotkb:CD3Z(gene name synonym)|uniprotkb:T3Z(gene name synonym)|uniprotkb:TCRZ(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Olcese et al. (1996)	mint:MINT-6730623|pubmed:8648092	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8681021|mint:MINT-8036025	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070.2|refseq:NP_997402.1|dip:DIP-38781N|ensembl:ENSG00000115085(gene)|ensembl:ENST00000264972(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0042113"(B cell activation)|go:"GO:0043366"(beta selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045087"(innate immune response)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070489"(T cell aggregation)|go:"GO:0072678"(T cell migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR012234(Tyrosine protein kinase, SYK/ZAP-70)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR023420|interpro:IPR035838|interpro:IPR036860|mint:P43403|rcsb pdb:1FBV|rcsb pdb:1M61|rcsb pdb:1U59|rcsb pdb:2CBL|rcsb pdb:2OQ1|rcsb pdb:2OZO|rcsb pdb:2Y1N|rcsb pdb:3ZNI|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4K2R|rcsb pdb:4XZ0|rcsb pdb:4XZ1|rcsb pdb:5O76|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-9013407|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042110"(T cell activation)|mint:MINT-8036026(identity)|uniprotkb:P43403(original identifier)	refseq:NP_000725.1|refseq:NP_932170.1|ensembl:ENSG00000198821(gene)|ensembl:ENST00000362089(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042105"(alpha-beta T cell receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR003110(Phosphorylated immunoreceptor signaling ITAM)|interpro:IPR021663|mint:P20963|interpro:IPR024128|rcsb pdb:1TCE|rcsb pdb:1YGR|rcsb pdb:2HAC|rcsb pdb:2OQ1|rcsb pdb:3IK5|rcsb pdb:3IOZ|rcsb pdb:4XZ1|rcsb pdb:6JXR|reactome:R-HSA-164944|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-389948|reactome:R-HSA-9664323|reactome:R-HSA-9664422|dip:DIP-35404N|mint:MINT-8036029(identity)|uniprotkb:P20963(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:21kVb/nxY2BBZPBNVwWba+qUOgc9606	rogid:HUeUJ0AJmv3R4lCaiYPyLpzsP4U9606	intact-crc:7830C6A3BD2F03E9|rigid:Pru20NE1fLdUUpLl9QVBqW5hXEc	false	-	phosphorylated residue:72-72(MINT-8036034)|binding-associated region:65-78(MINT-8036032)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)