#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P07949	uniprotkb:P19174	intact:EBI-2480756|intact:EBI-28967738|ensembl:ENSP00000347942|uniprotkb:A8K6Z2|uniprotkb:Q9BTB0|uniprotkb:Q15250|uniprotkb:Q9H4A2	intact:EBI-79387|uniprotkb:Q2V575|uniprotkb:B9EGH4|uniprotkb:B7ZLY7|uniprotkb:E1P5W4|intact:EBI-3959906|ensembl:ENSP00000362368	psi-mi:ret_human(display_long)|uniprotkb:RET(gene name)|psi-mi:RET(display_short)|uniprotkb:CDHF12(gene name synonym)|uniprotkb:Cadherin family member 12(gene name synonym)|uniprotkb:Proto-oncogene c-Ret(gene name synonym)|uniprotkb:CDHR16(gene name synonym)|uniprotkb:PTC(gene name synonym)|uniprotkb:RET51(gene name synonym)	psi-mi:plcg1_human(display_long)|uniprotkb:PLC-148(gene name synonym)|uniprotkb:PLC1(gene name synonym)|uniprotkb:Phospholipase C-II(gene name synonym)|uniprotkb:PLCG1(gene name)|psi-mi:PLCG1(display_short)|uniprotkb:Phosphoinositide phospholipase C-gamma-1(gene name synonym)|uniprotkb:Phospholipase C-gamma-1(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Borrello et al. (1996)	mint:MINT-6730605|pubmed:8628282	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8678694|mint:MINT-8034153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165731(gene)|ensembl:ENST00000355710(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007497"(posterior midgut development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0033141"(positive regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002126(Cadherin)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015919(Cadherin-like)|interpro:IPR016249(Tyrosine-protein kinase, Ret receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR040667|interpro:IPR041163|interpro:IPR041317|go:"GO:0098797"(plasma membrane protein complex)|mint:P07949|rcsb pdb:1XPD|rcsb pdb:2IVS|rcsb pdb:2IVT|rcsb pdb:2IVU|rcsb pdb:2IVV|rcsb pdb:2X2K|rcsb pdb:2X2L|rcsb pdb:2X2M|rcsb pdb:2X2U|rcsb pdb:4CKI|go:"GO:0035799"(ureter maturation)|go:"GO:0035860"(glial cell-derived neurotrophic factor receptor signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042493"|go:"GO:0042551"(neuron maturation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045121"(membrane raft)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048265"(response to pain)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060384"(innervation)|go:"GO:0061146"(Peyer's patch morphogenesis)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0072300"(positive regulation of metanephric glomerulus development)|go:"GO:0097021"(lymphocyte migration into lymphoid organs)|go:"GO:0033674"(positive regulation of kinase activity)|rcsb pdb:4UX8|rcsb pdb:5AMN|rcsb pdb:5FM2|rcsb pdb:5FM3|rcsb pdb:6FEK|rcsb pdb:6GL7|rcsb pdb:6I82|rcsb pdb:6I83|rcsb pdb:6NE7|rcsb pdb:6NEC|rcsb pdb:6NJA|rcsb pdb:6Q2J|rcsb pdb:6Q2N|rcsb pdb:6Q2O|rcsb pdb:6Q2R|rcsb pdb:4CKJ|rcsb pdb:6Q2S|rcsb pdb:6VHG|rcsb pdb:7JU5|rcsb pdb:7JU6|reactome:R-HSA-5673001|reactome:R-HSA-8853659|ensembl:ENST00000340058|ensembl:ENSP00000344798|ensembl:ENSP00000347942|refseq:NP_065681.1|refseq:NP_066124.1|dip:DIP-41449N|mint:MINT-8034157(identity)|uniprotkb:P07949(original identifier)	refseq:NP_002651.2|refseq:NP_877963.1|dip:DIP-100N|ensembl:ENSG00000124181(gene)|ensembl:ENST00000373271(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001726"(ruffle)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042995"(cell projection)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0050429"(calcium-dependent phospholipase C activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR000980(SH2 motif)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001452(Src homology-3)|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016279(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma)|interpro:IPR017946|interpro:IPR018247|interpro:IPR028380|interpro:IPR035023|interpro:IPR035024|interpro:IPR035724|interpro:IPR035892|interpro:IPR036028|interpro:IPR036860|mint:P19174|rcsb pdb:1HSQ|rcsb pdb:2HSP|rcsb pdb:4EY0|rcsb pdb:4FBN|rcsb pdb:7NXE|reactome:R-HSA-1169408|reactome:R-HSA-1236382|reactome:R-HSA-1251932|reactome:R-HSA-1489509|reactome:R-HSA-167021|reactome:R-HSA-1855204|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029485|reactome:R-HSA-210990|reactome:R-HSA-212718|reactome:R-HSA-2424491|reactome:R-HSA-2871796|reactome:R-HSA-2871809|reactome:R-HSA-418890|reactome:R-HSA-5218921|reactome:R-HSA-5637810|reactome:R-HSA-5654219|reactome:R-HSA-5654221|reactome:R-HSA-5654227|reactome:R-HSA-5654228|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9026527|reactome:R-HSA-9027277|reactome:R-HSA-9034793|reactome:R-HSA-9664323|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|mint:MINT-8034154(identity)|uniprotkb:P19174(original identifier)	-	-	-	comment:homomint|comment:mint|partial coverage:partial coverage	taxid:-3(unknown)|taxid:-3(Unknown)	-	2010/09/28	2014/10/16	rogid:vNKdBK5ZYchweyidTdbDFkd02VM9606	rogid:pJsNLrqg3cUj0SdjoyLf+/91yBo9606	intact-crc:EB2930D996F5ACD7|rigid:Fwf0tCY0f0e6H66k3w4Sram2ztQ	false	binding-associated region:1008-1021(MINT-8034160)|phosphorylated residue:1015-1015(MINT-8034162)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)