#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O57861 uniprotkb:O57861 intact:EBI-8553242|intact:MINT-8081973|ensemblbacteria:BAA29190 intact:EBI-8553242|intact:MINT-8081973|ensemblbacteria:BAA29190 psi-mi:dp2l_pyrho(display_long)|uniprotkb:Exodeoxyribonuclease large subunit(gene name synonym)|uniprotkb:PH0121(locus name)|uniprotkb:polC(gene name)|psi-mi:polC(display_short) psi-mi:dp2l_pyrho(display_long)|uniprotkb:Exodeoxyribonuclease large subunit(gene name synonym)|uniprotkb:PH0121(locus name)|uniprotkb:polC(gene name)|psi-mi:polC(display_short) psi-mi:"MI:0071"(molecular sieving) Matsui et al. (2011) pubmed:21192935|mint:MINT-8081949|mint:d-10-01313|doi:10.1016/j.febslet.2010.12.040 taxid:70601(pyrho)|taxid:70601(Pyrococcus horikoshii) taxid:70601(pyrho)|taxid:70601(Pyrococcus horikoshii) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553263|mint:MINT-8081991 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_048053037.1|interpro:IPR030934|interpro:IPR006141(Intein splicing site)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR016033(DNA polymerase II large subunit DP2, N-terminal)|rcsb pdb:3O59|interpro:IPR004475(DNA polymerase II large subunit DP2)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003615(HNH nuclease)|interpro:IPR036844|ensemblbacteria:BAA29190(gene)|ensemblbacteria:BAA29190(transcript)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008852"(exodeoxyribonuclease I activity)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0042802"(identical protein binding)|rcsb pdb:7OEC|mint:MINT-8082047(identity) refseq:WP_048053037.1|interpro:IPR030934|interpro:IPR006141(Intein splicing site)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR016033(DNA polymerase II large subunit DP2, N-terminal)|rcsb pdb:3O59|interpro:IPR004475(DNA polymerase II large subunit DP2)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003615(HNH nuclease)|interpro:IPR036844|ensemblbacteria:BAA29190(gene)|ensemblbacteria:BAA29190(transcript)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008852"(exodeoxyribonuclease I activity)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0042802"(identical protein binding)|rcsb pdb:7OEC|mint:MINT-8081993(identity) - comment:mint|comment:"Stoichiometry: 2.2" comment:mint|comment:"Stoichiometry: 2.2" figure legend:f4b f4c|comment:mint taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/12/23 2022/01/21 rogid:Cyjkjyzbt98nWVSssj3q9XBGKAA70601 rogid:Cyjkjyzbt98nWVSssj3q9XBGKAA70601 intact-crc:97F9CD842DBFBCAC|rigid:8Gn+RhUp5ITc35gm+GjFrmt27dk false binding-associated region:792-1163(MINT-8082051)|his tag:?-?(MINT-8082048) binding-associated region:1-100(MINT-8082044)|his tag:?-?(MINT-8082041) 2 2 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O57861 uniprotkb:O57861 intact:EBI-8553242|intact:MINT-8081973|ensemblbacteria:BAA29190 intact:EBI-8553242|intact:MINT-8081973|ensemblbacteria:BAA29190 psi-mi:dp2l_pyrho(display_long)|uniprotkb:Exodeoxyribonuclease large subunit(gene name synonym)|uniprotkb:PH0121(locus name)|uniprotkb:polC(gene name)|psi-mi:polC(display_short) psi-mi:dp2l_pyrho(display_long)|uniprotkb:Exodeoxyribonuclease large subunit(gene name synonym)|uniprotkb:PH0121(locus name)|uniprotkb:polC(gene name)|psi-mi:polC(display_short) psi-mi:"MI:0016"(circular dichroism) Matsui et al. (2011) pubmed:21192935|mint:MINT-8081949|mint:d-10-01313|doi:10.1016/j.febslet.2010.12.040 taxid:70601(pyrho)|taxid:70601(Pyrococcus horikoshii) taxid:70601(pyrho)|taxid:70601(Pyrococcus horikoshii) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553296|mint:MINT-8082055 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_048053037.1|interpro:IPR030934|interpro:IPR006141(Intein splicing site)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR016033(DNA polymerase II large subunit DP2, N-terminal)|rcsb pdb:3O59|interpro:IPR004475(DNA polymerase II large subunit DP2)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003615(HNH nuclease)|interpro:IPR036844|ensemblbacteria:BAA29190(gene)|ensemblbacteria:BAA29190(transcript)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008852"(exodeoxyribonuclease I activity)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0042802"(identical protein binding)|rcsb pdb:7OEC|mint:MINT-8082063(identity) refseq:WP_048053037.1|interpro:IPR030934|interpro:IPR006141(Intein splicing site)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR016033(DNA polymerase II large subunit DP2, N-terminal)|rcsb pdb:3O59|interpro:IPR004475(DNA polymerase II large subunit DP2)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003615(HNH nuclease)|interpro:IPR036844|ensemblbacteria:BAA29190(gene)|ensemblbacteria:BAA29190(transcript)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008852"(exodeoxyribonuclease I activity)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0042802"(identical protein binding)|rcsb pdb:7OEC|mint:MINT-8082057(identity) - comment:mint|comment:"Stoichiometry: 2.2" comment:mint|comment:"Stoichiometry: 2.2" comment:mint|figure legend:sf2a sf2b taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/12/23 2022/01/21 rogid:Cyjkjyzbt98nWVSssj3q9XBGKAA70601 rogid:Cyjkjyzbt98nWVSssj3q9XBGKAA70601 intact-crc:9491DDC9019DBA96|rigid:8Gn+RhUp5ITc35gm+GjFrmt27dk false binding-associated region:792-1163(MINT-8082064) binding-associated region:1-100(MINT-8082058) 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O57861 uniprotkb:O57861 intact:EBI-8553242|intact:MINT-8081973|ensemblbacteria:BAA29190 intact:EBI-8553242|intact:MINT-8081973|ensemblbacteria:BAA29190 psi-mi:dp2l_pyrho(display_long)|uniprotkb:Exodeoxyribonuclease large subunit(gene name synonym)|uniprotkb:PH0121(locus name)|uniprotkb:polC(gene name)|psi-mi:polC(display_short) psi-mi:dp2l_pyrho(display_long)|uniprotkb:Exodeoxyribonuclease large subunit(gene name synonym)|uniprotkb:PH0121(locus name)|uniprotkb:polC(gene name)|psi-mi:polC(display_short) psi-mi:"MI:0051"(fluorescence technology) Matsui et al. (2011) pubmed:21192935|mint:MINT-8081949|mint:d-10-01313|doi:10.1016/j.febslet.2010.12.040 taxid:70601(pyrho)|taxid:70601(Pyrococcus horikoshii) taxid:70601(pyrho)|taxid:70601(Pyrococcus horikoshii) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8553323|mint:MINT-8082080 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_048053037.1|interpro:IPR030934|interpro:IPR006141(Intein splicing site)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR016033(DNA polymerase II large subunit DP2, N-terminal)|rcsb pdb:3O59|interpro:IPR004475(DNA polymerase II large subunit DP2)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003615(HNH nuclease)|interpro:IPR036844|ensemblbacteria:BAA29190(gene)|ensemblbacteria:BAA29190(transcript)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008852"(exodeoxyribonuclease I activity)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0042802"(identical protein binding)|rcsb pdb:7OEC|mint:MINT-8082082(identity) refseq:WP_048053037.1|interpro:IPR030934|interpro:IPR006141(Intein splicing site)|interpro:IPR003587(Hedgehog/intein hint, N-terminal)|interpro:IPR016033(DNA polymerase II large subunit DP2, N-terminal)|rcsb pdb:3O59|interpro:IPR004475(DNA polymerase II large subunit DP2)|interpro:IPR003586(Hedgehog/intein hint domain, C-terminal)|interpro:IPR003615(HNH nuclease)|interpro:IPR036844|ensemblbacteria:BAA29190(gene)|ensemblbacteria:BAA29190(transcript)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008852"(exodeoxyribonuclease I activity)|go:"GO:0016539"(intein-mediated protein splicing)|go:"GO:0042802"(identical protein binding)|rcsb pdb:7OEC|mint:MINT-8082086(identity) - comment:mint|comment:"Stoichiometry: 2.2" comment:mint|comment:"Stoichiometry: 2.2" comment:mint|figure legend:sf2c taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/12/23 2022/01/21 rogid:Cyjkjyzbt98nWVSssj3q9XBGKAA70601 rogid:Cyjkjyzbt98nWVSssj3q9XBGKAA70601 intact-crc:1C395E03B4C866C1|rigid:8Gn+RhUp5ITc35gm+GjFrmt27dk false binding-associated region:1-100(MINT-8082083) binding-associated region:792-1163(MINT-8082087) 2 2 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)