#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03372 uniprotkb:Q9NPJ6 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9Y2R5 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-1046443|ensembl:ENSP00000285298|uniprotkb:Q86X15 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt17_human(display_long)|uniprotkb:MRPS17(gene name)|psi-mi:MRPS17(display_short)|uniprotkb:RPMS17(gene name synonym)|uniprotkb:HSPC011(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS17m(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000239789(gene)|ensembl:ENST00000285298(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR039193|mint:Q9Y2R5|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|reactome:R-HSA-5389840|rcsb pdb:6ZSB|reactome:R-HSA-5419276|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|refseq:NP_057053.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:UDEpLcg5pGMMYvvc72HnPf9169U9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9NPD3 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-371823|ensembl:ENSP00000315476 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P60709 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q13093 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2828127|uniprotkb:A5HTT5|uniprotkb:Q15692|uniprotkb:Q8IVA2|uniprotkb:Q5VTT1|ensembl:ENSP00000274793|ensembl:ENSP00000445666 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:pafa_human(display_long)|uniprotkb:PLA2G7(gene name)|psi-mi:PLA2G7(display_short)|uniprotkb:PAFAH(gene name synonym)|uniprotkb:1-alkyl-2-acetylglycerophosphocholine esterase(gene name synonym)|uniprotkb:2-acetyl-1-alkylglycerophosphocholine esterase(gene name synonym)|uniprotkb:Group-VIIA phospholipase A2(gene name synonym)|uniprotkb:LDL-associated phospholipase A2(gene name synonym)|uniprotkb:PAF 2-acylhydrolase(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001161829.1|refseq:NP_005075.3|rcsb pdb:5YE7|rcsb pdb:5YE8|rcsb pdb:5YE9|rcsb pdb:5YEA|rcsb pdb:6M06|rcsb pdb:6M07|rcsb pdb:6M08|reactome:R-HSA-422085|rcsb pdb:5LZ9|ensembl:ENSG00000146070(gene)|ensembl:ENST00000274793(transcript)|ensembl:ENST00000537365(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034440"(lipid oxidation)|go:"GO:0034441"(plasma lipoprotein particle oxidation)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0062234"(platelet activating factor catabolic process)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR005065(Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II)|interpro:IPR016715(PAF acetylhydrolase)|interpro:IPR029058|rcsb pdb:3D59|rcsb pdb:3D5E|rcsb pdb:3F96|rcsb pdb:3F97|rcsb pdb:3F98|rcsb pdb:3F9C|rcsb pdb:5JAD|rcsb pdb:5JAH|rcsb pdb:5JAL|rcsb pdb:5JAN|rcsb pdb:5JAO|rcsb pdb:5JAP|rcsb pdb:5JAR|rcsb pdb:5JAS|rcsb pdb:5JAT|rcsb pdb:5JAU|rcsb pdb:5LP1|rcsb pdb:5I8P|rcsb pdb:5LYY|rcsb pdb:5LZ2|rcsb pdb:5LZ4|rcsb pdb:5I9I|rcsb pdb:5LZ5|rcsb pdb:5LZ7|rcsb pdb:5LZ8|refseq:XP_005249465.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:sIQBLnsepccGTe/560SUqLJ7EGw9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9H1R3 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-356910|uniprotkb:Q569L1|uniprotkb:Q96I84|ensembl:ENSP00000365152|ensembl:ENSP00000365162 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:mylk2_human(display_long)|uniprotkb:MYLK2(gene name)|psi-mi:MYLK2(display_short) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_149109.1|ensembl:ENSP00000365152|ensembl:ENSP00000365162|ensembl:ENSG00000101306(gene)|ensembl:ENST00000375985(transcript)|ensembl:ENST00000375994(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004687"(myosin light chain kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014816"(skeletal muscle satellite cell differentiation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030017"(sarcomere)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032971"(regulation of muscle filament sliding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042717|rcsb pdb:2LV6|rcsb pdb:3KF9 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:VfJn/QlOkBjTcPHsi+5EkEQY3/c9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P60866 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q15649 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2563564|uniprotkb:K7EQP1|uniprotkb:Q8WVJ3|uniprotkb:A8K493|ensembl:ENSP00000481504|ensembl:ENSP00000484687 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:znhi3_human(display_long)|uniprotkb:TRIP3(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 3(gene name synonym)|uniprotkb:Thyroid hormone receptor interactor 3(gene name synonym)|uniprotkb:HNF-4a coactivator(gene name synonym)|uniprotkb:ZNHIT3(gene name)|psi-mi:ZNHIT3(display_short) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_004764.1|ensembl:ENSG00000273611(gene)|ensembl:ENSG00000278574(gene)|ensembl:ENST00000617429(transcript)|ensembl:ENST00000620508(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0070761"(pre-snoRNP complex)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR040197|rcsb pdb:2YQQ|rcsb pdb:5L85|refseq:NP_001268361.1|refseq:NP_001268362.1|refseq:NP_001268363.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:SxaEXdRQAbzgxjubm6FKF2oJnOw9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q96HR3 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q5T2N8 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2880061|ensembl:ENSP00000368062|uniprotkb:Q8N1Z5 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:atd3c_human(display_long)|uniprotkb:ATAD3C(gene name)|psi-mi:ATAD3C(display_short) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000215915(gene)|ensembl:ENST00000378785(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T2N8|refseq:NP_001034300.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:JP1/f7Mg8jNYnXeYRsoIxhk6t+s9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q92552 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:O95793 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P51398 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-355912|uniprotkb:Q13044|uniprotkb:Q96Q20|uniprotkb:Q68CT7|uniprotkb:B4DP59|uniprotkb:E7EM60|uniprotkb:B4DY62|ensembl:ENSP00000341692|ensembl:ENSP00000357320 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt29_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)|uniprotkb:MRPS29(gene name synonym)|uniprotkb:Death-associated protein 3(gene name synonym)|uniprotkb:Ionizing radiation resistance conferring protein(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS29(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001186778.1|refseq:NP_004623.1|refseq:NP_387506.1|refseq:NP_001186779.1|refseq:NP_001186780.1|refseq:XP_005245537.1|refseq:XP_005245538.1|ensembl:ENSG00000132676(gene)|ensembl:ENST00000343043(transcript)|ensembl:ENST00000368336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368|interpro:IPR027417|mint:P51398|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016857780.1|refseq:XP_016857781.1|refseq:XP_016857782.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:xSIyqKH4F49Iu+AVuVThJWsi9EA9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P62269 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9Y399 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2880048|intact:EBI-28977422|ensembl:ENSP00000241600|ensembl:ENSP00000360850|uniprotkb:Q5T899|uniprotkb:Q9BSQ4 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt02_human(display_long)|uniprotkb:MRPS2(gene name)|psi-mi:MRPS2(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:CGI-91(orf name) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6RW5|ensembl:ENST00000241600(transcript)|ensembl:ENST00000371785(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0061668"(mitochondrial ribosome assembly)|ensembl:ENSG00000122140(gene)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|mint:Q9Y399|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|ensembl:ENSP00000241600|ensembl:ENSP00000360850|refseq:NP_057118.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:tlWj8Un0CmbnBQtZMYlJpvIpc/09606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9NVC6 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:O15440 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2880066|intact:EBI-11077394|uniprotkb:Q9UQC3|uniprotkb:O14517|uniprotkb:Q9UN85|uniprotkb:B9EIQ2|uniprotkb:Q9UNP5|ensembl:ENSP00000333926|uniprotkb:Q29ZA9|uniprotkb:Q29ZB1|uniprotkb:Q86W30|uniprotkb:Q86UX3 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:mrp5_human(display_long)|uniprotkb:ABCC5(gene name)|psi-mi:ABCC5(display_short)|uniprotkb:SMRP(gene name synonym)|uniprotkb:pABC11(gene name synonym)|uniprotkb:MRP5(gene name synonym)|uniprotkb:Multi-specific organic anion transporter C(gene name synonym)|uniprotkb:Multidrug resistance-associated protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:XP_011510616.1|refseq:XP_016860982.1|refseq:XP_016860983.1|refseq:NP_005679.2|ensembl:ENSG00000114770(gene)|ensembl:ENST00000334444(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0015216"(purine nucleotide transmembrane transporter activity)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015865"(purine nucleotide transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030213"(hyaluronan biosynthetic process)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0034775"(glutathione transmembrane transport)|go:"GO:0035351"(heme transmembrane transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070730"(cAMP transport)|go:"GO:0070731"(cGMP transport)|go:"GO:0098838"(folate transmembrane transport)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011527(ABC transporter, transmembrane region, type 1)|interpro:IPR017871|interpro:IPR027417|interpro:IPR030238|interpro:IPR036640|reactome:R-HSA-2142850|reactome:R-HSA-382556|go:"GO:0043225"(ATPase-coupled inorganic anion transmembrane transporter activity)|refseq:NP_001018881.1|refseq:NP_001306961.1|refseq:XP_005247115.1|refseq:XP_005247116.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:IG7hxo6LF3CWgrkzSKE+zn+6/PQ9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P62701 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P48552 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:O75376 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q96DU9 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2880076|ensembl:ENSP00000308012|uniprotkb:Q5JQF4|uniprotkb:Q9UFE5|uniprotkb:Q6P529|uniprotkb:A8K240 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:pabp5_human(display_long)|uniprotkb:PABPC5(gene name)|psi-mi:PABPC5(display_short)|uniprotkb:PABP5(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000174740(gene)|ensembl:ENST00000312600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0010494"(cytoplasmic stress granule)|refseq:NP_543022.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:IK1onIpa3e6rg71uj0b+i4i9o/k9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q96EY7 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q969Q0 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P11142 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P82650 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q7Z2W4 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P05388 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9BVJ6 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-473284|uniprotkb:B4DQ08|uniprotkb:E9PEL7|uniprotkb:Q5JYF1|uniprotkb:A8MVQ1|uniprotkb:A8K7A3|ensembl:ENSP00000377944 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:ut14a_human(display_long)|uniprotkb:Serologically defined colon cancer antigen 16(gene name synonym)|uniprotkb:Antigen NY-CO-16(gene name synonym)|uniprotkb:UTP14A(gene name)|psi-mi:UTP14A(display_short)|uniprotkb:SDCCAG16(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000156697(gene)|ensembl:ENST00000394422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0032040"(small-subunit processome)|interpro:IPR006709(Small-subunit processome, Utp14)|mint:Q9BVJ6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001159693.1|refseq:NP_006640.2|dip:DIP-32505N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:vBBHvYYgh4LYP335ktHlQ77Dkfc9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P82914 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q15637 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q92665 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P05089 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q92731 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P62280 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P61626 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-355360|ensembl:ENSP00000261267|uniprotkb:P00695|uniprotkb:Q9UCF8|uniprotkb:Q13170 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:lysc_human(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:LZM(gene name synonym)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000090382(gene)|refseq:NP_000230.1|rcsb pdb:1GB7|rcsb pdb:1GB8|rcsb pdb:1GB9|rcsb pdb:1GBO|rcsb pdb:1GBW|rcsb pdb:1GBX|rcsb pdb:1GBY|rcsb pdb:1GBZ|rcsb pdb:1GDW|rcsb pdb:1GDX|rcsb pdb:1GE0|rcsb pdb:1GE1|rcsb pdb:1GE2|rcsb pdb:1GE3|rcsb pdb:1GE4|rcsb pdb:1GEV|rcsb pdb:1GEZ|rcsb pdb:1GF0|rcsb pdb:1GF3|rcsb pdb:1GF4|rcsb pdb:1GF5|rcsb pdb:1GF6|rcsb pdb:1GF7|rcsb pdb:1GF8|rcsb pdb:1GF9|rcsb pdb:1GFA|rcsb pdb:1GFE|rcsb pdb:1GFG|rcsb pdb:1GFH|rcsb pdb:1GFJ|rcsb pdb:1GFK|rcsb pdb:1GFR|rcsb pdb:1GFT|rcsb pdb:1GFU|rcsb pdb:1GFV|rcsb pdb:1HNL|rcsb pdb:1I1Z|rcsb pdb:1I20|rcsb pdb:1I22|rcsb pdb:1INU|rcsb pdb:1IOC|rcsb pdb:1IP1|rcsb pdb:1IP2|rcsb pdb:1IP3|rcsb pdb:1IP4|rcsb pdb:1IP5|rcsb pdb:1IP6|rcsb pdb:1IP7|rcsb pdb:1IWT|rcsb pdb:1IWU|rcsb pdb:1IWV|rcsb pdb:1IWW|rcsb pdb:1IWX|rcsb pdb:1IWY|rcsb pdb:1IWZ|rcsb pdb:1IX0|rcsb pdb:1IY3|rcsb pdb:1IY4|rcsb pdb:1JKA|rcsb pdb:1JKB|rcsb pdb:1JKC|rcsb pdb:1JKD|rcsb pdb:1JSF|rcsb pdb:1JWR|rcsb pdb:1LAA|rcsb pdb:1LHH|rcsb pdb:1LHI|rcsb pdb:1LHJ|rcsb pdb:1LHK|rcsb pdb:1LHL|rcsb pdb:1LHM|rcsb pdb:1LMT|rcsb pdb:1LOZ|rcsb pdb:1LYY|rcsb pdb:1LZ1|rcsb pdb:1LZ4|rcsb pdb:1LZ5|rcsb pdb:1LZ6|rcsb pdb:1LZR|rcsb pdb:1LZS|rcsb pdb:1OP9|rcsb pdb:1OUA|rcsb pdb:1OUB|rcsb pdb:1OUC|rcsb pdb:1OUD|rcsb pdb:1OUE|rcsb pdb:1OUF|rcsb pdb:1OUG|rcsb pdb:1OUH|rcsb pdb:1OUI|rcsb pdb:1OUJ|rcsb pdb:1QSW|rcsb pdb:1RE2|rcsb pdb:1REM|rcsb pdb:1REX|rcsb pdb:1REY|rcsb pdb:1REZ|rcsb pdb:1TAY|rcsb pdb:1TBY|rcsb pdb:1TCY|rcsb pdb:1TDY|rcsb pdb:1UBZ|rcsb pdb:5LVK|rcsb pdb:6LFH|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1W08|rcsb pdb:1WQM|rcsb pdb:1WQN|rcsb pdb:1WQO|rcsb pdb:1WQP|rcsb pdb:1WQQ|rcsb pdb:1WQR|rcsb pdb:1YAM|rcsb pdb:1YAN|rcsb pdb:1YAO|rcsb pdb:1YAP|rcsb pdb:1YAQ|rcsb pdb:207L|rcsb pdb:208L|rcsb pdb:2BQA|rcsb pdb:2BQB|rcsb pdb:2BQC|rcsb pdb:2BQD|rcsb pdb:2BQE|rcsb pdb:2BQF|rcsb pdb:2BQG|rcsb pdb:2BQH|rcsb pdb:2BQI|rcsb pdb:2BQJ|rcsb pdb:2BQK|rcsb pdb:2BQL|rcsb pdb:2BQM|rcsb pdb:2BQN|rcsb pdb:2BQO|rcsb pdb:2HEA|rcsb pdb:2HEB|rcsb pdb:2HEC|rcsb pdb:2HED|rcsb pdb:2HEE|rcsb pdb:2HEF|rcsb pdb:2LHM|rcsb pdb:2MEA|rcsb pdb:2MEB|rcsb pdb:2MEC|rcsb pdb:2MED|rcsb pdb:2MEE|rcsb pdb:2MEF|rcsb pdb:2MEG|rcsb pdb:2MEH|rcsb pdb:2MEI|rcsb pdb:2NWD|rcsb pdb:2ZIJ|rcsb pdb:2ZIK|rcsb pdb:2ZIL|rcsb pdb:2ZWB|rcsb pdb:3EBA|rcsb pdb:3FE0|rcsb pdb:3LHM|rcsb pdb:3LN2|rcsb pdb:4I0C|rcsb pdb:4ML7|rcsb pdb:4R0P|rcsb pdb:5LSH|rcsb pdb:1B5X|rcsb pdb:1B5Y|rcsb pdb:1B5Z|rcsb pdb:1B7L|rcsb pdb:1B7M|rcsb pdb:1B7N|rcsb pdb:1B7O|rcsb pdb:1B7P|rcsb pdb:1B7Q|rcsb pdb:1B7R|rcsb pdb:1B7S|rcsb pdb:1BB3|rcsb pdb:1BB4|rcsb pdb:1BB5|rcsb pdb:1C43|rcsb pdb:1C45|rcsb pdb:1C46|rcsb pdb:1C7P|rcsb pdb:1CJ6|rcsb pdb:1CJ7|rcsb pdb:1CJ8|ensembl:ENST00000261267(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008152"(metabolic process)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|mint:P61626|rcsb pdb:133L|rcsb pdb:134L|rcsb pdb:1B5U|rcsb pdb:1B5V|rcsb pdb:1B5W|rcsb pdb:1CJ9|rcsb pdb:1CKC|rcsb pdb:1CKD|rcsb pdb:1CKF|rcsb pdb:1CKG|rcsb pdb:1CKH|rcsb pdb:1D6P|rcsb pdb:1D6Q|rcsb pdb:1DI3|rcsb pdb:1DI4|rcsb pdb:1DI5|rcsb pdb:1EQ4|rcsb pdb:1EQ5|rcsb pdb:1EQE|rcsb pdb:1GAY|rcsb pdb:1GAZ|rcsb pdb:1GB0|rcsb pdb:1GB2|rcsb pdb:1GB3|rcsb pdb:1GB5|rcsb pdb:1GB6 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:jydNN9yuU9EYvnth+kv115svRxw9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9H293 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2880054|ensembl:ENSP00000328111|uniprotkb:Q2M3F0|uniprotkb:Q8IZV3|uniprotkb:Q8WXB0 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:il25_human(display_long)|uniprotkb:IL25(gene name)|psi-mi:IL25(display_short)|uniprotkb:IL17E(gene name synonym)|uniprotkb:Interleukin-17E(gene name synonym)|uniprotkb:UNQ3120/PRO10272(orf name) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000166090(gene)|ensembl:ENST00000329715(transcript)|go:"GO:0005125"(cytokine activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0009620"(response to fungus)|go:"GO:0009624"(response to nematode)|go:"GO:0030222"(eosinophil differentiation)|go:"GO:0030380"(interleukin-17E receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR010345(Interleukin-17)|interpro:IPR029034|reactome:R-HSA-448424|go:"GO:0002437"(inflammatory response to antigenic stimulus)|refseq:NP_073626.1|refseq:NP_758525.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:mqkGukin1IeQ9zaft1M1ONMNtpM9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q8NHW5 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-355416 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rla0l_human(display_long)|uniprotkb:RPLP0P6(gene name)|psi-mi:RPLP0P6(display_short)|uniprotkb:Large ribosomal subunit protein uL10-like(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB interpro:IPR001790(Ribosomal protein L10)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR040637|interpro:IPR030670|interpro:IPR043141|interpro:IPR043164 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:mwr/+G18VKkJ2yrEjIMbz9m058o9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P82932 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:P82673 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2513649|ensembl:ENSP00000081029|uniprotkb:Q6P4C6|uniprotkb:Q7L1M6|uniprotkb:Q9HC14|uniprotkb:Q96AI0|uniprotkb:Q32LZ1|uniprotkb:Q9H044|uniprotkb:Q9P1R5|uniprotkb:Q8NBP4 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:rt35_human(display_long)|uniprotkb:MRPS35(gene name)|psi-mi:MRPS35(display_short)|uniprotkb:MRPS28(gene name synonym)|uniprotkb:28S ribosomal protein S28, mitochondrial(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS35(gene name synonym)|uniprotkb:HDCMD11P(orf name)|uniprotkb:MDS023(orf name)|uniprotkb:PSEC0213(orf name) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB ensembl:ENSG00000061794(gene)|ensembl:ENST00000081029(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR019349|interpro:IPR039848|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001177793.1|refseq:NP_068593.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:L7fhBRRkth1ePVbRtuVTvC5zcR09606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:O15164 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:P03372 uniprotkb:Q9Y6Q9 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45 psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym) psi-mi:"MI:0096"(pull down) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880046|imex:IM-13781-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N psi-mi:"MI:0469"(intact) - - figure legend:Table S1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2014/10/16 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606 intact-crc:851E92FBDB68F908|rigid:GNPBTru7xDYtg3o/CvAX0AkT6UA false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P35251 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P35249 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P35250 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y446 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880227|ensembl:ENSP00000331678|uniprotkb:F8J390|uniprotkb:Q53EX8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pkp3_human(display_long)|uniprotkb:PKP3(gene name)|psi-mi:PKP3(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000184363(gene)|ensembl:ENST00000331563(transcript)|go:"GO:0002159"(desmosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006417"(regulation of translation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0001533"(cornified envelope)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028434|interpro:IPR028435|mint:Q9Y446|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|refseq:NP_001289958.1|refseq:NP_009114.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:zGNbdze5MA5Mnf8m9IWZsxAPjAQ9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BVP2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000394799|ensembl:ENSP00000378278|ensembl:ENSP00000395772|refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938(gene)|ensembl:ENST00000418458(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030496"(midbody)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|mint:Q9BVP2|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62805 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q13610 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q68CK6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880280|ensembl:ENSP00000327453|ensembl:ENSP00000390378|ensembl:ENSP00000454995|ensembl:ENSP00000456378|uniprotkb:Q86YT1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:acs2b_human(display_long)|uniprotkb:ACSM2B(gene name)|psi-mi:ACSM2B(display_short)|uniprotkb:ACSM2(gene name synonym)|uniprotkb:Acyl-CoA synthetase medium-chain family member 2B(gene name synonym)|uniprotkb:Butyrate--CoA ligase 2B(gene name synonym)|uniprotkb:Butyryl-coenzyme A synthetase 2B(gene name synonym)|uniprotkb:Middle-chain acyl-CoA synthetase 2B(gene name synonym)|uniprotkb:Xenobiotic/medium-chain fatty acid-CoA ligase HXM-A(gene name synonym)|uniprotkb:HYST1046(orf name)|uniprotkb:Benzoate--CoA ligase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000414188(transcript)|ensembl:ENST00000565232(transcript)|ensembl:ENST00000567001(transcript)|go:"GO:0004321"(fatty-acyl-CoA synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0015645"(fatty acid ligase activity)|go:"GO:0016405"(CoA-ligase activity)|go:"GO:0018858"(benzoate-CoA ligase activity)|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000066813(gene)|ensembl:ENST00000329697(transcript)|go:"GO:0047760"(butyrate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR042099|reactome:R-HSA-177128|reactome:R-HSA-177135|go:"GO:0102391"(decanoate-CoA ligase activity)|reactome:R-HSA-177162|refseq:NP_001098539.1|refseq:NP_872423.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:AqOW1hNfGe+Fdpll6LpG7+Jq2Aw9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P12273 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96PK6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q71UM5 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P08107 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P47914 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q02383 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2609565|uniprotkb:Q6X2M6|uniprotkb:Q53ZU2|uniprotkb:Q6X2M5|ensembl:ENSP00000361855 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:semg2_human(display_long)|uniprotkb:SEMG2(gene name)|psi-mi:SEMG2(display_short)|uniprotkb:Semenogelin II(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_002999.1|ensembl:ENSG00000124157(gene)|ensembl:ENST00000372769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050817"(coagulation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900005"(positive regulation of serine-type endopeptidase activity)|go:"GO:1901318"(negative regulation of flagellated sperm motility)|interpro:IPR008836(Semenogelin)|mint:Q02383 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Ftsnc12KC4KSzLwCnoLmImTNPaI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62269 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O76041 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880203|ensembl:ENSP00000366326|uniprotkb:B0YJ45|uniprotkb:Q2TBD0|uniprotkb:Q9UIC4|uniprotkb:B9EIM9|uniprotkb:E9PRX7|uniprotkb:Q5VZT2|uniprotkb:Q70I54 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nebl_human(display_long)|uniprotkb:NEBL(gene name)|psi-mi:NEBL(display_short)|uniprotkb:Actin-binding Z-disk protein(gene name synonym)|uniprotkb:LNEBL(gene name synonym)|uniprotkb:C10orf113(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000078114(gene)|ensembl:ENST00000377122(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0031005"(filamin binding)|go:"GO:0031674"(I band)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035631|interpro:IPR036028|mint:O76041|rcsb pdb:4F14|refseq:NP_006384.1|refseq:NP_001166955.1|refseq:NP_998734.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:6+3t3OOFerBzWUyX3qtfz4DhFdg9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BY44 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1776615|uniprotkb:Q5QTR2|uniprotkb:Q7Z4E9|uniprotkb:Q8NFM1|uniprotkb:Q96EW9|uniprotkb:Q96K81|uniprotkb:A8MPS6|uniprotkb:B4DF96|uniprotkb:B4DQ14|uniprotkb:D3DNI9|ensembl:ENSP00000417229 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:eif2a_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short)|uniprotkb:CDA02(orf name)|uniprotkb:MSTP004(orf name)|uniprotkb:MSTP089(orf name)|uniprotkb:65 kDa eukaryotic translation initiation factor 2A(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_114414.2|refseq:NP_001305972.1|refseq:NP_001305973.1|refseq:NP_001305974.1|refseq:NP_001305975.1|dip:DIP-40272N|ensembl:ENSG00000144895(gene)|ensembl:ENST00000460851(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9BY44 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:67hYEz0CrhoQ7SfXxZdOWqKzil89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O60812 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1046507|uniprotkb:B2RP44|ensembl:ENSP00000488130|ensembl:ENSP00000365370 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hnrc1_human(display_long)|uniprotkb:HNRPCL1(gene name synonym)|uniprotkb:HNRNPCL1(gene name)|psi-mi:HNRNPCL1(display_short)|uniprotkb:hnRNP core protein C-like 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000317869(transcript)|ensembl:ENST00000634171(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:O60812|ensembl:ENSG00000179172(gene)|ensembl:ENSG00000282175(gene)|refseq:NP_001013653.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:yZcgZPlu3iuq0FR7hEQ0cvSo8K49606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P50416 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2817330|uniprotkb:Q9BWK0|uniprotkb:Q8TCU0|ensembl:ENSP00000265641|ensembl:ENSP00000446108 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cpt1a_human(display_long)|uniprotkb:CPT1A(gene name)|psi-mi:CPT1A(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine O-palmitoyltransferase I, liver isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1A(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001027017.1|refseq:NP_001867.2|refseq:XP_016872709.1|ensembl:ENSG00000110090(gene)|ensembl:ENST00000265641(transcript)|ensembl:ENST00000539743(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0045471"(response to ethanol)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097421"(liver regeneration)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|mint:P50416|rcsb pdb:2LE3|reactome:R-HSA-1368082|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-5362517 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:fmB4d9VHyWPyV0uTf00NkOr/fM49606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O43823 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1237481|ensembl:ENSP00000269701 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:akap8_human(display_long)|uniprotkb:AKAP8(gene name)|psi-mi:AKAP8(display_short)|uniprotkb:AKAP95(gene name synonym)|uniprotkb:A-kinase anchor protein 95 kDa(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005849.1|dip:DIP-38194N|ensembl:ENSG00000105127(gene)|ensembl:ENST00000269701(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0033127"(regulation of histone phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044839"(cell cycle G2/M phase transition)|go:"GO:0045087"(innate immune response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|interpro:IPR007071("A-kinase anchoring protein 95 (AKAP95)")|interpro:IPR034736|mint:O43823|go:"GO:0051059"(NF-kappaB binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:VtRlGSvkRqrzAcnq2Fj6fToZifY9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P08708 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-358255|uniprotkb:B2R4U4|intact:EBI-8012092|intact:EBI-11603362|intact:MINT-8395037|uniprotkb:P0CW22|ensembl:ENSP00000483755|ensembl:ENSP00000498019 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs17_human(display_long)|uniprotkb:RPS17(gene name)|psi-mi:RPS17(display_short)|uniprotkb:Small ribosomal subunit protein eS17(gene name synonym)|uniprotkb:RPS17L(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001012.1|ensembl:ENSG00000182774(gene)|ensembl:ENSG00000278229(gene)|ensembl:ENST00000617731(transcript)|ensembl:ENST00000647841(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401|mint:P08708|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|go:"GO:0034101"(erythrocyte homeostasis)|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:st+xQCXdSObiy6cJD1cSx869V289606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BQ39 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q63ZY3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2556193|uniprotkb:Q9H8S4|uniprotkb:Q6GUF5|uniprotkb:Q9NUP0|uniprotkb:Q3KQZ3|uniprotkb:B0I1P4|uniprotkb:Q9P210|ensembl:ENSP00000465650 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:kank2_human(display_long)|uniprotkb:ANKRD25(gene name synonym)|uniprotkb:KIAA1518(gene name synonym)|uniprotkb:MXRA3(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 25(gene name synonym)|uniprotkb:SRC-1-interacting protein(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 3(gene name synonym)|uniprotkb:KANK2(gene name)|psi-mi:KANK2(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001129663.1|refseq:NP_056308.3|rcsb pdb:6TMD|ensembl:ENSG00000197256(gene)|ensembl:ENST00000586659(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0070563"(negative regulation of vitamin D receptor signaling pathway)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|mint:Q63ZY3|rcsb pdb:4HBD|rcsb pdb:5YBV|refseq:NP_001316380.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:5lZ6UWmx5+N6B1B/xTmVfvxA7Ag9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9P2M7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-79537|intact:EBI-28986579|ensembl:ENSP00000271636|uniprotkb:Q5T386|uniprotkb:Q9NR25|uniprotkb:A6H8L3|uniprotkb:A7MD22 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cing_human(display_long)|uniprotkb:CGN(gene name)|psi-mi:CGN(display_short)|uniprotkb:KIAA1319(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000143375(gene)|ensembl:ENST00000271636(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016459"(myosin complex)|go:"GO:0030054"(cell junction)|go:"GO:0045296"(cadherin binding)|interpro:IPR002928(Myosin tail)|mint:Q9P2M7|reactome:R-HSA-2173791|refseq:NP_065821.1|ensembl:ENSP00000271636|refseq:XP_005245422.1|dip:DIP-30947N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:RJ4soprXOGUAlMLVIikuoeMs3v09606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UHB6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351479|uniprotkb:Q2TAN7|uniprotkb:Q9BVF2|uniprotkb:Q9H8J1|uniprotkb:Q9HBN5|uniprotkb:Q9NX96|uniprotkb:Q9NXC3|uniprotkb:Q9NXU6|uniprotkb:Q9P0H8|uniprotkb:Q9UHB5|uniprotkb:B2RB09|ensembl:ENSP00000340184|uniprotkb:Q59FE8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lima1_human(display_long)|uniprotkb:PP624(orf name)|uniprotkb:LIMA1(gene name)|psi-mi:LIMA1(display_short)|uniprotkb:SREBP3(gene name synonym)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:EPLIN(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001107018.1|refseq:NP_001107019.1|refseq:NP_057441.1|refseq:XP_011536757.1|ensembl:ENSG00000050405(gene)|ensembl:ENST00000341247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031526"(brush border membrane)|go:"GO:0031529"(ruffle organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740|mint:Q9UHB6|rcsb pdb:2D8Y|refseq:NP_001230704.1|refseq:XP_016874919.1|dip:DIP-29633N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:sHqhe21LVzLJXgDMH6IcWukKNHE9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O95793 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-358174|uniprotkb:Q6GTM4|uniprotkb:Q9H5B5|intact:EBI-366174|uniprotkb:Q9H5B4|uniprotkb:Q9Y3Q2|uniprotkb:A8K9Z4|ensembl:ENSP00000360922|uniprotkb:E1P5Y1|uniprotkb:E1P608|uniprotkb:Q5JW29 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:stau1_human(display_long)|uniprotkb:STAU1(gene name)|psi-mi:STAU1(display_short)|uniprotkb:STAU(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001309856.1|refseq:NP_001309858.1|refseq:NP_001309859.1|refseq:NP_001032405.1|refseq:NP_004593.2|refseq:NP_059346.2|refseq:NP_059347.2|refseq:NP_059348.2|refseq:NP_001306063.1|refseq:NP_001306064.1|ensembl:ENSG00000124214(gene)|ensembl:ENST00000371856(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|refseq:XP_005260584.1|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR044475|mint:O95793|rcsb pdb:4DKK|rcsb pdb:6HTU|rcsb pdb:6SDW|rcsb pdb:6SDY psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uYjbWja/hG5M/3likHLe00Z2FgY9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q15029 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-357897|uniprotkb:Q9BUR0|uniprotkb:D3DX58|uniprotkb:B4DK30|ensembl:ENSP00000392094|ensembl:ENSP00000467805|uniprotkb:B4DMC0|uniprotkb:K7EJ81 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:u5s1_human(display_long)|uniprotkb:EFTUD2(gene name)|psi-mi:EFTUD2(display_short)|uniprotkb:KIAA0031(gene name synonym)|uniprotkb:SNRP116(gene name synonym)|uniprotkb:U5 snRNP-specific protein, 116 kDa(gene name synonym)|uniprotkb:Elongation factor Tu GTP-binding domain-containing protein 2(gene name synonym)|uniprotkb:SNU114 homolog(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001136077.1|refseq:NP_004238.3|refseq:NP_001245282.1|go:"GO:0042220"(response to cocaine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031950|interpro:IPR035647|interpro:IPR035655|interpro:IPR041095|interpro:IPR044121|mint:Q15029|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|go:"GO:0035690"|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000108883(gene)|ensembl:ENST00000426333(transcript)|ensembl:ENST00000591382(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030623"(U5 snRNA binding)|refseq:NP_001245283.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:/dBQ7TFnGr31AYrb5e215eQ4vfc9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BQG0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8IZL8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P11142 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00567 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8IY81 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-744088|uniprotkb:Q8N3A3|uniprotkb:Q8WXX1|uniprotkb:Q9BWM4|uniprotkb:Q9NXT6|uniprotkb:D3DU22|uniprotkb:B2RCA5|ensembl:ENSP00000396673 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:spb1_human(display_long)|uniprotkb:FTSJ3(gene name)|psi-mi:FTSJ3(display_short)|uniprotkb:SB92(orf name)|uniprotkb:Protein ftsJ homolog 3(gene name synonym)|uniprotkb:Putative rRNA methyltransferase 3(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060117.3|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR024576|interpro:IPR028589|interpro:IPR029063|mint:Q8IY81|reactome:R-HSA-6791226|ensembl:ENSG00000108592(gene)|ensembl:ENST00000427159(transcript)|go:"GO:0000453"(enzyme-directed rRNA 2'-O-methylation)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008650"("rRNA (uridine-2'-O-)-methyltransferase activity")|go:"GO:0016435"("rRNA (guanine) methyltransferase activity")|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0031167"(rRNA methylation)|go:"GO:0062105"(RNA 2'-O-methyltransferase activity)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR012920(Spb1, C-terminal) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:KIeyMWn9Zktm5lV7XI7v2bRA8og9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q03111 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1384215|uniprotkb:Q14768|ensembl:ENSP00000252674 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:enl_human(display_long)|uniprotkb:MLLT1(gene name)|psi-mi:MLLT1(display_short)|uniprotkb:ENL(gene name synonym)|uniprotkb:LTG19(gene name synonym)|uniprotkb:YEATS1(gene name synonym)|uniprotkb:YEATS domain-containing protein 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005925.2|ensembl:ENSG00000130382(gene)|ensembl:ENST00000252674(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008023"(transcription elongation factor complex)|interpro:IPR005033(YEATS)|interpro:IPR038704|interpro:IPR040930|rcsb pdb:5J9S|rcsb pdb:6HPW|rcsb pdb:6HPX|rcsb pdb:6HPY|rcsb pdb:6HPZ|rcsb pdb:6HQ0|rcsb pdb:6HT0|rcsb pdb:6HT1|rcsb pdb:6T1I|rcsb pdb:6T1J|rcsb pdb:6T1L|rcsb pdb:6T1M|rcsb pdb:6T1N|rcsb pdb:6T1O|rcsb pdb:7B0T|rcsb pdb:7B10|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:H+j5XCIlsBwjsia+gMfTFKev3mA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P82650 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q5JTH9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-310743|uniprotkb:Q5JTH8|uniprotkb:Q69YK4|uniprotkb:Q96E87|uniprotkb:Q9BUH3|uniprotkb:Q9Y4C7|intact:EBI-2558452|uniprotkb:B4DK00|uniprotkb:E9PCK7|intact:EBI-28986119|ensembl:ENSP00000360031|ensembl:ENSP00000446184 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rrp12_human(display_long)|uniprotkb:RRP12(gene name)|psi-mi:RRP12(display_short)|uniprotkb:KIAA0690(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001138586.1|refseq:NP_055994.2|refseq:NP_001271266.1|ensembl:ENST00000315563|ensembl:ENSP00000324315|ensembl:ENSP00000360031|ensembl:ENST00000414986|ensembl:ENSP00000414863|ensembl:ENSP00000446184|ensembl:ENSG00000052749(gene)|ensembl:ENST00000370992(transcript)|ensembl:ENST00000536831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold)|mint:Q5JTH9 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:O2Ih3mwXBDMynmqc4UzvizKVnNg9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P23396 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P82914 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P12883 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-519141|uniprotkb:Q14836|uniprotkb:Q14837|uniprotkb:Q14904|uniprotkb:Q16579|uniprotkb:Q2M1Y6|uniprotkb:Q92679|uniprotkb:Q9H1D5|ensembl:ENSP00000347507|uniprotkb:Q9UMM8|uniprotkb:A2TDB6|uniprotkb:B6D424|uniprotkb:Q9UDA2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myh7_human(display_long)|uniprotkb:Myosin heavy chain 7(gene name synonym)|uniprotkb:Myosin heavy chain, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Myosin heavy chain slow isoform(gene name synonym)|uniprotkb:MYH7(gene name)|psi-mi:MYH7(display_short)|uniprotkb:MYHCB(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000092054(gene)|ensembl:ENST00000355349(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007512"(adult heart development)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031449"(regulation of slow-twitch skeletal muscle fiber contraction)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:P12883|rcsb pdb:1IK2|rcsb pdb:2FXM|rcsb pdb:2FXO|rcsb pdb:3DTP|rcsb pdb:4DB1|rcsb pdb:4P7H|rcsb pdb:4PA0|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA4|rcsb pdb:4XA6|rcsb pdb:5CHX|rcsb pdb:5CJ0|rcsb pdb:5CJ1|rcsb pdb:5CJ4|rcsb pdb:5TBY|rcsb pdb:5WJ7|rcsb pdb:5WJB|rcsb pdb:5WLQ|rcsb pdb:5WLZ|rcsb pdb:5WME|rcsb pdb:6PF2|rcsb pdb:6PFP|refseq:NP_000248.2|refseq:XP_016876829.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Fz6cO12gihAyDMe06hLrQbrupbs9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92731 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P51116 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UHR4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2483278|ensembl:ENSP00000005260|uniprotkb:A4D268|uniprotkb:Q75L21|uniprotkb:Q75L22|uniprotkb:Q96CV4|uniprotkb:Q9H5F5|uniprotkb:Q9Y2M8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:bi2l1_human(display_long)|uniprotkb:BAIAP2L1(gene name)|psi-mi:BAIAP2L1(display_short)|uniprotkb:IRTKS(gene name synonym)|uniprotkb:Insulin receptor tyrosine kinase substrate(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000006453(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENST00000005260(transcript)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0009617"(response to bacterium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030060|interpro:IPR035592|interpro:IPR036028|rcsb pdb:2KXC|rcsb pdb:2LNH|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9035034|refseq:NP_061330.2|ensembl:ENSP00000005260|dip:DIP-53820N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ig7xSOv8h6Y4vYE0/n228+ZLWaM9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96AG4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q00577 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1045860|ensembl:ENSP00000332706|ensembl:ENSP00000499133 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pura_human(display_long)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)|uniprotkb:PURA(gene name)|psi-mi:PURA(display_short)|uniprotkb:PUR1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005850.1|ensembl:ENSG00000185129(gene)|ensembl:ENST00000331327(transcript)|ensembl:ENST00000651386(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030500|mint:Q00577 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:4NuTKCFE1X+wdaAs+0Brd8IsFS89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O94832 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-355634|uniprotkb:Q8NHP9|ensembl:ENSP00000324527|uniprotkb:A6H8V3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myo1d_human(display_long)|uniprotkb:MYO1D(gene name)|psi-mi:MYO1D(display_short)|uniprotkb:KIAA0727(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_056009.1|ensembl:ENSG00000176658(gene)|ensembl:ENST00000318217(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030424"(axon)|go:"GO:0030673"(axolemma)|go:"GO:0030900"(forebrain development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051641"(cellular localization)|go:"GO:0061502"(early endosome to recycling endosome transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097440"(apical dendrite)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001290208.1|interpro:IPR036961 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:EjrnXi04BVb6Z59cU3e5LW7EhRI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96EY7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96JP5 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1052613|uniprotkb:Q86V47|uniprotkb:Q96JP4|uniprotkb:Q96QA3|uniprotkb:A6NHC4|uniprotkb:A8MSG7|ensembl:ENSP00000339030 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:zfp91_human(display_long)|uniprotkb:ZFP91(gene name)|psi-mi:ZFP91(display_short)|uniprotkb:FKSG11(orf name)|uniprotkb:ZNF757(gene name synonym)|uniprotkb:Zinc finger protein 757(gene name synonym)|uniprotkb:Zinc finger protein 91 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZFP91(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001183980.1|refseq:NP_444251.1|ensembl:ENSG00000186660(gene)|ensembl:ENST00000316059(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JP5|rcsb pdb:2M9A|go:"GO:0004842"(ubiquitin-protein transferase activity) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:oQuzxnamj/z05P/rG8EXnXTjzz89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P83111 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2878119|ensembl:ENSP00000261893|uniprotkb:P83096 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lactb_human(display_long)|uniprotkb:LACTB(gene name)|psi-mi:LACTB(display_short)|uniprotkb:MRPL56(gene name synonym)|uniprotkb:UNQ843/PRO1781(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000103642(gene)|ensembl:ENST00000261893(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR001466(Beta-lactamase)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|refseq:NP_116246.2|refseq:NP_741982.1|refseq:NP_001275514.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:idqlmN9YYs76X8+d8+4LALz5WjM9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q7Z7A1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2563266|uniprotkb:A2A2Y1|uniprotkb:B2RP67|uniprotkb:Q3MN79|uniprotkb:Q5FWF8|uniprotkb:Q5JVD0|uniprotkb:Q9Y489|uniprotkb:Q8TEP3|uniprotkb:Q6MZR3|uniprotkb:Q6PKC1|intact:EBI-2796138|ensembl:ENSP00000362962 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cntrl_human(display_long)|uniprotkb:CEP1(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym)|uniprotkb:Centrosomal protein 1(gene name synonym)|uniprotkb:CNTRL(gene name)|psi-mi:CNTRL(display_short)|uniprotkb:CEP110(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_008949.4|ensembl:ENSG00000119397(gene)|ensembl:ENST00000373855(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016020"(membrane)|go:"GO:0035904"(aorta development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0090543"(Flemming body)|go:"GO:0090619"(meiotic spindle pole)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR028640|interpro:IPR032675|mint:Q7Z7A1|reactome:R-HSA-1839117|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5655302|reactome:R-HSA-8854518|refseq:XP_005251736.1|refseq:NP_001317691.1|dip:DIP-47280N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:wmPF3eCXN2WiNQIyd0CR3OGJROo9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62280 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y6Q9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62701 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8WUA4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1237062|uniprotkb:D6W557|ensembl:ENSP00000264720|ensembl:ENSP00000352536|uniprotkb:Q16632|uniprotkb:Q9BWI7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tf3c2_human(display_long)|uniprotkb:GTF3C2(gene name)|psi-mi:GTF3C2(display_short)|uniprotkb:KIAA0011(gene name synonym)|uniprotkb:Transcription factor IIIC subunit beta(gene name synonym)|uniprotkb:TF3C-beta(gene name synonym)|uniprotkb:Transcription factor IIIC 110 kDa subunit(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000115207(gene)|ensembl:ENST00000264720(transcript)|ensembl:ENST00000359541(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q8WUA4|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001030598.1|refseq:NP_001512.1|refseq:NP_001305838.1|dip:DIP-38213N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:D2SnUgtDMoh8axZsIMskwjmNW1c9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q15648 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H1R3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-356910|uniprotkb:Q569L1|uniprotkb:Q96I84|ensembl:ENSP00000365152|ensembl:ENSP00000365162 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:mylk2_human(display_long)|uniprotkb:MYLK2(gene name)|psi-mi:MYLK2(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_149109.1|ensembl:ENSP00000365152|ensembl:ENSP00000365162|ensembl:ENSG00000101306(gene)|ensembl:ENST00000375985(transcript)|ensembl:ENST00000375994(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004687"(myosin light chain kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014816"(skeletal muscle satellite cell differentiation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030017"(sarcomere)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032971"(regulation of muscle filament sliding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042717|rcsb pdb:2LV6|rcsb pdb:3KF9 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:VfJn/QlOkBjTcPHsi+5EkEQY3/c9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NPJ6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BV38 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UBC2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2556746|intact:EBI-28972990|ensembl:ENSP00000248070|uniprotkb:B4DKA3|uniprotkb:A2RRF3|uniprotkb:A5PL29 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ep15r_human(display_long)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_067058.1|ensembl:ENSP00000248070|ensembl:ENST00000455140|ensembl:ENSP00000393313|ensembl:ENST00000535753|ensembl:ENSP00000440103|ensembl:ENST00000597937|ensembl:ENSP00000472267|ensembl:ENST00000602022|ensembl:ENSP00000471981|ensembl:ENSG00000127527(gene)|ensembl:ENST00000248070(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0045296"(cadherin binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBC2|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0030132"(clathrin coat of coated pit)|refseq:NP_001245303.1|refseq:NP_001245304.1|refseq:NP_001245305.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:6Bsao5czetxRxIiy3O/rZox4U+Y9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q16637 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O75683 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2691252|uniprotkb:Q9UK24|uniprotkb:Q9BTZ5|uniprotkb:Q5T8U1|uniprotkb:Q9BRK9|ensembl:ENSP00000361092|ensembl:ENSP00000485909 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:surf6_human(display_long)|uniprotkb:SURF-6(gene name synonym)|uniprotkb:SURF6(gene name)|psi-mi:SURF6(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006744.2|refseq:NP_001265871.1|ensembl:ENSG00000148296(gene)|ensembl:ENSG00000281309(gene)|ensembl:ENST00000372022(transcript)|ensembl:ENST00000629980(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR007019(Surfeit locus 6)|interpro:IPR029190 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:1Yzf0+p31xuzJXSoaiz9THfjF0c9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q86XI8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2682158|ensembl:ENSP00000331363|uniprotkb:A0A087WWL5 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:zswm9_human(display_long)|uniprotkb:ZSWIM9(gene name)|psi-mi:ZSWIM9(display_short)|uniprotkb:C19orf68(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_955373.3|ensembl:ENSG00000185453(gene)|ensembl:ENST00000328759(transcript)|interpro:IPR040854|mint:Q86XI8|refseq:XP_006723268.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:4wOy3iLGFg7lgvbA8nWPUgIgS0w9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P18621 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q5VV67 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1045850|uniprotkb:Q5VV66|uniprotkb:Q6P3U5|uniprotkb:Q6P3W1|uniprotkb:Q76N31|uniprotkb:Q9BUJ3|uniprotkb:Q9BZE5|uniprotkb:Q9Y4E0|intact:EBI-28968769|ensembl:ENSP00000278070 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pprc1_human(display_long)|uniprotkb:PGC-1-related coactivator(gene name synonym)|uniprotkb:PPRC1(gene name)|psi-mi:PPRC1(display_short)|uniprotkb:KIAA0595(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSP00000278070|refseq:NP_055877.3|ensembl:ENSG00000148840(gene)|ensembl:ENST00000278070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034597|interpro:IPR034605|interpro:IPR034834|interpro:IPR035979|reactome:R-HSA-2151201|refseq:NP_001275656.1|refseq:NP_001275657.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:CzoJyQC7ZylKapYmIL3Ik5IxhBk9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6PKX4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880244|ensembl:ENSP00000372160|uniprotkb:Q4V9S3|uniprotkb:Q96LU2|uniprotkb:A6NNG3|uniprotkb:Q96HI2|uniprotkb:Q8WUZ8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:dok6_human(display_long)|uniprotkb:DOK6(gene name)|psi-mi:DOK6(display_short)|uniprotkb:DOK5L(gene name synonym)|uniprotkb:Downstream of tyrosine kinase 6(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000206052(gene)|ensembl:ENST00000382713(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037816|reactome:R-HSA-8853659|refseq:NP_689934.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:hMHjc6pZ74mtPXhTetfA9SvFdf49606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:A8CG34 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880179|ensembl:ENSP00000476236|uniprotkb:O75115|uniprotkb:Q9Y4S7|uniprotkb:Q9Y2N3|uniprotkb:A0A075B7F8|uniprotkb:A0A087WY75 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:p121c_human(display_long)|uniprotkb:POM121C(gene name)|psi-mi:POM121C(display_short)|uniprotkb:Nuclear pore membrane protein 121-2(gene name synonym)|uniprotkb:Pore membrane protein of 121 kDa C(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-5619107|ensembl:ENST00000607367(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR026054|interpro:IPR026090|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|ensembl:ENSG00000272391(gene)|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-165054|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|ensembl:ENSP00000476236|ensembl:ENST00000615331|ensembl:ENSP00000481575 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:eUcsTyNISsNFsSxbHCO5VuhzB4E9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62851 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q16643 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96HA1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-739990|ensembl:ENSP00000405562|uniprotkb:A8MXF9|uniprotkb:O75115|uniprotkb:Q9Y4S7|intact:EBI-948778|uniprotkb:A6NFS9|uniprotkb:A8CDT4|uniprotkb:A8K933|uniprotkb:Q96DI0|uniprotkb:Q9H9X1|uniprotkb:Q9Y2N3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:p121a_human(display_long)|uniprotkb:POM121(gene name)|psi-mi:POM121(display_short)|uniprotkb:KIAA0618(gene name synonym)|uniprotkb:NUP121(gene name synonym)|uniprotkb:POM121A(gene name synonym)|uniprotkb:Pore membrane protein of 121 kDa(gene name synonym)|uniprotkb:Nuclear envelope pore membrane protein POM 121A(gene name synonym)|uniprotkb:Nucleoporin Nup121(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000196313(gene)|ensembl:ENST00000434423(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR026054|interpro:IPR026090|rcsb pdb:5T6W|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|refseq:NP_001244119.1|ensembl:ENST00000358357|ensembl:ENSP00000351124|ensembl:ENST00000395270|ensembl:ENSP00000378687|ensembl:ENSP00000405562|ensembl:ENST00000446813|ensembl:ENSP00000393020|ensembl:ENST00000627934|ensembl:ENSP00000486504|reactome:R-HSA-165054|refseq:NP_742017.1|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005250783.1|refseq:XP_006716259.1|refseq:XP_016868342.1|refseq:XP_016868343.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:lQ9VaBl42KMRJaM4UdF4ng9ZX549606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62277 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6PJG2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2795569|uniprotkb:Q6PK13|uniprotkb:Q6PK59|uniprotkb:Q6ZS23|intact:EBI-28972055|ensembl:ENSP00000286523|ensembl:ENSP00000377634 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:mdeas_human(display_long)|uniprotkb:MIDEAS(gene name)|psi-mi:MIDEAS(display_short)|uniprotkb:C14orf117(gene name synonym)|uniprotkb:C14orf43(gene name synonym)|uniprotkb:ELM2 and SANT domain-containing protein 1(gene name synonym)|uniprotkb:ELMSAN1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSP00000286523|ensembl:ENSP00000377634|refseq:NP_001036783.1|refseq:NP_919254.2|ensembl:ENSG00000156030(gene)|ensembl:ENST00000286523(transcript)|ensembl:ENST00000394071(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|rcsb pdb:6Z2J|rcsb pdb:6Z2K psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:wZyVPfF6zuF0ObDUtE0t0e0IK1M9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O15020 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-308449|uniprotkb:O14872|uniprotkb:O14873|ensembl:ENSP00000311489|ensembl:ENSP00000432568|ensembl:ENSP00000480692|ensembl:ENSP00000508362 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:sptn2_human(display_long)|uniprotkb:SPTBN2(gene name)|psi-mi:SPTBN2(display_short)|uniprotkb:KIAA0302(gene name synonym)|uniprotkb:Beta-III spectrin(gene name synonym)|uniprotkb:SCA5(gene name synonym)|uniprotkb:Spinocerebellar ataxia 5 protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000173898(gene)|ensembl:ENST00000309996(transcript)|ensembl:ENST00000533211(transcript)|ensembl:ENST00000611817(transcript)|ensembl:ENST00000647510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007416"(synapse assembly)|go:"GO:0008091"(spectrin)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:O15020|rcsb pdb:1WJM|rcsb pdb:1WYQ|rcsb pdb:6ANU|reactome:R-HSA-2132295|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|refseq:XP_005274249.1|refseq:XP_005274250.1|refseq:XP_006718734.1|refseq:XP_016873663.1|refseq:XP_016873664.1|refseq:XP_016873665.1|refseq:XP_016873666.1|refseq:XP_016873667.1|dip:DIP-47270N|refseq:NP_008877.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Wfzccja70pnee8sDDc0TCmO6g0I9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96J92 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-766352|uniprotkb:Q8N8X3|uniprotkb:Q8N8Z2|uniprotkb:Q96DT8|uniprotkb:Q9BYS5|uniprotkb:B0LPI0|intact:EBI-28967389|ensembl:ENSP00000246914 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:wnk4_human(display_long)|uniprotkb:Protein kinase with no lysine 4(gene name synonym)|uniprotkb:Protein kinase lysine-deficient 4(gene name synonym)|uniprotkb:WNK4(gene name)|psi-mi:WNK4(display_short)|uniprotkb:PRKWNK4(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_115763.2|ensembl:ENSP00000246914|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050794"(regulation of cellular process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0070294"(renal sodium ion absorption)|go:"GO:0072156"(distal tubule morphogenesis)|go:"GO:0090188"(negative regulation of pancreatic juice secretion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0019869"(chloride channel inhibitor activity)|ensembl:ENSG00000126562(gene)|ensembl:ENST00000246914(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006811"(ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0008104"(protein localization)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0016020"(membrane)|interpro:IPR024678|mint:Q96J92|rcsb pdb:2V3S|rcsb pdb:4CH9|rcsb pdb:4CHB|reactome:R-HSA-2672351 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:RiSrW6NfbbSbmUZixfxAvv+QnEU9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62424 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q7Z2W4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O15226 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-766011|uniprotkb:Q4VC41|uniprotkb:Q9UJ91|uniprotkb:G3V1N1|ensembl:ENSP00000304803 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nkrf_human(display_long)|uniprotkb:Transcription factor NRF(gene name synonym)|uniprotkb:Protein ITBA4(gene name synonym)|uniprotkb:NKRF(gene name)|psi-mi:NKRF(display_short)|uniprotkb:ITBA4(gene name synonym)|uniprotkb:NRF(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001166958.1|refseq:NP_001166959.1|refseq:NP_060014.2|refseq:XP_011529667.1|dip:DIP-34570N|ensembl:ENSG00000186416(gene)|ensembl:ENST00000304449(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000467(D111/G-patch)|interpro:IPR001374(Single-stranded nucleic acid binding R3H)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036867|mint:O15226|rcsb pdb:6SH6|rcsb pdb:6SH7|interpro:IPR034071 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:jH7qlOvuAHKsjuOyzDpBonpgtF09606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:A6NHQ2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880232|ensembl:ENSP00000473383|uniprotkb:R4GMW7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:fbll1_human(display_long)|uniprotkb:FBLL1(gene name)|psi-mi:FBLL1(display_short)|uniprotkb:Protein-glutamine methyltransferase(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000338333(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|ensembl:ENSG00000188573(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:SXuNpiRJofinc5yUsg+MIjFIeW09606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00159 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q06787 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:+iN/J/MbxTcRwgDezYseEDwLep49606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H0A0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P60660 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8IWJ2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1645320|uniprotkb:O15045|uniprotkb:Q4ZG46|uniprotkb:Q8TDH3|uniprotkb:Q9H2G8|uniprotkb:A6H8X8|intact:EBI-1645335|intact:EBI-28984280|ensembl:ENSP00000307939 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gcc2_human(display_long)|uniprotkb:GCC2(gene name)|psi-mi:GCC2(display_short)|uniprotkb:KIAA0336(gene name synonym)|uniprotkb:RANBP2L4(gene name synonym)|uniprotkb:185 kDa Golgi coiled-coil protein(gene name synonym)|uniprotkb:Ran-binding protein 2-like 4(gene name synonym)|uniprotkb:CTCL tumor antigen se1-1(gene name synonym)|uniprotkb:CLL-associated antigen KW-11(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-53(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_852118.1|refseq:XP_006712934.1|ensembl:ENSP00000307939|ensembl:ENST00000482325|ensembl:ENSP00000419969|ensembl:ENSG00000135968(gene)|ensembl:ENST00000309863(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0016020"(membrane)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034499"(late endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0070861"(regulation of protein exit from endoplasmic reticulum)|go:"GO:0071955"(recycling endosome to Golgi transport)|go:"GO:0090161"(Golgi ribbon formation)|interpro:IPR000237(GRIP)|interpro:IPR032023|rcsb pdb:3BBP|reactome:R-HSA-6811440 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:YeL/V7QABi3DbamH+qE6WfFLAco9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NPG3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880187|ensembl:ENSP00000262376|ensembl:ENSP00000379894|uniprotkb:B7Z6D3|uniprotkb:Q13079|uniprotkb:Q9P1P7|uniprotkb:D3DUE8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ubn1_human(display_long)|uniprotkb:UBN1(gene name)|psi-mi:UBN1(display_short)|uniprotkb:HIRA-binding protein(gene name synonym)|uniprotkb:Protein VT4(gene name synonym)|uniprotkb:Ubiquitously expressed nuclear protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000118900(gene)|ensembl:ENST00000262376(transcript)|ensembl:ENST00000396658(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026936|interpro:IPR026947|mint:Q9NPG3|rcsb pdb:4ZBJ|reactome:R-HSA-2559584|go:"GO:0005654"(nucleoplasm)|refseq:NP_001072982.1|refseq:XP_016878678.1|refseq:NP_001275585.1|ensembl:ENSP00000262376|ensembl:ENSP00000379894|ensembl:ENST00000590769|ensembl:ENSP00000468740 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:IT0lTmzNcbWFQVVD5DfATSqxjwg9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UQ26 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1756749|uniprotkb:O43413|uniprotkb:Q86XL9|uniprotkb:Q8IWV9|uniprotkb:Q8IWW1|uniprotkb:B3KX91|uniprotkb:F8WD47|intact:EBI-28973118 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rims2_human(display_long)|uniprotkb:RIMS2(gene name)|psi-mi:RIMS2(display_short)|uniprotkb:KIAA0751(gene name synonym)|uniprotkb:RAB3IP3(gene name synonym)|uniprotkb:RIM2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)|uniprotkb:Rab-3-interacting protein 3(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001269810.1|refseq:NP_001269811.1|ensembl:ENST00000262231|ensembl:ENSP00000262231|ensembl:ENSG00000176406|ensembl:ENST00000339750|ensembl:ENSP00000342051|ensembl:ENSP00000427018|ensembl:ENST00000507740|ensembl:ENSP00000423559|ensembl:ENST00000504942|refseq:NP_001093587.1|refseq:NP_055492.3|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|rcsb pdb:1V27|rcsb pdb:1WFG|interpro:IPR039032|interpro:IPR030631|interpro:IPR035892|interpro:IPR036034|interpro:IPR041282|interpro:IPR041489|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:r+m/eB+6yczGhwv4pxI6vzG/RHc9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P06396 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q14978 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y623 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2511704|ensembl:ENSP00000255381 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myh4_human(display_long)|uniprotkb:MYH4(gene name)|psi-mi:MYH4(display_short)|uniprotkb:Myosin heavy chain 4(gene name synonym)|uniprotkb:Myosin heavy chain 2b(gene name synonym)|uniprotkb:Myosin heavy chain IIb(gene name synonym)|uniprotkb:Myosin heavy chain, skeletal muscle, fetal(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000264424(gene)|ensembl:ENST00000255381(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0032982"(myosin filament)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0051015"(actin filament binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|go:"GO:0005859"(muscle myosin complex)|refseq:NP_060003.2|refseq:XP_016880165.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:7zD8Mcq4iGSoiy7hj6AyKDzesRQ9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:A7E2Y1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880253|ensembl:ENSP00000483640|uniprotkb:Q5JVW7|uniprotkb:Q6WG75|uniprotkb:Q6NT44|uniprotkb:Q9NWE2|uniprotkb:Q9P216|uniprotkb:Q6NT57|uniprotkb:Q96I57 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myh7b_human(display_long)|uniprotkb:MYH7B(gene name)|psi-mi:MYH7B(display_short)|uniprotkb:KIAA1512(gene name synonym)|uniprotkb:Antigen MLAA-21(gene name synonym)|uniprotkb:Myosin cardiac muscle beta chain(gene name synonym)|uniprotkb:Myosin heavy chain 7B, cardiac muscle beta isoform(gene name synonym)|uniprotkb:Slow A MYH14(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0032982"(myosin filament)|go:"GO:0051015"(actin filament binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:A7E2Y1|go:"GO:0005524"(ATP binding)|ensembl:ENSG00000078814(gene)|ensembl:ENST00000618182(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|refseq:NP_065935.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:HCH48jsSn7DEOwokRIJw+VHaKDo9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96KM6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1049952|uniprotkb:Q08AK9|uniprotkb:Q9ULM4|ensembl:ENSP00000358904 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:z512b_human(display_long)|uniprotkb:ZNF512B(gene name)|psi-mi:ZNF512B(display_short)|uniprotkb:KIAA1196(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_065764.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96KM6|rcsb pdb:2GQJ|reactome:R-HSA-9013424|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000196700(gene)|ensembl:ENST00000369888(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|refseq:XP_011527231.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:kdtiH1kX3fw2Si0UVegJb6AS+709606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y4W2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96QR8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880222|ensembl:ENSP00000379051|uniprotkb:A4D2L7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:purb_human(display_long)|uniprotkb:PURB(gene name)|psi-mi:PURB(display_short)|uniprotkb:Purine-rich element-binding protein B(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000146676(gene)|ensembl:ENST00000395699(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|mint:Q96QR8|go:"GO:0046332"(SMAD binding)|refseq:NP_150093.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:C29M3TyoXYI3mhCdaSsYC2kt8ek9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P07942 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-949174|ensembl:ENSP00000222399|uniprotkb:Q14D91 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lamb1_human(display_long)|uniprotkb:LAMB1(gene name)|psi-mi:LAMB1(display_short)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000091136(gene)|ensembl:ENST00000222399(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042476"(odontogenesis)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070831"(basement membrane assembly)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P07942|rcsb pdb:5XAU|rcsb pdb:7CEC|reactome:R-HSA-1474228|reactome:R-HSA-3000157|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-373760|reactome:R-HSA-381426|reactome:R-HSA-8874081|reactome:R-HSA-8957275|go:"GO:0043259"(laminin-10 complex)|reactome:R-HSA-9619665|refseq:NP_002282.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ZAg5y5cSIvyhPYPhe9BAHMnE1rs9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NYF8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-437804|ensembl:ENSP00000435210|uniprotkb:Q86WY0|uniprotkb:Q14673|uniprotkb:Q86WU6|uniprotkb:B7ZM58|uniprotkb:A2RU75|uniprotkb:E1P586 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:bclf1_human(display_long)|uniprotkb:BCLAF1 and THRAP3 family member 1(gene name synonym)|uniprotkb:BCLAF1(gene name)|psi-mi:BCLAF1(display_short)|uniprotkb:BTF(gene name synonym)|uniprotkb:KIAA0164(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000029363(gene)|ensembl:ENST00000531224(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR026668|interpro:IPR029199|mint:Q9NYF8|refseq:NP_001070908.1|refseq:NP_001070909.1|refseq:NP_055554.1|refseq:NP_001287967.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:v6qbjyjKVCv0B/olkjQfTPKWqBw9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UKN8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1237240|uniprotkb:Q5VZJ7|ensembl:ENSP00000361219 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tf3c4_human(display_long)|uniprotkb:GTF3C4(gene name)|psi-mi:GTF3C4(display_short)|uniprotkb:Transcription factor IIIC subunit delta(gene name synonym)|uniprotkb:TF3C-delta(gene name synonym)|uniprotkb:Transcription factor IIIC 90 kDa subunit(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_036336.2|ensembl:ENSG00000125484(gene)|ensembl:ENST00000372146(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR024761|interpro:IPR024764|interpro:IPR036322|interpro:IPR044230|mint:Q9UKN8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:OFldz80WMs7KQ59Of0rkkj80lyc9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9GZS1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-359458|uniprotkb:Q5VZT3|uniprotkb:Q8NBA9|uniprotkb:Q96L20|ensembl:ENSP00000367029|intact:EBI-21026140 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rpa49_human(display_long)|uniprotkb:POLR1E(gene name)|psi-mi:POLR1E(display_short)|uniprotkb:PAF53(gene name synonym)|uniprotkb:PRAF1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit E(gene name synonym)|uniprotkb:RNA polymerase I-associated factor 1(gene name synonym)|uniprotkb:RNA polymerase I-associated factor 53(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001269695.1|refseq:NP_071935.1|ensembl:ENSG00000137054(gene)|ensembl:ENST00000377798(transcript)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|mint:Q9GZS1|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|reactome:R-HSA-427413|refseq:XP_005251604.1|dip:DIP-27546N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3cidLGlybOTCIJGQ6xweDrvBBYM9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q2NL98 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2803134|uniprotkb:B3KW55|ensembl:ENSP00000343348 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:vmac_human(display_long)|uniprotkb:VMAC(gene name)|psi-mi:VMAC(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001017921.1|ensembl:ENSG00000187650(gene)|ensembl:ENST00000339485(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045098"(type III intermediate filament)|interpro:IPR038809|mint:Q2NL98 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uE3A2XhetBP92kP4nP8zhjNG0co9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q14966 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-742207|uniprotkb:B5MDV1|uniprotkb:Q53R34|uniprotkb:Q5XJ05|uniprotkb:Q68DP3|uniprotkb:Q6P2H2|uniprotkb:Q7Z3T7|uniprotkb:Q8NF92|uniprotkb:Q8TCA1|uniprotkb:Q9H2G1|uniprotkb:Q9NP37|uniprotkb:B7ZLD1|ensembl:ENSP00000264447|ensembl:ENSP00000386433|uniprotkb:A0A096LPH6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:zn638_human(display_long)|uniprotkb:ZNF638(gene name)|psi-mi:ZNF638(display_short)|uniprotkb:NP220(gene name synonym)|uniprotkb:ZFML(gene name synonym)|uniprotkb:Zinc finger matrin-like protein(gene name synonym)|uniprotkb:Nuclear protein 220(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se33-1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001014972.1|refseq:NP_055312.2|refseq:NP_001239541.1|refseq:NP_001239542.1|ensembl:ENSG00000075292(gene)|ensembl:ENST00000264447(transcript)|ensembl:ENST00000409544(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR022755|interpro:IPR033096|interpro:IPR035979|interpro:IPR036236|mint:Q14966|rcsb pdb:6SXW|reactome:R-HSA-381340|go:"GO:0003690"(double-stranded DNA binding)|ensembl:ENSP00000264447|ensembl:ENSP00000386433|ensembl:ENST00000410075|ensembl:ENSP00000485608|dip:DIP-42386N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:KkoO3Hgmx9CwI4LgVmk2ankakIY9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NPD3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-371823|ensembl:ENSP00000315476 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62829 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P38432 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-945751|uniprotkb:B2R931|ensembl:ENSP00000240316 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:coil_human(display_long)|uniprotkb:COIL(gene name)|psi-mi:COIL(display_short)|uniprotkb:CLN80(gene name synonym)|uniprotkb:p80-coilin(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004636.1|dip:DIP-38503N|ensembl:ENSG00000121058(gene)|ensembl:ENST00000240316(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR024822|interpro:IPR031722|mint:P38432 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:hd5p6AbyA/GYNEeca99Mdb41qM09606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q7Z406 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q5T280 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880213|ensembl:ENSP00000354812|uniprotkb:Q6PIJ1|uniprotkb:Q6PJV9|uniprotkb:Q6P469|uniprotkb:Q6PGP9|uniprotkb:Q0D2P6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ci114_human(display_long)|uniprotkb:SPOUT1(gene name)|psi-mi:SPOUT1(display_short)|uniprotkb:C9orf114(gene name synonym)|uniprotkb:Centromere protein 32(gene name synonym)|uniprotkb:Kinetochore-associated protein(gene name synonym)|uniprotkb:SPOUT domain-containing methyltransferase 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000198917(gene)|ensembl:ENST00000361256(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032259"(methylation)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035198"(miRNA binding)|go:"GO:0051301"(cell division)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0072686"(mitotic spindle)|interpro:IPR003750(Protein of unknown function DUF171)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR029026|interpro:IPR029028|rcsb pdb:4RG1|refseq:NP_057474.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:xsCr/8Iqdx4wJ6XweqC73CSia749606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62906 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q7Z4L5 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2851301|uniprotkb:Q53T84|uniprotkb:Q6PIF5|uniprotkb:A8MUZ3|uniprotkb:Q8NCN3|uniprotkb:Q9HAK8|uniprotkb:Q96MA4|uniprotkb:Q6P4A1|uniprotkb:Q3LIE4|ensembl:ENSP00000243344|ensembl:ENSP00000506276|ensembl:ENSP00000506400 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tt21b_human(display_long)|uniprotkb:TTC21B(gene name)|psi-mi:TTC21B(display_short)|uniprotkb:KIAA1992(gene name synonym)|uniprotkb:Nbla10696(orf name)|uniprotkb:IFT139(gene name synonym)|uniprotkb:Intraflagellar transport 139 homolog(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_079029.3|ensembl:ENSG00000123607(gene)|ensembl:ENST00000243344(transcript)|ensembl:ENST00000680888(transcript)|ensembl:ENST00000681952(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005929"(cilium)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0021591"(ventricular system development)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097499"(protein localization to non-motile cilium)|go:"GO:0097542"(ciliary tip)|go:"GO:1903999"(negative regulation of eating behavior)|go:"GO:1905799"(regulation of intraciliary retrograde transport)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040364|reactome:R-HSA-5610787|reactome:R-HSA-5620924 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:y1VB2y4oBho3fxf1gOl0LAz2u8o9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O60264 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P12036 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880271|uniprotkb:Q9UQ14|uniprotkb:Q9UJS7|uniprotkb:Q96HF8|uniprotkb:B4DYY4|ensembl:ENSP00000311997 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nfh_human(display_long)|uniprotkb:NEFH(gene name)|psi-mi:NEFH(display_short)|uniprotkb:KIAA0845(gene name synonym)|uniprotkb:NFH(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament triplet H protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_066554.2|ensembl:ENSG00000100285(gene)|ensembl:ENST00000310624(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005883"(neurofilament)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:TXMrn6SWBHIYQY1loZfVvMo9PtU9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00232 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62854 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H4L4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880236|ensembl:ENSP00000314029|ensembl:ENSP00000403712|uniprotkb:Q96PS4|uniprotkb:Q66K15|uniprotkb:Q86VS7|uniprotkb:Q9Y3W9 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:senp3_human(display_long)|uniprotkb:SENP3(gene name)|psi-mi:SENP3(display_short)|uniprotkb:SSP3(gene name synonym)|uniprotkb:SUSP3(gene name synonym)|uniprotkb:SUMO-1-specific protease 3(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP3(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000161956(gene)|ensembl:ENST00000321337(transcript)|ensembl:ENST00000429205(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR037945|interpro:IPR038765|mint:Q9H4L4|reactome:R-HSA-6791226|refseq:NP_056485.2|dip:DIP-47511N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:sE4k87ORoxSjBkbccPsXLYzuqII9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BXU1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880195|ensembl:ENSP00000348132|uniprotkb:B7WPP5|uniprotkb:Q6PCD3|uniprotkb:Q9BXH8|uniprotkb:B4DZ06|uniprotkb:C9J4F9 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:stk31_human(display_long)|uniprotkb:STK31(gene name)|psi-mi:STK31(display_short)|uniprotkb:SGK396(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NYD-SPK(gene name synonym)|uniprotkb:Sugen kinase 396(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000196335(gene)|ensembl:ENST00000355870(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002999(Tudor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR035437|mint:Q9BXU1|refseq:NP_113602.2|refseq:NP_116562.2|refseq:NP_001247433.1|refseq:NP_001247434.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:KC+aYcEcEHGINDcLf6qtz5EPiGg9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NW13 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2878099|ensembl:ENSP00000223073|uniprotkb:Q96CV3|uniprotkb:A4D100|uniprotkb:Q53H65|uniprotkb:B4DU52|uniprotkb:E9PDD9 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm28_human(display_long)|uniprotkb:RBM28(gene name)|psi-mi:RBM28(display_short)|uniprotkb:RNA-binding motif protein 28(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9NW13|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000106344(gene)|ensembl:ENST00000223073(transcript)|refseq:NP_001159607.1|refseq:NP_060547.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:yIPQX+d5YQpq3gpdtBilOXJcUsg9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P55795 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352823|ensembl:ENSP00000361927|uniprotkb:Q9HHA7|uniprotkb:A1L400 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hnrh2_human(display_long)|uniprotkb:HNRNPH2(gene name)|psi-mi:HNRNPH2(display_short)|uniprotkb:FTP3(gene name synonym)|uniprotkb:HNRPH2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)|uniprotkb:FTP-3(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000126945(gene)|ensembl:ENST00000316594(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P55795|rcsb pdb:1WEZ|rcsb pdb:1WG5|rcsb pdb:6DG1|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001027565.1|refseq:NP_062543.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:811j5syFsbk/QSaZv/ag9QsFUEQ9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P55060 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62249 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y5Q9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1054873|uniprotkb:Q4ZG48|uniprotkb:Q86XJ8|uniprotkb:Q8WX84|uniprotkb:Q96B44|uniprotkb:Q9H5I8|uniprotkb:Q9NT97|intact:EBI-1237212|ensembl:ENSP00000263956 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tf3c3_human(display_long)|uniprotkb:GTF3C3(gene name)|psi-mi:GTF3C3(display_short)|uniprotkb:Transcription factor IIIC subunit gamma(gene name synonym)|uniprotkb:Transcription factor IIIC 102 kDa subunit(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001193703.1|refseq:NP_036218.1|ensembl:ENSG00000119041(gene)|ensembl:ENST00000263956(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039340|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:cF53nd62xSXQfZerd7bdfB2KUgk9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H3S7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-724478|uniprotkb:Q7KZF8|uniprotkb:Q8N6Z5|uniprotkb:Q9BSR5|uniprotkb:Q9P257|uniprotkb:Q9UG03|uniprotkb:Q9UMZ4|uniprotkb:A8K0D7|ensembl:ENSP00000265562 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ptn23_human(display_long)|uniprotkb:His domain-containing protein tyrosine phosphatase(gene name synonym)|uniprotkb:Protein tyrosine phosphatase TD14(gene name synonym)|uniprotkb:PTPN23(gene name)|psi-mi:PTPN23(display_short)|uniprotkb:KIAA1471(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_056281.1|ensembl:ENSG00000076201(gene)|ensembl:ENST00000265562(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0060271"(cilium assembly)|go:"GO:0061357"(positive regulation of Wnt protein secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903387"(positive regulation of homophilic cell adhesion)|go:"GO:1903393"(positive regulation of adherens junction organization)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR004328(BRO1)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR025304|interpro:IPR029021|interpro:IPR038499|mint:Q9H3S7|rcsb pdb:5CRU|rcsb pdb:5CRV|rcsb pdb:5LM1|rcsb pdb:5LM2|rcsb pdb:5MJY|rcsb pdb:5MJZ|rcsb pdb:5MK0|rcsb pdb:5MK1|rcsb pdb:5MK2|rcsb pdb:5MK3|reactome:R-HSA-9008059|rcsb pdb:3RAU|refseq:NP_001291411.1|dip:DIP-29923N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:PeqzQLL4J4v9IMuHFBlb+1B4Ujw9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P56182 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P60709 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P49754 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2130459|uniprotkb:Q99851|uniprotkb:Q99852|uniprotkb:Q86TP8|uniprotkb:E9PF36|ensembl:ENSP00000309457 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:vps41_human(display_long)|uniprotkb:VPS41(gene name)|psi-mi:VPS41(display_short)|uniprotkb:S53(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055211.2|refseq:NP_542198.2|ensembl:ENSG00000006715(gene)|ensembl:ENST00000310301(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0008017"(microtubule binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010008"(endosome membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030897"(HOPS complex)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:1902501"(lysosomal HOPS complex)|go:"GO:1902774"(late endosome to lysosome transport)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016902(Vacuolar protein sorting-associated protein 41)|interpro:IPR036322 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ehH/zcBGZBo+HKWXQRxDgr0KcgI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q01780 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8TF72 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2622657|uniprotkb:Q9P247|uniprotkb:Q5QTQ3|uniprotkb:Q96IR9|uniprotkb:Q6ZRW3|ensembl:ENSP00000296043 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:shrm3_human(display_long)|uniprotkb:KIAA1481(gene name synonym)|uniprotkb:SHRML(gene name synonym)|uniprotkb:Shroom-related protein(gene name synonym)|uniprotkb:MSTP013(orf name)|uniprotkb:SHROOM3(gene name)|psi-mi:SHROOM3(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_065910.3|ensembl:ENSG00000138771(gene)|ensembl:ENST00000296043(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0002064"(epithelial cell development)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043296"(apical junction complex)|go:"GO:0043482"(cellular pigment accumulation)|go:"GO:0045176"(apical protein localization)|go:"GO:0051015"(actin filament binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR014799(Apx/shroom, ASD2)|interpro:IPR014800(Apx/shroom, ASD1)|interpro:IPR027685|interpro:IPR030494|interpro:IPR036034|mint:Q8TF72|rcsb pdb:6FBB|rcsb pdb:6FCP|ensembl:ENSP00000296043 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:0MpUunWh5c6Wwa8ep6BgurgU8e89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P18124 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UQ35 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1050142|uniprotkb:A6NKB9|uniprotkb:Q9UHA8|uniprotkb:Q9UQ36|uniprotkb:Q9UQ37|uniprotkb:Q9UQ38|uniprotkb:Q9UQ40|uniprotkb:O15038|uniprotkb:O94803|uniprotkb:Q6NSL3|uniprotkb:Q6PIM3|uniprotkb:Q6PK40|uniprotkb:Q8IW17|uniprotkb:Q96GY7|uniprotkb:Q9P0G1|uniprotkb:D3DU97|ensembl:ENSP00000301740 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:srrm2_human(display_long)|uniprotkb:Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa(gene name synonym)|uniprotkb:Splicing coactivator subunit SRm300(gene name synonym)|uniprotkb:300 kDa nuclear matrix antigen(gene name synonym)|uniprotkb:SRRM2(gene name)|psi-mi:SRRM2(display_short)|uniprotkb:KIAA0324(gene name synonym)|uniprotkb:SRL300(gene name synonym)|uniprotkb:SRM300(gene name synonym)|uniprotkb:HSPC075(orf name)|uniprotkb:Tax-responsive enhancer element-binding protein 803(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_057417.3|ensembl:ENSG00000167978(gene)|ensembl:ENST00000301740(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR013170(mRNA splicing factor, Cwf21)|interpro:IPR024945|mint:Q9UQ35|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7DVQ|reactome:R-HSA-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3yyPAOaCzKSCEg5guJSbq0MWrHI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NVC6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P46781 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UKX3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-373433|uniprotkb:O95252|intact:EBI-1059264|ensembl:ENSP00000252172|ensembl:ENSP00000404570|ensembl:ENSP00000480864|uniprotkb:Q9P0U8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myh13_human(display_long)|uniprotkb:MYH13(gene name)|psi-mi:MYH13(display_short)|uniprotkb:Myosin heavy chain 13(gene name synonym)|uniprotkb:Myosin heavy chain, skeletal muscle, extraocular(gene name synonym)|uniprotkb:Myosin heavy chain, skeletal muscle, laryngeal(gene name synonym)|uniprotkb:Superfast myosin(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_003793.2|ensembl:ENSG00000006788(gene)|ensembl:ENST00000252172(transcript)|ensembl:ENST00000418404(transcript)|ensembl:ENST00000621918(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0030016"(myofibril)|go:"GO:0032982"(myosin filament)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|interpro:IPR042702|mint:Q9UKX3|go:"GO:0005524"(ATP binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:BecPS6n8EFQ4BkUKAP7dreQFox09606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P98175 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|uniprotkb:A0A0A0MR66|ensembl:ENSP00000366829 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_005667.2|refseq:NP_690595.1|refseq:NP_001191397.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|ensembl:ENSG00000182872(gene)|ensembl:ENST00000377604(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q14684 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NRL2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-927511|uniprotkb:Q9NZ15|uniprotkb:Q9P065|uniprotkb:Q9UIG1|uniprotkb:Q9Y3V3|ensembl:ENSP00000353458|ensembl:ENSP00000371859 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:baz1a_human(display_long)|uniprotkb:BAZ1A(gene name)|psi-mi:BAZ1A(display_short)|uniprotkb:ACF1(gene name synonym)|uniprotkb:WCRF180(gene name synonym)|uniprotkb:HSPC317(orf name)|uniprotkb:ATP-utilizing chromatin assembly and remodeling factor 1(gene name synonym)|uniprotkb:ATP-dependent chromatin-remodeling protein(gene name synonym)|uniprotkb:Williams syndrome transcription factor-related chromatin-remodeling factor 180(gene name synonym)|uniprotkb:CHRAC subunit ACF1(gene name synonym)|uniprotkb:hWALp1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_038476.2|refseq:NP_872589.1|dip:DIP-36071N|ensembl:ENSG00000198604(gene)|ensembl:ENST00000360310(transcript)|ensembl:ENST00000382422(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008623"(CHRAC)|go:"GO:0016573"(histone acetylation)|go:"GO:0016590"(ACF complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013136(WSTF/Acf1/Cbp146)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037325|rcsb pdb:5UIY psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:1N6/uH2kUWs1/HdPhSI2a/UnbqI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y5Q8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001116295.1|refseq:NP_036219.2|ensembl:ENSG00000148308(gene)|ensembl:ENST00000372097(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001273638.1|dip:DIP-50823N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P57053 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880265|ensembl:ENSP00000481622|uniprotkb:A0AVF9|uniprotkb:Q5R2W0 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:h2bfs_human(display_long)|uniprotkb:H2BS1(gene name)|psi-mi:H2BS1(display_short)|uniprotkb:H2B.S histone 1(gene name synonym)|uniprotkb:H2BFS(gene name synonym)|uniprotkb:Histone H2B.s(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000234289(gene)|ensembl:ENST00000599962(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0021762"(substantia nigra development)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-427359|refseq:XP_006723981.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:x8Ryb6Tm0nfhcmsoTX5h5ZRsN7g9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P46013 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-876367|uniprotkb:Q5VWH2|ensembl:ENSP00000357643 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ki67_human(display_long)|uniprotkb:MKI67(gene name)|psi-mi:MKI67(display_short)|uniprotkb:Antigen identified by monoclonal antibody Ki-67(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001139438.1|refseq:NP_002408.3|dip:DIP-28132N|ensembl:ENSG00000148773(gene)|ensembl:ENST00000368654(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR012568(K167R)|interpro:IPR029334|mint:P46013|rcsb pdb:1R21|rcsb pdb:2AFF|rcsb pdb:5J28 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:kyrLLOv4HSqah1Y6HtzebG978Kw9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9P013 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2371709|uniprotkb:B2RC17|uniprotkb:Q05BV9|uniprotkb:Q05DM1|uniprotkb:Q9UI29|ensembl:ENSP00000475615 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cwc15_human(display_long)|uniprotkb:CWC15(gene name)|psi-mi:CWC15(display_short)|uniprotkb:C11orf5(gene name synonym)|uniprotkb:AD-002(orf name)|uniprotkb:HSPC148(orf name) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011541170.1|refseq:NP_057487.2|refseq:XP_016873405.1|ensembl:ENSG00000150316(gene)|ensembl:ENST00000279839(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006973(Cwf15/Cwc15 cell cycle control protein)|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Sq0ehGSKIEKx1X9xv4Nx0ZiqXhk9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62979 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P48552 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6ZT12 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2341096|uniprotkb:Q6ZSC2|uniprotkb:Q6ZR55|uniprotkb:Q8ND96|uniprotkb:B4DZR7|uniprotkb:Q8IVE7|uniprotkb:Q2KHN5|ensembl:ENSP00000272793 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ubr3_human(display_long)|uniprotkb:UBR3(gene name)|psi-mi:UBR3(display_short)|uniprotkb:KIAA2024(gene name synonym)|uniprotkb:ZNF650(gene name synonym)|uniprotkb:N-recognin-3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3-alpha-III(gene name synonym)|uniprotkb:Zinc finger protein 650(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR3(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_742067.3|ensembl:ENSG00000144357(gene)|ensembl:ENST00000272793(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001967"(suckling behavior)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071596"(ubiquitin-dependent protein catabolic process via the N-end rule pathway)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR039164|interpro:IPR044046 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:96hvp16/7G0ErwWa7lDanCpru5I9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P03372 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q02543 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-350523|ensembl:ENSP00000222247 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl18a_human(display_long)|uniprotkb:RPL18A(gene name)|psi-mi:RPL18A(display_short)|uniprotkb:Large ribosomal subunit protein eL20(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000971.1|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:Q02543|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|go:"GO:0097327"(response to antineoplastic agent)|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|ensembl:ENSG00000105640(gene)|ensembl:ENST00000222247(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6ZME|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:O9XdW7Let2GcJpJLVuUtatVVv1I9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96KR1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2513582|ensembl:ENSP00000265069|uniprotkb:Q9Y687|uniprotkb:Q6P5A3|uniprotkb:B2RNR5|uniprotkb:Q9H6V4|uniprotkb:Q3B7X5|uniprotkb:Q05C08|uniprotkb:Q9NTI1|uniprotkb:Q86UA0|intact:EBI-2560216 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:zfr_human(display_long)|uniprotkb:ZFR(gene name)|psi-mi:ZFR(display_short)|uniprotkb:M-phase phosphoprotein homolog(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000056097(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR006561(DZF)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR043519|mint:Q96KR1|ensembl:ENST00000265069(transcript)|refseq:NP_057191.2|ensembl:ENSP00000265069|dip:DIP-47293N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:UQQP+tkUcQYka9ez6rMv2F6FXFM9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P05388 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q969Q0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q86VM9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1045965|uniprotkb:Q96DG4|uniprotkb:Q96MP7|ensembl:ENSP00000301011 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:zch18_human(display_long)|uniprotkb:NHN1(gene name synonym)|uniprotkb:Nuclear protein NHN1(gene name synonym)|uniprotkb:ZC3H18(gene name)|psi-mi:ZC3H18(display_short) psi-mi:"MI:0029"(cosedimentation through density gradient) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880211|imex:IM-13781-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001281269.1|ensembl:ENST00000301011(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0050779"(RNA destabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|mint:Q86VM9|ensembl:ENSG00000158545(gene)|ensembl:ENSP00000301011|refseq:NP_653205.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2019/01/23 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:H9lST8OLyCpyi5AWYqFYskL0ezI9606 intact-crc:A99FC1ACF9A6C6A3|rigid:K/kSosxl8ODaO8j4Ry2r8sw3d+U false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q86U86 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-637807|uniprotkb:Q9H2T3|uniprotkb:Q9H2T4|uniprotkb:Q9H2T5|uniprotkb:Q9H301|uniprotkb:Q9H314|uniprotkb:A1L381|uniprotkb:A1L382|uniprotkb:A4FUJ7|uniprotkb:Q1RMD1|uniprotkb:Q1RMD2|uniprotkb:Q96MS2|ensembl:ENSP00000296302 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pb1_human(display_long)|uniprotkb:Polybromo-1D(gene name synonym)|uniprotkb:BRG1-associated factor 180(gene name synonym)|uniprotkb:PBRM1(gene name)|psi-mi:PBRM1(display_short)|uniprotkb:PB1(gene name synonym)|uniprotkb:BAF180(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060783.3|ensembl:ENSG00000163939(gene)|ensembl:ENST00000296302(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR018359|interpro:IPR036427|interpro:IPR036910|interpro:IPR037382|interpro:IPR037968|interpro:IPR043151|mint:Q86U86|rcsb pdb:2KTB|rcsb pdb:3G0J|rcsb pdb:3HMF|rcsb pdb:3IU5|rcsb pdb:3IU6|rcsb pdb:3K2J|rcsb pdb:3LJW|rcsb pdb:3MB4|rcsb pdb:3TLP|rcsb pdb:4Q0N|rcsb pdb:4Q0O|rcsb pdb:4Y03|rcsb pdb:5E7D|rcsb pdb:5FH6|rcsb pdb:5FH7|rcsb pdb:5FH8|rcsb pdb:5HRV|rcsb pdb:5HRW|rcsb pdb:5HRX|rcsb pdb:5II1|rcsb pdb:5II2|rcsb pdb:5IID|rcsb pdb:6OXB|rcsb pdb:6ZN6|rcsb pdb:6ZNV|rcsb pdb:6ZS3|rcsb pdb:6ZS4|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33045N|refseq:XP_016862237.1|refseq:XP_016862238.1|refseq:XP_016862239.1|refseq:XP_016862246.1|refseq:XP_016862247.1|refseq:NP_851385.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:nJp9kwLE9qxj6DcyEO8dUok6k/Q9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62277 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y3I0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6UN15 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P11142 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62081 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354360|uniprotkb:Q6IPH1|uniprotkb:P23821|uniprotkb:P24818|uniprotkb:Q57Z92|ensembl:ENSP00000385018|ensembl:ENSP00000385286|ensembl:ENSP00000495273|ensembl:ENSP00000496654|ensembl:ENSP00000496757 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs7_human(display_long)|uniprotkb:RPS7(gene name)|psi-mi:RPS7(display_short)|uniprotkb:Small ribosomal subunit protein eS7(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001002.1|ensembl:ENSG00000171863(gene)|ensembl:ENST00000403564(transcript)|ensembl:ENST00000406376(transcript)|ensembl:ENST00000462576(transcript)|ensembl:ENST00000645674(transcript)|ensembl:ENST00000646909(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62081|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6G4S psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:l4aG6I34lmzYhNapbdv2CAAwRwg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UJX4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-395994|uniprotkb:Q8N4H7|uniprotkb:Q9BQD4|uniprotkb:E9PFB2|ensembl:ENSP00000261819 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:apc5_human(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)|uniprotkb:Cyclosome subunit 5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_057321.2|refseq:NP_001131031.1|refseq:NP_001317418.1|dip:DIP-32945N|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000089053(gene)|ensembl:ENST00000261819(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR026000|interpro:IPR037679|mint:Q9UJX4|rcsb pdb:4UI9|rcsb pdb:5A31 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q86W42 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880668|ensembl:ENSP00000326531|uniprotkb:Q8NBR1|uniprotkb:B2RA85|uniprotkb:Q9BTV9 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:thoc6_human(display_long)|uniprotkb:THOC6(gene name)|psi-mi:THOC6(display_short)|uniprotkb:WDR58(gene name synonym)|uniprotkb:Functional spliceosome-associated protein 35(gene name synonym)|uniprotkb:WD repeat-containing protein 58(gene name synonym)|uniprotkb:PSEC0006(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000131652(gene)|ensembl:ENST00000326266(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0000347"(THO complex)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR042626|mint:Q86W42|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|refseq:NP_001135822.1|refseq:NP_077315.2|refseq:NP_001334632.1|refseq:NP_001334633.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:mmpU10uiZc1+MK8ntLeD+GCVIOM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BWC9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-711501|ensembl:ENSP00000309681|ensembl:ENSP00000465757|uniprotkb:Q99786|ensembl:ENSP00000466870|ensembl:ENSP00000468539|uniprotkb:B3KUF9|uniprotkb:D3K183 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cc106_human(display_long)|uniprotkb:CCDC106(gene name)|psi-mi:CCDC106(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000173581(gene)|ensembl:ENST00000308964(transcript)|ensembl:ENST00000586790(transcript)|ensembl:ENST00000588740(transcript)|ensembl:ENST00000591578(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR031591|refseq:NP_037433.2|refseq:XP_005258884.1|refseq:XP_005258885.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:i15R76tObPsPuullqYoTxebAIC09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O15144 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:v5OozQTt614rvrBBoUavbAzjgZ49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q12789 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-357956|uniprotkb:B2RP21|uniprotkb:Q12838|uniprotkb:Q6DKN9|uniprotkb:Q9Y4W9|ensembl:ENSP00000348510 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tf3c1_human(display_long)|uniprotkb:GTF3C1(gene name)|psi-mi:GTF3C1(display_short)|uniprotkb:Transcription factor IIIC subunit alpha(gene name synonym)|uniprotkb:TF3C-alpha(gene name synonym)|uniprotkb:Transcription factor IIIC 220 kDa subunit(gene name synonym)|uniprotkb:TFIIIC box B-binding subunit(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001511.2|refseq:NP_001273171.1|dip:DIP-38212N|ensembl:ENSG00000077235(gene)|ensembl:ENST00000356183(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009304"(tRNA transcription)|go:"GO:0016020"(membrane)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007309(B-block binding subunit of TFIIIC)|interpro:IPR035625|interpro:IPR044210|mint:Q12789|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:1celgxr5g9oKbPr0x1SvI6S7hNE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P60660 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9ULK4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q3BBV2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2863585|intact:EBI-28968706 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nbpf8_human(display_long)|uniprotkb:NBPF8(gene name)|psi-mi:NBPF8(display_short)|uniprotkb:NBPF8P(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 interpro:IPR010630(Protein of unknown function DUF1220)|go:"GO:0005737"(cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:MNZ5h3PahJhkjpbb8el5/n+HVDE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O75526 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2658146|uniprotkb:Q6PEZ2|uniprotkb:Q9NQU0|ensembl:ENSP00000304139 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rmxl2_human(display_long)|uniprotkb:RBMXL2(gene name)|psi-mi:RBMXL2(display_short)|uniprotkb:HNRNPGT(gene name synonym)|uniprotkb:Testis-specific heterogeneous nuclear ribonucleoprotein G-T(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055284.3|ensembl:ENSG00000170748(gene)|ensembl:ENST00000306904(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0017069"(snRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uzbkZSgcNAVZnLgeB4I6/u4FuAc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BVP2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-641642|uniprotkb:Q96SV6|uniprotkb:Q96SV7|uniprotkb:Q9UJY0|intact:EBI-2559594|intact:EBI-718302|uniprotkb:B2RDC1|uniprotkb:Q5PU80|intact:EBI-28973725|ensembl:ENSP00000395772 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gnl3_human(display_long)|uniprotkb:Nucleolar GTP-binding protein 3(gene name synonym)|uniprotkb:Nucleostemin(gene name synonym)|uniprotkb:E2-induced gene 3 protein(gene name synonym)|uniprotkb:Novel nucleolar protein 47(gene name synonym)|uniprotkb:GNL3(gene name)|psi-mi:GNL3(display_short)|uniprotkb:E2IG3(gene name synonym)|uniprotkb:NS(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000394799|ensembl:ENSP00000378278|ensembl:ENSP00000395772|refseq:NP_055181.3|refseq:NP_996561.1|refseq:NP_996562.1|ensembl:ENSG00000163938(gene)|ensembl:ENST00000418458(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0017145"(stem cell division)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030496"(midbody)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904816"(positive regulation of protein localization to chromosome, telomeric region)|interpro:IPR006073(GTP1/OBG)|interpro:IPR014813(GNL3L/Grn1 putative GTPase)|interpro:IPR027417|interpro:IPR030378|mint:Q9BVP2|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:c1DgvQoZ51edxvnCa6GFhfNRR7M9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O75369 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00515 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880585|ensembl:ENSP00000375829|uniprotkb:Q96GD8|uniprotkb:O95614 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lad1_human(display_long)|uniprotkb:LAD1(gene name)|psi-mi:LAD1(display_short)|uniprotkb:LAD(gene name synonym)|uniprotkb:Linear IgA disease antigen(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000391967(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017404(Ladinin 1)|mint:O00515|ensembl:ENSG00000159166(gene)|refseq:NP_005549.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:C58/NEfIlDj38lGEIsWtqBNuSis9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92536 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880595|ensembl:ENSP00000219343|ensembl:ENSP00000455064|uniprotkb:Q68DS4|uniprotkb:Q7L1N3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ylat2_human(display_long)|uniprotkb:SLC7A6(gene name)|psi-mi:SLC7A6(display_short)|uniprotkb:KIAA0245(gene name synonym)|uniprotkb:Cationic amino acid transporter, y+ system(gene name synonym)|uniprotkb:Solute carrier family 7 member 6(gene name synonym)|uniprotkb:"y(+)L-type amino acid transporter 2"(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000219343(transcript)|ensembl:ENST00000566454(transcript)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015174"(basic amino acid transmembrane transporter activity)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015822"(ornithine transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1990822"(basic amino acid transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|reactome:R-HSA-210991|reactome:R-HSA-352230|ensembl:ENSG00000103064(gene)|refseq:XP_011521735.1|refseq:XP_011521736.1|refseq:XP_011521740.1|refseq:NP_001070253.1|refseq:NP_003974.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:l/KOJTuDkxlcf2PZ/+7orBGtbLg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y399 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880048|intact:EBI-28977422|ensembl:ENSP00000241600|ensembl:ENSP00000360850|uniprotkb:Q5T899|uniprotkb:Q9BSQ4 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt02_human(display_long)|uniprotkb:MRPS2(gene name)|psi-mi:MRPS2(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:CGI-91(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6RW5|ensembl:ENST00000241600(transcript)|ensembl:ENST00000371785(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0061668"(mitochondrial ribosome assembly)|ensembl:ENSG00000122140(gene)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|mint:Q9Y399|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|ensembl:ENSP00000241600|ensembl:ENSP00000360850|refseq:NP_057118.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:tlWj8Un0CmbnBQtZMYlJpvIpc/09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q13439 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1037845|uniprotkb:Q13270|uniprotkb:Q13654|uniprotkb:Q14436|uniprotkb:F8W8Q7|uniprotkb:Q59EW8|ensembl:ENSP00000354486 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:goga4_human(display_long)|uniprotkb:GOLGA4(gene name)|psi-mi:GOLGA4(display_short)|uniprotkb:Trans-Golgi p230(gene name synonym)|uniprotkb:256 kDa golgin(gene name synonym)|uniprotkb:Golgin-245(gene name synonym)|uniprotkb:Protein 72.1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001166184.1|refseq:NP_002069.2|ensembl:ENSG00000144674(gene)|ensembl:ENST00000361924(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000237(GRIP)|rcsb pdb:1R4A|rcsb pdb:1UPT|reactome:R-HSA-6811440|reactome:R-HSA-9673768 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:iRvTCfQleDllP1zq0dlAVyX58JU9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P50416 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2817330|uniprotkb:Q9BWK0|uniprotkb:Q8TCU0|ensembl:ENSP00000265641|ensembl:ENSP00000446108 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cpt1a_human(display_long)|uniprotkb:CPT1A(gene name)|psi-mi:CPT1A(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine O-palmitoyltransferase I, liver isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001027017.1|refseq:NP_001867.2|refseq:XP_016872709.1|ensembl:ENSG00000110090(gene)|ensembl:ENST00000265641(transcript)|ensembl:ENST00000539743(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0045471"(response to ethanol)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097421"(liver regeneration)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|mint:P50416|rcsb pdb:2LE3|reactome:R-HSA-1368082|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-5362517 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:fmB4d9VHyWPyV0uTf00NkOr/fM49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92621 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1045046|uniprotkb:Q86YC1|uniprotkb:A6H8X3|ensembl:ENSP00000285968 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nu205_human(display_long)|uniprotkb:Nucleoporin Nup205(gene name synonym)|uniprotkb:205 kDa nucleoporin(gene name synonym)|uniprotkb:NUP205(gene name)|psi-mi:NUP205(display_short)|uniprotkb:C7orf14(gene name synonym)|uniprotkb:KIAA0225(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000155561(gene)|ensembl:ENST00000285968(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0044611"(nuclear pore inner ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|interpro:IPR021827|mint:Q92621|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:NP_055950.1|refseq:NP_001316363.1|dip:DIP-44021N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:5lulE2tOZ4V1UZPwkEvOo9reZWE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00148 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q13042 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-994830|uniprotkb:Q96AE6|uniprotkb:Q9Y564|uniprotkb:A2A365|uniprotkb:Q5T8C8|ensembl:ENSP00000348554|ensembl:ENSP00000353549|uniprotkb:Q7Z651 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cdc16_human(display_long)|uniprotkb:ANAPC6(gene name synonym)|uniprotkb:CDC16 homolog(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 6(gene name synonym)|uniprotkb:Cyclosome subunit 6(gene name synonym)|uniprotkb:CDC16(gene name)|psi-mi:CDC16(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001072113.1|refseq:NP_003894.3|reactome:R-HSA-2559582|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|rcsb pdb:5L9T|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|rcsb pdb:5L9U|go:"GO:0016567"(protein ubiquitination)|rcsb pdb:5LCW|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0072686"(mitotic spindle)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:6Q6G|interpro:IPR019734|rcsb pdb:3HYM|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:4UI9|rcsb pdb:6TNT|reactome:R-HSA-141430|rcsb pdb:5A31|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|reactome:R-HSA-69017|reactome:R-HSA-2467813|reactome:R-HSA-179409|ensembl:ENSG00000130177(gene)|ensembl:ENST00000356221(transcript)|ensembl:ENST00000360383(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|refseq:NP_001305446.1|refseq:NP_001305447.1|refseq:NP_001317030.1|refseq:NP_001317033.1|refseq:NP_001317034.1|refseq:XP_016876322.1|dip:DIP-36423N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:AAG0s18JHrn+M5dG7T/N6t0Y97w9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O94776 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BTT6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-713489|uniprotkb:Q9HAC0|uniprotkb:Q9NVF1|ensembl:ENSP00000359925|uniprotkb:Q5TGN3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lrrc1_human(display_long)|uniprotkb:LAP and no PDZ protein(gene name synonym)|uniprotkb:LANO adapter protein(gene name synonym)|uniprotkb:LRRC1(gene name)|psi-mi:LRRC1(display_short)|uniprotkb:LANO(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000137269(gene)|ensembl:ENST00000370888(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|reactome:R-HSA-9696270|refseq:NP_060684.4|refseq:XP_011513028.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:FJ/8+gehIT2j2bJ8gYpkDht+//I9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P18621 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-726937|uniprotkb:Q6NZ54|uniprotkb:Q7M4M5|uniprotkb:Q3KQW2|uniprotkb:B2R4H3|uniprotkb:B4E3C2|uniprotkb:B5ME31|uniprotkb:J3QL51|ensembl:ENSP00000462023|ensembl:ENSP00000462385|ensembl:ENSP00000463842|ensembl:ENSP00000480555|ensembl:ENSP00000482577 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl17_human(display_long)|uniprotkb:60S ribosomal protein L23(gene name synonym)|uniprotkb:PD-1(gene name synonym)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short)|uniprotkb:Large ribosomal subunit protein uL22(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000976.1|refseq:NP_001030178.1|refseq:NP_001186269.1|refseq:NP_001186270.1|refseq:NP_001186271.1|refseq:NP_001186272.1|refseq:NP_001186273.1|refseq:NP_001186274.1|ensembl:ENSG00000265681(gene)|ensembl:ENST00000579248(transcript)|ensembl:ENST00000579408(transcript)|ensembl:ENST00000580261(transcript)|ensembl:ENST00000618613(transcript)|ensembl:ENST00000618619(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394|mint:P18621|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:/i0W3WoeFakz+8R/YMYf2JQZytI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8IX12 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-356265|ensembl:ENSP00000265872|uniprotkb:A0JLT7|uniprotkb:A1L4P7|uniprotkb:A8K9D4|uniprotkb:B4DNP8|uniprotkb:B4DRK8|uniprotkb:Q5EBM3|uniprotkb:Q32NE3|uniprotkb:Q5VUP6|uniprotkb:Q6PIZ0|uniprotkb:Q6X935|uniprotkb:Q9H8N4|uniprotkb:Q9NVA7|uniprotkb:Q9NVQ0|uniprotkb:Q9NWM6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ccar1_human(display_long)|uniprotkb:CCAR1(gene name)|psi-mi:CCAR1(display_short)|uniprotkb:CARP1(gene name synonym)|uniprotkb:DIS(gene name synonym)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Death inducer with SAP domain(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000060339(gene)|ensembl:ENST00000265872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8IX12|reactome:R-HSA-72163|refseq:NP_060707.2|refseq:NP_001269888.1|refseq:NP_001269889.1|dip:DIP-27607N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:YnZve7StC4kAO8raUbp8T02jpe09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P03372 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-78473|uniprotkb:Q6MZQ9|ensembl:ENSP00000387500|ensembl:ENSP00000342630|ensembl:ENSP00000206249|ensembl:ENSP00000405330|uniprotkb:Q13511|uniprotkb:Q14276|uniprotkb:Q9NU51|uniprotkb:Q9UDZ7|uniprotkb:Q9UIS7|intact:EBI-28988800|uniprotkb:Q5T5H7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:esr1_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short)|uniprotkb:ESR(gene name synonym)|uniprotkb:NR3A1(gene name synonym)|uniprotkb:Estradiol receptor(gene name synonym)|uniprotkb:ER-alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000091831(gene)|ensembl:ENST00000206249(transcript)|ensembl:ENST00000338799(transcript)|ensembl:ENST00000440973(transcript)|ensembl:ENST00000443427(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|refseq:NP_000116.2|refseq:NP_001116212.1|refseq:NP_001116213.1|refseq:NP_001116214.1|refseq:XP_011533845.1|refseq:XP_011533846.1|refseq:XP_011533847.1|refseq:XP_006715438.1|ensembl:ENSP00000206249|ensembl:ENSP00000342630|ensembl:ENSP00000405330|ensembl:ENSP00000387500|refseq:NP_001278159.1|refseq:NP_001278170.1|refseq:NP_001315029.1|refseq:XP_016865865.1|refseq:XP_016865866.1|refseq:XP_016865867.1|refseq:XP_016865868.1|refseq:XP_016865869.1|refseq:XP_016865870.1|dip:DIP-5965N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001547"(antral ovarian follicle growth)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0035327"|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0060065"(uterus development)|go:"GO:0060068"(vagina development)|go:"GO:0060523"(prostate epithelial cord elongation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR024178|interpro:IPR024736|interpro:IPR035500|mint:P03372|rcsb pdb:1A52|rcsb pdb:1AKF|rcsb pdb:1ERE|rcsb pdb:1ERR|rcsb pdb:1G50|rcsb pdb:1GWQ|rcsb pdb:1GWR|rcsb pdb:1HCP|rcsb pdb:1HCQ|rcsb pdb:1L2I|rcsb pdb:1PCG|rcsb pdb:1QKT|rcsb pdb:1QKU|rcsb pdb:1R5K|rcsb pdb:1SJ0|rcsb pdb:1UOM|rcsb pdb:1X7E|rcsb pdb:1X7R|rcsb pdb:1XP1|rcsb pdb:1XP6|rcsb pdb:1XP9|rcsb pdb:1XPC|rcsb pdb:1XQC|rcsb pdb:1YIM|rcsb pdb:1YIN|rcsb pdb:1ZKY|rcsb pdb:2AYR|rcsb pdb:2B1V|rcsb pdb:2B1Z|rcsb pdb:2B23|rcsb pdb:2BJ4|rcsb pdb:2FAI|rcsb pdb:2G44|rcsb pdb:2G5O|rcsb pdb:2I0J|rcsb pdb:2IOG|rcsb pdb:2IOK|rcsb pdb:2JF9|rcsb pdb:2JFA|rcsb pdb:2LLO|rcsb pdb:2LLQ|rcsb pdb:2OCF|rcsb pdb:2OUZ|rcsb pdb:2P15|rcsb pdb:2POG|rcsb pdb:2Q6J|rcsb pdb:2Q70|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QE4|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QXS|rcsb pdb:2QZO|rcsb pdb:2R6W|rcsb pdb:2R6Y|rcsb pdb:2YAT|rcsb pdb:2YJA|rcsb pdb:3DT3|rcsb pdb:3ERD|rcsb pdb:3ERT|rcsb pdb:3HLV|rcsb pdb:3HM1|rcsb pdb:3L03|rcsb pdb:3OS8|rcsb pdb:3OS9|rcsb pdb:3OSA|rcsb pdb:3Q95|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUC|rcsb pdb:3UUD|rcsb pdb:4AA6|rcsb pdb:4DMA|rcsb pdb:4IU7|rcsb pdb:4IUI|rcsb pdb:4IV2|rcsb pdb:4IV4|rcsb pdb:4IVW|rcsb pdb:4IVY|rcsb pdb:4IW6|rcsb pdb:4IW8|rcsb pdb:4IWC|rcsb pdb:4IWF|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4O6F|rcsb pdb:4PP6|rcsb pdb:4PPP|rcsb pdb:4PPS|rcsb pdb:4PXM|rcsb pdb:4Q13|rcsb pdb:4Q50|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4XI3|rcsb pdb:4ZN7|rcsb pdb:4ZN9|rcsb pdb:4ZNH|rcsb pdb:4ZNS|rcsb pdb:4ZNT|rcsb pdb:4ZNU|rcsb pdb:4ZNV|rcsb pdb:4ZNW|rcsb pdb:5AAU|rcsb pdb:5AAV|rcsb pdb:5ACC|rcsb pdb:5AK2|rcsb pdb:5DI7|rcsb pdb:5DID|rcsb pdb:5DIE|rcsb pdb:5DIG|rcsb pdb:5DK9|rcsb pdb:5DKB|rcsb pdb:5DKE|rcsb pdb:5DKG|rcsb pdb:5DKS|rcsb pdb:5DL4|rcsb pdb:5DLR|rcsb pdb:5DMC|rcsb pdb:5DMF|rcsb pdb:5DP0|rcsb pdb:5DRJ|rcsb pdb:5DRM|rcsb pdb:5DTV|rcsb pdb:5DU5|rcsb pdb:5DUE|rcsb pdb:5DUG|rcsb pdb:5DUH|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:5DVS|rcsb pdb:5DVV|rcsb pdb:5DWE|rcsb pdb:5DWG|rcsb pdb:5DWI|rcsb pdb:5DWJ|rcsb pdb:5DX3|rcsb pdb:5DXB|rcsb pdb:5DXE|rcsb pdb:5DXG|rcsb pdb:5DXK|rcsb pdb:5DXM|rcsb pdb:5DXQ|rcsb pdb:5DXR|rcsb pdb:5DY8|rcsb pdb:5DYB|rcsb pdb:5DYD|rcsb pdb:5DZ0|rcsb pdb:5DZ1|rcsb pdb:5DZ3|rcsb pdb:5DZH|rcsb pdb:5DZI|rcsb pdb:5E0W|rcsb pdb:5E0X|rcsb pdb:5E14|rcsb pdb:5E15|rcsb pdb:5E19|rcsb pdb:5E1C|rcsb pdb:5EGV|rcsb pdb:5EHJ|rcsb pdb:5EI1|rcsb pdb:5EIT|rcsb pdb:5FQP|rcsb pdb:5FQR|rcsb pdb:5FQS|rcsb pdb:5FQT|rcsb pdb:5FQV|rcsb pdb:5GS4|rcsb pdb:5GTR|rcsb pdb:5HYR|rcsb pdb:5JMM|rcsb pdb:5KCC|rcsb pdb:5KCD|rcsb pdb:5KCE|rcsb pdb:5KCF|rcsb pdb:5KCT|rcsb pdb:5KCU|rcsb pdb:5KCW|rcsb pdb:5KD9|rcsb pdb:5KR9|rcsb pdb:5KRA|rcsb pdb:5KRC|rcsb pdb:5KRF|rcsb pdb:5KRH|rcsb pdb:5KRI|rcsb pdb:5KRJ|rcsb pdb:5KRK|rcsb pdb:5KRL|rcsb pdb:5KRM|rcsb pdb:5KRO|rcsb pdb:5N10|rcsb pdb:5T0X|rcsb pdb:5T1Z|rcsb pdb:5T92|rcsb pdb:5T97|rcsb pdb:5TLD|rcsb pdb:5TLF|rcsb pdb:5TLG|rcsb pdb:5TLL|rcsb pdb:5TLM|rcsb pdb:5TLO|rcsb pdb:5TLP|rcsb pdb:5TLT|rcsb pdb:5TLU|rcsb pdb:5TLV|rcsb pdb:5TLX|rcsb pdb:5TLY|rcsb pdb:5TM1|rcsb pdb:5TM2|rcsb pdb:5TM3|rcsb pdb:5TM4|rcsb pdb:5TM5|rcsb pdb:5TM6|rcsb pdb:5TM7|rcsb pdb:5TM8|rcsb pdb:5TM9|rcsb pdb:5TML|rcsb pdb:5TMM|rcsb pdb:5TMO|rcsb pdb:5TMQ|rcsb pdb:5TMR|rcsb pdb:5TMS|rcsb pdb:5TMT|rcsb pdb:5TMU|rcsb pdb:5TMV|rcsb pdb:5TMW|rcsb pdb:5TMZ|rcsb pdb:5TN1|rcsb pdb:5TN3|rcsb pdb:5TN4|rcsb pdb:5TN5|rcsb pdb:5TN6|rcsb pdb:5TN7|rcsb pdb:5TN8|rcsb pdb:5TN9|rcsb pdb:5TNB|rcsb pdb:5U2B|rcsb pdb:5U2D|rcsb pdb:5UFW|rcsb pdb:5DXP|rcsb pdb:5UFX|rcsb pdb:5W9C|rcsb pdb:5W9D|rcsb pdb:5WGD|rcsb pdb:5WGQ|rcsb pdb:6B0F|rcsb pdb:6C42|rcsb pdb:6CBZ|rcsb pdb:6CHW|rcsb pdb:6CHZ|rcsb pdb:6CZN|rcsb pdb:6D0F|rcsb pdb:6DF6|rcsb pdb:6DFN|rcsb pdb:6HHP|rcsb pdb:6HKF|rcsb pdb:6HMU|rcsb pdb:6IAR|rcsb pdb:6OWC|rcsb pdb:6PET|rcsb pdb:6PFM|rcsb pdb:6PIT|rcsb pdb:6PSJ|rcsb pdb:6SBO|rcsb pdb:6SQ0|rcsb pdb:6SUO|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6V87|rcsb pdb:6V8T|rcsb pdb:6VGH|rcsb pdb:6VIG|rcsb pdb:6VJ1|rcsb pdb:6VJD|rcsb pdb:6VMU|rcsb pdb:6VPF|rcsb pdb:6VPK|rcsb pdb:6VVP|rcsb pdb:6WOK|rcsb pdb:6ZOQ|rcsb pdb:6ZOR|rcsb pdb:6ZOS|rcsb pdb:7JHD|rcsb pdb:7KBS|rcsb pdb:7KCA|rcsb pdb:7KCD|rcsb pdb:7MSA|rcsb pdb:7NFW|reactome:R-HSA-1251985|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-4090294|reactome:R-HSA-5689896|reactome:R-HSA-6811558|reactome:R-HSA-8866910|reactome:R-HSA-8931987|reactome:R-HSA-8939211|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-9009391|reactome:R-HSA-9018519|rcsb pdb:6HKB psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:T8sQVUNhd5AfJXfL0mjq9TA/C/o9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H7B2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1051960|uniprotkb:Q8N4A1|uniprotkb:Q5VXN1|ensembl:ENSP00000402338 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rpf2_human(display_long)|uniprotkb:RPF2(gene name)|psi-mi:RPF2(display_short)|uniprotkb:BXDC1(gene name synonym)|uniprotkb:Ribosome biogenesis protein RPF2 homolog(gene name synonym)|uniprotkb:Brix domain-containing protein 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_115570.1|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR007109(Brix)|interpro:IPR039770|mint:Q9H7B2|ensembl:ENSG00000197498(gene)|ensembl:ENST00000441448(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)") psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:CXU4CHQmcrISLS8GDIwEMGhiaQI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9P2E9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2371806|uniprotkb:A2A2S6|uniprotkb:A6NCN6|uniprotkb:O75300|uniprotkb:O75301|uniprotkb:Q5W165|uniprotkb:Q96SB2|uniprotkb:Q9BWP1|uniprotkb:Q9H476|uniprotkb:A0A0A0MRV0|intact:EBI-28985482|ensembl:ENSP00000246043|ensembl:ENSP00000367044 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rrbp1_human(display_long)|uniprotkb:RRBP1(gene name)|psi-mi:RRBP1(display_short)|uniprotkb:KIAA1398(gene name synonym)|uniprotkb:Ribosome receptor protein(gene name synonym)|uniprotkb:180 kDa ribosome receptor homolog(gene name synonym)|uniprotkb:ES/130-related protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001036041.1|refseq:NP_004578.2|ensembl:ENSP00000246043|ensembl:ENST00000360807|ensembl:ENSP00000354045|ensembl:ENST00000377807|ensembl:ENSP00000367038|ensembl:ENSP00000367044|ensembl:ENSG00000125844(gene)|ensembl:ENST00000246043(transcript)|ensembl:ENST00000377813(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR040248|mint:Q9P2E9 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uOiVzIAM5bsSl2s1BSIfnUtZ3Ms9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P06396 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351506|uniprotkb:Q8WVV7|ensembl:ENSP00000362924|uniprotkb:Q5T0I2|uniprotkb:A8MUD1|uniprotkb:B7Z373|uniprotkb:A2A418|uniprotkb:A8MYN7|uniprotkb:B7Z5V1|uniprotkb:F5H1A8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gels_human(display_long)|uniprotkb:GSN(gene name)|psi-mi:GSN(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:AGEL(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000168.1|refseq:NP_001121134.1|refseq:NP_001121136.1|refseq:NP_001121137.1|refseq:NP_001121138.1|refseq:NP_001121139.1|refseq:NP_937895.1|refseq:XP_011516888.1|refseq:XP_011516889.1|refseq:XP_011516890.1|refseq:XP_011516891.1|refseq:XP_011516892.1|refseq:XP_011516893.1|refseq:XP_011516894.1|refseq:XP_011516895.1|ensembl:ENSG00000148180(gene)|ensembl:ENST00000373818(transcript)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P06396|rcsb pdb:1C0F|rcsb pdb:1C0G|rcsb pdb:1D4X|rcsb pdb:1DEJ|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1KCQ|rcsb pdb:1MDU|rcsb pdb:1NLV|rcsb pdb:1NM1|rcsb pdb:1NMD|rcsb pdb:1P8X|rcsb pdb:1SOL|rcsb pdb:1T44|rcsb pdb:1YAG|rcsb pdb:1YVN|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FH1|rcsb pdb:2FH2|rcsb pdb:2FH3|rcsb pdb:2FH4|rcsb pdb:3A5L|rcsb pdb:3A5M|rcsb pdb:3A5N|rcsb pdb:3A5O|rcsb pdb:3CI5|rcsb pdb:3CIP|rcsb pdb:3CJB|rcsb pdb:3CJC|rcsb pdb:3FFK|rcsb pdb:3FFN|rcsb pdb:3TU5|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4S10|rcsb pdb:4Z94|rcsb pdb:5DD2|rcsb pdb:5FAE|rcsb pdb:5FAF|rcsb pdb:5H3M|rcsb pdb:5H3N|rcsb pdb:5O2Z|rcsb pdb:5UBO|rcsb pdb:5ZZ0|rcsb pdb:6H1F|rcsb pdb:6JCO|rcsb pdb:6JEG|rcsb pdb:6JEH|rcsb pdb:6LJE|rcsb pdb:6LJF|rcsb pdb:6Q9R|rcsb pdb:6Q9Z|rcsb pdb:6QBF|rcsb pdb:1P8Z|rcsb pdb:6QW3|reactome:R-HSA-264870|reactome:R-HSA-6798695|reactome:R-HSA-9662361|reactome:R-HSA-977225|refseq:NP_001244958.1|refseq:NP_001244959.1|refseq:NP_001121135.2|refseq:XP_005252000.1|refseq:XP_005252001.1|refseq:XP_005252002.1|refseq:XP_006717142.1|refseq:XP_016870135.1|refseq:XP_016870136.1|refseq:XP_016870137.1|dip:DIP-2196N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uACf9A+H6LAOAZSMGYqeDwUL1Mc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92731 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9P013 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2371709|uniprotkb:B2RC17|uniprotkb:Q05BV9|uniprotkb:Q05DM1|uniprotkb:Q9UI29|ensembl:ENSP00000475615 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cwc15_human(display_long)|uniprotkb:CWC15(gene name)|psi-mi:CWC15(display_short)|uniprotkb:C11orf5(gene name synonym)|uniprotkb:AD-002(orf name)|uniprotkb:HSPC148(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011541170.1|refseq:NP_057487.2|refseq:XP_016873405.1|ensembl:ENSG00000150316(gene)|ensembl:ENST00000279839(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR006973(Cwf15/Cwc15 cell cycle control protein)|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Sq0ehGSKIEKx1X9xv4Nx0ZiqXhk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q08378 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-355782|uniprotkb:O43241|uniprotkb:Q6P9C7|uniprotkb:Q86XW3|uniprotkb:Q8TDA9|uniprotkb:Q8WZA3|uniprotkb:A5PKX6|intact:EBI-28985028|ensembl:ENSP00000204726|ensembl:ENSP00000410378 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:goga3_human(display_long)|uniprotkb:GOLGA3(gene name)|psi-mi:GOLGA3(display_short)|uniprotkb:Golgin-160(gene name synonym)|uniprotkb:Golgi complex-associated protein of 170 kDa(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001166028.1|refseq:NP_005886.2|ensembl:ENSP00000204726|ensembl:ENSP00000410378|ensembl:ENST00000456883|ensembl:ENSP00000409303|ensembl:ENST00000545875|ensembl:ENSP00000442603|ensembl:ENSG00000090615(gene)|ensembl:ENST00000204726(transcript)|ensembl:ENST00000450791(transcript)|go:"GO:0045296"(cadherin binding)|go:"GO:0090498"(extrinsic component of Golgi membrane)|interpro:IPR033288|mint:Q08378|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9696270|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|refseq:XP_006719799.1|refseq:XP_006719800.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:7AjSzX3sUzfKpZkvdKDM0L//zYM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62910 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-438408|ensembl:ENSP00000380156|ensembl:ENSP00000380158|ensembl:ENSP00000388674|ensembl:ENSP00000416429|uniprotkb:P02433|uniprotkb:B2R4Q3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl32_human(display_long)|uniprotkb:RPL32(gene name)|psi-mi:RPL32(display_short)|uniprotkb:Large ribosomal subunit protein eL32(gene name synonym)|uniprotkb:PP9932(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000144713(gene)|ensembl:ENST00000396953(transcript)|ensembl:ENST00000396957(transcript)|ensembl:ENST00000429711(transcript)|ensembl:ENST00000435983(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR001515(Ribosomal protein L32e)|interpro:IPR018263|interpro:IPR036351|mint:P62910|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000985.1|refseq:NP_001007074.1|refseq:NP_001007075.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:8Yhph2ETzWYd07yJcq1cVqsSRjo9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P24386 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2515129|ensembl:ENSP00000350386|uniprotkb:O43732|uniprotkb:A1L4D2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rae1_human(display_long)|uniprotkb:CHM(gene name)|psi-mi:CHM(display_short)|uniprotkb:REP1(gene name synonym)|uniprotkb:TCD(gene name synonym)|uniprotkb:Rab escort protein 1(gene name synonym)|uniprotkb:TCD protein(gene name synonym)|uniprotkb:Choroideremia protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000188419(gene)|ensembl:ENST00000357749(transcript)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005968"(Rab-protein geranylgeranyltransferase complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0031267"(small GTPase binding)|interpro:IPR001738("Rab escort (choroideraemia) protein")|interpro:IPR018203|interpro:IPR036188|reactome:R-HSA-6803205|reactome:R-HSA-8873719|reactome:R-HSA-8876198|go:"GO:0016192"(vesicle-mediated transport)|refseq:NP_001307888.1|refseq:NP_000381.1|refseq:NP_001138886.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:lLHJ/D4ljKMp+kSHMHu9RUTdcps9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NZB2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1171960|uniprotkb:A6NGU0|uniprotkb:O60649|uniprotkb:Q14688|uniprotkb:Q4VXF4|uniprotkb:Q4VXF5|uniprotkb:Q4VXG2|uniprotkb:Q96I21|uniprotkb:Q9NZB1|uniprotkb:C4AMC6|uniprotkb:Q86V69|intact:EBI-2560129|ensembl:ENSP00000277165 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:f120a_human(display_long)|uniprotkb:Protein FAM120A(gene name synonym)|uniprotkb:FAM120A(gene name)|psi-mi:FAM120A(display_short)|uniprotkb:C9orf10(gene name synonym)|uniprotkb:KIAA0183(gene name synonym)|uniprotkb:OSSA(gene name synonym)|uniprotkb:Oxidative stress-associated Src activator(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055427.2|refseq:XP_011516714.1|refseq:NP_001273651.1|refseq:NP_001273652.1|refseq:NP_001273653.1|ensembl:ENSG00000048828(gene)|ensembl:ENST00000277165(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|interpro:IPR026784|interpro:IPR029060|mint:Q9NZB2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:rUAiAHBq/d4CZZ0K56M5fkb4+dA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q99459 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-374880|uniprotkb:Q76N46|uniprotkb:Q99974|ensembl:ENSP00000360532 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cdc5l_human(display_long)|uniprotkb:CDC5L(gene name)|psi-mi:CDC5L(display_short)|uniprotkb:Pombe cdc5-related protein(gene name synonym)|uniprotkb:KIAA0432(gene name synonym)|uniprotkb:PCDC5RP(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|rcsb pdb:6ID1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071352"(cellular response to interleukin-2)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904568"(cellular response to wortmannin)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990646"(cellular response to prolactin)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR021786|mint:Q99459|rcsb pdb:2DIM|rcsb pdb:2DIN|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|ensembl:ENSG00000096401(gene)|ensembl:ENST00000371477(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:6QDV|rcsb pdb:6ZYM|rcsb pdb:7A5P|rcsb pdb:7AAV|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|refseq:NP_001244.1|dip:DIP-31731N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ZNRraJHn//46wKLSx7xtZju/lr09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62280 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1047710|uniprotkb:B2R4F5|uniprotkb:P04643|uniprotkb:Q498Y6|uniprotkb:Q6IRY0|ensembl:ENSP00000270625 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs11_human(display_long)|uniprotkb:RPS11(gene name)|psi-mi:RPS11(display_short)|uniprotkb:Small ribosomal subunit protein uS17(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001006.1|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62280|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|go:"GO:0005840"(ribosome)|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|ensembl:ENSG00000142534(gene)|ensembl:ENST00000270625(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6OM0|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:0fqJjtWAuz31VTKt2mbteRoi8vA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q99570 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1046979|uniprotkb:Q2TBF4|ensembl:ENSP00000349205 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pi3r4_human(display_long)|uniprotkb:PI3-kinase p150 subunit(gene name synonym)|uniprotkb:Phosphoinositide 3-kinase adaptor protein(gene name synonym)|uniprotkb:PIK3R4(gene name)|psi-mi:PIK3R4(display_short)|uniprotkb:VPS15(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055417.1|ensembl:ENSG00000196455(gene)|ensembl:ENST00000356763(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0030242"(autophagy of peroxisome)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR036322|mint:Q99570|rcsb pdb:7BL1|reactome:R-HSA-109704|reactome:R-HSA-1632852|reactome:R-HSA-1660514|reactome:R-HSA-1660516|reactome:R-HSA-1660517|reactome:R-HSA-168138|reactome:R-HSA-5668599|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034271"(phosphatidylinositol 3-kinase complex, class III, type I)|go:"GO:0034272"(phosphatidylinositol 3-kinase complex, class III, type II)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0071561"(nucleus-vacuole junction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001680(WD40 repeat)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-42310N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:CjToF5FvjyANBQtA1wuWQxC82889606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q15393 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P78527 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352053|uniprotkb:P78528|uniprotkb:Q13327|uniprotkb:Q13337|uniprotkb:Q14175|uniprotkb:Q59H99|uniprotkb:Q7Z611|uniprotkb:Q96SE6|uniprotkb:Q9UME3|ensembl:ENSP00000313420 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:prkdc_human(display_long)|uniprotkb:PRKDC(gene name)|psi-mi:PRKDC(display_short)|uniprotkb:HYRC(gene name synonym)|uniprotkb:HYRC1(gene name synonym)|uniprotkb:DNPK1(gene name synonym)|uniprotkb:p460(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001075109.1|refseq:NP_008835.5|ensembl:ENSG00000253729(gene)|ensembl:ENST00000314191(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001756"(somitogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002328"(pro-B cell differentiation)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002638"(negative regulation of immunoglobulin production)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004677"(DNA-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005958"(DNA-dependent protein kinase-DNA ligase 4 complex)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016233"(telomere capping)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033152"("immunoglobulin V(D)J recombination")|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0035234"(ectopic germ cell programmed cell death)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:2001229"(negative regulation of response to gamma radiation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012582(NUC194)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR037706|mint:P78527|go:"GO:0106310"(protein serine kinase activity)|rcsb pdb:5LUQ|rcsb pdb:5W1R|rcsb pdb:5Y3R|rcsb pdb:6ZFP|rcsb pdb:6ZH2|rcsb pdb:6ZH4|go:"GO:0106311"|rcsb pdb:6ZH6|rcsb pdb:6ZH8|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7K0Y|rcsb pdb:7K10|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|rcsb pdb:7K11|rcsb pdb:7K19|go:"GO:1905221"(positive regulation of platelet formation)|rcsb pdb:7K1B|rcsb pdb:7K1J|go:"GO:2000773"(negative regulation of cellular senescence)|rcsb pdb:7K1K|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|rcsb pdb:7K1N|rcsb pdb:7LT3|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-8866654|ensembl:ENSP00000313420|ensembl:ENST00000338368|ensembl:ENSP00000345182|dip:DIP-24186N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:WKXDHilQTGO8zQRd8ZcMYha99PM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P82933 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-721385|intact:EBI-1049991|uniprotkb:Q6PG40|ensembl:ENSP00000258455 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt09_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short)|uniprotkb:RPMS9(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS9m(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_872578.1|ensembl:ENSG00000135972(gene)|ensembl:ENST00000258455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P82933|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSE psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XNB4GL84eYgYFEB3WxOtoD3Ub989606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62847 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354515|uniprotkb:P16632|uniprotkb:Q7Z3D1|uniprotkb:Q5T0P7|uniprotkb:Q5T0P8|uniprotkb:E7EPK6|ensembl:ENSP00000478869 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs24_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short)|uniprotkb:Small ribosomal subunit protein eS24(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001135757.1|refseq:NP_001017.1|refseq:NP_001135755.1|refseq:NP_148982.1|ensembl:ENSG00000138326(gene)|ensembl:ENST00000613865(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|mint:P62847|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6XA1|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:M/qkRxabHx9PFaOM7EwKDOOwu7Q9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q4J6C6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-949331|uniprotkb:A7E2X6|uniprotkb:O43163|uniprotkb:Q4J6C3|uniprotkb:Q4J6C4|uniprotkb:Q4ZG39|uniprotkb:Q6ZMW7|uniprotkb:Q96DW7|uniprotkb:D6W5A3|ensembl:ENSP00000260648|ensembl:ENSP00000386509|ensembl:ENSP00000386543|ensembl:ENSP00000386909|ensembl:ENSP00000391456|ensembl:ENSP00000409480 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ppcel_human(display_long)|uniprotkb:KIAA0436(gene name synonym)|uniprotkb:Prolylendopeptidase-like(gene name synonym)|uniprotkb:PREPL(gene name)|psi-mi:PREPL(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001035844.1|refseq:NP_001035845.1|refseq:NP_001165074.1|refseq:NP_001165077.1|refseq:NP_001165084.1|refseq:NP_001165088.1|refseq:NP_006027.2|refseq:XP_011531500.1|refseq:XP_011531502.1|refseq:XP_011531504.1|refseq:XP_016860873.1|refseq:XP_016860874.1|ensembl:ENSG00000138078(gene)|ensembl:ENST00000260648(transcript)|ensembl:ENST00000409272(transcript)|ensembl:ENST00000409936(transcript)|ensembl:ENST00000410081(transcript)|ensembl:ENST00000425263(transcript)|ensembl:ENST00000426481(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008233"(peptidase activity)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR023302|interpro:IPR029058 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:xn++9zR6AX/HzP4KzrriJR5IUTk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62701 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P51911 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2873130|ensembl:ENSP00000252456|uniprotkb:B4DUX6|uniprotkb:Q8IY93|uniprotkb:Q15416|uniprotkb:O00638|uniprotkb:Q99438|uniprotkb:B2R868 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cnn1_human(display_long)|uniprotkb:CNN1(gene name)|psi-mi:CNN1(display_short)|uniprotkb:Basic calponin(gene name synonym)|uniprotkb:Calponin H1, smooth muscle(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000130176(gene)|ensembl:ENST00000252456(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|rcsb pdb:1WYP|refseq:NP_001295270.1|refseq:NP_001290.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:blXz1RLzyvJ1QIZzI3knBEC2qoA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q4VXU2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880591|ensembl:ENSP00000255136|uniprotkb:Q4VY17 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pap1l_human(display_long)|uniprotkb:PABPC1L(gene name)|psi-mi:PABPC1L(display_short)|uniprotkb:C20orf119(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000101104(gene)|ensembl:ENST00000255136(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|refseq:NP_001118228.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:gcrGSQPJzPIFPw/UbVeQ+wqYfbA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00541 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1053271|uniprotkb:Q6IC29|ensembl:ENSP00000346725 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pesc_human(display_long)|uniprotkb:PES1(gene name)|psi-mi:PES1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001230154.1|refseq:NP_055118.1|ensembl:ENSG00000100029(gene)|ensembl:ENST00000354694(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070545"(PeBoW complex)|interpro:IPR001357(BRCT)|interpro:IPR010613(Pescadillo, N-terminal)|interpro:IPR036420|rcsb pdb:2EP8|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Nq1SJ37kJfe+vF9zmNASz1gnbfY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P05388 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NPJ6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6NVV1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880684 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:r13p3_human(display_long)|uniprotkb:RPL13AP3(gene name)|psi-mi:RPL13AP3(display_short)|uniprotkb:60S ribosomal protein L13a pseudogene 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR036899 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XmYWkWYmWbCrPqmISrFtJ/k+cnI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UKN8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1237240|uniprotkb:Q5VZJ7|ensembl:ENSP00000361219 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tf3c4_human(display_long)|uniprotkb:GTF3C4(gene name)|psi-mi:GTF3C4(display_short)|uniprotkb:Transcription factor IIIC subunit delta(gene name synonym)|uniprotkb:TF3C-delta(gene name synonym)|uniprotkb:Transcription factor IIIC 90 kDa subunit(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_036336.2|ensembl:ENSG00000125484(gene)|ensembl:ENST00000372146(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR024761|interpro:IPR024764|interpro:IPR036322|interpro:IPR044230|mint:Q9UKN8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:OFldz80WMs7KQ59Of0rkkj80lyc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y3U8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P16520 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880663|uniprotkb:Q9BQC0|uniprotkb:Q96B71|ensembl:ENSP00000229264 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gbb3_human(display_long)|uniprotkb:GNB3(gene name)|psi-mi:GNB3(display_short)|uniprotkb:Transducin beta chain 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 dip:DIP-601N|refseq:NP_001284500.1|refseq:NP_002066.1|ensembl:ENSG00000111664(gene)|ensembl:ENST00000229264(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:1903725"(regulation of phospholipid metabolic process)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-381771|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:hYRSnueBN7eZ3RZtnP6WnOPTX3A9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y4F4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880628|ensembl:ENSP00000355045|uniprotkb:Q6PG27|uniprotkb:Q68D66 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tgrm1_human(display_long)|uniprotkb:TOGARAM1(gene name)|psi-mi:TOGARAM1(display_short)|uniprotkb:Crescerin-1(gene name synonym)|uniprotkb:FAM179B(gene name synonym)|uniprotkb:KIAA0423(gene name synonym)|uniprotkb:Protein FAM179B(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000198718(gene)|ensembl:ENST00000361577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0008017"(microtubule binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0035082"(axoneme assembly)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028401|interpro:IPR034085|refseq:XP_016876589.1|refseq:NP_055906.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:gI7Lh/rfVuQOm6+iw2//pSwaGuE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q7KZF4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q08043 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880652|ensembl:ENSP00000426797|uniprotkb:Q4KKV2|uniprotkb:A6NP77 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:actn3_human(display_long)|uniprotkb:ACTN3(gene name)|psi-mi:ACTN3(display_short)|uniprotkb:Alpha-actinin skeletal muscle isoform 3(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0051015"(actin filament binding)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1901078"(negative regulation of relaxation of muscle)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904025"(positive regulation of glucose catabolic process to lactate via pyruvate)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|ensembl:ENSG00000248746(gene)|ensembl:ENST00000513398(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014728"(regulation of the force of skeletal muscle contraction)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0030018"(Z disc)|go:"GO:0031143"(pseudopodium)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0042802"(identical protein binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|rcsb pdb:1TJT|rcsb pdb:1WKU|rcsb pdb:3LUE|reactome:R-HSA-373753|reactome:R-HSA-390522|refseq:NP_001245300.2|refseq:NP_001095.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ihTlyeKGYaTOZTmd5oP5FeFmo089606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H0A0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-876527|ensembl:ENSP00000257829|uniprotkb:B4DFD5|uniprotkb:E7ESU4|uniprotkb:E9PMN9|uniprotkb:Q86WK5|uniprotkb:Q9C0F4|uniprotkb:Q9HA61|uniprotkb:Q9NVF2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nat10_human(display_long)|uniprotkb:NAT10(gene name)|psi-mi:NAT10(display_short)|uniprotkb:KIAA1709(gene name synonym)|uniprotkb:ALP(gene name synonym)|uniprotkb:18S rRNA cytosine acetyltransferase(gene name synonym)|uniprotkb:N-acetyltransferase 10(gene name synonym)|uniprotkb:N-acetyltransferase-like protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000135372(gene)|ensembl:ENST00000257829(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000154"(rRNA modification)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006473"(protein acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051391"(tRNA acetylation)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0106162"(mRNA N-acetyltransferase activity)|go:"GO:1904812"(rRNA acetylation involved in maturation of SSU-rRNA)|go:"GO:1990883"(rRNA cytidine N-acetyltransferase activity)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR007807(Protein of unknown function DUF699, ATPase putative)|interpro:IPR013562(Region of unknown function DUF1726)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR027992|interpro:IPR032672|interpro:IPR033688|mint:Q9H0A0|rcsb pdb:6VLA|reactome:R-HSA-6790901|refseq:NP_001137502.1|refseq:NP_078938.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3eWpscghkRC8Km7mBsUQqjhCKVs9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62750 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9P2R3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2513908|uniprotkb:Q5RKV4|uniprotkb:Q9ULG5|uniprotkb:A8KA65|intact:EBI-2838972|intact:EBI-2948552|ensembl:ENSP00000343362|ensembl:ENSP00000497187 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:anfy1_human(display_long)|uniprotkb:Ankyrin repeat and FYVE domain-containing protein 1(gene name synonym)|uniprotkb:ANKFY1(gene name)|psi-mi:ANKFY1(display_short)|uniprotkb:ANKHZN(gene name synonym)|uniprotkb:KIAA1255(gene name synonym)|uniprotkb:Ankyrin repeats hooked to a zinc finger motif(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_057460.3|refseq:NP_001316992.1|refseq:NP_001244928.1|dip:DIP-46068N|ensembl:ENSG00000185722(gene)|ensembl:ENST00000341657(transcript)|ensembl:ENST00000648043(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044354"(macropinosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002110(Ankyrin)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-9013405 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:237ungtRc80jqTOKBUnFX9qDUGw9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P53814 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1199956|intact:EBI-1199983|uniprotkb:Q8N4H8|uniprotkb:Q8WWW1|uniprotkb:Q8WWW2|uniprotkb:O00569|uniprotkb:O95769|uniprotkb:O95937|uniprotkb:Q9P1S8|uniprotkb:Q9UIT1|uniprotkb:Q9UIT2|ensembl:ENSP00000328635 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:smtn_human(display_long)|uniprotkb:SMTN(gene name)|psi-mi:SMTN(display_short)|uniprotkb:SMSMO(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000183963(gene)|ensembl:ENST00000347557(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:P53814|rcsb pdb:2D87|refseq:NP_001193946.1|refseq:NP_001193947.1|refseq:NP_008863.3|refseq:NP_599031.1|refseq:NP_599032.2|ensembl:ENST00000333137|ensembl:ENSP00000329532|ensembl:ENSP00000328635|ensembl:ENST00000358743|ensembl:ENSP00000351593 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:na+f9ZixP42TZZ0uD5P5tzaroFA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y520 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2685847|uniprotkb:Q05DM8|uniprotkb:Q9HA05|uniprotkb:Q9UF29|uniprotkb:Q9NSM8|uniprotkb:Q9H2N2|uniprotkb:Q9NXL3|uniprotkb:Q6PD54|uniprotkb:Q49A39|uniprotkb:Q9UPQ6|intact:EBI-2824421 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:prc2c_human(display_long)|uniprotkb:BAT2D1(gene name synonym)|uniprotkb:KIAA1096(gene name synonym)|uniprotkb:XTP2(gene name synonym)|uniprotkb:BAT2 domain-containing protein 1(gene name synonym)|uniprotkb:HBV X-transactivated gene 2 protein(gene name synonym)|uniprotkb:HBV XAg-transactivated protein 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 2-like 2(gene name synonym)|uniprotkb:PRRC2C(gene name)|psi-mi:PRRC2C(display_short)|uniprotkb:BAT2L2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2C(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055987.2|refseq:XP_006711301.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034063"(stress granule assembly)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|ensembl:ENST00000338920|ensembl:ENSP00000343629|ensembl:ENSG00000117523|ensembl:ENST00000426496|ensembl:ENSP00000410219|ensembl:ENST00000647382|ensembl:ENSP00000495867|refseq:XP_005245074.1|dip:DIP-47285N|mint:Q9Y520 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:qecMuJHnm8n95OFpT+m+i9JbBoo9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UBD9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880701|ensembl:ENSP00000309338|uniprotkb:Q6NZA4|uniprotkb:B4DNT4 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:clcf1_human(display_long)|uniprotkb:CLCF1(gene name)|psi-mi:CLCF1(display_short)|uniprotkb:BSF3(gene name synonym)|uniprotkb:CLC(gene name synonym)|uniprotkb:NNT1(gene name synonym)|uniprotkb:B-cell-stimulating factor 3(gene name synonym)|uniprotkb:Novel neurotrophin-1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000175505(gene)|ensembl:ENST00000312438(transcript)|go:"GO:0097059"(CNTFR-CLCF1 complex)|interpro:IPR009079(Four-helical cytokine-like, core)|interpro:IPR010681(Plethodontid receptivity factor PRF)|reactome:R-HSA-6788467|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008083"(growth factor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0048295"(positive regulation of isotype switching to IgE isotypes)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0097058"(CRLF-CLCF1 complex)|go:"GO:0002639"(positive regulation of immunoglobulin production)|refseq:NP_001159684.1|refseq:NP_037378.1|dip:DIP-61204N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3mNN0yrnBn2Bpal6AyU3KUb2xFI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8IZL8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H1R3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-356910|uniprotkb:Q569L1|uniprotkb:Q96I84|ensembl:ENSP00000365152|ensembl:ENSP00000365162 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:mylk2_human(display_long)|uniprotkb:MYLK2(gene name)|psi-mi:MYLK2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_149109.1|ensembl:ENSP00000365152|ensembl:ENSP00000365162|ensembl:ENSG00000101306(gene)|ensembl:ENST00000375985(transcript)|ensembl:ENST00000375994(transcript)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004687"(myosin light chain kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014816"(skeletal muscle satellite cell differentiation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030017"(sarcomere)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032971"(regulation of muscle filament sliding)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR042717|rcsb pdb:2LV6|rcsb pdb:3KF9 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:VfJn/QlOkBjTcPHsi+5EkEQY3/c9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P48552 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UJV9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1046350|ensembl:ENSP00000330349|uniprotkb:Q96BK6|uniprotkb:Q96K05|uniprotkb:Q9NT96|uniprotkb:Q9NW04|uniprotkb:B2RDC8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ddx41_human(display_long)|uniprotkb:DEAD box protein 41(gene name synonym)|uniprotkb:DEAD box protein abstrakt homolog(gene name synonym)|uniprotkb:DDX41(gene name)|psi-mi:DDX41(display_short)|uniprotkb:ABS(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000183258(gene)|ensembl:ENST00000330503(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044113|mint:Q9UJV9|rcsb pdb:2P6N|rcsb pdb:5GVS|rcsb pdb:5H1Y|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-3270619|rcsb pdb:5GVR|refseq:NP_057306.2|refseq:NP_001308661.1|refseq:NP_001308759.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:a3HNDsQBaXs/1q8ZXjkcMgEhPes9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P20930 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1058782|ensembl:ENSP00000357789|uniprotkb:Q01720|uniprotkb:Q5T583|uniprotkb:Q9UC71 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:fila_human(display_long)|uniprotkb:FLG(gene name)|psi-mi:FLG(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000368799(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0007275"(multicellular organism development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0036457"(keratohyalin granule)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0061436"(establishment of skin barrier)|ensembl:ENSG00000143631(gene)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003303(Filaggrin)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR034325|rcsb pdb:4PCW|reactome:R-HSA-6809371|go:"GO:0062023"(collagen-containing extracellular matrix)|refseq:NP_002007.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:RXgRbd4W6ydxD/M1cEUUzUFGuJ09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NXF1 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2371062|uniprotkb:Q5T722|uniprotkb:Q5T723|uniprotkb:Q8NCN8|uniprotkb:Q8TDY0|uniprotkb:B4DYV2|ensembl:ENSP00000364037 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tex10_human(display_long)|uniprotkb:TEX10(gene name)|psi-mi:TEX10(display_short)|uniprotkb:L18(orf name)|uniprotkb:Nbla10363(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060216.2|refseq:NP_001155056.1|ensembl:ENSG00000136891(gene)|ensembl:ENST00000374902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|mint:Q9NXF1|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:cQcRo1eExRkr/an7wvBN8Ttyatc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UF83 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880647|uniprotkb:Q9UFS5|uniprotkb:Q9NTQ6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ym012_human(display_long) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0005615"(extracellular space) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:wRFMPl991k1c4SRkbMZAcZkPIek9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O75420 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-947774|uniprotkb:Q6Y7W7|uniprotkb:Q8WZ38|intact:EBI-28969313|ensembl:ENSP00000275732|ensembl:ENSP00000494292|ensembl:ENSP00000503354 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ggyf1_human(display_long)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 1(gene name synonym)|uniprotkb:GIGYF1(gene name)|psi-mi:GIGYF1(display_short)|uniprotkb:CDS2(gene name synonym)|uniprotkb:PERQ1(gene name synonym)|uniprotkb:PP3360(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSP00000275732|ensembl:ENSP00000494292|ensembl:ENSP00000503354|refseq:NP_072096.2|refseq:XP_005250589.1|ensembl:ENSG00000146830(gene)|ensembl:ENST00000275732(transcript)|ensembl:ENST00000646601(transcript)|ensembl:ENST00000678049(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVK psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:9JsxoywLfULBy9NYDNlxmfB1Xkw9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96TC7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1056589|uniprotkb:A9UMZ9|uniprotkb:Q6ZWE9|uniprotkb:Q96H23|uniprotkb:Q96SD6|uniprotkb:Q9H6G1|uniprotkb:Q9NVQ6|uniprotkb:B3KRR3|intact:EBI-2563869|ensembl:ENSP00000260385|ensembl:ENSP00000342493 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rmd3_human(display_long)|uniprotkb:Protein tyrosine phosphatase-interacting protein 51(gene name synonym)|uniprotkb:TCPTP-interacting protein 51(gene name synonym)|uniprotkb:UNQ3122/PRO10274(orf name)|uniprotkb:hucep-10(orf name)|uniprotkb:RMDN3(gene name)|psi-mi:RMDN3(display_short)|uniprotkb:Cerebral protein 10(gene name synonym)|uniprotkb:FAM82A2(gene name synonym)|uniprotkb:FAM82C(gene name synonym)|uniprotkb:PTPIP51(gene name synonym)|uniprotkb:Protein FAM82A2(gene name synonym)|uniprotkb:Protein FAM82C(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060615.1|refseq:NP_001310823.1|refseq:NP_001310824.1|refseq:NP_001291731.1|ensembl:ENSG00000137824(gene)|ensembl:ENST00000260385(transcript)|ensembl:ENST00000338376(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045171"(intercellular bridge)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:7CC7 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:+y9NPJiIL0BOpjWINH8zcfp5b9o9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q01130 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-627047|uniprotkb:B3KWD5|ensembl:ENSP00000353089|ensembl:ENSP00000376276|ensembl:ENSP00000391278|ensembl:ENSP00000462425|uniprotkb:B4DN89|uniprotkb:H0YG49 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:srsf2_human(display_long)|uniprotkb:Splicing factor SC35(gene name synonym)|uniprotkb:Splicing component, 35 kDa(gene name synonym)|uniprotkb:Protein PR264(gene name synonym)|uniprotkb:SRSF2(gene name)|psi-mi:SRSF2(display_short)|uniprotkb:SFRS2(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000161547(gene)|ensembl:ENST00000359995(transcript)|ensembl:ENST00000392485(transcript)|ensembl:ENST00000452355(transcript)|ensembl:ENST00000585202(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035061"(interchromatin granule)|go:"GO:0036002"(pre-mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034893|interpro:IPR035979|mint:Q01130|rcsb pdb:2KN4|rcsb pdb:2LEA|rcsb pdb:2LEB|rcsb pdb:2LEC|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0003723"(RNA binding)|refseq:NP_001182356.1|refseq:NP_003007.2|refseq:XP_016880431.1|dip:DIP-33836N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:/LUrJ8xa42APUsgH5ke590Kxsh89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q05639 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P35606 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1056534|uniprotkb:B4DZI8|intact:EBI-11019844|ensembl:ENSP00000329419 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:copb2_human(display_long)|uniprotkb:COPB2(gene name)|psi-mi:COPB2(display_short)|uniprotkb:Beta'-coat protein(gene name synonym)|uniprotkb:p102(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004757.1|ensembl:ENSG00000184432(gene)|ensembl:ENST00000333188(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:1901998"(toxin transport)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016453(Coatomer, beta' subunit)|interpro:IPR020472|interpro:IPR036322|mint:P35606|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:XP_016863001.1|dip:DIP-27603N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:zkd7lOeV+OvHglnAJg6cXoMhgbg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P82914 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O75448 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8TAQ2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q5JTH9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-310743|uniprotkb:Q5JTH8|uniprotkb:Q69YK4|uniprotkb:Q96E87|uniprotkb:Q9BUH3|uniprotkb:Q9Y4C7|intact:EBI-2558452|uniprotkb:B4DK00|uniprotkb:E9PCK7|intact:EBI-28986119|ensembl:ENSP00000360031|ensembl:ENSP00000446184 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rrp12_human(display_long)|uniprotkb:RRP12(gene name)|psi-mi:RRP12(display_short)|uniprotkb:KIAA0690(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001138586.1|refseq:NP_055994.2|refseq:NP_001271266.1|ensembl:ENST00000315563|ensembl:ENSP00000324315|ensembl:ENSP00000360031|ensembl:ENST00000414986|ensembl:ENSP00000414863|ensembl:ENSP00000446184|ensembl:ENSG00000052749(gene)|ensembl:ENST00000370992(transcript)|ensembl:ENST00000536831(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012978(Region of unknown function, NUC173)|interpro:IPR016024(Armadillo-type fold)|mint:Q5JTH9 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:O2Ih3mwXBDMynmqc4UzvizKVnNg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62269 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352451|ensembl:ENSP00000211372|ensembl:ENSP00000393241|ensembl:ENSP00000403175|ensembl:ENSP00000412583|ensembl:ENSP00000416110|uniprotkb:P25232|uniprotkb:Q6IPF8|uniprotkb:Q5SUJ3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs18_human(display_long)|uniprotkb:RPS18(gene name)|psi-mi:RPS18(display_short)|uniprotkb:D6S218E(gene name synonym)|uniprotkb:Ke-3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS13(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_072045.1|ensembl:ENSG00000096150(gene)|ensembl:ENSG00000223367(gene)|ensembl:ENSG00000226225(gene)|ensembl:ENSG00000231500(gene)|ensembl:ENSG00000235650(gene)|ensembl:ENST00000211372(transcript)|ensembl:ENST00000434122(transcript)|ensembl:ENST00000439602(transcript)|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENST00000454021(transcript)|ensembl:ENST00000457341(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62269|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|dip:DIP-32892N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:yOHgKM/BuvgGdqp1OEVPeuiABg89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P18124 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O60264 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352588|ensembl:ENSP00000283131 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:smca5_human(display_long)|uniprotkb:SMARCA5(gene name)|psi-mi:SMARCA5(display_short)|uniprotkb:SNF2H(gene name synonym)|uniprotkb:WCRF135(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2 homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000283131(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031213"(RSF complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|mint:O60264|rcsb pdb:6NE3|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5693565|reactome:R-HSA-606279|refseq:NP_003592.3|ensembl:ENSG00000153147(gene)|dip:DIP-33204N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XlXL5MRhAFlqHhGroPdm01lYEk89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P49756 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62249 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-352480|uniprotkb:P17008|uniprotkb:B2RDD5|ensembl:ENSP00000251453 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs16_human(display_long)|uniprotkb:RPS16(gene name)|psi-mi:RPS16(display_short)|uniprotkb:Small ribosomal subunit protein uS9(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001011.1|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000105193(gene)|ensembl:ENST00000251453(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62249|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|dip:DIP-33200N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:OrKriR6HsATLaO+drdUa2w3Gpd09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BRJ2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2514313|ensembl:ENSP00000483030|uniprotkb:Q6ZMJ5|uniprotkb:A1L436 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rm45_human(display_long)|uniprotkb:MRPL45(gene name)|psi-mi:MRPL45(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL45(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000277936(gene)|ensembl:ENST00000621878(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR032710|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|dip:DIP-53786N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:9NtO1r7W7U9BW3vB9RTRbwehBZ49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q14315 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-489954|uniprotkb:O95303|uniprotkb:Q07985|uniprotkb:Q9NS12|uniprotkb:Q9NYE5|uniprotkb:Q9UMR8|uniprotkb:Q9Y503|uniprotkb:B2ZZ88|ensembl:ENSP00000327145 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:flnc_human(display_long)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:FLNC(gene name)|psi-mi:FLNC(display_short)|uniprotkb:ABPL(gene name synonym)|uniprotkb:FLN2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001120959.1|refseq:NP_001449.3|ensembl:ENSG00000128591(gene)|ensembl:ENST00000325888(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q14315|rcsb pdb:1V05|rcsb pdb:2D7M|rcsb pdb:2D7N|rcsb pdb:2D7O|rcsb pdb:2D7P|rcsb pdb:2D7Q|rcsb pdb:2K9U|rcsb pdb:2NQC|rcsb pdb:3V8O|rcsb pdb:4MGX|reactome:R-HSA-446353|dip:DIP-33398N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:sBGhjObBECicoAu/8T5lDIt1ToY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y2X0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q13428 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-396105|uniprotkb:Q6SC72|uniprotkb:Q7Z5W9|uniprotkb:Q96A52|uniprotkb:Q99408|uniprotkb:Q99860|uniprotkb:A0JLU0|uniprotkb:B4E111|intact:EBI-28974716|ensembl:ENSP00000367028|ensembl:ENSP00000421655 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tcof_human(display_long)|uniprotkb:TCOF1(gene name)|psi-mi:TCOF1(display_short)|uniprotkb:Treacher Collins syndrome protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000347.2|refseq:NP_001008657.1|refseq:NP_001128715.1|refseq:NP_001128716.1|refseq:NP_001128717.1|refseq:NP_001182070.1|ensembl:ENST00000323668|ensembl:ENSP00000325223|ensembl:ENSP00000367028|ensembl:ENST00000394269|ensembl:ENSP00000377811|ensembl:ENST00000427724|ensembl:ENSP00000390717|ensembl:ENST00000439160|ensembl:ENSP00000406888|ensembl:ENST00000445265|ensembl:ENSP00000409944|ensembl:ENSP00000421655|ensembl:ENST00000643257|ensembl:ENSP00000493815|refseq:XP_005268562.1|ensembl:ENSG00000070814(gene)|ensembl:ENST00000377797(transcript)|ensembl:ENST00000504761(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR003993(Treacher Collins syndrome, treacle)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR017859|mint:Q13428|dip:DIP-32953N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:eRazgHpn5CwQVFH5hRnA/sVp24M9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00571 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353779|uniprotkb:O15536|uniprotkb:A8K538|uniprotkb:B4E3E8|ensembl:ENSP00000478443|ensembl:ENSP00000486516|ensembl:ENSP00000486720|ensembl:ENSP00000487224|ensembl:ENSP00000494040 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ddx3x_human(display_long)|uniprotkb:DDX3X(gene name)|psi-mi:DDX3X(display_short)|uniprotkb:DBX(gene name synonym)|uniprotkb:DDX3(gene name synonym)|uniprotkb:DEAD box protein 3, X-chromosomal(gene name synonym)|uniprotkb:Helicase-like protein 2(gene name synonym)|uniprotkb:DEAD box, X isoform(gene name synonym)|uniprotkb:CAP-Rf(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001347.3|refseq:NP_001180345.1|refseq:NP_001180346.1|ensembl:ENSG00000215301(gene)|ensembl:ENST00000478993(transcript)|ensembl:ENST00000629496(transcript)|ensembl:ENST00000629785(transcript)|ensembl:ENST00000630255(transcript)|ensembl:ENST00000644876(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006413"(translational initiation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007276"(gamete generation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009615"(response to virus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034157"(positive regulation of toll-like receptor 7 signaling pathway)|go:"GO:0034161"(positive regulation of toll-like receptor 8 signaling pathway)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043186"(P granule)|go:"GO:0043273"(CTPase activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071470"(cellular response to osmotic stress)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072559"(NLRP3 inflammasome complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902523"(positive regulation of protein K63-linked ubiquitination)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00571|rcsb pdb:2I4I|rcsb pdb:2JGN|rcsb pdb:3JRV|rcsb pdb:4O2C|rcsb pdb:4O2E|rcsb pdb:4O2F|rcsb pdb:4PX9|rcsb pdb:4PXA|rcsb pdb:5E7I|rcsb pdb:5E7J|rcsb pdb:5E7M|rcsb pdb:6CZ5|rcsb pdb:6O5F|reactome:R-HSA-6798695|dip:DIP-27551N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XCZgGbfPyxLnvabmWRNNgG3HHIs9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62851 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353054|ensembl:ENSP00000435096|ensembl:ENSP00000486392|uniprotkb:P25111|uniprotkb:B2R4M7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs25_human(display_long)|uniprotkb:RPS25(gene name)|psi-mi:RPS25(display_short)|uniprotkb:Small ribosomal subunit protein eS25(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000118181(gene)|ensembl:ENSG00000280831(gene)|ensembl:ENST00000527673(transcript)|ensembl:ENST00000628770(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004977(Ribosomal protein S25)|interpro:IPR036388|mint:P62851|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y0G|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|rcsb pdb:6ZXD|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|rcsb pdb:6ZXE|reactome:R-HSA-9010553|reactome:R-HSA-9633012|rcsb pdb:6ZXF|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|refseq:NP_001019.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y5Z7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-592728|uniprotkb:B2R8Q5|uniprotkb:C0H5X3|ensembl:ENSP00000229330 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_037452.1|ensembl:ENSG00000111727(gene)|ensembl:ENST00000229330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016032"(viral process)|go:"GO:0016604"(nuclear body)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037932|interpro:IPR043536|mint:Q9Y5Z7 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UBF2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y5Q8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1045409|uniprotkb:Q8N2U7|uniprotkb:Q8N857|uniprotkb:Q96GD9|uniprotkb:Q9H4P2|uniprotkb:A6NI44|uniprotkb:A6NJB9|uniprotkb:Q5T7U2|uniprotkb:Q5T7U3|intact:EBI-2556713|ensembl:ENSP00000361169 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tf3c5_human(display_long)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:GTF3C5(gene name)|psi-mi:GTF3C5(display_short)|uniprotkb:CDABP0017(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001116295.1|refseq:NP_036219.2|ensembl:ENSG00000148308(gene)|ensembl:ENST00000372097(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q9Y5Q8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001273638.1|dip:DIP-50823N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Cb1wPs3qn4+Up/g7WgOMDEFtp+M9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UKM9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-714796|uniprotkb:Q14621|uniprotkb:Q2M365|uniprotkb:Q5QPL8|uniprotkb:Q9BQX6|uniprotkb:Q9UJE3|ensembl:ENSP00000246194 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:raly_human(display_long)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:P542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011526996.1|refseq:XP_011526997.1|ensembl:ENSG00000125970(gene)|ensembl:ENST00000246194(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034502|interpro:IPR035979|mint:Q9UKM9|rcsb pdb:1WF1|refseq:NP_031393.2|refseq:NP_057951.1|refseq:XP_005260391.1|refseq:XP_005260393.1|refseq:XP_016883220.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3hd0n2UW0FSRNvSJa2mqflVeorc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q07666 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|ensembl:ENSG00000121774(gene)|ensembl:ENST00000327300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|reactome:R-HSA-8849468 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P35222 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62829 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BQ39 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-395850|intact:EBI-2826089|uniprotkb:Q8WV76|uniprotkb:Q9BWI8|uniprotkb:Q5VX37|ensembl:ENSP00000362687 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ddx50_human(display_long)|uniprotkb:DEAD box protein 50(gene name synonym)|uniprotkb:Nucleolar protein Gu2(gene name synonym)|uniprotkb:Gu-beta(gene name synonym)|uniprotkb:DDX50(gene name)|psi-mi:DDX50(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_076950.1|ensembl:ENSG00000107625(gene)|ensembl:ENST00000373585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012562(GUCT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR035979|mint:Q9BQ39|rcsb pdb:2E29|refseq:XP_016872115.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:a8/VHQw5HVQh6L/rbsKonz0R34c9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P16403 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P41219 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-752074|uniprotkb:Q8N577|ensembl:ENSP00000257860 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:peri_human(display_long)|uniprotkb:PRPH(gene name)|psi-mi:PRPH(display_short)|uniprotkb:NEF4(gene name synonym)|uniprotkb:PRPH1(gene name synonym)|uniprotkb:Neurofilament 4(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006253.2|refseq:XP_005269082.1|ensembl:ENSG00000135406(gene)|ensembl:ENST00000257860(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0043204"(perikaryon)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027700|interpro:IPR039008|interpro:IPR006821(Intermediate filament, DNA-binding region) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:VDbDQH7o/la+KZBL4xkOLu4/cd89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P15170 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q16637 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O15164 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62424 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P08670 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P63244 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P82921 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2372155|uniprotkb:Q9BST6|uniprotkb:A0A075B746|uniprotkb:Q5TB11|ensembl:ENSP00000461930|ensembl:ENSP00000480129 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt21_human(display_long)|uniprotkb:MRPS21(gene name)|psi-mi:MRPS21(display_short)|uniprotkb:RPMS21(gene name synonym)|uniprotkb:MDS016(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein bS21m(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_061870.1|refseq:NP_114107.1|ensembl:ENSG00000266472(gene)|ensembl:ENST00000581066(transcript)|ensembl:ENST00000614145(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001911(Ribosomal protein S21)|interpro:IPR038380|mint:P82921|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:AGyHmum6PLo+BxY+wgQvG2894A49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O75122 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-913524|ensembl:ENSP00000417518|uniprotkb:Q7L8F6|uniprotkb:Q8N6R6|uniprotkb:Q9BQT3|uniprotkb:Q9BQT4|uniprotkb:Q9H7A3|uniprotkb:Q9NSZ2|intact:EBI-2514712|uniprotkb:B2RTR1|uniprotkb:F5H604|intact:EBI-10967478 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:clap2_human(display_long)|uniprotkb:CLASP2(gene name)|psi-mi:CLASP2(display_short)|uniprotkb:KIAA0627(gene name synonym)|uniprotkb:Cytoplasmic linker-associated protein 2(gene name synonym)|uniprotkb:Protein Orbit homolog 2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000163539(gene)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|ensembl:ENST00000480013(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0016020"(membrane)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1903754"(cortical microtubule plus-end)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024395|interpro:IPR034085|mint:O75122|rcsb pdb:3WOY|rcsb pdb:5NR4|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-428890|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001193973.1|refseq:NP_055912.2|dip:DIP-36804N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:FNIEvRFPqFi6NPFLsVHlKvfkN9w9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6PKG0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q09161 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q15648 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BV38 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P23396 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8NC51 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q71UM5 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H147 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2795449|uniprotkb:B2RA18|uniprotkb:Q96DE3|uniprotkb:Q9BQP2|uniprotkb:Q9H148|ensembl:ENSP00000361705 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:tdif1_human(display_long)|uniprotkb:DNTTIP1(gene name)|psi-mi:DNTTIP1(display_short)|uniprotkb:C20orf167(gene name synonym)|uniprotkb:TDIF1(gene name synonym)|uniprotkb:Terminal deoxynucleotidyltransferase-interacting factor 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_443183.1|ensembl:ENSG00000101457(gene)|ensembl:ENST00000372622(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR026064|interpro:IPR041384|mint:Q9H147|rcsb pdb:2MWI|rcsb pdb:4D6K|rcsb pdb:6Z2J|rcsb pdb:6Z2K|go:"GO:0003677"(DNA binding) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:KoYRvfphwSt5VO2ufdh6/sScYI89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00567 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-396034|uniprotkb:Q2M3T6|uniprotkb:Q9NQ05|ensembl:ENSP00000370589 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nop56_human(display_long)|uniprotkb:NOP56(gene name)|psi-mi:NOP56(display_short)|uniprotkb:NOL5A(gene name synonym)|uniprotkb:Nucleolar protein 5A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006383.2|ensembl:ENSG00000101361(gene)|ensembl:ENST00000329276(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|interpro:IPR012974(NOP5, N-terminal)|interpro:IPR012976(NOSIC)|interpro:IPR036070|interpro:IPR042239|mint:O00567|reactome:R-HSA-390471|reactome:R-HSA-6790901|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:nXIsxj5Spl+kflK0yGJFykVylmA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q13162 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 intact:EBI-25401924 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 - psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs4x_rs4y1_rs4y2_human(display_short)|psi-mi:EBI-25401924(display_long) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 - psi-mi:"MI:0469"(intact) - comment:P22090,P62701,Q8TD47 figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 - intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O60244 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9HCM4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1047162|uniprotkb:Q8IZ12|uniprotkb:Q9H975|uniprotkb:Q7Z5S1|ensembl:ENSP00000263713 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:e41l5_human(display_long)|uniprotkb:KIAA1548(gene name synonym)|uniprotkb:EPB41L5(gene name)|psi-mi:EPB41L5(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001171866.1|refseq:NP_001171867.1|refseq:NP_001171868.1|refseq:NP_065960.2|refseq:NP_001317239.1|ensembl:ENSG00000115109(gene)|ensembl:ENST00000263713(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001839"(neural plate morphogenesis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003383"(apical constriction)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006931"(substrate-dependent cell migration, cell attachment to substrate)|go:"GO:0007398"(ectoderm development)|go:"GO:0007492"(endoderm development)|go:"GO:0007509"(mesoderm migration involved in gastrulation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009826"(unidimensional cell growth)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032525"(somite rostral/caudal axis specification)|go:"GO:0032587"(ruffle membrane)|go:"GO:0048319"(axial mesoderm morphogenesis)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030694|interpro:IPR035963|reactome:R-HSA-6794361 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:CJuB1zHpmsK3te4K5lBNrL5tyxc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9P2F8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2797173|uniprotkb:Q5VXR8|uniprotkb:Q641Q4|uniprotkb:Q5VXR7|uniprotkb:Q9H9F6|uniprotkb:Q96DZ3|uniprotkb:Q8NA38|intact:EBI-2880635|uniprotkb:Q2TV88|ensembl:ENSP00000262861|ensembl:ENSP00000355589|ensembl:ENSP00000502693 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:si1l2_human(display_long)|uniprotkb:KIAA1389(gene name synonym)|uniprotkb:SIPA1L2(gene name)|psi-mi:SIPA1L2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011542545.1|refseq:NP_065859.3|refseq:XP_005273268.1|refseq:XP_005273269.1|refseq:XP_005273270.1|ensembl:ENSG00000116991(gene)|ensembl:ENST00000262861(transcript)|ensembl:ENST00000366630(transcript)|ensembl:ENST00000674635(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR031203|interpro:IPR035974|interpro:IPR036034|refseq:XP_016857385.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:qmmHDrxjsNJ1RR8ixhGC0ohDCFM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96Q27 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880677|uniprotkb:Q9Y567|uniprotkb:B2RDP9|uniprotkb:Q9NSU5|uniprotkb:B4E166|ensembl:ENSP00000451575|ensembl:ENSP00000480388 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:asb2_human(display_long)|uniprotkb:ASB2(gene name)|psi-mi:ASB2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_057234.2|refseq:NP_001189358.1|refseq:XP_005267815.1|ensembl:ENSG00000100628(gene)|ensembl:ENSG00000278693(gene)|ensembl:ENST00000555019(transcript)|ensembl:ENST00000612647(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001947"(heart looping)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0014732"(skeletal muscle atrophy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030018"(Z disc)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0071800"(podosome assembly)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036036|interpro:IPR036770|interpro:IPR037330|reactome:R-HSA-8951664|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ro7HeeKhV1dq5Lmm6WPU0eUrGK89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92665 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O95782 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353552|uniprotkb:Q96CI7|uniprotkb:Q96PP6|uniprotkb:Q96PP7|uniprotkb:Q9H070|intact:EBI-28973302|ensembl:ENSP00000351926 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ap2a1_human(display_long)|uniprotkb:AP2A1(gene name)|psi-mi:AP2A1(display_short)|uniprotkb:ADTAA(gene name synonym)|uniprotkb:CLAPA1(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_055018.2|refseq:NP_570603.2|ensembl:ENST00000354293|ensembl:ENSP00000346246|ensembl:ENSP00000351926|ensembl:ENSG00000196961(gene)|ensembl:ENST00000359032(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0032433"(filopodium tip)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:O95782|reactome:R-HSA-167590|reactome:R-HSA-177504|reactome:R-HSA-182218|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-416993|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9679191|dip:DIP-33164N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:egkaIAhvIi1FqNr+8KEFeJaYZcc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q14683 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8WXR4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-350672|uniprotkb:Q8IX64|uniprotkb:Q8IX65|uniprotkb:Q8IX66|uniprotkb:Q8IX67|uniprotkb:Q8IX68|uniprotkb:Q53QE1|uniprotkb:Q53T08|uniprotkb:Q96N94|ensembl:ENSP00000386213|uniprotkb:B8ZZR2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myo3b_human(display_long)|uniprotkb:MYO3B(gene name)|psi-mi:MYO3B(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0106311"|refseq:NP_001077084.2|refseq:NP_620482.3|ensembl:ENSG00000071909(gene)|ensembl:ENST00000408978(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016459"(myosin complex)|go:"GO:0032426"(stereocilium tip)|go:"GO:0050896"(response to stimulus)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027417|interpro:IPR036083|interpro:IPR036961|reactome:R-HSA-9662360|reactome:R-HSA-9662361|interpro:IPR000048(IQ calmodulin-binding region)|refseq:XP_006712362.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Z+PJYaHeID7gWPwlwjLr3pBvnYM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q86WZ0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880714|uniprotkb:B7Z7V9|uniprotkb:E9KL41|ensembl:ENSP00000335447|ensembl:ENSP00000450444 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:heat4_human(display_long)|uniprotkb:HEATR4(gene name)|psi-mi:HEATR4(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000187105(gene)|ensembl:ENST00000334988(transcript)|ensembl:ENST00000553558(transcript)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:XP_011535062.1|refseq:NP_001207413.1|refseq:NP_976054.2|refseq:XP_006720206.1|refseq:XP_016876778.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uKHbCGhhTEApENLBxV6rPWH4rrs9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BZE4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:wTcBrIj6c27um4RnJH81grRgutc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P35498 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880618|ensembl:ENSP00000303540|ensembl:ENSP00000501589|uniprotkb:Q16172|uniprotkb:Q9C008|uniprotkb:Q96LA3|uniprotkb:Q585T7|uniprotkb:E9PG49|uniprotkb:Q8IUJ6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:scn1a_human(display_long)|uniprotkb:SCN1A(gene name)|psi-mi:SCN1A(display_short)|uniprotkb:NAC1(gene name synonym)|uniprotkb:SCN1(gene name synonym)|uniprotkb:Sodium channel protein brain I subunit alpha(gene name synonym)|uniprotkb:Sodium channel protein type I subunit alpha(gene name synonym)|uniprotkb:Voltage-gated sodium channel subunit alpha Nav1.1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086010"(membrane depolarization during action potential)|interpro:IPR001696(Na+ channel)|interpro:IPR005821(Ion transport)|interpro:IPR008051(Na+ channel 1)|interpro:IPR010526(Sodium ion transport-associated)|interpro:IPR024583|interpro:IPR027359|go:"GO:0030018"(Z disc)|interpro:IPR043203|interpro:IPR044564|mint:P35498|rcsb pdb:7DTD|reactome:R-HSA-445095|reactome:R-HSA-5576892|go:"GO:0030424"(axon)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0035725"(sodium ion transmembrane transport)|ensembl:ENSG00000144285(gene)|ensembl:ENST00000303395(transcript)|ensembl:ENST00000674923(transcript)|go:"GO:0001518"(voltage-gated sodium channel complex)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005248"(voltage-gated sodium channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0016604"(nuclear body)|go:"GO:0019228"(neuronal action potential)|refseq:XP_011509904.1|refseq:XP_011509906.1|refseq:XP_011509908.1|refseq:XP_016860133.1|refseq:XP_016860134.1|refseq:XP_016860135.1|refseq:XP_016860136.1|refseq:XP_016860137.1|refseq:XP_016860138.1|refseq:XP_016860140.1|refseq:XP_016860141.1|dip:DIP-59851N|refseq:NP_001159435.1|refseq:NP_001189364.1|refseq:NP_008851.3|ensembl:ENSP00000303540|ensembl:ENST00000375405|ensembl:ENSP00000364554|ensembl:ENST00000409050|ensembl:ENSP00000386312|ensembl:ENST00000635750|ensembl:ENSP00000490799|ensembl:ENST00000637988|ensembl:ENSP00000490780|ensembl:ENSP00000501589|refseq:NP_001159436.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Ec9/LYw0XQpCjCbKGtVsJ6t7AZI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NVC6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9UHV7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6P2E9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q13823 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y4W2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q93074 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005111.2|ensembl:ENSG00000184634(gene)|ensembl:ENST00000374080(transcript)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q93074|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|dip:DIP-31459N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9BQG0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-676973|intact:EBI-2559619|uniprotkb:Q86VM3|uniprotkb:Q9BW49|uniprotkb:Q9P0V5|uniprotkb:Q9UF99|ensembl:ENSP00000254718 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:mbb1a_human(display_long)|uniprotkb:MYBBP1A(gene name)|psi-mi:MYBBP1A(display_short)|uniprotkb:P160(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001099008.1|refseq:NP_055335.2|ensembl:ENST00000254718(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042254"(ribosome biogenesis)|ensembl:ENSG00000132382(gene)|go:"GO:0042564"(NLS-dependent protein nuclear import complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070888"(E-box binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR007015(DNA polymerase V)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BQG0|reactome:R-HSA-5250924 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:ScabTPXvbX/5VRsnaRQXUIlANow9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P17066 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q06787 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:+iN/J/MbxTcRwgDezYseEDwLep49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:A0AV96 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2823850|uniprotkb:B5MED4|uniprotkb:A0PJK2|uniprotkb:Q8NI53|uniprotkb:Q9NXG3|uniprotkb:Q8NI52|ensembl:ENSP00000295971|ensembl:ENSP00000371212 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm47_human(display_long)|uniprotkb:RBM47(gene name)|psi-mi:RBM47(display_short)|uniprotkb:RNA-binding motif protein 47(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011512006.1|refseq:XP_011512009.1|refseq:XP_011512010.1|refseq:NP_001092104.1|refseq:NP_061900.2|refseq:XP_016863793.1|refseq:XP_016863794.1|refseq:XP_016863795.1|refseq:XP_016863796.1|refseq:XP_016863797.1|refseq:XP_016863799.1|ensembl:ENSG00000163694(gene)|ensembl:ENST00000295971(transcript)|ensembl:ENST00000381793(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0016554"(cytidine to uridine editing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034440|interpro:IPR034442|interpro:IPR034445|interpro:IPR035979|rcsb pdb:2DIS|refseq:XP_005248160.1|refseq:XP_005248164.1|refseq:XP_005248165.1|refseq:XP_005248166.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:GbC2ij2c3BFt+oF2xgADnSytKV49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P30048 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q5SSJ5 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880687|ensembl:ENSP00000312625|ensembl:ENSP00000403039|uniprotkb:Q5SWC6|uniprotkb:Q6PIM9|uniprotkb:B3KMZ8|uniprotkb:A8K5D7|uniprotkb:Q8NDF0|uniprotkb:Q05BI0|uniprotkb:B4E210|uniprotkb:A6NI71|uniprotkb:Q9UHY0|uniprotkb:Q5SSJ6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hp1b3_human(display_long)|uniprotkb:HP1BP3(gene name)|psi-mi:HP1BP3(display_short)|uniprotkb:Protein HP1-BP74(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000127483(gene)|ensembl:ENST00000312239(transcript)|ensembl:ENST00000438032(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016607"(nuclear speck)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097298"(regulation of nucleus size)|interpro:IPR005818(Histone H1/H5)|interpro:IPR033061|interpro:IPR036388|interpro:IPR036390|mint:Q5SSJ5|rcsb pdb:2RQP|go:"GO:0005694"(chromosome)|refseq:XP_016856882.1|refseq:XP_016856883.1|refseq:XP_011539834.1|refseq:XP_011539835.1|refseq:XP_011539836.1|refseq:NP_057371.2|refseq:XP_005245932.1|refseq:XP_005245933.1|refseq:XP_005245934.1|refseq:XP_005245935.1|refseq:XP_005245936.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:kLFithZZv+Qn9YLElEnX81awKDw9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q969Q0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8IY81 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-744088|uniprotkb:Q8N3A3|uniprotkb:Q8WXX1|uniprotkb:Q9BWM4|uniprotkb:Q9NXT6|uniprotkb:D3DU22|uniprotkb:B2RCA5|ensembl:ENSP00000396673 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:spb1_human(display_long)|uniprotkb:FTSJ3(gene name)|psi-mi:FTSJ3(display_short)|uniprotkb:SB92(orf name)|uniprotkb:Protein ftsJ homolog 3(gene name synonym)|uniprotkb:Putative rRNA methyltransferase 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060117.3|interpro:IPR015507(Ribosomal RNA methyltransferase J)|interpro:IPR024576|interpro:IPR028589|interpro:IPR029063|mint:Q8IY81|reactome:R-HSA-6791226|ensembl:ENSG00000108592(gene)|ensembl:ENST00000427159(transcript)|go:"GO:0000453"(enzyme-directed rRNA 2'-O-methylation)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000466"("maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008650"("rRNA (uridine-2'-O-)-methyltransferase activity")|go:"GO:0016435"("rRNA (guanine) methyltransferase activity")|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0031167"(rRNA methylation)|go:"GO:0062105"(RNA 2'-O-methyltransferase activity)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR012920(Spb1, C-terminal) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:KIeyMWn9Zktm5lV7XI7v2bRA8og9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8N9T8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-724923|uniprotkb:Q2M1R5|uniprotkb:Q2M1R7|uniprotkb:Q7L5J7|uniprotkb:Q96G92|uniprotkb:Q9BU50|uniprotkb:Q9H6I1|uniprotkb:Q9H978|ensembl:ENSP00000320917 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:kri1_human(display_long)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_075384.3|ensembl:ENSG00000129347(gene)|ensembl:ENST00000312962(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|mint:Q8N9T8 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:sIRmrP/c3tSmEAj1usRGN3R3Bh09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O75569 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-713955|ensembl:ENSP00000318176|uniprotkb:Q53G24|uniprotkb:Q6X7T5|uniprotkb:Q8NDK4|uniprotkb:A8K3I6 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:prkra_human(display_long)|uniprotkb:Protein activator of the interferon-induced protein kinase(gene name synonym)|uniprotkb:PKR-associated protein X(gene name synonym)|uniprotkb:PKR-associating protein X(gene name synonym)|uniprotkb:HSD-14(orf name)|uniprotkb:PRKRA(gene name)|psi-mi:PRKRA(display_short)|uniprotkb:RAX(gene name synonym)|uniprotkb:PACT(gene name synonym)|uniprotkb:HSD14(orf name)|uniprotkb:Protein kinase, interferon-inducible double-stranded RNA-dependent activator(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006955"(immune response)|go:"GO:0008047"(enzyme activator activity)|ensembl:ENSG00000180228(gene)|ensembl:ENST00000325748(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR032478|interpro:IPR033363|interpro:IPR044465|interpro:IPR044466|interpro:IPR044467|mint:O75569|rcsb pdb:2DIX|reactome:R-HSA-203927|reactome:R-HSA-426486|refseq:NP_001132989.1|refseq:NP_001132990.1|refseq:NP_003681.1|dip:DIP-41809N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:tZfziopZlC+1d3De97G3kDY+Tog9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P47914 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8IYT4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1044332|ensembl:ENSP00000348478|ensembl:ENSP00000508137 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:katl2_human(display_long)|uniprotkb:p60 katanin-like 2(gene name synonym)|uniprotkb:KATNAL2(gene name)|psi-mi:KATNAL2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_112593.2|refseq:XP_006722617.1|ensembl:ENSG00000167216(gene)|ensembl:ENST00000356157(transcript)|ensembl:ENST00000683218(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0031122"(cytoplasmic microtubule organization)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR027417|interpro:IPR027497|interpro:IPR041569 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:2k+M09zbS1SB029s47A1CpuD+ZY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62753 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:beDuXCIqL99V9JlVfpzx7MdpH689606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96PK6 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-954272|ensembl:ENSP00000311747|uniprotkb:O75932|uniprotkb:Q53GV1|uniprotkb:Q68DQ9|uniprotkb:Q96PK5|uniprotkb:B3KMN4|uniprotkb:Q2PYN1|uniprotkb:D6RGD8|uniprotkb:B0LM41|intact:EBI-16430855|intact:EBI-16472484 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm14_human(display_long)|uniprotkb:RNA-binding motif protein 14(gene name synonym)|uniprotkb:RRM-containing coactivator activator/modulator(gene name synonym)|uniprotkb:Synaptotagmin-interacting protein(gene name synonym)|uniprotkb:RBM14(gene name)|psi-mi:RBM14(display_short)|uniprotkb:SIP(gene name synonym)|uniprotkb:Paraspeckle protein 2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000239306(gene)|ensembl:ENST00000310137(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0009725"(response to hormone)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|go:"GO:0098534"(centriole assembly)|interpro:IPR035979|mint:Q96PK6|rcsb pdb:2DNP|reactome:R-HSA-8941326|refseq:NP_001185765.1|refseq:NP_006319.1|ensembl:ENSP00000311747|ensembl:ENST00000393979|ensembl:ENSP00000377548|ensembl:ENST00000409738|ensembl:ENSP00000386995|refseq:NP_001185766.1|refseq:NP_001185774.1|dip:DIP-50126N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Q0UBl2qmfwQTPwUQ7ZDwGIMOYoA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92552 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2211879|uniprotkb:Q6P1S1|uniprotkb:B4DRT2|ensembl:ENSP00000261413 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt27_human(display_long)|uniprotkb:MRPS27(gene name)|psi-mi:MRPS27(display_short)|uniprotkb:KIAA0264(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS27(gene name synonym)|uniprotkb:Mitochondrial ribosomal protein S27(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001273677.1|refseq:NP_055899.2|dip:DIP-44136N|ensembl:ENSG00000113048(gene)|ensembl:ENST00000261413(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019843"(rRNA binding)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019266|interpro:IPR034913|mint:Q92552|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:reHIDm6Of3ERJMBRxVlVntHyRlY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96PV0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2682386|uniprotkb:Q9UGE2|uniprotkb:A8MQC4|uniprotkb:Q8TCS2|uniprotkb:A2AB17|uniprotkb:A2BEL6|uniprotkb:A2BEL7|intact:EBI-28975552|ensembl:ENSP00000414259|ensembl:ENSP00000486463|ensembl:ENSP00000496007 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:sygp1_human(display_long)|uniprotkb:KIAA1938(gene name synonym)|uniprotkb:Neuronal RasGAP(gene name synonym)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)|uniprotkb:SYNGAP1(gene name)|psi-mi:SYNGAP1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000628646|ensembl:ENSP00000486431|ensembl:ENSP00000486463|ensembl:ENSP00000496007|ensembl:ENST00000395071|ensembl:ENSP00000378509|ensembl:ENST00000414753|ensembl:ENSP00000407995|ensembl:ENST00000418600|ensembl:ENSP00000403636|ensembl:ENST00000428982|ensembl:ENSP00000412475|ensembl:ENSP00000414259|refseq:NP_006763.2|refseq:NP_001123538.1|ensembl:ENSG00000197283(gene)|ensembl:ENSG00000227460(gene)|ensembl:ENST00000455687(transcript)|ensembl:ENST00000629380(transcript)|ensembl:ENST00000646630(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR035892|interpro:IPR037779|interpro:IPR039360|mint:Q96PV0|reactome:R-HSA-5658442 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:3Uq2PiuV/QQyjjPbPJS+CgN8+W89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q15459 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96DU9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880076|ensembl:ENSP00000308012|uniprotkb:Q5JQF4|uniprotkb:Q9UFE5|uniprotkb:Q6P529|uniprotkb:A8K240 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pabp5_human(display_long)|uniprotkb:PABPC5(gene name)|psi-mi:PABPC5(display_short)|uniprotkb:PABP5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000174740(gene)|ensembl:ENST00000312600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0010494"(cytoplasmic stress granule)|refseq:NP_543022.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:IK1onIpa3e6rg71uj0b+i4i9o/k9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:A0A024RC46 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2877714 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:a0a024rc46_human(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein A1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:hCG_2020860(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|uniprotkb:P0C7M2(uniprot-removed-ac)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:HMnm+Sl1fr93GpUitmuGDYeRzCQ9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P51610 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9P2M7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-79537|intact:EBI-28986579|ensembl:ENSP00000271636|uniprotkb:Q5T386|uniprotkb:Q9NR25|uniprotkb:A6H8L3|uniprotkb:A7MD22 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cing_human(display_long)|uniprotkb:CGN(gene name)|psi-mi:CGN(display_short)|uniprotkb:KIAA1319(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000143375(gene)|ensembl:ENST00000271636(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016459"(myosin complex)|go:"GO:0030054"(cell junction)|go:"GO:0045296"(cadherin binding)|interpro:IPR002928(Myosin tail)|mint:Q9P2M7|reactome:R-HSA-2173791|refseq:NP_065821.1|ensembl:ENSP00000271636|refseq:XP_005245422.1|dip:DIP-30947N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:RJ4soprXOGUAlMLVIikuoeMs3v09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q13243 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-720503|uniprotkb:O14797|uniprotkb:Q16662|uniprotkb:Q49AD6|uniprotkb:Q6FGE0|ensembl:ENSP00000377892|ensembl:ENSP00000451088|ensembl:ENSP00000452123 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:srsf5_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP40(gene name synonym)|uniprotkb:Delayed-early protein HRS(gene name synonym)|uniprotkb:SRSF5(gene name)|psi-mi:SRSF5(display_short)|uniprotkb:HRS(gene name synonym)|uniprotkb:SRP40(gene name synonym)|uniprotkb:SFRS5(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0003729"(mRNA binding)|refseq:NP_001034554.1|refseq:NP_008856.2|refseq:NP_001307143.1|dip:DIP-46894N|ensembl:ENSG00000100650(gene)|ensembl:ENST00000394366(transcript)|ensembl:ENST00000553521(transcript)|ensembl:ENST00000557154(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q13243|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|go:"GO:0005654"(nucleoplasm)|reactome:R-HSA-73856 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:q+kwVNXjDcA8o9hJ+BDF0S5ZSlY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96AG4 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P36776 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-357448|ensembl:ENSP00000353826|intact:EBI-1054513|uniprotkb:D6W635|uniprotkb:E5KMH8|uniprotkb:P36777|uniprotkb:Q8N8K8|uniprotkb:Q9UQ95|uniprotkb:B3KPH8|uniprotkb:F5GZ27|intact:EBI-10964236 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lonm_human(display_long)|uniprotkb:LONHs(gene name synonym)|uniprotkb:PRSS15(gene name synonym)|uniprotkb:LONP1(gene name)|psi-mi:LONP1(display_short)|uniprotkb:Lon protease-like protein(gene name synonym)|uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)|uniprotkb:Serine protease 15(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001263408.1|go:"GO:0070407"(oxidation-dependent protein catabolic process)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027503|mint:P36776|rcsb pdb:2X36|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070182"(DNA polymerase binding)|rcsb pdb:6WYS|rcsb pdb:6WZV|rcsb pdb:6X1M|rcsb pdb:6X27|rcsb pdb:7KRZ|rcsb pdb:7KSL|rcsb pdb:7KSM|rcsb pdb:7NFY|rcsb pdb:7NG4|rcsb pdb:7NG5|rcsb pdb:7NGC|rcsb pdb:7NGF|rcsb pdb:7NGL|rcsb pdb:7NGP|rcsb pdb:7NGQ|ensembl:ENSG00000196365(gene)|ensembl:ENST00000360614(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0009725"(response to hormone)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|refseq:NP_001263409.1|refseq:NP_004784.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:quAPz1dZK2XdoE6WMjQJwFtx53o9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P22528 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P43307 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-714168|uniprotkb:A8K685|uniprotkb:Q9TNQ8|uniprotkb:Q53GX2|uniprotkb:Q53H19|uniprotkb:Q5TAM3|uniprotkb:Q6IB43|uniprotkb:Q8NBH9|uniprotkb:Q96IA2|uniprotkb:Q9UN49|ensembl:ENSP00000244763 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ssra_human(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:SSR1(gene name)|psi-mi:SSR1(display_short)|uniprotkb:TRAPA(gene name synonym)|uniprotkb:PSEC0262(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_003135.2|ensembl:ENSG00000124783(gene)|ensembl:ENST00000244763(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit")|mint:P43307|reactome:R-HSA-1799339|reactome:R-HSA-381038|refseq:NP_001278937.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:OhI1z1wbH8LEZaiv+OLChzMvT+A9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:A6NHQ2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880232|ensembl:ENSP00000473383|uniprotkb:R4GMW7 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:fbll1_human(display_long)|uniprotkb:FBLL1(gene name)|psi-mi:FBLL1(display_short)|uniprotkb:Protein-glutamine methyltransferase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENST00000338333(transcript)|go:"GO:0000494"(box C/D RNA 3'-end processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008649"(rRNA methyltransferase activity)|go:"GO:0015030"(Cajal body)|go:"GO:0031167"(rRNA methylation)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:1990258"(histone glutamine methylation)|go:"GO:1990259"(histone-glutamine methyltransferase activity)|interpro:IPR000692(Fibrillarin)|interpro:IPR020813|interpro:IPR029063|ensembl:ENSG00000188573(gene) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:SXuNpiRJofinc5yUsg+MIjFIeW09606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P14136 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-744302|uniprotkb:Q53H98|uniprotkb:Q5D055|uniprotkb:Q6ZQS3|uniprotkb:Q7Z5J6|uniprotkb:Q7Z5J7|uniprotkb:Q96KS4|uniprotkb:Q96P18|uniprotkb:Q9UFD0|uniprotkb:B2RD44|uniprotkb:D3DX59|intact:EBI-3909365|uniprotkb:E9PAX3|ensembl:ENSP00000466598|uniprotkb:A7REI1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:gfap_human(display_long)|uniprotkb:GFAP(gene name)|psi-mi:GFAP(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001124491.1|refseq:NP_001229305.1|refseq:NP_002046.1|ensembl:ENSG00000131095(gene)|ensembl:ENST00000588735(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044297"(cell body)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P14136|rcsb pdb:6A9P|reactome:R-HSA-1251985|reactome:R-HSA-9613829 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Pz4JW0WjMjBYILTDSX9jUmMqWhg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P82650 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6P2C8 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q14247 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q02543 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-350523|ensembl:ENSP00000222247 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl18a_human(display_long)|uniprotkb:RPL18A(gene name)|psi-mi:RPL18A(display_short)|uniprotkb:Large ribosomal subunit protein eL20(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_000971.1|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:Q02543|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|go:"GO:0097327"(response to antineoplastic agent)|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|ensembl:ENSG00000105640(gene)|ensembl:ENST00000222247(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|rcsb pdb:6ZME|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:O9XdW7Let2GcJpJLVuUtatVVv1I9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q2TAZ0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q86WR7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880603|ensembl:ENSP00000277570|uniprotkb:Q5W0K2|uniprotkb:Q6PJC8|uniprotkb:Q5W0K1|uniprotkb:Q8N317|uniprotkb:Q5W0J9|uniprotkb:Q5W0K0|uniprotkb:D3DRR8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:prsr2_human(display_long)|uniprotkb:PROSER2(gene name)|psi-mi:PROSER2(display_short)|uniprotkb:C10orf47(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000148426(gene)|ensembl:ENST00000277570(transcript)|refseq:XP_016871517.1|refseq:XP_011517740.1|refseq:NP_694988.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:paVZi74BuB0v/0ssIL4eb/7CW009606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6UX04 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2214108|uniprotkb:O60529|uniprotkb:O60530|uniprotkb:Q96EM3|ensembl:ENSP00000370460 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cwc27_human(display_long)|uniprotkb:SDCCAG10(gene name synonym)|uniprotkb:CWC27(gene name)|psi-mi:CWC27(display_short)|uniprotkb:Serologically defined colon cancer antigen 10(gene name synonym)|uniprotkb:Antigen NY-CO-10(gene name synonym)|uniprotkb:UNQ438/PRO871(orf name)|uniprotkb:Probable inactive peptidyl-prolyl cis-trans isomerase CWC27 homolog(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001284573.1|refseq:NP_001284574.1|refseq:NP_005860.2|ensembl:ENSG00000153015(gene)|ensembl:ENST00000381070(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|interpro:IPR044666|rcsb pdb:2HQ6|rcsb pdb:4R3E|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6YVH|rcsb pdb:7DVQ|reactome:R-HSA-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:4FP6Whtw50x+g8DoR0ocAjEaQmk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P61158 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H9J2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-713619|uniprotkb:Q53S16|uniprotkb:Q6IA62|uniprotkb:Q9H821|ensembl:ENSP00000258383|intact:EBI-21356011 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rm44_human(display_long)|uniprotkb:MRPL44(gene name)|psi-mi:MRPL44(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL44(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000135900(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR044444|mint:Q9H9J2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|ensembl:ENST00000258383(transcript)|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_075066.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:YNUNu4UGyhAuaSChEzFXCw2k7wk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92901 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2514377|ensembl:ENSP00000268661 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rl3l_human(display_long)|uniprotkb:RPL3L(gene name)|psi-mi:RPL3L(display_short)|uniprotkb:Large ribosomal subunit protein uL3-like(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000140986(gene)|ensembl:ENST00000268661(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_005052.1|ensembl:ENSP00000268661 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:hG1wpRH7DNIbNB4zCONsF22W3zc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P60709 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q16630 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q709F0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880718|ensembl:ENSP00000264990|uniprotkb:Q8WUT6|uniprotkb:Q08AF0|uniprotkb:Q658Y2|uniprotkb:Q658N9|uniprotkb:Q6ZND2|uniprotkb:Q9H9R3 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:acd11_human(display_long)|uniprotkb:ACAD11(gene name)|psi-mi:ACAD11(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000240303(gene)|ensembl:ENST00000264990(transcript)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|interpro:IPR041726|mint:Q709F0|rcsb pdb:2WBI|reactome:R-HSA-77289|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|refseq:NP_115545.3 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:Qknz1ZNcvX0q/3f5TuGQkJ6oHSk9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y2H0 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-722139|uniprotkb:Q5QPG4|uniprotkb:Q5T2Y4|uniprotkb:Q5T2Y5|uniprotkb:Q9H137|uniprotkb:Q9H138|uniprotkb:Q9H1L7|uniprotkb:E1P5T5|ensembl:ENSP00000341633|ensembl:ENSP00000363014 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:dlgp4_human(display_long)|uniprotkb:SAPAP4(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 4(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 4(gene name synonym)|uniprotkb:DLGAP4(gene name)|psi-mi:DLGAP4(display_short)|uniprotkb:DAP4(gene name synonym)|uniprotkb:KIAA0964(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001035951.1|refseq:NP_055717.2|refseq:NP_892118.1|refseq:XP_011526990.1|ensembl:ENSG00000080845(gene)|ensembl:ENST00000339266(transcript)|ensembl:ENST00000373907(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0023052"(signaling)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099572"(postsynaptic specialization)|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030527|mint:Q9Y2H0|reactome:R-HSA-6794361 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:i9/U52HQi00xnRUtJN0VZ0oXXwY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96ST3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P98175 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|uniprotkb:A0A0A0MR66|ensembl:ENSP00000366829 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_005667.2|refseq:NP_690595.1|refseq:NP_001191397.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|ensembl:ENSG00000182872(gene)|ensembl:ENST00000377604(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O00159 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-350423|uniprotkb:Q6NVJ7|intact:EBI-1045431|uniprotkb:Q86Y95|uniprotkb:Q4LE56|ensembl:ENSP00000496954 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:myo1c_human(display_long)|uniprotkb:MYO1C(gene name)|psi-mi:MYO1C(display_short)|uniprotkb:Myosin I beta(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0005829"(cytosol)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|refseq:NP_001074248.1|refseq:NP_001074419.1|refseq:NP_203693.3|ensembl:ENSG00000197879(gene)|ensembl:ENST00000648651(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O00159|rcsb pdb:4BYF|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-5250924|reactome:R-HSA-9662360|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|reactome:R-HSA-9662361|reactome:R-HSA-9664422|dip:DIP-33109N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:g6wQN0OVKjd3T1kOebWFcqWNzNA9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96EY7 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q96G01 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1104509|uniprotkb:O43892|uniprotkb:O43893|uniprotkb:A8K2C3|uniprotkb:F8W113|ensembl:ENSP00000498700 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:bicd1_human(display_long)|uniprotkb:BICD1(gene name)|psi-mi:BICD1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001003398.1|refseq:NP_001705.2|ensembl:ENSG00000151746(gene)|ensembl:ENST00000652176(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008298"(intracellular mRNA localization)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034452"(dynactin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072385"(minus-end-directed organelle transport along microtubule)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1900276"(regulation of proteinase activated receptor activity)|go:"GO:1900737"(negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:1904781"(positive regulation of protein localization to centrosome)|interpro:IPR018477|mint:Q96G01|reactome:R-HSA-6811436 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:/k7T2ySwKMmpWORAV8jUfsEr+3k9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H0E9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-769266|uniprotkb:O43178|uniprotkb:Q15355|uniprotkb:Q58AB0|uniprotkb:Q59GN0|uniprotkb:Q969M9|intact:EBI-28979295|ensembl:ENSP00000254900 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:brd8_human(display_long)|uniprotkb:p120(gene name synonym)|uniprotkb:Skeletal muscle abundant protein 2(gene name synonym)|uniprotkb:Skeletal muscle abundant protein(gene name synonym)|uniprotkb:Thyroid hormone receptor coactivating protein of 120 kDa(gene name synonym)|uniprotkb:BRD8(gene name)|psi-mi:BRD8(display_short)|uniprotkb:SMAP(gene name synonym)|uniprotkb:SMAP2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001157798.1|refseq:NP_006687.3|refseq:NP_631938.1|ensembl:ENST00000230901|ensembl:ENSP00000230901|ensembl:ENSP00000254900|ensembl:ENST00000411594|ensembl:ENSP00000394330|refseq:NP_001287890.1|refseq:NP_001287891.1|refseq:NP_001287895.1|dip:DIP-31762N|ensembl:ENSG00000112983(gene)|ensembl:ENST00000254900(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001487(Bromodomain)|interpro:IPR036427|interpro:IPR037966|interpro:IPR038002|mint:Q9H0E9|reactome:R-HSA-3214847|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth) psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:RUJbvq7VAMg7fzpCT4Hs6/FPej49606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q99460 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P62854 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 intact:EBI-2880675 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 - psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pabpcp2(display_short)|psi-mi:EBI-2880675(display_long) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 uniprotkb:Q6NV95(uniprot-removed-ac) psi-mi:"MI:0469"(intact) - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 - intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y446 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880227|ensembl:ENSP00000331678|uniprotkb:F8J390|uniprotkb:Q53EX8 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pkp3_human(display_long)|uniprotkb:PKP3(gene name)|psi-mi:PKP3(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000184363(gene)|ensembl:ENST00000331563(transcript)|go:"GO:0002159"(desmosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006417"(regulation of translation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0001533"(cornified envelope)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028434|interpro:IPR028435|mint:Q9Y446|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|refseq:NP_001289958.1|refseq:NP_009114.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:zGNbdze5MA5Mnf8m9IWZsxAPjAQ9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O43719 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-720468|uniprotkb:Q59G06|uniprotkb:Q99730|uniprotkb:D3DWG9|intact:EBI-28971035|ensembl:ENSP00000218364|ensembl:ENSP00000442699 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:htsf1_human(display_long)|uniprotkb:HTATSF1(gene name)|psi-mi:HTATSF1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSP00000218364|ensembl:ENSP00000442699|refseq:NP_001156752.1|refseq:NP_055315.2|refseq:XP_005262461.1|dip:DIP-42095N|ensembl:ENSG00000102241(gene)|ensembl:ENST00000218364(transcript)|ensembl:ENST00000535601(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0019079"(viral genome replication)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034392|interpro:IPR034393|interpro:IPR035979|mint:O43719|rcsb pdb:2DIT|rcsb pdb:6N3D|rcsb pdb:6N3E|rcsb pdb:6N3F|rcsb pdb:6NSX|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:PttL+7D+505QAmcHRGNsc40haPY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9NX58 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q8WWY3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1567797|uniprotkb:Q8N7F9|uniprotkb:Q9H271|uniprotkb:Q9Y439|uniprotkb:Q17RB4|intact:EBI-10177194|uniprotkb:F1T0A5|uniprotkb:E7ESA8|uniprotkb:F1T0A4|ensembl:ENSP00000324122|ensembl:ENSP00000483929 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:prp31_human(display_long)|uniprotkb:Pre-mRNA-processing factor 31(gene name synonym)|uniprotkb:U4/U6 snRNP 61 kDa protein(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-99(gene name synonym)|uniprotkb:PRPF31(gene name)|psi-mi:PRPF31(display_short)|uniprotkb:PRP31(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:XP_006723200.1|refseq:NP_056444.3|ensembl:ENSG00000105618(gene)|ensembl:ENSG00000275885(gene)|ensembl:ENST00000321030(transcript)|ensembl:ENST00000613693(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|interpro:IPR002687(Pre-mRNA processing ribonucleoprotein, binding region)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR012976(NOSIC)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070990"(snRNP binding)|interpro:IPR019175|interpro:IPR027105|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071166"(ribonucleoprotein complex localization)|interpro:IPR036070|interpro:IPR042239|mint:Q8WWY3|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:NsXY3tY7Y2EEK8rxoisqlfpzuf89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O43379 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-714790|uniprotkb:Q63HP9|uniprotkb:Q659D7|uniprotkb:Q8NBF7|uniprotkb:Q96AD9|intact:EBI-2563293|ensembl:ENSP00000270301 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:wdr62_human(display_long)|uniprotkb:WDR62(gene name)|psi-mi:WDR62(display_short)|uniprotkb:C19orf14(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007099"(centriole replication)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0034451"(centriolar satellite)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR024977|interpro:IPR036322|mint:O43379|go:"GO:0005813"(centrosome)|ensembl:ENSG00000075702(gene)|ensembl:ENST00000270301(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|refseq:NP_001077430.1|refseq:NP_775907.4|refseq:XP_016882154.1|dip:DIP-56792N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:bKUivd80luQPFZHsU9mDdwyGwi89606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q92804 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2255091|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94|ensembl:ENSP00000474096|ensembl:ENSP00000480040 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|ensembl:ENSG00000270647(gene)|ensembl:ENSG00000276833(gene)|ensembl:ENST00000605844(transcript)|ensembl:ENST00000617382(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR034875|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P46781 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9H361 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1055272|uniprotkb:Q8NHV0|uniprotkb:Q9H086|ensembl:ENSP00000281589 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:pabp3_human(display_long)|uniprotkb:"Testis-specific poly(A)-binding protein"(gene name synonym)|uniprotkb:PABPC3(gene name)|psi-mi:PABPC3(display_short)|uniprotkb:PABP3(gene name synonym)|uniprotkb:PABPL3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_112241.2|ensembl:ENSG00000151846(gene)|ensembl:ENST00000281589(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q9H361|rcsb pdb:2D9P|rcsb pdb:4IVE psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:g/tDJDBcBC+s8P6LGDIwgZO8HHY9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P82675 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1054287|uniprotkb:Q96LJ6|uniprotkb:Q9BWI4|uniprotkb:Q9BYC4|uniprotkb:Q4ZFY5|ensembl:ENSP00000272418 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rt05_human(display_long)|uniprotkb:MRPS5(gene name)|psi-mi:MRPS5(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS5m(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_114108.1|ensembl:ENSG00000144029(gene)|ensembl:ENST00000272418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR018192|interpro:IPR020568|mint:P82675|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6RW5|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:l+aZgmDVWWimuUiH4IS4FG1cwlQ9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:O43593 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6PJG2 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2795569|uniprotkb:Q6PK13|uniprotkb:Q6PK59|uniprotkb:Q6ZS23|intact:EBI-28972055|ensembl:ENSP00000286523|ensembl:ENSP00000377634 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:mdeas_human(display_long)|uniprotkb:MIDEAS(gene name)|psi-mi:MIDEAS(display_short)|uniprotkb:C14orf117(gene name synonym)|uniprotkb:C14orf43(gene name synonym)|uniprotkb:ELM2 and SANT domain-containing protein 1(gene name synonym)|uniprotkb:ELMSAN1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSP00000286523|ensembl:ENSP00000377634|refseq:NP_001036783.1|refseq:NP_919254.2|ensembl:ENSG00000156030(gene)|ensembl:ENST00000286523(transcript)|ensembl:ENST00000394071(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|rcsb pdb:6Z2J|rcsb pdb:6Z2K psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:wZyVPfF6zuF0ObDUtE0t0e0IK1M9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q9Y6Q9 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-81196|uniprotkb:Q5JYD9|uniprotkb:Q5JYE0|uniprotkb:Q9BR49|uniprotkb:Q9UPC9|uniprotkb:Q9UPG4|uniprotkb:Q9UPG7|ensembl:ENSP00000361066|uniprotkb:A4LAZ5|uniprotkb:Q0VF45 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:ncoa3_human(display_long)|uniprotkb:NCOA3(gene name)|psi-mi:NCOA3(display_short)|uniprotkb:AIB1(gene name synonym)|uniprotkb:RAC3(gene name synonym)|uniprotkb:Thyroid hormone receptor activator molecule 1(gene name synonym)|uniprotkb:Receptor-associated coactivator 3(gene name synonym)|uniprotkb:BHLHE42(gene name synonym)|uniprotkb:Steroid receptor coactivator protein 3(gene name synonym)|uniprotkb:CBP-interacting protein(gene name synonym)|uniprotkb:Amplified in breast cancer 1 protein(gene name synonym)|uniprotkb:ACTR(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 42(gene name synonym)|uniprotkb:TRAM1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001167559.1|refseq:NP_006525.2|refseq:NP_858045.1|ensembl:ENSG00000124151(gene)|ensembl:ENST00000371998(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035624"(receptor transactivation)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028818|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q9Y6Q9|rcsb pdb:1KBH|rcsb pdb:3L3X|rcsb pdb:3L3Z|rcsb pdb:6ES7|rcsb pdb:6SQC|reactome:R-HSA-1989781|reactome:R-HSA-381340|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-9018519|dip:DIP-30876N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:HWcRyNPgZ0dLD9cb5iuiarsGG8E9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q6ZSC3 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-2880658|ensembl:ENSP00000331211|uniprotkb:B2RMT5 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:rbm43_human(display_long)|uniprotkb:RBM43(gene name)|psi-mi:RBM43(display_short)|uniprotkb:C2orf38(gene name synonym)|uniprotkb:RNA-binding motif protein 43(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 ensembl:ENSG00000184898(gene)|ensembl:ENST00000331426(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034463|interpro:IPR035979|refseq:NP_940959.1 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:olAw5Soo87qoOVcr7HQgeaOVogw9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:Q99996 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-1048311|uniprotkb:O14869|uniprotkb:O43355|uniprotkb:O94895|uniprotkb:Q75N20|uniprotkb:Q9UQH3|uniprotkb:Q9UQQ4|uniprotkb:Q9Y6B8|uniprotkb:A4D1F0|uniprotkb:Q9Y6Y2|uniprotkb:A4D1F2|uniprotkb:A4D1F4|ensembl:ENSP00000348573 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:akap9_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 9(gene name synonym)|uniprotkb:A-kinase anchor protein 450 kDa(gene name synonym)|uniprotkb:A-kinase anchor protein 350 kDa(gene name synonym)|uniprotkb:AKAP 120-like protein(gene name synonym)|uniprotkb:Protein hyperion(gene name synonym)|uniprotkb:Protein yotiao(gene name synonym)|uniprotkb:Centrosome- and Golgi-localized PKN-associated protein(gene name synonym)|uniprotkb:AKAP9(gene name)|psi-mi:AKAP9(display_short)|uniprotkb:AKAP350(gene name synonym)|uniprotkb:AKAP450(gene name synonym)|uniprotkb:KIAA0803(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_005742.4|refseq:NP_671714.1|ensembl:ENSG00000127914(gene)|ensembl:ENST00000356239(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007165"(signal transduction)|go:"GO:0007194"(negative regulation of adenylate cyclase activity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0034705"(potassium channel complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044307"(dendritic branch)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR005539(ELK)|interpro:IPR019528|interpro:IPR028745|mint:Q99996|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5576890|reactome:R-HSA-5576893|reactome:R-HSA-5620912|reactome:R-HSA-6802952|reactome:R-HSA-8854518|ensembl:ENSP00000348573|ensembl:ENST00000680766|ensembl:ENSP00000505204|dip:DIP-29942N psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:LQUNbTHUgEsjayFEZvczC4e90Nw9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q92731 uniprotkb:P12814 intact:EBI-78505|uniprotkb:A8K8K5|uniprotkb:O60608|uniprotkb:O60685|uniprotkb:O60702|uniprotkb:O60703|uniprotkb:O75583|uniprotkb:O75584|uniprotkb:Q86Z31|uniprotkb:Q9UEV6|uniprotkb:Q9UHD3|uniprotkb:Q9UQK9|uniprotkb:Q0MWT5|uniprotkb:Q0MWT6|uniprotkb:G3V5M5|ensembl:ENSP00000343925 intact:EBI-351710|uniprotkb:Q9BTN1|uniprotkb:Q1HE25|uniprotkb:B7TY16|intact:EBI-3866221|uniprotkb:B3V8S3|uniprotkb:B4DHH3|ensembl:ENSP00000193403 psi-mi:esr2_human(display_long)|uniprotkb:ESR2(gene name)|psi-mi:ESR2(display_short)|uniprotkb:ESTRB(gene name synonym)|uniprotkb:NR3A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group A member 2(gene name synonym) psi-mi:actn1_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Nassa et al. (2010) imex:IM-13781|pubmed:21182203 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2880601|imex:IM-13781-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035365.1|refseq:NP_001201831.1|refseq:NP_001428.1|refseq:NP_001258805.1|refseq:NP_001258806.1|refseq:NP_001278641.1|refseq:NP_001278652.1|refseq:XP_016876568.1|refseq:XP_016876569.1|refseq:XP_016876570.1|refseq:XP_016876571.1|refseq:XP_016876572.1|refseq:XP_016876573.1|dip:DIP-5966N|ensembl:ENSG00000140009(gene)|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2FSZ|rcsb pdb:2GIU|rcsb pdb:2I0G|rcsb pdb:2JJ3|rcsb pdb:2NV7|rcsb pdb:2QTU|rcsb pdb:2YJD|rcsb pdb:2YLY|rcsb pdb:2Z4B|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:4J24|rcsb pdb:4J26|rcsb pdb:4ZI1|rcsb pdb:5TOA|reactome:R-HSA-1257604|reactome:R-HSA-2219530|reactome:R-HSA-383280|reactome:R-HSA-6811558|reactome:R-HSA-8939211|reactome:R-HSA-9009391|ensembl:ENST00000341099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030284"(estrogen receptor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021064|interpro:IPR024178|interpro:IPR028355|interpro:IPR035500|rcsb pdb:1L2J|rcsb pdb:1NDE|rcsb pdb:1QKM|rcsb pdb:1U3Q|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1U9E|rcsb pdb:1X76 refseq:NP_001093.1|refseq:NP_001123477.1|refseq:NP_001123476.1|dip:DIP-33184N|ensembl:ENSG00000072110(gene)|ensembl:ENST00000193403(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P12814|rcsb pdb:2EYI|rcsb pdb:2EYN|rcsb pdb:2N8Y|rcsb pdb:2N8Z|reactome:R-HSA-114608|reactome:R-HSA-3000170|reactome:R-HSA-373753|reactome:R-HSA-446388|reactome:R-HSA-9013405|reactome:R-HSA-9013418|reactome:R-HSA-9035034 psi-mi:"MI:0469"(intact) - - figure legend:Table S2|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mcf7)|taxid:9606(Homo sapiens mammary carcinoma cells) - 2010/06/28 2021/11/30 rogid:uRLA3ysTgqKQuay0GPRQzdZXnuQ9606 rogid:guTURyt26f1ort4NAlYyabNc+WE9606 intact-crc:58831014F45BE558 false calmodulin binding peptide plus protein a tag:c-c - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)