#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q64663	uniprotkb:B6V8E6	intact:EBI-7037509|ensembl:ENSRNOP00000001746|intact:MINT-3379474	intact:EBI-1549187	psi-mi:p2rx7_rat(display_long)|uniprotkb:P2rx7(gene name)|psi-mi:P2rx7(display_short)|uniprotkb:ATP receptor(gene name synonym)|uniprotkb:Purinergic receptor(gene name synonym)|uniprotkb:P2Z receptor(gene name synonym)	psi-mi:ctnb1_canlf(display_long)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:Beta-catenin(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Bradley et al. (2010)	mint:MINT-8055838|pubmed:21073871|doi:10.1016/j.febslet.2010.11.007|mint:d-10-01235	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8507373|mint:MINT-8055849	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046931"(pore complex assembly)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070230"(positive regulation of lymphocyte apoptotic process)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0098794"(postsynapse)|go:"GO:0099161"(regulation of presynaptic dense core granule exocytosis)|go:"GO:1904172"(positive regulation of bleb assembly)|go:"GO:1904669"(ATP export)|interpro:IPR001429(P2X purinoreceptor)|interpro:IPR003050(P2X7 purinoceptor)|interpro:IPR027309|ensembl:ENSRNOG00000001296(gene)|ensembl:ENSRNOT00000001746(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001614"(purinergic nucleotide receptor activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0004931"(extracellularly ATP-gated cation channel activity)|mint:Q64663|rcsb pdb:6U9V|rcsb pdb:6U9W|reactome:R-RNO-139853|reactome:R-RNO-418346|reactome:R-RNO-844456|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006649"(phospholipid transfer to membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008219"(cell death)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010467"(gene expression)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012501"(programmed cell death)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032059"(bleb)|go:"GO:0032060"(bleb assembly)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0035590"(purinergic nucleotide receptor signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043132"(NAD transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014054"(positive regulation of gamma-aminobutyric acid secretion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015267"(channel activity)|go:"GO:0015695"(organic cation transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016485"(protein processing)|refseq:NP_062129.1|rgd:3241|mint:MINT-8055851(identity)	refseq:NP_001131124.1|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR013284(Beta-catenin)|refseq:XP_013961954.1|refseq:XP_013961955.1|go:"GO:0000922"(spindle pole)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016342"(catenin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042995"(cell projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0045202"(synapse)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1990138"(neuron projection extension)|go:"GO:2000008"(regulation of protein localization to cell surface)|mint:MINT-8055852(identity)	go:"GO:0009925"(basal plasma membrane)	comment:mint|function:Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells	-	figure legend:f1c|comment:mint	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2010/11/05	2014/10/16	rogid:uWBbXowantacie9Fq8DgI/2vRm810116	rogid:29IyntaqY7McjU1KoKWKAJNCt809615	intact-crc:07CB0A10E230DA92|rigid:jRfTqXq+A1TpA0l4VgWnshgS1Tg	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)