#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9UQ84	uniprotkb:Q99708	intact:EBI-944667|uniprotkb:O60545|uniprotkb:O75214|uniprotkb:O75466|uniprotkb:Q5T396|uniprotkb:Q96IJ1|uniprotkb:Q9UG38|uniprotkb:Q9UNW0|ensembl:ENSP00000311873|ensembl:ENSP00000355506	intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3	psi-mi:exo1_human(display_long)|uniprotkb:EXO1(gene name)|psi-mi:EXO1(display_short)|uniprotkb:EXOI(gene name synonym)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Exonuclease I(gene name synonym)	psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eid et al. (2010)	pubmed:21052091|imex:IM-15314|mint:MINT-8081463|doi:10.1038/embor.2010.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496244|mint:MINT-8081471|imex:IM-15314-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003677.4|refseq:NP_006018.4|refseq:NP_569082.2|refseq:XP_006711903.1|refseq:XP_011542623.1|refseq:XP_011542624.1|dip:DIP-36701N|ensembl:ENSG00000174371(gene)|ensembl:ENST00000348581(transcript)|ensembl:ENST00000366548(transcript)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016604"(nuclear body)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051908"(double-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0090656"(t-circle formation)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR032641|interpro:IPR036279|interpro:IPR037315|interpro:IPR044752|rcsb pdb:3QE9|rcsb pdb:3QEA|rcsb pdb:3QEB|rcsb pdb:5UZV|rcsb pdb:5V04|rcsb pdb:5V05|rcsb pdb:5V06|rcsb pdb:5V07|rcsb pdb:5V08|rcsb pdb:5V09|rcsb pdb:5V0A|rcsb pdb:5V0B|rcsb pdb:5V0C|rcsb pdb:5V0D|rcsb pdb:5V0E|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|mint:MINT-8081474(identity)	refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N|mint:MINT-8081473(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f2a sf2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/12/15	2014/10/16	rogid:fvuFXVLS3mhyuaULAvHba1VPw8M9606	rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606	intact-crc:36BD02F81E954A08|rigid:eZTnwwLGeMUjI+FMndrUl2wUYKg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q99708	uniprotkb:Q9UQ84	intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3	intact:EBI-944667|uniprotkb:O60545|uniprotkb:O75214|uniprotkb:O75466|uniprotkb:Q5T396|uniprotkb:Q96IJ1|uniprotkb:Q9UG38|uniprotkb:Q9UNW0|ensembl:ENSP00000311873|ensembl:ENSP00000355506	psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)	psi-mi:exo1_human(display_long)|uniprotkb:EXO1(gene name)|psi-mi:EXO1(display_short)|uniprotkb:EXOI(gene name synonym)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Exonuclease I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eid et al. (2010)	pubmed:21052091|imex:IM-15314|mint:MINT-8081463|doi:10.1038/embor.2010.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496305|mint:MINT-8081490|imex:IM-15314-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N|mint:MINT-8081492(identity)	refseq:NP_003677.4|refseq:NP_006018.4|refseq:NP_569082.2|refseq:XP_006711903.1|refseq:XP_011542623.1|refseq:XP_011542624.1|dip:DIP-36701N|ensembl:ENSG00000174371(gene)|ensembl:ENST00000348581(transcript)|ensembl:ENST00000366548(transcript)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016604"(nuclear body)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051908"(double-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0090656"(t-circle formation)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR032641|interpro:IPR036279|interpro:IPR037315|interpro:IPR044752|rcsb pdb:3QE9|rcsb pdb:3QEA|rcsb pdb:3QEB|rcsb pdb:5UZV|rcsb pdb:5V04|rcsb pdb:5V05|rcsb pdb:5V06|rcsb pdb:5V07|rcsb pdb:5V08|rcsb pdb:5V09|rcsb pdb:5V0A|rcsb pdb:5V0B|rcsb pdb:5V0C|rcsb pdb:5V0D|rcsb pdb:5V0E|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|mint:MINT-8081494(identity)	-	-	-	figure legend:sf2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/12/15	2014/10/16	rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606	rogid:fvuFXVLS3mhyuaULAvHba1VPw8M9606	intact-crc:785A162D45AFC890|rigid:eZTnwwLGeMUjI+FMndrUl2wUYKg	false	-	tag:?-?(MINT-8081499)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P49959	uniprotkb:Q99708	intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863	intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3	psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym)	psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eid et al. (2010)	pubmed:21052091|imex:IM-15314|mint:MINT-8081463|doi:10.1038/embor.2010.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496273|mint:MINT-8081480|imex:IM-15314-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|mint:MINT-8081484(identity)	refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N|mint:MINT-8081482(identity)	-	-	-	figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/12/15	2014/10/16	rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606	rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606	intact-crc:60E64B4BC9984B81|rigid:Sv+HYUiXpUh4zTsivFYkEOAUXa4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9UQ84	uniprotkb:Q99708	intact:EBI-944667|uniprotkb:O60545|uniprotkb:O75214|uniprotkb:O75466|uniprotkb:Q5T396|uniprotkb:Q96IJ1|uniprotkb:Q9UG38|uniprotkb:Q9UNW0|ensembl:ENSP00000311873|ensembl:ENSP00000355506	intact:EBI-745715|uniprotkb:A6NKN2|ensembl:ENSP00000323050|ensembl:ENSP00000382628|intact:EBI-1263531|uniprotkb:A8K8W6|uniprotkb:E7ETY1|uniprotkb:O75371|uniprotkb:Q8NHQ3	psi-mi:exo1_human(display_long)|uniprotkb:EXO1(gene name)|psi-mi:EXO1(display_short)|uniprotkb:EXOI(gene name synonym)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Exonuclease I(gene name synonym)	psi-mi:ctip_human(display_long)|uniprotkb:RBBP8(gene name)|psi-mi:RBBP8(display_short)|uniprotkb:CTIP(gene name synonym)|uniprotkb:CtBP-interacting protein(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 8(gene name synonym)|uniprotkb:Retinoblastoma-interacting protein and myosin-like(gene name synonym)|uniprotkb:Sporulation in the absence of SPO11 protein 2 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Eid et al. (2010)	pubmed:21052091|imex:IM-15314|mint:MINT-8081463|doi:10.1038/embor.2010.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496329|mint:MINT-8081502|imex:IM-15314-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003677.4|refseq:NP_006018.4|refseq:NP_569082.2|refseq:XP_006711903.1|refseq:XP_011542623.1|refseq:XP_011542624.1|dip:DIP-36701N|ensembl:ENSG00000174371(gene)|ensembl:ENST00000348581(transcript)|ensembl:ENST00000366548(transcript)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016604"(nuclear body)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051908"(double-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0090656"(t-circle formation)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR032641|interpro:IPR036279|interpro:IPR037315|interpro:IPR044752|rcsb pdb:3QE9|rcsb pdb:3QEA|rcsb pdb:3QEB|rcsb pdb:5UZV|rcsb pdb:5V04|rcsb pdb:5V05|rcsb pdb:5V06|rcsb pdb:5V07|rcsb pdb:5V08|rcsb pdb:5V09|rcsb pdb:5V0A|rcsb pdb:5V0B|rcsb pdb:5V0C|rcsb pdb:5V0D|rcsb pdb:5V0E|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|mint:MINT-8081506(identity)	refseq:XP_011524434.1|ensembl:ENSG00000101773(gene)|ensembl:ENST00000327155(transcript)|ensembl:ENST00000399722(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010792"(DNA double-strand break processing involved in repair via single-strand annealing)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070336"(flap-structured DNA binding)|interpro:IPR013882(DNA repair protein Sae2)|interpro:IPR019518|interpro:IPR033316|interpro:IPR033594|mint:Q99708|rcsb pdb:2L4Z|rcsb pdb:4D2H|rcsb pdb:7BGF|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|refseq:NP_002885.1|refseq:NP_976036.1|refseq:NP_976037.1|refseq:XP_006722582.1|refseq:XP_006722583.1|refseq:XP_006722584.1|dip:DIP-24244N|mint:MINT-8081504(identity)	-	-	-	figure legend:f2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/12/15	2014/10/16	rogid:fvuFXVLS3mhyuaULAvHba1VPw8M9606	rogid:4oYHOQGiavaE9TTzRbHyOZtL28E9606	intact-crc:0BAAFD366B49C76D|rigid:eZTnwwLGeMUjI+FMndrUl2wUYKg	false	-	flag tag:?-?(MINT-8081513)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9UQ84	uniprotkb:P16104	intact:EBI-944667|uniprotkb:O60545|uniprotkb:O75214|uniprotkb:O75466|uniprotkb:Q5T396|uniprotkb:Q96IJ1|uniprotkb:Q9UG38|uniprotkb:Q9UNW0|ensembl:ENSP00000311873|ensembl:ENSP00000355506	intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024	psi-mi:exo1_human(display_long)|uniprotkb:EXO1(gene name)|psi-mi:EXO1(display_short)|uniprotkb:EXOI(gene name synonym)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Exonuclease I(gene name synonym)	psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Eid et al. (2010)	pubmed:21052091|imex:IM-15314|mint:MINT-8081463|doi:10.1038/embor.2010.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496409|mint:MINT-8081518|imex:IM-15314-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003677.4|refseq:NP_006018.4|refseq:NP_569082.2|refseq:XP_006711903.1|refseq:XP_011542623.1|refseq:XP_011542624.1|dip:DIP-36701N|ensembl:ENSG00000174371(gene)|ensembl:ENST00000348581(transcript)|ensembl:ENST00000366548(transcript)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016604"(nuclear body)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051908"(double-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0090656"(t-circle formation)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR032641|interpro:IPR036279|interpro:IPR037315|interpro:IPR044752|rcsb pdb:3QE9|rcsb pdb:3QEA|rcsb pdb:3QEB|rcsb pdb:5UZV|rcsb pdb:5V04|rcsb pdb:5V05|rcsb pdb:5V06|rcsb pdb:5V07|rcsb pdb:5V08|rcsb pdb:5V09|rcsb pdb:5V0A|rcsb pdb:5V0B|rcsb pdb:5V0C|rcsb pdb:5V0D|rcsb pdb:5V0E|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|mint:MINT-8081524(identity)	ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|mint:MINT-8081533(identity)	go:"GO:0000729"(DNA double-strand break processing)	-	-	figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2010/12/15	2014/10/16	rogid:fvuFXVLS3mhyuaULAvHba1VPw8M9606	rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606	intact-crc:31876376D9E1A5BB|rigid:b1CvprT9OnQ3Rarx/grxgHQMTmo	false	green fluorescent protein tag:?-?(MINT-8081529)	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q9UQ84	uniprotkb:P15927	intact:EBI-944667|uniprotkb:O60545|uniprotkb:O75214|uniprotkb:O75466|uniprotkb:Q5T396|uniprotkb:Q96IJ1|uniprotkb:Q9UG38|uniprotkb:Q9UNW0|ensembl:ENSP00000311873|ensembl:ENSP00000355506	intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5	psi-mi:exo1_human(display_long)|uniprotkb:EXO1(gene name)|psi-mi:EXO1(display_short)|uniprotkb:EXOI(gene name synonym)|uniprotkb:HEX1(gene name synonym)|uniprotkb:Exonuclease I(gene name synonym)	psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Eid et al. (2010)	pubmed:21052091|imex:IM-15314|mint:MINT-8081463|doi:10.1038/embor.2010.157	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8496409|mint:MINT-8081518|imex:IM-15314-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003677.4|refseq:NP_006018.4|refseq:NP_569082.2|refseq:XP_006711903.1|refseq:XP_011542623.1|refseq:XP_011542624.1|dip:DIP-36701N|ensembl:ENSG00000174371(gene)|ensembl:ENST00000348581(transcript)|ensembl:ENST00000366548(transcript)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016604"(nuclear body)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0045145"(single-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0045190"(isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051908"(double-stranded DNA 5'-3' exodeoxyribonuclease activity)|go:"GO:0090656"(t-circle formation)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR029060|interpro:IPR032641|interpro:IPR036279|interpro:IPR037315|interpro:IPR044752|rcsb pdb:3QE9|rcsb pdb:3QEA|rcsb pdb:3QEB|rcsb pdb:5UZV|rcsb pdb:5V04|rcsb pdb:5V05|rcsb pdb:5V06|rcsb pdb:5V07|rcsb pdb:5V08|rcsb pdb:5V09|rcsb pdb:5V0A|rcsb pdb:5V0B|rcsb pdb:5V0C|rcsb pdb:5V0D|rcsb pdb:5V0E|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|mint:MINT-8081524(identity)	rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N|mint:MINT-8081520(identity)	go:"GO:0000729"(DNA double-strand break processing)	-	-	figure legend:f1a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2010/12/15	2014/10/16	rogid:fvuFXVLS3mhyuaULAvHba1VPw8M9606	rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606	intact-crc:31876376D9E1A5BB|rigid:b1CvprT9OnQ3Rarx/grxgHQMTmo	false	green fluorescent protein tag:?-?(MINT-8081529)	-	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0422"(immunostaining)