#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P00736 uniprotkb:P00736 intact:EBI-3926504|uniprotkb:Q8J012|uniprotkb:Q68D77|uniprotkb:A6NJQ8 intact:EBI-3926504|uniprotkb:Q8J012|uniprotkb:Q68D77|uniprotkb:A6NJQ8 psi-mi:c1r_human(display_long)|uniprotkb:C1R(gene name)|psi-mi:C1R(display_short)|uniprotkb:Complement component 1 subcomponent r(gene name synonym) psi-mi:c1r_human(display_long)|uniprotkb:C1R(gene name)|psi-mi:C1R(display_short)|uniprotkb:Complement component 1 subcomponent r(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Láng et al. (2010) pubmed:20970424|imex:IM-15659|mint:MINT-8045727|doi:10.1016/j.febslet.2010.10.033 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-8479962|mint:MINT-8045767|imex:IM-15659-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR035914|interpro:IPR035976|rcsb pdb:6F1C|rcsb pdb:6F1D|rcsb pdb:6F1H|refseq:NP_001724.3|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR000436(Sushi/SCR/CCP)|rcsb pdb:1APQ|rcsb pdb:1GPZ|rcsb pdb:1MD7|rcsb pdb:1MD8|rcsb pdb:2QY0|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0031638"(zymogen activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR033116|rcsb pdb:6F39|interpro:IPR000742(EGF-like, type 3)|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|interpro:IPR035707|interpro:IPR043504|mint:MINT-8045770(identity) interpro:IPR035914|interpro:IPR035976|rcsb pdb:6F1C|rcsb pdb:6F1D|rcsb pdb:6F1H|refseq:NP_001724.3|interpro:IPR000859(CUB)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR018097|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR000436(Sushi/SCR/CCP)|rcsb pdb:1APQ|rcsb pdb:1GPZ|rcsb pdb:1MD7|rcsb pdb:1MD8|rcsb pdb:2QY0|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0031638"(zymogen activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR033116|rcsb pdb:6F39|interpro:IPR000742(EGF-like, type 3)|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-977606|interpro:IPR035707|interpro:IPR043504|mint:MINT-8045769(identity) - - - comment:homomint|comment:mint|figure legend:F1 f2 f4b fs2 ts1 ts2 ts3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/10/14 2014/10/16 rogid:7E+ASC6Hv3CoXdwfWEMwCtYALbw9606 rogid:7E+ASC6Hv3CoXdwfWEMwCtYALbw9606 intact-crc:5CF1CA6CABE829B7|rigid:XUBfWIA3qDT70BGNoLrmJX4GWe8 false binding-associated region:373-450(MINT-8045784) binding-associated region:190-375(MINT-8045780) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)