#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O94830 uniprotkb:P53618 intact:EBI-8444979|uniprotkb:B3KXB5|intact:MINT-4649256|intact:MINT-4940977|uniprotkb:B3KWV2|uniprotkb:Q9H8X7|ensembl:ENSP00000380352|ensembl:ENSP00000429932 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 psi-mi:ddhd2_human(display_long)|uniprotkb:DDHD2(gene name)|psi-mi:DDHD2(display_short)|uniprotkb:KIAA0725(gene name synonym)|uniprotkb:KIAA0725p(gene name synonym)|uniprotkb:SAMWD1(gene name synonym)|uniprotkb:DDHD domain-containing protein 2(gene name synonym)|uniprotkb:SAM, WWE and DDHD domain-containing protein 1(gene name synonym) psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Sato et al. (2010) pubmed:20932832|imex:IM-15849|mint:MINT-8019760|doi:10.1016/j.febslet.2010.09.047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8444972|mint:MINT-8019765|imex:IM-15849-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011542758.1|refseq:NP_001157704.1|refseq:NP_056029.2|refseq:XP_005273511.1|refseq:XP_005273512.1|refseq:XP_016868741.1|refseq:XP_016868742.1|refseq:XP_016868743.1|refseq:XP_016868744.1|refseq:XP_016868745.1|ensembl:ENSG00000085788(gene)|ensembl:ENST00000397166(transcript)|ensembl:ENST00000520272(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0046872"(metal ion binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004170(WWE)|interpro:IPR004177(DDHD)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-HSA-1483166|mint:MINT-8019767(identity) refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N|mint:MINT-8019768(identity) go:"GO:0005794"(Golgi apparatus) comment:mint|function:Phospholipase that hydrolyzes preferentially phosphatidic acid and phosphatidylethanolamine. May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures - figure legend:f1a f1b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/09/28 2014/10/16 rogid:3Tw/oOkOaBJqJ0jyUBrsYy1ASyM9606 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 intact-crc:13BBCD5274BDB363|rigid:VGeUblfaXlguelEeCH5UAtQRMUA false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:O94830 uniprotkb:Q5PXD5 intact:EBI-8444979|uniprotkb:B3KXB5|intact:MINT-4649256|intact:MINT-4940977|uniprotkb:B3KWV2|uniprotkb:Q9H8X7|ensembl:ENSP00000380352|ensembl:ENSP00000429932 intact:EBI-8445042|intact:MINT-4886542 psi-mi:ddhd2_human(display_long)|uniprotkb:DDHD2(gene name)|psi-mi:DDHD2(display_short)|uniprotkb:KIAA0725(gene name synonym)|uniprotkb:KIAA0725p(gene name synonym)|uniprotkb:SAMWD1(gene name synonym)|uniprotkb:DDHD domain-containing protein 2(gene name synonym)|uniprotkb:SAM, WWE and DDHD domain-containing protein 1(gene name synonym) psi-mi:q5pxd5_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Sato et al. (2010) pubmed:20932832|imex:IM-15849|mint:MINT-8019760|doi:10.1016/j.febslet.2010.09.047 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8445035|mint:MINT-8019775|imex:IM-15849-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011542758.1|refseq:NP_001157704.1|refseq:NP_056029.2|refseq:XP_005273511.1|refseq:XP_005273512.1|refseq:XP_016868741.1|refseq:XP_016868742.1|refseq:XP_016868743.1|refseq:XP_016868744.1|refseq:XP_016868745.1|ensembl:ENSG00000085788(gene)|ensembl:ENST00000397166(transcript)|ensembl:ENST00000520272(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0046872"(metal ion binding)|go:"GO:0090141"(positive regulation of mitochondrial fission)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004170(WWE)|interpro:IPR004177(DDHD)|interpro:IPR013761(Sterile alpha motif-type)|reactome:R-HSA-1483166|mint:MINT-8019778(identity) interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|mint:MINT-8019780(identity) go:"GO:0005794"(Golgi apparatus) comment:mint|function:Phospholipase that hydrolyzes preferentially phosphatidic acid and phosphatidylethanolamine. May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures comment:"fragmentation type: fragment"|comment:mint figure legend:f1c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/09/28 2014/10/16 rogid:3Tw/oOkOaBJqJ0jyUBrsYy1ASyM9606 rogid:ZX66gY0v4rYX7PuIe6D5vqqlmoI9606 intact-crc:51786E6E1119FF1C|rigid:78IBDndPkqFL7COLoIcOgZCgx7M false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)