#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P9WI75	uniprotkb:P9WPE7	intact:EBI-2945875|uniprotkb:L0T7T0|uniprotkb:O08151|uniprotkb:P72003	intact:EBI-2945826|uniprotkb:L0T3Q6|uniprotkb:P06806|uniprotkb:Q48920|uniprotkb:Q48931|uniprotkb:P0A520	psi-mi:pknf_myctu(display_long)|uniprotkb:pknF(gene name)|psi-mi:pknF(display_short)|uniprotkb:MTCY28.09(orf name)|uniprotkb:Rv1746(locus name)	psi-mi:ch602_myctu(display_long)|uniprotkb:groEL2(gene name)|psi-mi:groEL2(display_short)|uniprotkb:65 kDa antigen(gene name synonym)|uniprotkb:Antigen A(gene name synonym)|uniprotkb:Cell wall protein A(gene name synonym)|uniprotkb:Heat shock protein 65(gene name synonym)|uniprotkb:groL2(gene name synonym)|uniprotkb:hsp65(gene name synonym)|uniprotkb:60 kDa chaperonin 2(gene name synonym)|uniprotkb:Chaperonin-60 2(gene name synonym)|uniprotkb:cpn60.2(gene name synonym)|uniprotkb:mtc28(orf name)|uniprotkb:Rv0440(locus name)|uniprotkb:MTV037.04(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2945870|imex:IM-15201-1	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000921"(septin ring assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_216262.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003899000.1	go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042603"(capsule)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990220"(GroEL-GroES complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_214954.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|rcsb pdb:1SJP|rcsb pdb:3RTK|refseq:WP_003402236.1|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:"Eight distinct phosphorylated residues (on GroEL2)were identified."|figure legend:"Fig 2B, (Fig S1)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2010/11/25	2014/10/16	rogid:C97FRlJERgQL0geXkkP9hwJEwCk83332	rogid:C6siOCo/hWBtmYmu77f2SDtnAaU83332	intact-crc:2C7CA2DFA2FA8FA7|rigid:IbwwENUb0oq4eDFqCh8+Q22Swlo	false	sufficient binding region:12..12-279..279(IPR000719)	his tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P9WMK1	uniprotkb:P9WI75	intact:EBI-2945921|uniprotkb:L0TBA7|uniprotkb:P30223|uniprotkb:P0A5B7	intact:EBI-2945875|uniprotkb:L0T7T0|uniprotkb:O08151|uniprotkb:P72003	psi-mi:acr_myctu(display_long)|uniprotkb:hspX(gene name)|psi-mi:hspX(display_short)|uniprotkb:acr(gene name synonym)|uniprotkb:14 kDa antigen(gene name synonym)|uniprotkb:16 kDa antigen(gene name synonym)|uniprotkb:HSP 16.3(gene name synonym)|uniprotkb:Nox16(gene name synonym)|uniprotkb:MTV018.18c(orf name)|uniprotkb:Rv2031c(locus name)	psi-mi:pknf_myctu(display_long)|uniprotkb:pknF(gene name)|psi-mi:pknF(display_short)|uniprotkb:MTCY28.09(orf name)|uniprotkb:Rv1746(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2945909|imex:IM-15201-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0010039"(response to iron ion)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0052572"(response to host immune response)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0075136"(response to host)|go:"GO:0001666"(response to hypoxia)|refseq:NP_216547.1|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_003410189.1|interpro:IPR031107	go:"GO:0000921"(septin ring assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_216262.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003899000.1	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Four distinct phosphorylation sites on HspX were identified.|figure legend:"Fig 3B, (Fig S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	-	2010/11/25	2014/10/16	rogid:zABUvnZ/UUuhnsNaCM5nJCxYsHY83332	rogid:C97FRlJERgQL0geXkkP9hwJEwCk83332	intact-crc:8B34A05B75C518CB|rigid:nTLPAp5WxAwp9Pd2F32bDfU9OFI	false	-	sufficient binding region:12..12-279..279(IPR000719)|his tag:n-n	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P9WI75	uniprotkb:P9WPE7	intact:EBI-2945875|uniprotkb:L0T7T0|uniprotkb:O08151|uniprotkb:P72003	intact:EBI-2945826|uniprotkb:L0T3Q6|uniprotkb:P06806|uniprotkb:Q48920|uniprotkb:Q48931|uniprotkb:P0A520	psi-mi:pknf_myctu(display_long)|uniprotkb:pknF(gene name)|psi-mi:pknF(display_short)|uniprotkb:MTCY28.09(orf name)|uniprotkb:Rv1746(locus name)	psi-mi:ch602_myctu(display_long)|uniprotkb:groEL2(gene name)|psi-mi:groEL2(display_short)|uniprotkb:65 kDa antigen(gene name synonym)|uniprotkb:Antigen A(gene name synonym)|uniprotkb:Cell wall protein A(gene name synonym)|uniprotkb:Heat shock protein 65(gene name synonym)|uniprotkb:groL2(gene name synonym)|uniprotkb:hsp65(gene name synonym)|uniprotkb:60 kDa chaperonin 2(gene name synonym)|uniprotkb:Chaperonin-60 2(gene name synonym)|uniprotkb:cpn60.2(gene name synonym)|uniprotkb:mtc28(orf name)|uniprotkb:Rv0440(locus name)|uniprotkb:MTV037.04(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2945964|imex:IM-15201-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000921"(septin ring assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_216262.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003899000.1	go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042603"(capsule)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990220"(GroEL-GroES complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_214954.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|rcsb pdb:1SJP|rcsb pdb:3RTK|refseq:WP_003402236.1|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:"Three distinct phosphorylated residues (on GroEL2)were identified.  Single mutants revealed different levels of phosphorylation and phosphorylation of the triple mutant was completely abrogated with respect to GroEL2_WT."|figure legend:Fig 2A, 2C- lower panel.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:C97FRlJERgQL0geXkkP9hwJEwCk83332	rogid:C6siOCo/hWBtmYmu77f2SDtnAaU83332	intact-crc:24044EC54072C4B9|rigid:IbwwENUb0oq4eDFqCh8+Q22Swlo	false	his tag:?-?(IPR000719)|sufficient binding region:12..12-279..279	his tag:n-n|tag:?-?|mutation decreasing interaction:127-127|mutation decreasing interaction:90-90|mutation decreasing interaction:92-92	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WI83	uniprotkb:P9WPE7	intact:EBI-2946007|uniprotkb:L0T594|uniprotkb:P71585|uniprotkb:P65726	intact:EBI-2945826|uniprotkb:L0T3Q6|uniprotkb:P06806|uniprotkb:Q48920|uniprotkb:Q48931|uniprotkb:P0A520	psi-mi:pkna_myctu(display_long)|uniprotkb:pknA(gene name)|psi-mi:pknA(display_short)|uniprotkb:MTCY10H4.15c(orf name)|uniprotkb:Rv0015c(locus name)	psi-mi:ch602_myctu(display_long)|uniprotkb:groEL2(gene name)|psi-mi:groEL2(display_short)|uniprotkb:65 kDa antigen(gene name synonym)|uniprotkb:Antigen A(gene name synonym)|uniprotkb:Cell wall protein A(gene name synonym)|uniprotkb:Heat shock protein 65(gene name synonym)|uniprotkb:groL2(gene name synonym)|uniprotkb:hsp65(gene name synonym)|uniprotkb:60 kDa chaperonin 2(gene name synonym)|uniprotkb:Chaperonin-60 2(gene name synonym)|uniprotkb:cpn60.2(gene name synonym)|uniprotkb:mtc28(orf name)|uniprotkb:Rv0440(locus name)|uniprotkb:MTV037.04(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2945987|imex:IM-15201-9	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_214529.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:4OW8|rcsb pdb:4X3F|refseq:WP_003400358.1|rcsb pdb:6B2Q	go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042603"(capsule)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990220"(GroEL-GroES complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_214954.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|rcsb pdb:1SJP|rcsb pdb:3RTK|refseq:WP_003402236.1|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:Phosphorylation of GroEL2.|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:/XIFxUC7d2yokj0Bf2Z5TL7AvYw83332	rogid:C6siOCo/hWBtmYmu77f2SDtnAaU83332	intact-crc:BA15DBF44B4F211D|rigid:YvYvsJQ07gQZPPIsKcpAUV+oEes	false	his tag:?-?	his tag:n-n|tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WPE7	uniprotkb:P9WI81	intact:EBI-2945826|uniprotkb:L0T3Q6|uniprotkb:P06806|uniprotkb:Q48920|uniprotkb:Q48931|uniprotkb:P0A520	intact:EBI-2946037|uniprotkb:L0T5F6|uniprotkb:P71584|uniprotkb:P0A5S4	psi-mi:ch602_myctu(display_long)|uniprotkb:groEL2(gene name)|psi-mi:groEL2(display_short)|uniprotkb:65 kDa antigen(gene name synonym)|uniprotkb:Antigen A(gene name synonym)|uniprotkb:Cell wall protein A(gene name synonym)|uniprotkb:Heat shock protein 65(gene name synonym)|uniprotkb:groL2(gene name synonym)|uniprotkb:hsp65(gene name synonym)|uniprotkb:60 kDa chaperonin 2(gene name synonym)|uniprotkb:Chaperonin-60 2(gene name synonym)|uniprotkb:cpn60.2(gene name synonym)|uniprotkb:mtc28(orf name)|uniprotkb:Rv0440(locus name)|uniprotkb:MTV037.04(orf name)	psi-mi:pknb_myctu(display_long)|uniprotkb:pknB(gene name)|psi-mi:pknB(display_short)|uniprotkb:MTCY10H4.14c(orf name)|uniprotkb:Rv0014c(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946077|imex:IM-15201-10	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042603"(capsule)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990220"(GroEL-GroES complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_214954.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|rcsb pdb:1SJP|rcsb pdb:3RTK|refseq:WP_003402236.1|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0052572"(response to host immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:1MRU|rcsb pdb:1O6Y|rcsb pdb:2FUM|rcsb pdb:2KUD|rcsb pdb:2KUE|rcsb pdb:2KUF|rcsb pdb:2KUI|rcsb pdb:3F61|rcsb pdb:3F69|rcsb pdb:3ORI|rcsb pdb:3ORO|rcsb pdb:5E0Y|rcsb pdb:5E0Z|rcsb pdb:5E10|rcsb pdb:5U94|rcsb pdb:6B2P|rcsb pdb:6I2P|rcsb pdb:5E12|refseq:NP_214528.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR005543(PASTA)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003400356.1|mint:P9WI81	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	crc64:6C27EEBE9D5A453B	resulting-ptm:Phosphorylation of GroEL2.|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:C6siOCo/hWBtmYmu77f2SDtnAaU83332	rogid:KZ9ghc/5dguERQl5GY7dMe8Zc2I83332	intact-crc:3396963D10C0A575|rigid:PB25O5vu6Hb3W2UnPybHq5NWCJE	false	tag:?-?|his tag:n-n	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WPE7	uniprotkb:P9WI79	intact:EBI-2945826|uniprotkb:L0T3Q6|uniprotkb:P06806|uniprotkb:Q48920|uniprotkb:Q48931|uniprotkb:P0A520	intact:EBI-2946090|uniprotkb:L0T6U6|uniprotkb:P95308|uniprotkb:O05871	psi-mi:ch602_myctu(display_long)|uniprotkb:groEL2(gene name)|psi-mi:groEL2(display_short)|uniprotkb:65 kDa antigen(gene name synonym)|uniprotkb:Antigen A(gene name synonym)|uniprotkb:Cell wall protein A(gene name synonym)|uniprotkb:Heat shock protein 65(gene name synonym)|uniprotkb:groL2(gene name synonym)|uniprotkb:hsp65(gene name synonym)|uniprotkb:60 kDa chaperonin 2(gene name synonym)|uniprotkb:Chaperonin-60 2(gene name synonym)|uniprotkb:cpn60.2(gene name synonym)|uniprotkb:mtc28(orf name)|uniprotkb:Rv0440(locus name)|uniprotkb:MTV037.04(orf name)	psi-mi:pknd_myctu(display_long)|uniprotkb:pknD(gene name)|psi-mi:pknD(display_short)|uniprotkb:MTCY08C9.08(orf name)|uniprotkb:Rv0931c(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946121|imex:IM-15201-6	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042603"(capsule)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990220"(GroEL-GroES complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_214954.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|rcsb pdb:1SJP|rcsb pdb:3RTK|refseq:WP_003402236.1|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_215446.1|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:1RWI|rcsb pdb:1RWL|refseq:WP_003404782.1|interpro:IPR013658(SMP-30/Gluconolaconase/LRE-like region)|interpro:IPR035016	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:Phosphorylation of GroEL2.|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:C6siOCo/hWBtmYmu77f2SDtnAaU83332	rogid:aSLaMNmg7I5BBkHoHAG3rig5GG083332	intact-crc:F5A2D0712429ECEA|rigid:H6W3zHCPlWX4no4xTlNrdTwiiUI	false	tag:?-?|his tag:n-n	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WI77	uniprotkb:P9WPE7	intact:EBI-2946134|uniprotkb:L0TA94|uniprotkb:O08149|uniprotkb:P72001	intact:EBI-2945826|uniprotkb:L0T3Q6|uniprotkb:P06806|uniprotkb:Q48920|uniprotkb:Q48931|uniprotkb:P0A520	psi-mi:pkne_myctu(display_long)|uniprotkb:pknE(gene name)|psi-mi:pknE(display_short)|uniprotkb:MTCY28.05(orf name)|uniprotkb:Rv1743(locus name)	psi-mi:ch602_myctu(display_long)|uniprotkb:groEL2(gene name)|psi-mi:groEL2(display_short)|uniprotkb:65 kDa antigen(gene name synonym)|uniprotkb:Antigen A(gene name synonym)|uniprotkb:Cell wall protein A(gene name synonym)|uniprotkb:Heat shock protein 65(gene name synonym)|uniprotkb:groL2(gene name synonym)|uniprotkb:hsp65(gene name synonym)|uniprotkb:60 kDa chaperonin 2(gene name synonym)|uniprotkb:Chaperonin-60 2(gene name synonym)|uniprotkb:cpn60.2(gene name synonym)|uniprotkb:mtc28(orf name)|uniprotkb:Rv0440(locus name)|uniprotkb:MTV037.04(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946160|imex:IM-15201-7	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_216259.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR012336(Thioredoxin-like fold)|rcsb pdb:2H34|refseq:WP_003898998.1|interpro:IPR036249	go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042603"(capsule)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990220"(GroEL-GroES complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_214954.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|rcsb pdb:1SJP|rcsb pdb:3RTK|refseq:WP_003402236.1|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Phosphorylation of GroEL2.|figure legend:Fig 2A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:BXyKZFftcyK/SjExy+wU1gswM3s83332	rogid:C6siOCo/hWBtmYmu77f2SDtnAaU83332	intact-crc:CF0CC29EB60E312E|rigid:kRr2bYQ8fZzIIZg55CZZFhbnsT4	false	his tag:?-?	tag:?-?|his tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WMK1	uniprotkb:P9WI75	intact:EBI-2945921|uniprotkb:L0TBA7|uniprotkb:P30223|uniprotkb:P0A5B7	intact:EBI-2945875|uniprotkb:L0T7T0|uniprotkb:O08151|uniprotkb:P72003	psi-mi:acr_myctu(display_long)|uniprotkb:hspX(gene name)|psi-mi:hspX(display_short)|uniprotkb:acr(gene name synonym)|uniprotkb:14 kDa antigen(gene name synonym)|uniprotkb:16 kDa antigen(gene name synonym)|uniprotkb:HSP 16.3(gene name synonym)|uniprotkb:Nox16(gene name synonym)|uniprotkb:MTV018.18c(orf name)|uniprotkb:Rv2031c(locus name)	psi-mi:pknf_myctu(display_long)|uniprotkb:pknF(gene name)|psi-mi:pknF(display_short)|uniprotkb:MTCY28.09(orf name)|uniprotkb:Rv1746(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946271|imex:IM-15201-4	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0010039"(response to iron ion)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0052572"(response to host immune response)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0075136"(response to host)|go:"GO:0001666"(response to hypoxia)|refseq:NP_216547.1|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_003410189.1|interpro:IPR031107	go:"GO:0000921"(septin ring assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_216262.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003899000.1	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:Phosphorylation of HspX.|figure legend:"Fig 3A, 3B (bottom panel)"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:zABUvnZ/UUuhnsNaCM5nJCxYsHY83332	rogid:C97FRlJERgQL0geXkkP9hwJEwCk83332	intact-crc:55D6F453EA465622|rigid:nTLPAp5WxAwp9Pd2F32bDfU9OFI	false	his tag:n-n|tag:?-?|mutation decreasing interaction:4-4|mutation decreasing interaction:19-19|mutation decreasing interaction:27-27|mutation decreasing interaction:134-134	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WI83	uniprotkb:P9WMK1	intact:EBI-2946007|uniprotkb:L0T594|uniprotkb:P71585|uniprotkb:P65726	intact:EBI-2945921|uniprotkb:L0TBA7|uniprotkb:P30223|uniprotkb:P0A5B7	psi-mi:pkna_myctu(display_long)|uniprotkb:pknA(gene name)|psi-mi:pknA(display_short)|uniprotkb:MTCY10H4.15c(orf name)|uniprotkb:Rv0015c(locus name)	psi-mi:acr_myctu(display_long)|uniprotkb:hspX(gene name)|psi-mi:hspX(display_short)|uniprotkb:acr(gene name synonym)|uniprotkb:14 kDa antigen(gene name synonym)|uniprotkb:16 kDa antigen(gene name synonym)|uniprotkb:HSP 16.3(gene name synonym)|uniprotkb:Nox16(gene name synonym)|uniprotkb:MTV018.18c(orf name)|uniprotkb:Rv2031c(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946288|imex:IM-15201-5	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_214529.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:4OW8|rcsb pdb:4X3F|refseq:WP_003400358.1|rcsb pdb:6B2Q	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0010039"(response to iron ion)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0052572"(response to host immune response)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0075136"(response to host)|go:"GO:0001666"(response to hypoxia)|refseq:NP_216547.1|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_003410189.1|interpro:IPR031107	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Phosphorylation of HspX.|figure legend:Fig 3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:/XIFxUC7d2yokj0Bf2Z5TL7AvYw83332	rogid:zABUvnZ/UUuhnsNaCM5nJCxYsHY83332	intact-crc:D9871FB923ABCB02|rigid:m//GKkpDpeMFszNLexicAj6jDww	false	glutathione s tranferase tag:?-?	his tag:n-n|tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WMK1	uniprotkb:P9WI81	intact:EBI-2945921|uniprotkb:L0TBA7|uniprotkb:P30223|uniprotkb:P0A5B7	intact:EBI-2946037|uniprotkb:L0T5F6|uniprotkb:P71584|uniprotkb:P0A5S4	psi-mi:acr_myctu(display_long)|uniprotkb:hspX(gene name)|psi-mi:hspX(display_short)|uniprotkb:acr(gene name synonym)|uniprotkb:14 kDa antigen(gene name synonym)|uniprotkb:16 kDa antigen(gene name synonym)|uniprotkb:HSP 16.3(gene name synonym)|uniprotkb:Nox16(gene name synonym)|uniprotkb:MTV018.18c(orf name)|uniprotkb:Rv2031c(locus name)	psi-mi:pknb_myctu(display_long)|uniprotkb:pknB(gene name)|psi-mi:pknB(display_short)|uniprotkb:MTCY10H4.14c(orf name)|uniprotkb:Rv0014c(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946310|imex:IM-15201-8	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0010039"(response to iron ion)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0052572"(response to host immune response)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0075136"(response to host)|go:"GO:0001666"(response to hypoxia)|refseq:NP_216547.1|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_003410189.1|interpro:IPR031107	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009252"(peptidoglycan biosynthetic process)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0052572"(response to host immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|rcsb pdb:1MRU|rcsb pdb:1O6Y|rcsb pdb:2FUM|rcsb pdb:2KUD|rcsb pdb:2KUE|rcsb pdb:2KUF|rcsb pdb:2KUI|rcsb pdb:3F61|rcsb pdb:3F69|rcsb pdb:3ORI|rcsb pdb:3ORO|rcsb pdb:5E0Y|rcsb pdb:5E0Z|rcsb pdb:5E10|rcsb pdb:5U94|rcsb pdb:6B2P|rcsb pdb:6I2P|rcsb pdb:5E12|refseq:NP_214528.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR005543(PASTA)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003400356.1|mint:P9WI81	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	crc64:6C27EEBE9D5A453B	resulting-ptm:Phosphorylation of HspX.|figure legend:Fig 3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:zABUvnZ/UUuhnsNaCM5nJCxYsHY83332	rogid:KZ9ghc/5dguERQl5GY7dMe8Zc2I83332	intact-crc:944E4436A7C32792|rigid:fEaiTDAKVPnk7Dk3XIG+Oy8WYEY	false	his tag:n-n|tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WI79	uniprotkb:P9WMK1	intact:EBI-2946090|uniprotkb:L0T6U6|uniprotkb:P95308|uniprotkb:O05871	intact:EBI-2945921|uniprotkb:L0TBA7|uniprotkb:P30223|uniprotkb:P0A5B7	psi-mi:pknd_myctu(display_long)|uniprotkb:pknD(gene name)|psi-mi:pknD(display_short)|uniprotkb:MTCY08C9.08(orf name)|uniprotkb:Rv0931c(locus name)	psi-mi:acr_myctu(display_long)|uniprotkb:hspX(gene name)|psi-mi:hspX(display_short)|uniprotkb:acr(gene name synonym)|uniprotkb:14 kDa antigen(gene name synonym)|uniprotkb:16 kDa antigen(gene name synonym)|uniprotkb:HSP 16.3(gene name synonym)|uniprotkb:Nox16(gene name synonym)|uniprotkb:MTV018.18c(orf name)|uniprotkb:Rv2031c(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946323|imex:IM-15201-11	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_215446.1|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR001258(NHL repeat)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:1RWI|rcsb pdb:1RWL|refseq:WP_003404782.1|interpro:IPR013658(SMP-30/Gluconolaconase/LRE-like region)|interpro:IPR035016	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0010039"(response to iron ion)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0052572"(response to host immune response)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0075136"(response to host)|go:"GO:0001666"(response to hypoxia)|refseq:NP_216547.1|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_003410189.1|interpro:IPR031107	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Phosphorylation of HspX.|figure legend:Fig 3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:aSLaMNmg7I5BBkHoHAG3rig5GG083332	rogid:zABUvnZ/UUuhnsNaCM5nJCxYsHY83332	intact-crc:7BE4CBEB13B93CFE|rigid:1oToO4P54Ijf9sEkt3Eisg9Kxj4	false	glutathione s tranferase tag:?-?	his tag:n-n|tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WMK1	uniprotkb:P9WI77	intact:EBI-2945921|uniprotkb:L0TBA7|uniprotkb:P30223|uniprotkb:P0A5B7	intact:EBI-2946134|uniprotkb:L0TA94|uniprotkb:O08149|uniprotkb:P72001	psi-mi:acr_myctu(display_long)|uniprotkb:hspX(gene name)|psi-mi:hspX(display_short)|uniprotkb:acr(gene name synonym)|uniprotkb:14 kDa antigen(gene name synonym)|uniprotkb:16 kDa antigen(gene name synonym)|uniprotkb:HSP 16.3(gene name synonym)|uniprotkb:Nox16(gene name synonym)|uniprotkb:MTV018.18c(orf name)|uniprotkb:Rv2031c(locus name)	psi-mi:pkne_myctu(display_long)|uniprotkb:pknE(gene name)|psi-mi:pknE(display_short)|uniprotkb:MTCY28.05(orf name)|uniprotkb:Rv1743(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946336|imex:IM-15201-12	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0010039"(response to iron ion)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0052572"(response to host immune response)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0075136"(response to host)|go:"GO:0001666"(response to hypoxia)|refseq:NP_216547.1|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_003410189.1|interpro:IPR031107	go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_216259.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR012336(Thioredoxin-like fold)|rcsb pdb:2H34|refseq:WP_003898998.1|interpro:IPR036249	go:"GO:0006468"(protein phosphorylation)|go:"GO:0004672"(protein kinase activity)	-	-	resulting-ptm:Phosphorylation of HspX.|figure legend:Fig 3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:zABUvnZ/UUuhnsNaCM5nJCxYsHY83332	rogid:BXyKZFftcyK/SjExy+wU1gswM3s83332	intact-crc:30EDE2F83398989F|rigid:rOG17Dx3+v0LRmw5M+7TaWLrwi4	false	his tag:n-n|tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WMK1	uniprotkb:P9WI71	intact:EBI-2945921|uniprotkb:L0TBA7|uniprotkb:P30223|uniprotkb:P0A5B7	intact:EBI-2946349|uniprotkb:L0T6C9|uniprotkb:Q11053	psi-mi:acr_myctu(display_long)|uniprotkb:hspX(gene name)|psi-mi:hspX(display_short)|uniprotkb:acr(gene name synonym)|uniprotkb:14 kDa antigen(gene name synonym)|uniprotkb:16 kDa antigen(gene name synonym)|uniprotkb:HSP 16.3(gene name synonym)|uniprotkb:Nox16(gene name synonym)|uniprotkb:MTV018.18c(orf name)|uniprotkb:Rv2031c(locus name)	psi-mi:pknh_myctu(display_long)|uniprotkb:pknH(gene name)|psi-mi:pknH(display_short)|uniprotkb:MTCY50.16(orf name)|uniprotkb:Rv1266c(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946375|imex:IM-15201-13	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009408"(response to heat)|go:"GO:0010039"(response to iron ion)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0052572"(response to host immune response)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0075136"(response to host)|go:"GO:0001666"(response to hypoxia)|refseq:NP_216547.1|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|refseq:WP_003410189.1|interpro:IPR031107	go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0052572"(response to host immune response)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|refseq:NP_215782.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rcsb pdb:4ESQ|refseq:WP_010886110.1|interpro:IPR026954|interpro:IPR038232	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Phosphorylation of HspX.|figure legend:Fig 3A.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:zABUvnZ/UUuhnsNaCM5nJCxYsHY83332	rogid:vHWTiWUHoZsObF3tyUSLQSJiiEI83332	intact-crc:6613135861A617D8|rigid:EErZUo14vGtyYZXKQ2FlYkVWByY	false	his tag:n-n|tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P9WI75	uniprotkb:P9WPE7	intact:EBI-2945875|uniprotkb:L0T7T0|uniprotkb:O08151|uniprotkb:P72003	intact:EBI-2945826|uniprotkb:L0T3Q6|uniprotkb:P06806|uniprotkb:Q48920|uniprotkb:Q48931|uniprotkb:P0A520	psi-mi:pknf_myctu(display_long)|uniprotkb:pknF(gene name)|psi-mi:pknF(display_short)|uniprotkb:MTCY28.09(orf name)|uniprotkb:Rv1746(locus name)	psi-mi:ch602_myctu(display_long)|uniprotkb:groEL2(gene name)|psi-mi:groEL2(display_short)|uniprotkb:65 kDa antigen(gene name synonym)|uniprotkb:Antigen A(gene name synonym)|uniprotkb:Cell wall protein A(gene name synonym)|uniprotkb:Heat shock protein 65(gene name synonym)|uniprotkb:groL2(gene name synonym)|uniprotkb:hsp65(gene name synonym)|uniprotkb:60 kDa chaperonin 2(gene name synonym)|uniprotkb:Chaperonin-60 2(gene name synonym)|uniprotkb:cpn60.2(gene name synonym)|uniprotkb:mtc28(orf name)|uniprotkb:Rv0440(locus name)|uniprotkb:MTV037.04(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Molle et al. (2010)	pubmed:20925060|imex:IM-15201	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2946184|imex:IM-15201-14	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000921"(septin ring assembly)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|refseq:NP_216262.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|refseq:WP_003899000.1	go:"GO:0001666"(response to hypoxia)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0009408"(response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042603"(capsule)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1990220"(GroEL-GroES complex)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|refseq:NP_214954.1|interpro:IPR018370|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|rcsb pdb:1SJP|rcsb pdb:3RTK|refseq:WP_003402236.1|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:"Three distinct phosphorylated residues (on GroEL2)were identified."|figure legend:Fig 2C.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/25	2014/10/16	rogid:C97FRlJERgQL0geXkkP9hwJEwCk83332	rogid:C6siOCo/hWBtmYmu77f2SDtnAaU83332	intact-crc:35F3739EEF3A0473|rigid:IbwwENUb0oq4eDFqCh8+Q22Swlo	false	-	his tag:n-n|tag:?-?	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)