#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-8417907	uniprotkb:P55212	intact:MINT-8057600	intact:EBI-718729|uniprotkb:Q9BQE7|ensembl:ENSP00000265164	psi-mi:act-veid(display_short)|psi-mi:EBI-8417907(display_long)	psi-mi:casp6_human(display_long)|uniprotkb:Apoptotic protease Mch-2(gene name synonym)|uniprotkb:CASP6(gene name)|psi-mi:CASP6(display_short)|uniprotkb:MCH2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wang et al. (2010)	pubmed:20890311|imex:IM-15188|mint:MINT-8057576|doi:10.1038/embor.2010.141	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8417912|mint:MINT-8057582|imex:IM-15188-1	-	-	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	mint:MINT-8057602(identity)	refseq:NP_001217.2|refseq:NP_116787.1|rcsb pdb:3K7E|rcsb pdb:3NKF|rcsb pdb:3NR2|rcsb pdb:3OD5|rcsb pdb:3P45|rcsb pdb:3P4U|rcsb pdb:3QNW|rcsb pdb:3S70|rcsb pdb:3S8E|rcsb pdb:3V6L|rcsb pdb:3V6M|rcsb pdb:4EJF|rcsb pdb:4FXO|rcsb pdb:4HVA|rcsb pdb:4IYR|rcsb pdb:4N5D|rcsb pdb:4N6G|rcsb pdb:4N7J|rcsb pdb:4N7M|rcsb pdb:4NBK|rcsb pdb:4NBL|rcsb pdb:4NBN|rcsb pdb:6DEU|rcsb pdb:6DEV|reactome:R-HSA-111465|reactome:R-HSA-264870|reactome:R-HSA-352238|reactome:R-HSA-6803207|ensembl:ENSG00000138794(gene)|ensembl:ENST00000265164(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR037554|mint:P55212|rcsb pdb:1MI9|rcsb pdb:2WDP|dip:DIP-44649N|mint:MINT-8057584(identity)	-	comment:mint|no-uniprot-update:|comment:"Stoichiometry: 2.2"	comment:"Stoichiometry: 2.2"	comment:mint|figure legend:t1 f2b f2c f2e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/12	2022/01/21	rogid:kp+5RsQCVt90lWFcZym1qgujdGM-2	rogid:x335dTT6omZBrEGs7jzxOjUWaNM9606	intact-crc:41F5DC8DA66BCB6E|rigid:XJKmyeNm6wkDOVVgn/MH/4ukgfM	false	-	-	2	2	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P55212	uniprotkb:P55212	intact:EBI-718729|uniprotkb:Q9BQE7|ensembl:ENSP00000265164	intact:EBI-718729|uniprotkb:Q9BQE7|ensembl:ENSP00000265164	psi-mi:casp6_human(display_long)|uniprotkb:Apoptotic protease Mch-2(gene name synonym)|uniprotkb:CASP6(gene name)|psi-mi:CASP6(display_short)|uniprotkb:MCH2(gene name synonym)	psi-mi:casp6_human(display_long)|uniprotkb:Apoptotic protease Mch-2(gene name synonym)|uniprotkb:CASP6(gene name)|psi-mi:CASP6(display_short)|uniprotkb:MCH2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Wang et al. (2010)	pubmed:20890311|imex:IM-15188|mint:MINT-8057576|doi:10.1038/embor.2010.141	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8417926|mint:MINT-8057590|imex:IM-15188-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001217.2|refseq:NP_116787.1|rcsb pdb:3K7E|rcsb pdb:3NKF|rcsb pdb:3NR2|rcsb pdb:3OD5|rcsb pdb:3P45|rcsb pdb:3P4U|rcsb pdb:3QNW|rcsb pdb:3S70|rcsb pdb:3S8E|rcsb pdb:3V6L|rcsb pdb:3V6M|rcsb pdb:4EJF|rcsb pdb:4FXO|rcsb pdb:4HVA|rcsb pdb:4IYR|rcsb pdb:4N5D|rcsb pdb:4N6G|rcsb pdb:4N7J|rcsb pdb:4N7M|rcsb pdb:4NBK|rcsb pdb:4NBL|rcsb pdb:4NBN|rcsb pdb:6DEU|rcsb pdb:6DEV|reactome:R-HSA-111465|reactome:R-HSA-264870|reactome:R-HSA-352238|reactome:R-HSA-6803207|ensembl:ENSG00000138794(gene)|ensembl:ENST00000265164(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR037554|mint:P55212|rcsb pdb:1MI9|rcsb pdb:2WDP|dip:DIP-44649N|mint:MINT-8057592(identity)	refseq:NP_001217.2|refseq:NP_116787.1|rcsb pdb:3K7E|rcsb pdb:3NKF|rcsb pdb:3NR2|rcsb pdb:3OD5|rcsb pdb:3P45|rcsb pdb:3P4U|rcsb pdb:3QNW|rcsb pdb:3S70|rcsb pdb:3S8E|rcsb pdb:3V6L|rcsb pdb:3V6M|rcsb pdb:4EJF|rcsb pdb:4FXO|rcsb pdb:4HVA|rcsb pdb:4IYR|rcsb pdb:4N5D|rcsb pdb:4N6G|rcsb pdb:4N7J|rcsb pdb:4N7M|rcsb pdb:4NBK|rcsb pdb:4NBL|rcsb pdb:4NBN|rcsb pdb:6DEU|rcsb pdb:6DEV|reactome:R-HSA-111465|reactome:R-HSA-264870|reactome:R-HSA-352238|reactome:R-HSA-6803207|ensembl:ENSG00000138794(gene)|ensembl:ENST00000265164(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0072734"(cellular response to staurosporine)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR037554|mint:P55212|rcsb pdb:1MI9|rcsb pdb:2WDP|dip:DIP-44649N|mint:MINT-8057592(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	comment:mint|figure legend:t1 f2a f2d sf1a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/12	2014/10/16	rogid:x335dTT6omZBrEGs7jzxOjUWaNM9606	rogid:x335dTT6omZBrEGs7jzxOjUWaNM9606	intact-crc:FB646AF546D4F337|rigid:o55/mCmJFfD54JfemFnkWpPQdg0	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)