#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q95168	uniprotkb:E3Q1N2	intact:EBI-8304003|intact:UNK-5982363	intact:EBI-8310421|intact:MINT-8057259	psi-mi:zo2_canlf(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:ZO2(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)	psi-mi:e3q1n2_human(display_long)|uniprotkb:ZASP(gene name)|psi-mi:ZASP(display_short)	psi-mi:"MI:0397"(two hybrid array)	Lechuga et al. (2010)	pubmed:20868680|imex:IM-15329|mint:MINT-8057244|doi:10.1016/j.yexcr.2010.09.008	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8310415|mint:MINT-8057256|imex:IM-15329-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR035598|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR001452(Src homology-3)|interpro:IPR005417(Zona occludens protein)|refseq:NP_001003204.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR036028|interpro:IPR036034|mint:MINT-8057258(identity)	refseq:NP_001276862.1|mint:MINT-8057261(identity)	-	comment:mint|function:Plays a role in tight junctions and adherens junctions	comment:mint	figure legend:nfa|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2010/11/09	2014/10/16	rogid:KeIts4yOBOGSGpyKGhmUSav/9BA9615	rogid:nFSUGAaU1qJxvrdh0Zaxy3jRY7Q9606	intact-crc:083335FF8DB4F794|rigid:C/9NTbhS1eBvN8RY+UxeaO9+WKc	false	fusion protein:?-?(MINT-8057344)	fusion protein:?-?(MINT-8057341)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:E3Q1N2	uniprotkb:Q95168	intact:EBI-8310421|intact:MINT-8057259	intact:EBI-8304003|intact:UNK-5982363	psi-mi:e3q1n2_human(display_long)|uniprotkb:ZASP(gene name)|psi-mi:ZASP(display_short)	psi-mi:zo2_canlf(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:ZO2(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lechuga et al. (2010)	pubmed:20868680|imex:IM-15329|mint:MINT-8057244|doi:10.1016/j.yexcr.2010.09.008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8310465|mint:MINT-8057348|imex:IM-15329-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276862.1|mint:MINT-8057354(identity)	interpro:IPR035598|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR001452(Src homology-3)|interpro:IPR005417(Zona occludens protein)|refseq:NP_001003204.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR036028|interpro:IPR036034|mint:MINT-8057350(identity)	-	comment:mint	comment:mint|function:Plays a role in tight junctions and adherens junctions	figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2010/11/09	2014/10/16	rogid:nFSUGAaU1qJxvrdh0Zaxy3jRY7Q9606	rogid:KeIts4yOBOGSGpyKGhmUSav/9BA9615	intact-crc:F61A388FECC78243|rigid:C/9NTbhS1eBvN8RY+UxeaO9+WKc	false	his tag:?-?(MINT-8057355)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:E3Q1N2	uniprotkb:Q95168	intact:EBI-8310421|intact:MINT-8057259	intact:EBI-8304003|intact:UNK-5982363	psi-mi:e3q1n2_human(display_long)|uniprotkb:ZASP(gene name)|psi-mi:ZASP(display_short)	psi-mi:zo2_canlf(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:ZO2(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lechuga et al. (2010)	pubmed:20868680|imex:IM-15329|mint:MINT-8057244|doi:10.1016/j.yexcr.2010.09.008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8310489|mint:MINT-8057384|imex:IM-15329-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276862.1|mint:MINT-8057388(identity)	interpro:IPR035598|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR001452(Src homology-3)|interpro:IPR005417(Zona occludens protein)|refseq:NP_001003204.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR036028|interpro:IPR036034|mint:MINT-8057386(identity)	-	comment:mint	comment:mint|function:Plays a role in tight junctions and adherens junctions	figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/09	2014/10/16	rogid:nFSUGAaU1qJxvrdh0Zaxy3jRY7Q9606	rogid:KeIts4yOBOGSGpyKGhmUSav/9BA9615	intact-crc:C7D26CC7F6D0C568|rigid:C/9NTbhS1eBvN8RY+UxeaO9+WKc	false	glutathione s tranferase tag:?-?(MINT-8057389)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:E3Q1N2	uniprotkb:Q95168	intact:EBI-8310421|intact:MINT-8057259	intact:EBI-8304003|intact:UNK-5982363	psi-mi:e3q1n2_human(display_long)|uniprotkb:ZASP(gene name)|psi-mi:ZASP(display_short)	psi-mi:zo2_canlf(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:ZO2(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lechuga et al. (2010)	pubmed:20868680|imex:IM-15329|mint:MINT-8057244|doi:10.1016/j.yexcr.2010.09.008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8310504|mint:MINT-8057397|imex:IM-15329-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276862.1|mint:MINT-8057401(identity)	interpro:IPR035598|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR001452(Src homology-3)|interpro:IPR005417(Zona occludens protein)|refseq:NP_001003204.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR036028|interpro:IPR036034|mint:MINT-8057399(identity)	-	comment:mint	comment:mint|function:Plays a role in tight junctions and adherens junctions	figure legend:f3b|comment:homomint|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/09	2014/10/16	rogid:nFSUGAaU1qJxvrdh0Zaxy3jRY7Q9606	rogid:KeIts4yOBOGSGpyKGhmUSav/9BA9615	intact-crc:8969558842E11266|rigid:C/9NTbhS1eBvN8RY+UxeaO9+WKc	false	glutathione s tranferase tag:?-?(MINT-8057402)	binding-associated region:400-874(MINT-8057407)	-	-	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0113"(western blot)
uniprotkb:E3Q1N2	uniprotkb:Q95168	intact:EBI-8310421|intact:MINT-8057259	intact:EBI-8304003|intact:UNK-5982363	psi-mi:e3q1n2_human(display_long)|uniprotkb:ZASP(gene name)|psi-mi:ZASP(display_short)	psi-mi:zo2_canlf(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:ZO2(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lechuga et al. (2010)	pubmed:20868680|imex:IM-15329|mint:MINT-8057244|doi:10.1016/j.yexcr.2010.09.008	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8310535|mint:MINT-8057369|imex:IM-15329-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001276862.1|mint:MINT-8057373(identity)	interpro:IPR035598|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0009986"(cell surface)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR001452(Src homology-3)|interpro:IPR005417(Zona occludens protein)|refseq:NP_001003204.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR036028|interpro:IPR036034|mint:MINT-8057371(identity)	-	comment:mint	comment:mint|function:Plays a role in tight junctions and adherens junctions	figure legend:f2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2010/11/09	2014/10/16	rogid:nFSUGAaU1qJxvrdh0Zaxy3jRY7Q9606	rogid:KeIts4yOBOGSGpyKGhmUSav/9BA9615	intact-crc:F044F955E9FD2E00|rigid:C/9NTbhS1eBvN8RY+UxeaO9+WKc	false	his tag:?-?(MINT-8057374)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)