#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:60279" uniprotkb:D3Z7P3 intact:EBI-2928401 intact:EBI-2928377|ensembl:ENSMUSP00000110158|uniprotkb:E9PUF0|uniprotkb:Q69ZX9 psi-mi:968(display_short)|psi-mi:"CHEBI:60279"(display_long) psi-mi:glsk_mouse(display_long)|uniprotkb:Gls(gene name)|psi-mi:Gls(display_short)|uniprotkb:Gls1(gene name synonym)|uniprotkb:Kiaa0838(gene name synonym) psi-mi:"MI:0415"(enzymatic study) Wang et al. (2010) pubmed:20832749 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2928376 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000026103(gene)|ensembl:ENSMUST00000114513(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|interpro:IPR041541|rcsb pdb:3SS3|rcsb pdb:3SS4|rcsb pdb:3SS5|rcsb pdb:4JKT|rcsb pdb:5W2J|reactome:R-MMU-210500|reactome:R-MMU-5628897|reactome:R-MMU-8964539|refseq:NP_001074550.1|refseq:NP_001106854.1|dip:DIP-60006N - caution:"(5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a])is the name given in PMID: 20832749." - figure legend:Fig 5A.|kinetics:V max = 620 mol of glutamine hydrolyzed per minute per mol of enzyme.|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/09/21 2014/10/16 - rogid:Wa7AVXLSYKKwn7woBL0QfUFHIVs10090 intact-crc:B3C64A9528367A57 false - sufficient binding region:128-603 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60279" chebi:"CHEBI:28300" intact:EBI-2928401 intact:EBI-2928394 psi-mi:968(display_short)|psi-mi:"CHEBI:60279"(display_long) psi-mi:glutamine(display_short)|psi-mi:"CHEBI:28300"(display_long) psi-mi:"MI:0415"(enzymatic study) Wang et al. (2010) pubmed:20832749 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2928376 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0586"(inhibitor) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0328"(small molecule) - - - caution:"(5-[3-bromo-4-(dimethylamino)phenyl]-2,2-dimethyl-2,3,5,6-tetrahydrobenzo[a])is the name given in PMID: 20832749." - figure legend:Fig 5A.|kinetics:V max = 620 mol of glutamine hydrolyzed per minute per mol of enzyme.|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/09/21 2014/10/16 - - intact-crc:B3C64A9528367A57 false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) chebi:"CHEBI:60278" uniprotkb:D3Z7P3 intact:EBI-2928403 intact:EBI-2928377|ensembl:ENSMUSP00000110158|uniprotkb:E9PUF0|uniprotkb:Q69ZX9 psi-mi:active_968_biotin(display_short)|psi-mi:"CHEBI:60278"(display_long) psi-mi:glsk_mouse(display_long)|uniprotkb:Gls(gene name)|psi-mi:Gls(display_short)|uniprotkb:Gls1(gene name synonym)|uniprotkb:Kiaa0838(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2010) pubmed:20832749 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2928421 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000026103(gene)|ensembl:ENSMUST00000114513(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|interpro:IPR041541|rcsb pdb:3SS3|rcsb pdb:3SS4|rcsb pdb:3SS5|rcsb pdb:4JKT|rcsb pdb:5W2J|reactome:R-MMU-210500|reactome:R-MMU-5628897|reactome:R-MMU-8964539|refseq:NP_001074550.1|refseq:NP_001106854.1|dip:DIP-60006N - - - figure legend:Fig 5A.|dataset:Cancer - Interactions investigated in the context of cancer taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2010/09/21 2014/10/16 - rogid:Wa7AVXLSYKKwn7woBL0QfUFHIVs10090 intact-crc:186C2B5891B20DF8 false - v5 tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) chebi:"CHEBI:60278" uniprotkb:D3Z7P3 intact:EBI-2928403 intact:EBI-2928377|ensembl:ENSMUSP00000110158|uniprotkb:E9PUF0|uniprotkb:Q69ZX9 psi-mi:active_968_biotin(display_short)|psi-mi:"CHEBI:60278"(display_long) psi-mi:glsk_mouse(display_long)|uniprotkb:Gls(gene name)|psi-mi:Gls(display_short)|uniprotkb:Gls1(gene name synonym)|uniprotkb:Kiaa0838(gene name synonym) psi-mi:"MI:0096"(pull down) Wang et al. (2010) pubmed:20832749 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2928442 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSMUSG00000026103(gene)|ensembl:ENSMUST00000114513(transcript)|go:"GO:0001967"(suckling behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0004359"(glutaminase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0090461"(glutamate homeostasis)|interpro:IPR002110(Ankyrin)|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR020683|interpro:IPR036770|interpro:IPR041541|rcsb pdb:3SS3|rcsb pdb:3SS4|rcsb pdb:3SS5|rcsb pdb:4JKT|rcsb pdb:5W2J|reactome:R-MMU-210500|reactome:R-MMU-5628897|reactome:R-MMU-8964539|refseq:NP_001074550.1|refseq:NP_001106854.1|dip:DIP-60006N - - - figure legend:Fig S2A.|dataset:Cancer - Interactions investigated in the context of cancer taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2010/09/21 2014/10/16 - rogid:Wa7AVXLSYKKwn7woBL0QfUFHIVs10090 intact-crc:8A65EED8F2797E84 false - identified peptide:580-595 - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry)