#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9WTL8	uniprotkb:Q9R194	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931499|imex:IM-15197-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Figs. 3B, 3E, 4B|comment:In both wild-type and PARP-1-/- mice, immunoprecipitation of BMAL1 resulted in coimmunoprecipitation of CLOCK, indicating that the interaction between BMAL1 and CLOCK is not dependent on PARP-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090	intact-crc:3348B362A451AC97|rigid:prm/EW6i9vMMsMR5T3/kVjxT1Pc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O08785	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931499|imex:IM-15197-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Figs. 3B, 3E, 4B|comment:In both wild-type and PARP-1-/- mice, immunoprecipitation of BMAL1 resulted in coimmunoprecipitation of CLOCK, indicating that the interaction between BMAL1 and CLOCK is not dependent on PARP-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:3348B362A451AC97|rigid:prm/EW6i9vMMsMR5T3/kVjxT1Pc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O54943	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266779|uniprotkb:O54954	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931499|imex:IM-15197-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Figs. 3B, 3E, 4B|comment:In both wild-type and PARP-1-/- mice, immunoprecipitation of BMAL1 resulted in coimmunoprecipitation of CLOCK, indicating that the interaction between BMAL1 and CLOCK is not dependent on PARP-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090	intact-crc:3348B362A451AC97|rigid:prm/EW6i9vMMsMR5T3/kVjxT1Pc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P97784	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266607|ensembl:ENSMUSP00000020227	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931499|imex:IM-15197-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm)	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Figs. 3B, 3E, 4B|comment:In both wild-type and PARP-1-/- mice, immunoprecipitation of BMAL1 resulted in coimmunoprecipitation of CLOCK, indicating that the interaction between BMAL1 and CLOCK is not dependent on PARP-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090	intact-crc:3348B362A451AC97|rigid:prm/EW6i9vMMsMR5T3/kVjxT1Pc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P11103	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931499|imex:IM-15197-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Figs. 3B, 3E, 4B|comment:In both wild-type and PARP-1-/- mice, immunoprecipitation of BMAL1 resulted in coimmunoprecipitation of CLOCK, indicating that the interaction between BMAL1 and CLOCK is not dependent on PARP-1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	intact-crc:3348B362A451AC97|rigid:prm/EW6i9vMMsMR5T3/kVjxT1Pc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O08785	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931507|imex:IM-15197-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:CF73C924BA5480DD|rigid:EHrO2y2Rr47RvDjuolQLkkPWoIg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P97784	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266607|ensembl:ENSMUSP00000020227	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931507|imex:IM-15197-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm)	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090	intact-crc:CF73C924BA5480DD|rigid:EHrO2y2Rr47RvDjuolQLkkPWoIg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P97784	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266607|ensembl:ENSMUSP00000020227	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931513|imex:IM-15197-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm)	go:"GO:0005634"(nucleus)	-	-	variable_condition:8|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090	intact-crc:A373C924BA54896B|rigid:EHrO2y2Rr47RvDjuolQLkkPWoIg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O08785	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931513|imex:IM-15197-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:8|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:A373C924BA54896B|rigid:EHrO2y2Rr47RvDjuolQLkkPWoIg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:Q9R194	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931519|imex:IM-15197-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9	go:"GO:0005634"(nucleus)	-	-	variable_condition:12|figure legend:Figs. 3B,4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090	intact-crc:753CB0BCFF6284C3|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O08785	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931519|imex:IM-15197-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:12|figure legend:Figs. 3B,4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:753CB0BCFF6284C3|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P97784	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266607|ensembl:ENSMUSP00000020227	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931519|imex:IM-15197-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm)	go:"GO:0005634"(nucleus)	-	-	variable_condition:12|figure legend:Figs. 3B,4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090	intact-crc:753CB0BCFF6284C3|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O54943	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266779|uniprotkb:O54954	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931519|imex:IM-15197-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H	go:"GO:0005634"(nucleus)	-	-	variable_condition:12|figure legend:Figs. 3B,4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090	intact-crc:753CB0BCFF6284C3|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:Q9R194	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931526|imex:IM-15197-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090	intact-crc:48F66E0D7CFF65E9|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O54943	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266779|uniprotkb:O54954	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931526|imex:IM-15197-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090	intact-crc:48F66E0D7CFF65E9|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O08785	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931526|imex:IM-15197-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:48F66E0D7CFF65E9|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P97784	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266607|ensembl:ENSMUSP00000020227	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931526|imex:IM-15197-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm)	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090	intact-crc:48F66E0D7CFF65E9|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O54943	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266779|uniprotkb:O54954	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931533|imex:IM-15197-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H	go:"GO:0005634"(nucleus)	-	-	variable_condition:20|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090	intact-crc:2EC56E0D7CFF6130|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:Q9R194	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266619|uniprotkb:O08706|uniprotkb:Q6A024|ensembl:ENSMUSP00000088047|ensembl:ENSMUSP00000106909	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry2_mouse(display_long)|uniprotkb:Cry2(gene name)|psi-mi:Cry2(display_short)|uniprotkb:Kiaa0658(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931533|imex:IM-15197-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_034093.1|refseq:XP_017170770.1|dip:DIP-38517N|ensembl:ENSMUSG00000068742(gene)|ensembl:ENSMUST00000090559(transcript)|ensembl:ENSMUST00000111278(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071949"(FAD binding)|go:"GO:2000118"(regulation of sodium-dependent phosphate transport)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:Q9R194|rcsb pdb:4I6E|rcsb pdb:4I6G|rcsb pdb:4I6J|rcsb pdb:4MLP|rcsb pdb:4U8H|rcsb pdb:6KX8|rcsb pdb:7D0N|rcsb pdb:7EJ9	go:"GO:0005634"(nucleus)	-	-	variable_condition:20|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:00SKIwCL33BKjjyPSsxZUR5Sjbs10090	intact-crc:2EC56E0D7CFF6130|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:O08785	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931533|imex:IM-15197-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:20|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:2EC56E0D7CFF6130|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P97784	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-1266607|ensembl:ENSMUSP00000020227	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:cry1_mouse(display_long)|uniprotkb:Cry1(gene name)|psi-mi:Cry1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931533|imex:IM-15197-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	refseq:NP_031797.1|dip:DIP-38515N|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033762"(response to glucagon)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070888"(E-box binding)|go:"GO:0071949"(FAD binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000850"(negative regulation of glucocorticoid secretion)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|mint:P97784|rcsb pdb:4CT0|rcsb pdb:4K0R|rcsb pdb:5T5X|rcsb pdb:6KX4|rcsb pdb:6KX5|rcsb pdb:6KX6|rcsb pdb:6KX7|rcsb pdb:6LUE|rcsb pdb:6OF7|rcsb pdb:7D0M|rcsb pdb:7D19|rcsb pdb:7D1C|rcsb pdb:7DLI|ensembl:ENSMUSG00000020038(gene)|ensembl:ENSMUST00000020227(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006975"(DNA damage induced protein phosphorylation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0014823"(response to activity)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032868"(response to insulin)|go:"GO:0005654"(nucleoplasm)	go:"GO:0005634"(nucleus)	-	-	variable_condition:20|figure legend:Figs. 3B, 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:V0etJNAuSn2k4pmE9bZ0UWpv8SM10090	intact-crc:2EC56E0D7CFF6130|rigid:AS4cUxXeDEGGV0RA4ieVNrz2eqw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9WTL8	uniprotkb:P11103	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3134490|imex:IM-15197-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	go:"GO:0005634"(nucleus)	-	-	variable_condition:8|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	intact-crc:B2FAF61371947007|rigid:LzEmilSVLvbVih+uEY8gzdYI6VY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:P11103	intact:EBI-2931710	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931718|imex:IM-15197-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|comment:"Interaction between ADP-ribose and Clock observed in parp1 -/- cells. Clock remained associated with ADP-ribose even under harsh denaturing conditions (1% SDS) which removed PARP1"|figure legend:Figs. 3G, Supp. Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	intact-crc:76E8D5871D8C6F77	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:O08785	intact:EBI-2931710	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931718|imex:IM-15197-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|comment:"Interaction between ADP-ribose and Clock observed in parp1 -/- cells. Clock remained associated with ADP-ribose even under harsh denaturing conditions (1% SDS) which removed PARP1"|figure legend:Figs. 3G, Supp. Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:76E8D5871D8C6F77	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:O08785	intact:EBI-2931710	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931889|imex:IM-15197-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Figs. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:F752A5036A457BBB	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:O08785	intact:EBI-2931710	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931896|imex:IM-15197-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|figure legend:Figs. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:F752A26EAA457BBB	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:O08785	intact:EBI-2931710	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931902|imex:IM-15197-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:8|figure legend:Figs. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:F752ABD8EA457BBB	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:O08785	intact:EBI-2931710	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931908|imex:IM-15197-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:12|figure legend:Figs. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:2BF52CE0AF7FF157	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:O08785	intact:EBI-2931710	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931914|imex:IM-15197-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Figs. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:2BF52B8D6F7FF157	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:16864"	uniprotkb:O08785	intact:EBI-2931710	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:adp-ribose(display_short)|psi-mi:"CHEBI:16864"(display_long)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931920|imex:IM-15197-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:20|figure legend:Figs. 3I|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	-	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:2BF52F5422EFF157	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O08785	uniprotkb:P11103	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931582|imex:IM-15197-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	intact-crc:78FD6F9D7ECFC01E|rigid:aUv7+IniQFyX4AR9+dkfTyrMp3s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O08785	uniprotkb:Q9WTL8	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931582|imex:IM-15197-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:78FD6F9D7ECFC01E|rigid:aUv7+IniQFyX4AR9+dkfTyrMp3s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O08785	uniprotkb:O54943	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	intact:EBI-1266779|uniprotkb:O54954	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:per2_mouse(display_long)|uniprotkb:Per2(gene name)|psi-mi:Per2(display_short)|uniprotkb:Circadian clock protein PERIOD 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931588|imex:IM-15197-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	refseq:NP_035196.2|mint:O54943|dip:DIP-38518N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051946"(regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0060567"(negative regulation of DNA-templated transcription, termination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR000014(PAS)|interpro:IPR013655(PAS fold-3)|interpro:IPR022728|interpro:IPR035965|rcsb pdb:3GDI|rcsb pdb:4CT0|rcsb pdb:4U8H	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	rogid:bA+e5kx1ZkqfPRHn3TDAuhmqAw410090	intact-crc:D770E4A525EC81F6|rigid:9fY3qmz/+t/3bcjZiS9IjT2aZyg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O08785	uniprotkb:Q9WTL8	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931588|imex:IM-15197-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:D770E4A525EC81F6|rigid:9fY3qmz/+t/3bcjZiS9IjT2aZyg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11103	uniprotkb:O08785	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931539|imex:IM-15197-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:04122DA0842B77A7|rigid:aUv7+IniQFyX4AR9+dkfTyrMp3s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11103	uniprotkb:Q9WTL8	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931539|imex:IM-15197-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:0005634"(nucleus)	-	-	variable_condition:0|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:04122DA0842B77A7|rigid:aUv7+IniQFyX4AR9+dkfTyrMp3s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11103	uniprotkb:O08785	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931545|imex:IM-15197-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:04154060842B77A7|rigid:aUv7+IniQFyX4AR9+dkfTyrMp3s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11103	uniprotkb:Q9WTL8	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931545|imex:IM-15197-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:0005634"(nucleus)	-	-	variable_condition:4|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:04154060842B77A7|rigid:aUv7+IniQFyX4AR9+dkfTyrMp3s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11103	uniprotkb:Q9WTL8	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931551|imex:IM-15197-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:0005634"(nucleus)	-	-	variable_condition:12|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:10182CEE2FC022F9|rigid:LzEmilSVLvbVih+uEY8gzdYI6VY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11103	uniprotkb:Q9WTL8	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931556|imex:IM-15197-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:0005634"(nucleus)	-	-	variable_condition:16|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:101F412E2FC022F9|rigid:LzEmilSVLvbVih+uEY8gzdYI6VY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11103	uniprotkb:Q9WTL8	intact:EBI-642213|uniprotkb:Q9JLX4|uniprotkb:Q9QVQ3	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:parp1_mouse(display_long)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Parp1(gene name)|psi-mi:Parp1(display_short)|uniprotkb:Adprp(gene name synonym)|uniprotkb:Adprt(gene name synonym)|uniprotkb:Adprt1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931561|imex:IM-15197-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|reactome:R-MMU-110362|reactome:R-MMU-2173795|reactome:R-MMU-3108214|reactome:R-MMU-5685939|reactome:R-MMU-5696394|reactome:R-MMU-5696395|reactome:R-MMU-5696400|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0040009"(regulation of growth rate)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0034644"(cellular response to UV)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071451"(cellular response to superoxide)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903516"(regulation of single strand break repair)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1903827"|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:0070212"(protein poly-ADP-ribosylation)|mint:P11103|dip:DIP-39371N	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	go:"GO:0005634"(nucleus)	-	-	variable_condition:20|figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-liver)|taxid:10090(Mus musculus)	-	2010/10/04	2014/10/16	rogid:ZJY1aTtD8Cz198SVs9FDdUSli7s10090	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:101B9863BFC022F9|rigid:LzEmilSVLvbVih+uEY8gzdYI6VY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P09874	uniprotkb:O08785	intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759	intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939	psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym)	psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short)	psi-mi:"MI:0096"(pull down)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-2931601|imex:IM-15197-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N	ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/10/04	2014/10/16	rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606	rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090	intact-crc:B1A17206D277DC04|rigid:4h3gJwJDcTxYmEMbtC30YaoMQb0	false	his tag:?-?|ha tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
intact:EBI-3134650	uniprotkb:Q9WTL8	-	intact:EBI-644534|uniprotkb:O88295|uniprotkb:Q921S4|uniprotkb:Q9R0U2|uniprotkb:Q9WTL9	psi-mi:g-box_probe(display_short)|psi-mi:EBI-3134650(display_long)	psi-mi:bmal1_mouse(display_long)|uniprotkb:Arntl(gene name)|psi-mi:Arntl(display_short)|uniprotkb:Bmal1(gene name synonym)|uniprotkb:Brain and muscle ARNT-like 1(gene name synonym)|uniprotkb:Arnt3(gene name synonym)	psi-mi:"MI:0412"(electrophoretic mobility supershift assay)	Asher et al. (2010)	pubmed:20832105|imex:IM-15197	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-3134652|imex:IM-15197-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0319"(deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000055866(see-also)	refseq:NP_001229977.1|refseq:NP_031515.1|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060137"(maternal process involved in parturition)|go:"GO:0070888"(E-box binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901985"(positive regulation of protein acetylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001016"(positive regulation of skeletal muscle cell differentiation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4F3L|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|refseq:XP_006507314.1|refseq:XP_017177438.1|refseq:XP_017177439.1|dip:DIP-43977N|mint:Q9WTL8	-	-	-	comment:G-box probe is radio-labelled.|figure legend:Supp. Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/10/04	2014/10/16	crc64:10AD93FF2E7422EA	rogid:dZsboMuYuWHsdO5D4p4DsYkZ9wY10090	intact-crc:F9712EF9FF7301CA	false	-	-	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)