#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8VSC3	uniprotkb:Q8VSC3	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1|ensemblbacteria:AAL72345	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1|ensemblbacteria:AAL72345	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen ipaH9.8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ipaH9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen ipaH9.8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ipaH9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Seyedarabi et al. (2010)	pubmed:20831869|imex:IM-15621|mint:MINT-7993746|mint:d-10-01382|doi:10.1016/j.febslet.2010.09.006	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:623(shifl)|taxid:623(Shigella flexneri)	psi-mi:"MI:0408"(disulfide bond)	psi-mi:"MI:0471"(MINT)	intact:EBI-8299337|mint:MINT-7993779|imex:IM-15621-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858359.2|refseq:YP_006960318.1|refseq:WP_010921715.1|dip:DIP-46341N|ensemblbacteria:AAL72345(transcript)|ensemblbacteria:SF_p0226(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|mint:MINT-7993781(identity)	refseq:NP_858359.2|refseq:YP_006960318.1|refseq:WP_010921715.1|dip:DIP-46341N|ensemblbacteria:AAL72345(transcript)|ensemblbacteria:SF_p0226(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|mint:MINT-7993781(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	comment:mint|figure legend:t1 f4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/09/02	2014/10/16	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	intact-crc:6A7D05106CECB2F2|rigid:AjzfZDpBV81/h5q+S9HNcpQy+CY	false	binding-associated region:254-545(MINT-7993785)	binding-associated region:254-545(MINT-7993785)	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8VSC3	uniprotkb:Q8VSC3	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1|ensemblbacteria:AAL72345	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1|ensemblbacteria:AAL72345	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen ipaH9.8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ipaH9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen ipaH9.8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ipaH9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	psi-mi:"MI:0004"(affinity chromatography technology)	Seyedarabi et al. (2010)	pubmed:20831869|imex:IM-15621|mint:MINT-7993746|mint:d-10-01382|doi:10.1016/j.febslet.2010.09.006	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:623(shifl)|taxid:623(Shigella flexneri)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8299361|mint:MINT-7993812|imex:IM-15621-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858359.2|refseq:YP_006960318.1|refseq:WP_010921715.1|dip:DIP-46341N|ensemblbacteria:AAL72345(transcript)|ensemblbacteria:SF_p0226(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|mint:MINT-7993814(identity)	refseq:NP_858359.2|refseq:YP_006960318.1|refseq:WP_010921715.1|dip:DIP-46341N|ensemblbacteria:AAL72345(transcript)|ensemblbacteria:SF_p0226(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|mint:MINT-7993814(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:f1c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/09/02	2014/10/16	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	intact-crc:CB83E6B900414DFF|rigid:AjzfZDpBV81/h5q+S9HNcpQy+CY	false	his tag:?-?(MINT-7993817)	his tag:?-?(MINT-7993817)	2	0	psi-mi:"MI:0815"(confirmation by molecular weight)	psi-mi:"MI:0815"(confirmation by molecular weight)
uniprotkb:Q8VSC3	uniprotkb:Q8VSC3	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1|ensemblbacteria:AAL72345	intact:EBI-6125799|uniprotkb:O85159|uniprotkb:Q2TH74|uniprotkb:Q6XVV1|uniprotkb:Q9AFM5|uniprotkb:Q9AJV1|ensemblbacteria:AAL72345	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen ipaH9.8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ipaH9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	psi-mi:ipa9_shifl(display_long)|uniprotkb:ipaH9.8(gene name)|psi-mi:ipaH9.8(display_short)|uniprotkb:Invasion plasmid antigen ipaH9.8(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ipaH9.8(gene name synonym)|uniprotkb:SFLP090(orf name)|uniprotkb:pWR501_0234(orf name)|uniprotkb:CP0226(locus name)	psi-mi:"MI:0276"(blue native page)	Seyedarabi et al. (2010)	pubmed:20831869|imex:IM-15621|mint:MINT-7993746|mint:d-10-01382|doi:10.1016/j.febslet.2010.09.006	taxid:623(shifl)|taxid:623(Shigella flexneri)	taxid:623(shifl)|taxid:623(Shigella flexneri)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8299384|mint:MINT-7993790|imex:IM-15621-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_858359.2|refseq:YP_006960318.1|refseq:WP_010921715.1|dip:DIP-46341N|ensemblbacteria:AAL72345(transcript)|ensemblbacteria:SF_p0226(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|mint:MINT-7993792(identity)	refseq:NP_858359.2|refseq:YP_006960318.1|refseq:WP_010921715.1|dip:DIP-46341N|ensemblbacteria:AAL72345(transcript)|ensemblbacteria:SF_p0226(gene)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044314"(protein K27-linked ubiquitination)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0085032"(modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade)|interpro:IPR029487|interpro:IPR032674|interpro:IPR032675|rcsb pdb:3L3P|rcsb pdb:5B0N|rcsb pdb:5B0T|rcsb pdb:6K2D|mint:MINT-7993792(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	figure legend:f1a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/09/02	2014/10/16	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	rogid:vkGhHfT9QMT1xPHgaxaJ0dFaYZw623	intact-crc:06A5EF8888C41289|rigid:AjzfZDpBV81/h5q+S9HNcpQy+CY	false	-	-	2	0	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)