#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UPW6 uniprotkb:Q9H3D4 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8298213|mint:MINT-8040525|imex:IM-15059-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8040527(identity) refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|mint:MINT-8040528(identity) - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" - figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hnscc)|taxid:9606(Homo sapiens) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606 intact-crc:007186A2E547ACA1|rigid:qTPdAwT4zCdydO7qXwcpI4ivwbU false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9UPW6 uniprotkb:Q9H3D4 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-2337775|uniprotkb:O75080|uniprotkb:O75195|uniprotkb:O75922|uniprotkb:O76078|uniprotkb:Q6VEG2|uniprotkb:Q6VEG3|uniprotkb:Q6VEG4|uniprotkb:Q6VFJ1|uniprotkb:Q6VFJ2|uniprotkb:Q6VFJ3|uniprotkb:Q6VH20|uniprotkb:Q7LDI3|uniprotkb:Q7LDI4|uniprotkb:Q7LDI5|uniprotkb:Q96KR0|uniprotkb:Q9H3D2|uniprotkb:Q9H3D3|uniprotkb:Q9H3P8|uniprotkb:Q9NPH7|uniprotkb:Q9P1B4|uniprotkb:Q9P1B5|uniprotkb:Q9P1B6|uniprotkb:Q9P1B7|uniprotkb:Q9UBV9|uniprotkb:Q9UE10|uniprotkb:Q9UP26|uniprotkb:Q9UP27|uniprotkb:Q9UP28|uniprotkb:Q9UP74|ensembl:ENSP00000264731 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:p63_human(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8298255|mint:MINT-8040535|imex:IM-15059-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8040537(identity) refseq:NP_001108450.1|refseq:NP_001108451.1|refseq:NP_001108452.1|refseq:NP_001108453.1|refseq:NP_001108454.1|refseq:NP_003713.3|ensembl:ENSP00000264731|ensembl:ENST00000320472|ensembl:ENSP00000317510|ensembl:ENST00000354600|ensembl:ENSP00000346614|ensembl:ENST00000392460|ensembl:ENSP00000376253|ensembl:ENST00000392461|ensembl:ENSP00000376254|ensembl:ENST00000392463|ensembl:ENSP00000376256|ensembl:ENST00000418709|ensembl:ENSP00000407144|ensembl:ENST00000437221|ensembl:ENSP00000392488|ensembl:ENST00000440651|ensembl:ENSP00000394337|ensembl:ENST00000449992|ensembl:ENSP00000387839|ensembl:ENST00000456148|ensembl:ENSP00000389485|refseq:NP_001316073.1|refseq:NP_001316074.1|refseq:NP_001316075.1|refseq:NP_001316077.1|refseq:XP_016862876.1|dip:DIP-29588N|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032645|interpro:IPR036674|interpro:IPR037611|mint:Q9H3D4|rcsb pdb:1RG6|rcsb pdb:2NB1|rcsb pdb:2RMN|rcsb pdb:2Y9T|rcsb pdb:2Y9U|rcsb pdb:3QYM|rcsb pdb:3QYN|rcsb pdb:3US0|rcsb pdb:3US1|rcsb pdb:3US2|rcsb pdb:3ZY0|rcsb pdb:3ZY1|rcsb pdb:4A9Z|rcsb pdb:6FGN|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-139915|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|interpro:IPR001660(Sterile alpha motif SAM)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0002039"(p53 binding)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007499"(ectoderm and mesoderm interaction)|go:"GO:0007569"(cell aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010481"(epidermal cell division)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048807"(female genitalia morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060197"(cloacal septation)|go:"GO:0060513"(prostatic bud formation)|go:"GO:0060529"(squamous basal epithelial stem cell differentiation involved in prostate gland acinus development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904674"(positive regulation of somatic stem cell population maintenance)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|go:"GO:2000381"(negative regulation of mesoderm development)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|mint:MINT-8040539(identity) go:"GO:0005634"(nucleus) comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" - figure legend:f3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-scc9)|taxid:9606(Homo sapiens) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606 intact-crc:B6CFC16751079114|rigid:qTPdAwT4zCdydO7qXwcpI4ivwbU false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9UPW6 uniprotkb:Q9H3D4-2 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-6481107|intact:EBI-8298432|intact:MINT-190363|intact:EBI-8298466|intact:EBI-8298325|intact:EBI-8298365|intact:EBI-8298641|ensembl:ENSP00000346614 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:q9h3d4-2(display_long)|uniprotkb:DeltaN-alpha(isoform synonym)|uniprotkb:DeltaNp63 alpha(isoform synonym)|uniprotkb:P51delNalpha(isoform synonym)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:p51(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8298319|mint:MINT-8040583|imex:IM-15059-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8040585(identity) intact:EBI-2337775(isoform-parent)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000354600(transcript)|mint:MINT-8040587(identity) - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" isoform-comment:"Produced by alternative promoter usage. Variant in position: 6:N->H (in ADULT syndrome)." comment:homomint|comment:mint|figure legend:f3a sf2a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:E0nFDEthzDn3LSMqOsn3LNOHKhc9606 intact-crc:6D36B82541D28D54|rigid:RpTEVLxghtxUY8IT2T55rPL2LKc false t7 tag:?-?(MINT-8040593) flag tag:?-?(MINT-8040596) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPW6 uniprotkb:Q9H3D4-2 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-6481107|intact:EBI-8298432|intact:MINT-190363|intact:EBI-8298466|intact:EBI-8298325|intact:EBI-8298365|intact:EBI-8298641|ensembl:ENSP00000346614 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:q9h3d4-2(display_long)|uniprotkb:DeltaN-alpha(isoform synonym)|uniprotkb:DeltaNp63 alpha(isoform synonym)|uniprotkb:P51delNalpha(isoform synonym)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:p51(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8298359|mint:MINT-8040614|imex:IM-15059-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8040616(identity) intact:EBI-2337775(isoform-parent)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000354600(transcript)|mint:MINT-8040620(identity) - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" isoform-comment:"Produced by alternative promoter usage. Variant in position: 6:N->H (in ADULT syndrome)." figure legend:sf2a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:E0nFDEthzDn3LSMqOsn3LNOHKhc9606 intact-crc:67D08FF2063E9F2D|rigid:RpTEVLxghtxUY8IT2T55rPL2LKc false - flag tag:?-?(MINT-8040621) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPW6 uniprotkb:Q9H3D4-2 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-6481107|intact:EBI-8298432|intact:MINT-190363|intact:EBI-8298466|intact:EBI-8298325|intact:EBI-8298365|intact:EBI-8298641|ensembl:ENSP00000346614 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:q9h3d4-2(display_long)|uniprotkb:DeltaN-alpha(isoform synonym)|uniprotkb:DeltaNp63 alpha(isoform synonym)|uniprotkb:P51delNalpha(isoform synonym)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:p51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8298505|mint:MINT-8040627|imex:IM-15059-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8040629(identity) intact:EBI-2337775(isoform-parent)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000354600(transcript)|mint:MINT-8040631(identity) - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" isoform-comment:"Produced by alternative promoter usage. Variant in position: 6:N->H (in ADULT syndrome)." figure legend:sf2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:E0nFDEthzDn3LSMqOsn3LNOHKhc9606 intact-crc:0574BD271362F279|rigid:RpTEVLxghtxUY8IT2T55rPL2LKc false t7 tag:?-?(MINT-8040638) flag tag:?-?(MINT-8040632) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPW6 uniprotkb:Q9H3D4-2 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-6481107|intact:EBI-8298432|intact:MINT-190363|intact:EBI-8298466|intact:EBI-8298325|intact:EBI-8298365|intact:EBI-8298641|ensembl:ENSP00000346614 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:q9h3d4-2(display_long)|uniprotkb:DeltaN-alpha(isoform synonym)|uniprotkb:DeltaNp63 alpha(isoform synonym)|uniprotkb:P51delNalpha(isoform synonym)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:p51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8298426|mint:MINT-8040599|imex:IM-15059-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8040601(identity) intact:EBI-2337775(isoform-parent)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000354600(transcript)|mint:MINT-8040605(identity) - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" isoform-comment:"Produced by alternative promoter usage. Variant in position: 6:N->H (in ADULT syndrome)." figure legend:f3a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:E0nFDEthzDn3LSMqOsn3LNOHKhc9606 intact-crc:DA1DD2BA437E166A|rigid:RpTEVLxghtxUY8IT2T55rPL2LKc false t7 tag:?-?(MINT-8040602) flag tag:?-?(MINT-8040606) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPW6 uniprotkb:Q9H3D4-1 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-2400586|intact:EBI-8033122|intact:MINT-190356|intact:EBI-8032875|intact:EBI-8298527|intact:EBI-8032929|intact:EBI-8033366|intact:EBI-8033036|intact:EBI-8032803|intact:EBI-8033435|ensembl:ENSP00000264731 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:q9h3d4-1(display_long)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:p51(gene name synonym)|uniprotkb:TA*-alpha(isoform synonym)|uniprotkb:TAp63alpha(isoform synonym)|uniprotkb:P51B(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8298549|mint:MINT-8040642|imex:IM-15059-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8040644(identity) intact:EBI-2337775(isoform-parent)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000264731(transcript)|mint:MINT-8040648(identity) - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" isoform-comment:Produced by alternative promoter usage. figure legend:sf2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:dwFwax9/monTAo8mJp1y7aGh+Cs9606 intact-crc:AA74BD279FB70515|rigid:qTPdAwT4zCdydO7qXwcpI4ivwbU false t7 tag:?-?(MINT-8040645) flag tag:?-?(MINT-8040649) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UPW6 uniprotkb:Q9H3D4-2 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-6481107|intact:EBI-8298432|intact:MINT-190363|intact:EBI-8298466|intact:EBI-8298325|intact:EBI-8298365|intact:EBI-8298641|ensembl:ENSP00000346614 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:q9h3d4-2(display_long)|uniprotkb:DeltaN-alpha(isoform synonym)|uniprotkb:DeltaNp63 alpha(isoform synonym)|uniprotkb:P51delNalpha(isoform synonym)|uniprotkb:TP63(gene name)|psi-mi:TP63(display_short)|uniprotkb:KET(gene name synonym)|uniprotkb:P63(gene name synonym)|uniprotkb:P73H(gene name synonym)|uniprotkb:P73L(gene name synonym)|uniprotkb:TP73L(gene name synonym)|uniprotkb:Chronic ulcerative stomatitis protein(gene name synonym)|uniprotkb:Keratinocyte transcription factor KET(gene name synonym)|uniprotkb:Transformation-related protein 63(gene name synonym)|uniprotkb:Tumor protein p73-like(gene name synonym)|uniprotkb:p40(gene name synonym)|uniprotkb:p51(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Chung et al. (2010) imex:IM-15059|pubmed:20829881|mint:MINT-8040516|doi:10.1038/embor.2010.125 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8298634|mint:MINT-8044440|imex:IM-15059-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N|mint:MINT-8044443(identity) intact:EBI-2337775(isoform-parent)|ensembl:ENSG00000073282(gene)|ensembl:ENST00000354600(transcript)|mint:MINT-8044445(identity) go:"GO:0005634"(nucleus) comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" isoform-comment:"Produced by alternative promoter usage. Variant in position: 6:N->H (in ADULT syndrome)." figure legend:f3c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/09/30 2014/10/16 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:E0nFDEthzDn3LSMqOsn3LNOHKhc9606 intact-crc:A3BD1E30C54C72C2|rigid:RpTEVLxghtxUY8IT2T55rPL2LKc false ha tag:?-?(MINT-8044449) flag tag:?-?(MINT-8044452) - - psi-mi:"MI:0707"(anti tag immunostaining) psi-mi:"MI:0707"(anti tag immunostaining)