#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O14641	uniprotkb:Q155Q3	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	intact:EBI-1104700|uniprotkb:A1A5D8|uniprotkb:Q6P2J8|uniprotkb:Q6PIK4|uniprotkb:Q8IVY4|uniprotkb:Q96N69|uniprotkb:Q9C0C8|ensembl:ENSP00000394352|intact:EBI-2558585|uniprotkb:E9PRV4|uniprotkb:Q86SR7	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:dixc1_human(display_long)|uniprotkb:DIXDC1(gene name)|psi-mi:DIXDC1(display_short)|uniprotkb:CCD1(gene name synonym)|uniprotkb:KIAA1735(gene name synonym)|uniprotkb:DIX domain-containing protein 1(gene name synonym)|uniprotkb:Coiled-coil protein DIX1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kikuchi et al. (2010)	pubmed:20823832|imex:IM-15298|mint:MINT-8080275|doi:10.1038/emboj.2010.221	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8293091|mint:MINT-8080344|imex:IM-15298-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|mint:MINT-8080346(identity)	refseq:NP_001033043.1|refseq:NP_219493.1|ensembl:ENST00000440460(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021869"(forebrain ventricular zone progenitor cell division)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR001158(DIX)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015506(Dishevelled related protein)|ensembl:ENSG00000150764(gene)|interpro:IPR029071|interpro:IPR029800|interpro:IPR038207|rcsb pdb:3PZ7|interpro:IPR036872|refseq:NP_001265471.1|mint:MINT-8080347(identity)	-	-	-	figure legend:f2b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2010/12/14	2014/10/16	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	rogid:U5J1YelDUp6jA2qyvrEUur3rjNI9606	intact-crc:25DA171ADF62DDB5|rigid:eTV8F9aC4Vuyum6Ky8b9A0ppDW8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q155Q3	uniprotkb:O14641	intact:EBI-1104700|uniprotkb:A1A5D8|uniprotkb:Q6P2J8|uniprotkb:Q6PIK4|uniprotkb:Q8IVY4|uniprotkb:Q96N69|uniprotkb:Q9C0C8|ensembl:ENSP00000394352|intact:EBI-2558585|uniprotkb:E9PRV4|uniprotkb:Q86SR7	intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3	psi-mi:dixc1_human(display_long)|uniprotkb:DIXDC1(gene name)|psi-mi:DIXDC1(display_short)|uniprotkb:CCD1(gene name synonym)|uniprotkb:KIAA1735(gene name synonym)|uniprotkb:DIX domain-containing protein 1(gene name synonym)|uniprotkb:Coiled-coil protein DIX1(gene name synonym)	psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kikuchi et al. (2010)	pubmed:20823832|imex:IM-15298|mint:MINT-8080275|doi:10.1038/emboj.2010.221	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8293124|mint:MINT-8081452|imex:IM-15298-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001033043.1|refseq:NP_219493.1|ensembl:ENST00000440460(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021869"(forebrain ventricular zone progenitor cell division)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR001158(DIX)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015506(Dishevelled related protein)|ensembl:ENSG00000150764(gene)|interpro:IPR029071|interpro:IPR029800|interpro:IPR038207|rcsb pdb:3PZ7|interpro:IPR036872|refseq:NP_001265471.1|mint:MINT-8081456(identity)	refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N|mint:MINT-8081454(identity)	-	-	-	figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2010/12/14	2014/10/16	rogid:U5J1YelDUp6jA2qyvrEUur3rjNI9606	rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606	intact-crc:14EC2CDB7DA6EF00|rigid:z3Dn6cKdHlRyz4Ex/A4oO5w74Ug	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q155Q3	uniprotkb:P53350	intact:EBI-1104700|uniprotkb:A1A5D8|uniprotkb:Q6P2J8|uniprotkb:Q6PIK4|uniprotkb:Q8IVY4|uniprotkb:Q96N69|uniprotkb:Q9C0C8|ensembl:ENSP00000394352|intact:EBI-2558585|uniprotkb:E9PRV4|uniprotkb:Q86SR7	intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093	psi-mi:dixc1_human(display_long)|uniprotkb:DIXDC1(gene name)|psi-mi:DIXDC1(display_short)|uniprotkb:CCD1(gene name synonym)|uniprotkb:KIAA1735(gene name synonym)|uniprotkb:DIX domain-containing protein 1(gene name synonym)|uniprotkb:Coiled-coil protein DIX1(gene name synonym)	psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Kikuchi et al. (2010)	pubmed:20823832|imex:IM-15298|mint:MINT-8080275|doi:10.1038/emboj.2010.221	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8293124|mint:MINT-8081452|imex:IM-15298-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001033043.1|refseq:NP_219493.1|ensembl:ENST00000440460(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021869"(forebrain ventricular zone progenitor cell division)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR001158(DIX)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR015506(Dishevelled related protein)|ensembl:ENSG00000150764(gene)|interpro:IPR029071|interpro:IPR029800|interpro:IPR038207|rcsb pdb:3PZ7|interpro:IPR036872|refseq:NP_001265471.1|mint:MINT-8081456(identity)	refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N|mint:MINT-8081460(identity)	-	-	-	figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela_s3)|taxid:9606(Homo sapiens HeLa-S3 cervix carcinoma cell line)	-	2010/12/14	2014/10/16	rogid:U5J1YelDUp6jA2qyvrEUur3rjNI9606	rogid:fBOK366hV6mDprx9IWhz43gPcJE9606	intact-crc:14EC2CDB7DA6EF00|rigid:z3Dn6cKdHlRyz4Ex/A4oO5w74Ug	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)