#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43250	uniprotkb:P43250	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8176923|mint:MINT-8076433|imex:IM-15190-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076435(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076435(identity)	-	comment:"Stoichiometry: 2.0"	comment:"Stoichiometry: 2.0"	comment:mint|figure legend:f1 t1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:B27AFEB4BE7AE380|rigid:FE4TU5a/OSf+XWzIUgBs+VLN+OI	false	-	-	2	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8176941|mint:MINT-8076445|imex:IM-15190-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076467(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076447(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:7D121D320193DD44|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	his tag:c-c(MINT-8076470)|mutation decreasing interaction:3-3(MINT-8076473)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8176980|mint:MINT-8076479|imex:IM-15190-2	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076487(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076481(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:AFF6A923EE3C3F3B|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	his tag:c-c(MINT-8076484)|mutation decreasing interaction:4-4(MINT-8076482)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8176999|mint:MINT-8076492|imex:IM-15190-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076500(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076494(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:9B4A9D9FDA1C1C7B|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	mutation decreasing interaction:6-6(MINT-8076497)|his tag:c-c(MINT-8076495)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8177018|mint:MINT-8076505|imex:IM-15190-4	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076513(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076507(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:811487C1C00C0DDB|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	mutation decreasing interaction:7-7(MINT-8076508)|his tag:c-c(MINT-8076510)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8177087|mint:MINT-8076532|imex:IM-15190-6	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076542(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076534(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:5622363369FE166A|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	his tag:c-c(MINT-8076539)|mutation disrupting interaction:7-7(MINT-8076537)|mutation disrupting interaction:6-6(MINT-8076535)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8177110|mint:MINT-8076548|imex:IM-15190-7	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076558(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076550(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:EDE6B0D7419DC573|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	his tag:c-c(MINT-8076555)|mutation disrupting interaction:9-9(MINT-8076551)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8177129|mint:MINT-8076563|imex:IM-15190-8	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076571(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076565(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:06AF48EB6BEFDBDF|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	mutation disrupting interaction:12-12(MINT-8076568)|his tag:c-c(MINT-8076566)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8177148|mint:MINT-8076575|imex:IM-15190-9	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076583(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076577(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:F72005C74C82635C|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	his tag:c-c(MINT-8076580)|mutation decreasing interaction:13-13(MINT-8076578)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P52205	uniprotkb:P43250	intact:EBI-8176947|uniprotkb:Q17QV8|uniprotkb:Q95134|intact:MINT-8076448|uniprotkb:Q28926|ensembl:ENSBTAP00000001574	intact:EBI-722747|uniprotkb:O60541|uniprotkb:Q13652|ensembl:ENSP00000347655	psi-mi:rom1_bovin(display_long)|uniprotkb:ROM1(gene name)|psi-mi:ROM1(display_short)	psi-mi:grk6_human(display_long)|uniprotkb:G protein-coupled receptor kinase GRK6(gene name synonym)|uniprotkb:GRK6(gene name)|psi-mi:GRK6(display_short)|uniprotkb:GPRK6(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Boguth et al. (2010)	pubmed:20729810|imex:IM-15190|mint:MINT-8076425|doi:10.1038/emboj.2010.206	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8177064|mint:MINT-8076518|imex:IM-15190-5	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061298"(retina vasculature development in camera-type eye)|refseq:NP_776599.2|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0060219"(camera-type eye photoreceptor cell differentiation)|ensembl:ENSBTAG00000001188(gene)|ensembl:ENSBTAT00000001574(transcript)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|interpro:IPR000830(Peripherin/rom-1)|interpro:IPR008952(Tetraspanin)|interpro:IPR018498|interpro:IPR018499|interpro:IPR042026|mint:MINT-8076526(identity)	refseq:NP_001004105.1|refseq:NP_001004106.1|refseq:NP_002073.2|ensembl:ENSG00000198055(gene)|ensembl:ENST00000355472(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|rcsb pdb:2ACX|rcsb pdb:3NYN|rcsb pdb:3NYO|reactome:R-HSA-418555|mint:MINT-8076520(identity)	-	comment:mint	-	figure legend:t2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/11/30	2014/10/16	rogid:IcwJSdDcTc5/dG9mfI4qBhDI6tk9913	rogid:n7nyE4T6CYx5CQdBUyVZha2Hfsc9606	intact-crc:9FE64576D8039714|rigid:d6jRQfPKWcB+utT477/q/TTuczA	false	-	mutation decreasing interaction:6-6(MINT-8076529)|mutation decreasing interaction:7-7(MINT-8076523)|his tag:c-c(MINT-8076521)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)