#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P53676 uniprotkb:Q8R525 intact:EBI-7617505|intact:MINT-7138135 intact:EBI-7048152|intact:MINT-122799 psi-mi:ap3m1_rat(display_long)|uniprotkb:Clathrin assembly protein assembly protein complex 3 mu-1 medium chain(gene name synonym)|uniprotkb:Ap3m1(gene name)|psi-mi:Ap3m1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 47 kDa protein homolog 1(gene name synonym)|uniprotkb:HA1 47 kDa subunit homolog 1(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47 homolog 1(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47 homolog 1(gene name synonym)|uniprotkb:P47A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym) psi-mi:q8r525_rat(display_long) psi-mi:"MI:0029"(cosedimentation through density gradient) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8096808|mint:MINT-8043838|imex:IM-15122-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|mint:P53676|interpro:IPR011012(Longin-like)|rgd:620417|interpro:IPR018240|interpro:IPR022775|interpro:IPR001392(Clathrin adaptor, mu subunit)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4IKN|interpro:IPR036168|mint:MINT-8043846(identity) mint:Q8R525|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0098793"(presynapse)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|mint:MINT-8043848(identity) go:"GO:0005768"(endosome) comment:mint comment:"fragmentation type: fragment"|comment:mint figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2010/09/29 2014/11/01 rogid:hHGHTT5HwVQihfZZGKMJYSB5IFQ10116 rogid:Wf7CrhWRGmhGIVds6LBR3KkFC8A10116 intact-crc:2A3B799A808E4BE3|rigid:BaQysiCMLvJ2ybECyH7GE4Xi/tk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53676 uniprotkb:M0RC99 intact:EBI-7617505|intact:MINT-7138135 intact:EBI-915664|uniprotkb:O88565 psi-mi:ap3m1_rat(display_long)|uniprotkb:Clathrin assembly protein assembly protein complex 3 mu-1 medium chain(gene name synonym)|uniprotkb:Ap3m1(gene name)|psi-mi:Ap3m1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 47 kDa protein homolog 1(gene name synonym)|uniprotkb:HA1 47 kDa subunit homolog 1(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47 homolog 1(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47 homolog 1(gene name synonym)|uniprotkb:P47A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym) psi-mi:rab5a_rat(display_long)|uniprotkb:Rab5a(gene name)|psi-mi:Rab5a(display_short)|uniprotkb:Small GTP-binding protein rab5(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8096808|mint:MINT-8043838|imex:IM-15122-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|mint:P53676|interpro:IPR011012(Longin-like)|rgd:620417|interpro:IPR018240|interpro:IPR022775|interpro:IPR001392(Clathrin adaptor, mu subunit)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4IKN|interpro:IPR036168|mint:MINT-8043846(identity) interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|refseq:NP_073183.1|refseq:XP_003751425.1|refseq:XP_003752788.1|interpro:IPR027417|rgd:620936|mint:M0RC99|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0055037"(recycling endosome)|go:"GO:0098559"(cytoplasmic side of early endosome membrane)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|mint:MINT-8043852(identity) go:"GO:0005768"(endosome) comment:mint - figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2010/09/29 2014/11/01 rogid:hHGHTT5HwVQihfZZGKMJYSB5IFQ10116 rogid:YQ/5pW5C9bIfRqb10F4QJKJXrGI10116 intact-crc:2A3B799A808E4BE3|rigid:BaQysiCMLvJ2ybECyH7GE4Xi/tk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53676 uniprotkb:P09527 intact:EBI-7617505|intact:MINT-7138135 intact:EBI-916225|uniprotkb:Q4AEF6|ensembl:ENSRNOP00000016432 psi-mi:ap3m1_rat(display_long)|uniprotkb:Clathrin assembly protein assembly protein complex 3 mu-1 medium chain(gene name synonym)|uniprotkb:Ap3m1(gene name)|psi-mi:Ap3m1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 47 kDa protein homolog 1(gene name synonym)|uniprotkb:HA1 47 kDa subunit homolog 1(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47 homolog 1(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47 homolog 1(gene name synonym)|uniprotkb:P47A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym) psi-mi:rab7a_rat(display_long)|uniprotkb:Rab7a(gene name)|psi-mi:Rab7a(display_short)|uniprotkb:Ras-related protein p23(gene name synonym)|uniprotkb:Ras-related protein BRL-RAS(gene name synonym)|uniprotkb:Rab7(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8096808|mint:MINT-8043838|imex:IM-15122-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|mint:P53676|interpro:IPR011012(Longin-like)|rgd:620417|interpro:IPR018240|interpro:IPR022775|interpro:IPR001392(Clathrin adaptor, mu subunit)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4IKN|interpro:IPR036168|mint:MINT-8043846(identity) rgd:61908|refseq:NP_076440.1|ensembl:ENSRNOG00000012247(gene)|ensembl:ENSRNOT00000016432(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043195"(terminal bouton)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045453"(bone resorption)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0061724"(lipophagy)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P09527|rcsb pdb:1VG0|rcsb pdb:1VG1|rcsb pdb:1VG8|rcsb pdb:1VG9|reactome:R-RNO-2132295|reactome:R-RNO-6798695|reactome:R-RNO-8854214|reactome:R-RNO-8873719|reactome:R-RNO-8876198|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013405|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013408|reactome:R-RNO-9013423|reactome:R-RNO-9035034|refseq:XP_006236911.1|mint:MINT-8043853(identity) go:"GO:0005768"(endosome) comment:mint - figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2010/09/29 2014/11/01 rogid:hHGHTT5HwVQihfZZGKMJYSB5IFQ10116 rogid:lppyS2rWzk4Iax3nOHVdHiA0ceg10116 intact-crc:2A3B799A808E4BE3|rigid:BaQysiCMLvJ2ybECyH7GE4Xi/tk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P53676 uniprotkb:P62494 intact:EBI-7617505|intact:MINT-7138135 intact:EBI-2112599|uniprotkb:P24410|uniprotkb:Q9JLX1|ensembl:ENSRNOP00000015598 psi-mi:ap3m1_rat(display_long)|uniprotkb:Clathrin assembly protein assembly protein complex 3 mu-1 medium chain(gene name synonym)|uniprotkb:Ap3m1(gene name)|psi-mi:Ap3m1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 47 kDa protein homolog 1(gene name synonym)|uniprotkb:HA1 47 kDa subunit homolog 1(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47 homolog 1(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47 homolog 1(gene name synonym)|uniprotkb:P47A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym) psi-mi:rb11a_rat(display_long)|uniprotkb:Rab11a(gene name)|psi-mi:Rab11a(display_short)|uniprotkb:Rab11(gene name synonym)|uniprotkb:24KG(gene name synonym) psi-mi:"MI:0029"(cosedimentation through density gradient) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8096808|mint:MINT-8043838|imex:IM-15122-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR028565|mint:P53676|interpro:IPR011012(Longin-like)|rgd:620417|interpro:IPR018240|interpro:IPR022775|interpro:IPR001392(Clathrin adaptor, mu subunit)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4IKN|interpro:IPR036168|mint:MINT-8043846(identity) rgd:619762|refseq:NP_112414.1|dip:DIP-46857N|ensembl:ENSRNOG00000011302(gene)|ensembl:ENSRNOT00000015598(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005828"(kinetochore microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008017"(microtubule binding)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010796"(regulation of multivesicular body size)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032402"(melanosome transport)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990182"(exosomal secretion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62494|reactome:R-RNO-432040|reactome:R-RNO-5620912|reactome:R-RNO-5620916|reactome:R-RNO-8854214|reactome:R-RNO-8873719|go:"GO:0045335"(phagocytic vesicle)|mint:MINT-8043854(identity) go:"GO:0005768"(endosome) comment:mint - figure legend:sf2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain) - 2010/09/29 2014/11/01 rogid:hHGHTT5HwVQihfZZGKMJYSB5IFQ10116 rogid:FjkzGzN2VDTyv94M9vD/EJC2qoU10116 intact-crc:2A3B799A808E4BE3|rigid:BaQysiCMLvJ2ybECyH7GE4Xi/tk false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P08911 uniprotkb:P53676 intact:EBI-8096863|intact:MINT-8038781|ensembl:ENSRNOP00000008387 intact:EBI-7617505|intact:MINT-7138135 psi-mi:acm5_rat(display_long)|uniprotkb:Chrm5(gene name)|psi-mi:Chrm5(display_short)|uniprotkb:Chrm-5(gene name synonym) psi-mi:ap3m1_rat(display_long)|uniprotkb:Clathrin assembly protein assembly protein complex 3 mu-1 medium chain(gene name synonym)|uniprotkb:Ap3m1(gene name)|psi-mi:Ap3m1(display_short)|uniprotkb:Mu-adaptin 3A(gene name synonym)|uniprotkb:Mu3A-adaptin(gene name synonym)|uniprotkb:Golgi adaptor AP-1 47 kDa protein homolog 1(gene name synonym)|uniprotkb:HA1 47 kDa subunit homolog 1(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47 homolog 1(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47 homolog 1(gene name synonym)|uniprotkb:P47A(gene name synonym)|uniprotkb:AP-3 adaptor complex mu3A subunit(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit mu-1(gene name synonym) psi-mi:"MI:0096"(pull down) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-8096857|mint:MINT-8038799|imex:IM-15122-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620027|refseq:NP_059058.1|ensembl:ENSRNOG00000006397(gene)|ensembl:ENSRNOT00000008387(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015872"(dopamine transport)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000502(Muscarinic acetylcholine receptor M5)|interpro:IPR000995(Muscarinic acetylcholine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-390648|reactome:R-RNO-416476|mint:MINT-8038801(identity) interpro:IPR028565|mint:P53676|interpro:IPR011012(Longin-like)|rgd:620417|interpro:IPR018240|interpro:IPR022775|interpro:IPR001392(Clathrin adaptor, mu subunit)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4IKN|interpro:IPR036168|mint:MINT-8038804(identity) - comment:mint comment:mint figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/09/29 2014/10/16 rogid:SeKRnUUodNPtHU8hTqBv5i2x8Qw10116 rogid:hHGHTT5HwVQihfZZGKMJYSB5IFQ10116 intact-crc:8FC9A7CEDA197885|rigid:ZxQ4HBg752J7xAYnX4/E3b1LjQQ false binding-associated region:354-413(MINT-8043774)|glutathione s tranferase tag:?-?(MINT-8043771) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P08911 uniprotkb:Q96EV8 intact:EBI-8096863|intact:MINT-8038781|ensembl:ENSRNOP00000008387 intact:EBI-465804|uniprotkb:Q5THY3|uniprotkb:Q5THY4|uniprotkb:Q96NV2|intact:EBI-28986386|ensembl:ENSP00000341680|uniprotkb:Q9H0U2|uniprotkb:Q9H3J5|uniprotkb:A8K3V3 psi-mi:acm5_rat(display_long)|uniprotkb:Chrm5(gene name)|psi-mi:Chrm5(display_short)|uniprotkb:Chrm-5(gene name synonym) psi-mi:dtbp1_human(display_long)|uniprotkb:My031(orf name)|uniprotkb:DTNBP1(gene name)|psi-mi:DTNBP1(display_short)|uniprotkb:Dystrobrevin-binding protein 1(gene name synonym)|uniprotkb:Hermansky-Pudlak syndrome 7 protein(gene name synonym)|uniprotkb:Dysbindin-1(gene name synonym)|uniprotkb:BLOC1S8(gene name synonym)|uniprotkb:Biogenesis of lysosome-related organelles complex 1 subunit 8(gene name synonym) psi-mi:"MI:0096"(pull down) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-8096919|mint:MINT-8046156|imex:IM-15122-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620027|refseq:NP_059058.1|ensembl:ENSRNOG00000006397(gene)|ensembl:ENSRNOT00000008387(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015872"(dopamine transport)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000502(Muscarinic acetylcholine receptor M5)|interpro:IPR000995(Muscarinic acetylcholine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-390648|reactome:R-RNO-416476|mint:MINT-8046158(identity) ensembl:ENSG00000047579(gene)|ensembl:ENST00000344537(transcript)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007596"(blood coagulation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031083"(BLOC-1 complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0005737"(cytoplasm)|go:"GO:0043506"(regulation of JUN kinase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0060159"(regulation of dopamine receptor signaling pathway)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR007531(Dysbindin)|reactome:R-HSA-432722|go:"GO:0048490"(anterograde synaptic vesicle transport)|refseq:NP_115498.2|refseq:NP_898861.1|refseq:NP_001258597.1|refseq:NP_001258598.1|ensembl:ENST00000338950|ensembl:ENSP00000344718|ensembl:ENSP00000341680|refseq:NP_001258596.1|mint:MINT-8046164(identity) - comment:mint - figure legend:f3b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/09/29 2014/10/16 rogid:SeKRnUUodNPtHU8hTqBv5i2x8Qw10116 rogid:PBwxp1vobm9l5yGoqev97lzkMHg9606 intact-crc:C70F0FF458425713|rigid:2zkaz51UeCm8+Elh5B0DvoII5qQ false glutathione s tranferase tag:?-?(MINT-8046161)|binding-associated region:354-413(MINT-8046159) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:B5DFK6 uniprotkb:P09951 intact:EBI-8097016|intact:MINT-8043876|ensembl:ENSRNOP00000025878 intact:EBI-1638487|uniprotkb:Q9WUX7|ensembl:ENSRNOP00000014250 psi-mi:b5dfk6_rat(display_long)|uniprotkb:Ap3d1(gene name)|psi-mi:Ap3d1(display_short)|uniprotkb:rCG_29405(orf name) psi-mi:syn1_rat(display_long)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Synapsin I(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8097009|mint:MINT-8043895|imex:IM-15122-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1308659|refseq:NP_001094189.1|ensembl:ENSRNOG00000018977(gene)|ensembl:ENSRNOT00000025878(transcript)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030424"(axon)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:MINT-8043898(identity) rgd:3797|refseq:NP_001104252.1|refseq:NP_062006.1|ensembl:ENSRNOG00000010365(gene)|ensembl:ENSRNOT00000014250(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:P09951|rcsb pdb:1PK8|rcsb pdb:1PX2|reactome:R-RNO-181429|reactome:R-RNO-212676|mint:MINT-8043897(identity) go:"GO:0045202"(synapse) comment:mint - comment:homomint|comment:mint|figure legend:sf10a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus) - 2010/09/29 2014/10/16 rogid:WbiOMPxeS/2bjeVBzmOb+/uegSc10116 rogid:2Kokx9XJDZPkBHu140QPqsDpSxw10116 intact-crc:433342BBE784133C|rigid:WwKG7eH0IjFWCGvKsyMDGWZ96ps false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P08911 uniprotkb:B5DFK6 intact:EBI-8096863|intact:MINT-8038781|ensembl:ENSRNOP00000008387 intact:EBI-8097016|intact:MINT-8043876|ensembl:ENSRNOP00000025878 psi-mi:acm5_rat(display_long)|uniprotkb:Chrm5(gene name)|psi-mi:Chrm5(display_short)|uniprotkb:Chrm-5(gene name synonym) psi-mi:b5dfk6_rat(display_long)|uniprotkb:Ap3d1(gene name)|psi-mi:Ap3d1(display_short)|uniprotkb:rCG_29405(orf name) psi-mi:"MI:0416"(fluorescence microscopy) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8097066|mint:MINT-8043917|imex:IM-15122-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:620027|refseq:NP_059058.1|ensembl:ENSRNOG00000006397(gene)|ensembl:ENSRNOT00000008387(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007197"(adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015872"(dopamine transport)|go:"GO:0016907"(G protein-coupled acetylcholine receptor activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030425"(dendrite)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000502(Muscarinic acetylcholine receptor M5)|interpro:IPR000995(Muscarinic acetylcholine receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|reactome:R-RNO-390648|reactome:R-RNO-416476|mint:MINT-8043922(identity) rgd:1308659|refseq:NP_001094189.1|ensembl:ENSRNOG00000018977(gene)|ensembl:ENSRNOT00000025878(transcript)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030424"(axon)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:MINT-8043920(identity) - comment:mint comment:mint figure legend:f4e|comment:homomint|comment:mint|comment:After CCh treatment.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-hippocampus_neuron)|taxid:10116(Rattus norvegicus) - 2010/09/29 2014/10/16 rogid:SeKRnUUodNPtHU8hTqBv5i2x8Qw10116 rogid:WbiOMPxeS/2bjeVBzmOb+/uegSc10116 intact-crc:7AD56FA6355934B2|rigid:+QXyH+wCeO96oWvlteYXOVhB/hQ false green fluorescent protein tag:?-?(MINT-8043928) - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0422"(immunostaining) uniprotkb:B5DFK6 uniprotkb:P04177 intact:EBI-8097016|intact:MINT-8043876|ensembl:ENSRNOP00000025878 intact:EBI-7507216|intact:MINT-4585867|ensembl:ENSRNOP00000027682 psi-mi:b5dfk6_rat(display_long)|uniprotkb:Ap3d1(gene name)|psi-mi:Ap3d1(display_short)|uniprotkb:rCG_29405(orf name) psi-mi:ty3h_rat(display_long)|uniprotkb:Th(gene name)|psi-mi:Th(display_short)|uniprotkb:Tyrosine 3-hydroxylase(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Bendor et al. (2010) pubmed:20664521|imex:IM-15122|mint:MINT-8038765|doi:10.1038/emboj.2010.154 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-8097124|mint:MINT-8043905|imex:IM-15122-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:1308659|refseq:NP_001094189.1|ensembl:ENSRNOG00000018977(gene)|ensembl:ENSRNOT00000025878(transcript)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016182"(synaptic vesicle budding from endosome)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030424"(axon)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043195"(terminal bouton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048007"(antigen processing and presentation, exogenous lipid antigen via MHC class Ib)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR010474(Bovine leukaemia virus receptor)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017105(Adaptor protein complex AP-3, delta subunit)|mint:MINT-8043910(identity) go:"GO:0019899"(enzyme binding)|refseq:NP_036872.1|rgd:3853|ensembl:ENSRNOT00000027682(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0004511"(tyrosine 3-monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006585"(dopamine biosynthetic process from tyrosine)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009635"(response to herbicide)|go:"GO:0009651"(response to salt stress)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010038"(response to metal ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0015842"(aminergic neurotransmitter loading into synaptic vesicle)|go:"GO:0016137"(glycoside metabolic process)|go:"GO:0016597"(amino acid binding)|go:"GO:0017085"(response to insecticide)|go:"GO:0018963"(phthalate metabolic process)|go:"GO:0019825"(oxygen binding)|ensembl:ENSRNOG00000020410(gene)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045471"(response to ethanol)|go:"GO:0045472"(response to ether)|go:"GO:0046684"(response to pyrethroid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0050890"(cognition)|go:"GO:0051412"(response to corticosterone)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0052314"(phytoalexin metabolic process)|go:"GO:0070848"(response to growth factor)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071312"(cellular response to alkaloid)|go:"GO:0071316"(cellular response to nicotine)|rcsb pdb:2MDA|rcsb pdb:2TOH|reactome:R-RNO-209905|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:1990384"(hyaloid vascular plexus regression)|interpro:IPR001273(Aromatic amino acid hydroxylase)|interpro:IPR005962(Tyrosine 3-monooxygenase)|interpro:IPR018301|interpro:IPR019773|interpro:IPR019774|interpro:IPR021164|interpro:IPR036329|interpro:IPR036951|interpro:IPR041903|mint:P04177|rcsb pdb:1TOH|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033076"(isoquinoline alkaloid metabolic process)|go:"GO:0033162"(melanosome membrane)|go:"GO:0034617"(tetrahydrobiopterin binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035240"(dopamine binding)|go:"GO:0035690"|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042214"(terpene metabolic process)|go:"GO:0042416"(dopamine biosynthetic process)|go:"GO:0042418"(epinephrine biosynthetic process)|go:"GO:0042421"(norepinephrine biosynthetic process)|go:"GO:0042423"(catecholamine biosynthetic process)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042493"|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0019904"(protein domain specific binding)|mint:MINT-8043908(identity) go:"GO:0030424"(axon) comment:mint comment:mint|comment:homomint|function:Plays an important role in the physiology of adrenergic neurons comment:homomint|comment:mint|figure legend:sf10b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10116(rat-ventral midbrain)|taxid:10116(Rattus norvegicus) - 2010/09/29 2014/10/16 rogid:WbiOMPxeS/2bjeVBzmOb+/uegSc10116 rogid:1tnfhRp4xKaRGRYGgD51S0dLmpU10116 intact-crc:DE6673B65803C9E7|rigid:XAIbDVnzVcMz+XNHGbTbI7d9IZ4 false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)