#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35464	uniprotkb:Q80UG2	intact:EBI-8057848|uniprotkb:Q9EQ71|uniprotkb:Q6P5A8|uniprotkb:Q6PCN9|intact:MINT-7996710|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442	intact:EBI-8057809|intact:MINT-7996686|uniprotkb:E9QN64|uniprotkb:Q8BKK9|uniprotkb:Q5DTW8|ensembl:ENSMUSP00000110748	psi-mi:sem6a_mouse(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)	psi-mi:plxa4_mouse(display_long)|uniprotkb:Plxna4(gene name)|psi-mi:Plxna4(display_short)|uniprotkb:Kiaa1550(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Haklai-Topper et al. (2010)	pubmed:20606624|imex:IM-15009|mint:MINT-7996678|doi:10.1038/emboj.2010.147	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8057804|mint:MINT-7996754|imex:IM-15009-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001298026.1|refseq:NP_061214.2|dip:DIP-59220N|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027231|interpro:IPR036352|rcsb pdb:3AFC|rcsb pdb:3AL8|rcsb pdb:3OKW|rcsb pdb:3OKY|go:"GO:0106089"(negative regulation of cell adhesion involved in sprouting angiogenesis)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051642"(centrosome localization)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|mint:MINT-7996757(identity)	refseq:NP_786926.2|ensembl:ENSMUSG00000029765(gene)|ensembl:ENSMUST00000115096(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0021610"(facial nerve morphogenesis)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0021636"(trigeminal nerve morphogenesis)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0021784"(postganglionic parasympathetic fiber development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021793"(chemorepulsion of branchiomotor axon)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050923"(regulation of negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|rcsb pdb:5L5K|rcsb pdb:5L5L|rcsb pdb:5L5M|rcsb pdb:5L5N|rcsb pdb:7M0R|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|mint:MINT-7996756(identity)	-	comment:mint	comment:mint	comment:mint|figure legend:f4d sf1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/09/15	2014/10/16	rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090	rogid:VQbA7Dwc5J/HFFzXl4mVEbBNkNY10090	intact-crc:5598AFC82812718E|rigid:z3/rzJyuCZkgfj0UqDBgwMqNTS4	false	myc tag:?-?(MINT-7996760)	flag tag:?-?(MINT-7996764)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q80UG2	uniprotkb:O35464	intact:EBI-8057809|intact:MINT-7996686|uniprotkb:E9QN64|uniprotkb:Q8BKK9|uniprotkb:Q5DTW8|ensembl:ENSMUSP00000110748	intact:EBI-8057848|uniprotkb:Q9EQ71|uniprotkb:Q6P5A8|uniprotkb:Q6PCN9|intact:MINT-7996710|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442	psi-mi:plxa4_mouse(display_long)|uniprotkb:Plxna4(gene name)|psi-mi:Plxna4(display_short)|uniprotkb:Kiaa1550(gene name synonym)	psi-mi:sem6a_mouse(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Haklai-Topper et al. (2010)	pubmed:20606624|imex:IM-15009|mint:MINT-7996678|doi:10.1038/emboj.2010.147	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-8057926|mint:MINT-8011786|imex:IM-15009-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_786926.2|ensembl:ENSMUSG00000029765(gene)|ensembl:ENSMUST00000115096(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0021610"(facial nerve morphogenesis)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0021636"(trigeminal nerve morphogenesis)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0021784"(postganglionic parasympathetic fiber development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021793"(chemorepulsion of branchiomotor axon)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050923"(regulation of negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|rcsb pdb:5L5K|rcsb pdb:5L5L|rcsb pdb:5L5M|rcsb pdb:5L5N|rcsb pdb:7M0R|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|mint:MINT-8011788(identity)	refseq:NP_001298026.1|refseq:NP_061214.2|dip:DIP-59220N|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027231|interpro:IPR036352|rcsb pdb:3AFC|rcsb pdb:3AL8|rcsb pdb:3OKW|rcsb pdb:3OKY|go:"GO:0106089"(negative regulation of cell adhesion involved in sprouting angiogenesis)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051642"(centrosome localization)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|mint:MINT-8011792(identity)	-	comment:mint	comment:mint	figure legend:f6d|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2010/09/15	2014/10/16	rogid:VQbA7Dwc5J/HFFzXl4mVEbBNkNY10090	rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090	intact-crc:03AAE60B15DDEC00|rigid:z3/rzJyuCZkgfj0UqDBgwMqNTS4	false	flag tag:?-?(MINT-8011789)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35464	uniprotkb:Q80UG2	intact:EBI-8057848|uniprotkb:Q9EQ71|uniprotkb:Q6P5A8|uniprotkb:Q6PCN9|intact:MINT-7996710|ensembl:ENSMUSP00000019791|ensembl:ENSMUSP00000121442	intact:EBI-8057809|intact:MINT-7996686|uniprotkb:E9QN64|uniprotkb:Q8BKK9|uniprotkb:Q5DTW8|ensembl:ENSMUSP00000110748	psi-mi:sem6a_mouse(display_long)|uniprotkb:Sema6a(gene name)|psi-mi:Sema6a(display_short)|uniprotkb:Semaq(gene name synonym)|uniprotkb:Semaphorin VIA(gene name synonym)|uniprotkb:Semaphorin-6A-1(gene name synonym)|uniprotkb:Semaphorin Q(gene name synonym)	psi-mi:plxa4_mouse(display_long)|uniprotkb:Plxna4(gene name)|psi-mi:Plxna4(display_short)|uniprotkb:Kiaa1550(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Haklai-Topper et al. (2010)	pubmed:20606624|imex:IM-15009|mint:MINT-7996678|doi:10.1038/emboj.2010.147	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8057949|mint:MINT-8011805|imex:IM-15009-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001298026.1|refseq:NP_061214.2|dip:DIP-59220N|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR027231|interpro:IPR036352|rcsb pdb:3AFC|rcsb pdb:3AL8|rcsb pdb:3OKW|rcsb pdb:3OKY|go:"GO:0106089"(negative regulation of cell adhesion involved in sprouting angiogenesis)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|ensembl:ENSMUSG00000019647(gene)|ensembl:ENSMUST00000019791(transcript)|ensembl:ENSMUST00000156422(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030215"(semaphorin receptor binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0048843"(negative regulation of axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051642"(centrosome localization)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|mint:MINT-8011811(identity)	refseq:NP_786926.2|ensembl:ENSMUSG00000029765(gene)|ensembl:ENSMUST00000115096(transcript)|go:"GO:0002116"(semaphorin receptor complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0017154"(semaphorin receptor activity)|go:"GO:0021602"(cranial nerve morphogenesis)|go:"GO:0021610"(facial nerve morphogenesis)|go:"GO:0021612"(facial nerve structural organization)|go:"GO:0021615"(glossopharyngeal nerve morphogenesis)|go:"GO:0021636"(trigeminal nerve morphogenesis)|go:"GO:0021637"(trigeminal nerve structural organization)|go:"GO:0021644"(vagus nerve morphogenesis)|go:"GO:0021784"(postganglionic parasympathetic fiber development)|go:"GO:0021785"(branchiomotor neuron axon guidance)|go:"GO:0021793"(chemorepulsion of branchiomotor axon)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048841"(regulation of axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050923"(regulation of negative chemotaxis)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1902287"(semaphorin-plexin signaling pathway involved in axon guidance)|interpro:IPR001627(Semaphorin/CD100 antigen)|interpro:IPR002165(Plexin)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013548(Plexin cytoplasmic region)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016201(Plexin-like fold)|interpro:IPR031148|interpro:IPR036352|interpro:IPR041019|interpro:IPR041362|rcsb pdb:5L5K|rcsb pdb:5L5L|rcsb pdb:5L5M|rcsb pdb:5L5N|rcsb pdb:7M0R|reactome:R-MMU-399954|reactome:R-MMU-399955|reactome:R-MMU-399956|mint:MINT-8011807(identity)	go:"GO:0005886"(plasma membrane)	comment:mint	comment:mint	figure legend:f4b f4c|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2010/09/15	2014/10/16	rogid:CG0kH0GNVIQHupxGZ+yaHKKf+NQ10090	rogid:VQbA7Dwc5J/HFFzXl4mVEbBNkNY10090	intact-crc:798F2EC69935C754|rigid:z3/rzJyuCZkgfj0UqDBgwMqNTS4	false	myc tag:?-?(MINT-8011812)	flag tag:?-?(MINT-8011808)	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)