#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P05131-1 uniprotkb:P10644 intact:EBI-2930717 intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2930666|imex:IM-15128-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY psi-mi:"MI:0469"(intact) - - figure legend:TABLE 2, Fig 3.|comment:"Only three proteins are clearly visible by colloidal Coomassie Blue staining in the concentrated elution fraction (lane 5)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606 intact-crc:46A3A55F3819E22D|rigid:cae9fkg0L6okhGuJTqwN02SqtHU false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P31323 intact:EBI-2930717 intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2930666|imex:IM-15128-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N psi-mi:"MI:0469"(intact) - - figure legend:TABLE 2, Fig 3.|comment:"Only three proteins are clearly visible by colloidal Coomassie Blue staining in the concentrated elution fraction (lane 5)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606 intact-crc:46A3A55F3819E22D|rigid:cae9fkg0L6okhGuJTqwN02SqtHU false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P13861 intact:EBI-2930717 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2930666|imex:IM-15128-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 2, Fig 3.|comment:"Only three proteins are clearly visible by colloidal Coomassie Blue staining in the concentrated elution fraction (lane 5)."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 intact-crc:46A3A55F3819E22D|rigid:cae9fkg0L6okhGuJTqwN02SqtHU false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P63087 intact:EBI-2930717 intact:EBI-80040|uniprotkb:O09186|uniprotkb:O09189|uniprotkb:P37139|uniprotkb:Q64679|ensembl:ENSMUSP00000099587 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:pp1g_mouse(display_long)|uniprotkb:Ppp1cc(gene name)|psi-mi:Ppp1cc(display_short)|uniprotkb:Protein phosphatase 1C catalytic subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037981|rcsb pdb:4V0U|rcsb pdb:4V0V|rcsb pdb:4V0W|rcsb pdb:4V0X|reactome:R-MMU-141444|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-68877|reactome:R-MMU-9648025|go:"GO:0005856"(cytoskeleton)|ensembl:ENSMUSG00000004455(gene)|ensembl:ENSMUST00000102528(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|refseq:NP_038664.2|refseq:XP_006508478.1|refseq:XP_006530263.1 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:67YjuOIxqIl6Qj+bQnfLBo4iRAg10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P63101 intact:EBI-2930717 intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P63248 intact:EBI-2930717 intact:EBI-2931786|ensembl:ENSMUSP00000028999|ensembl:ENSMUSP00000141466|uniprotkb:P27776|uniprotkb:Q3UTL0 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:ipka_mouse(display_long)|uniprotkb:Pkia(gene name)|psi-mi:Pkia(display_short)|uniprotkb:cAMP-dependent protein kinase inhibitor, muscle/brain isoform(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSMUSG00000027499(gene)|ensembl:ENSMUST00000028999(transcript)|ensembl:ENSMUST00000193330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR004171(cAMP-dependent protein kinase inhibitor)|mint:P63248|rcsb pdb:1APM|rcsb pdb:1ATP|rcsb pdb:1PVK|rcsb pdb:2CPK|rcsb pdb:2GNF|rcsb pdb:2GNG|rcsb pdb:2QUR|rcsb pdb:3FJQ|rcsb pdb:3OW3|rcsb pdb:3QAL|rcsb pdb:3QAM|rcsb pdb:4DFX|rcsb pdb:4DFZ|rcsb pdb:4DG0|rcsb pdb:4DG2|rcsb pdb:4DG3|rcsb pdb:4DH1|rcsb pdb:4DH3|rcsb pdb:4DH5|rcsb pdb:4DH7|rcsb pdb:4DH8|rcsb pdb:4HPT|rcsb pdb:4HPU|rcsb pdb:6F14|rcsb pdb:6Y05|rcsb pdb:6Y0B|rcsb pdb:6Y2O|rcsb pdb:6Y2U|rcsb pdb:6Y89|rcsb pdb:6Y8C|rcsb pdb:6YNA|rcsb pdb:6YNB|rcsb pdb:6YNC|rcsb pdb:6YNR|rcsb pdb:6YNT|rcsb pdb:6YOT|rcsb pdb:6YPP|rcsb pdb:6YQI|rcsb pdb:6YQJ|rcsb pdb:6YQK|refseq:NP_032888.1|dip:DIP-6087N psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:ldgT2f8H/0KJqFA63TWgJ//x0ys10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P70453 intact:EBI-2930717 intact:EBI-2931720|uniprotkb:Q3TFY5|ensembl:ENSMUSP00000088863|uniprotkb:Q9ERB3 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:pde7a_mouse(display_long)|uniprotkb:Pde7a(gene name)|psi-mi:Pde7a(display_short)|uniprotkb:P2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSMUSG00000069094(gene)|ensembl:ENSMUST00000091314(transcript)|go:"GO:0004112"(cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0004115"(3',5'-cyclic-AMP phosphodiesterase activity)|go:"GO:0006198"(cAMP catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023088|interpro:IPR023174|interpro:IPR036971|reactome:R-MMU-418555|refseq:NP_001116231.1|refseq:NP_032828.2 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:/ZeB+6TtTR+qCvHYsWqBCeVhATo10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P31324 intact:EBI-2930717 intact:EBI-455340|uniprotkb:Q3UTZ1|uniprotkb:Q80ZM4|uniprotkb:Q8BRZ7|uniprotkb:B1B199|ensembl:ENSMUSP00000003079|ensembl:ENSMUSP00000039797 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:kap3_mouse(display_long)|uniprotkb:Prkar2b(gene name)|psi-mi:Prkar2b(display_short) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_035288.2|refseq:XP_006515077.1|dip:DIP-31571N|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31324|rcsb pdb:3TNP|rcsb pdb:3TNQ|rcsb pdb:4WBB|rcsb pdb:4X6Q|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-432040|reactome:R-MMU-442720|reactome:R-MMU-5610787|reactome:R-MMU-5620912|reactome:R-MMU-8854518|reactome:R-MMU-983231|ensembl:ENSMUSG00000002997(gene)|ensembl:ENSMUST00000003079(transcript)|ensembl:ENSMUST00000036497(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097546"(ciliary base)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0097338"(response to clozapine)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding) psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:/d/0NSAnglWjmZAcQUn6ATpbJnE10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q8K1M3 intact:EBI-2930717 intact:EBI-2931743|ensembl:ENSMUSP00000035220 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:q8k1m3_mouse(display_long)|uniprotkb:Prkar2a(gene name)|psi-mi:Prkar2a(display_short) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0016301"(kinase activity)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q8K1M3|ensembl:ENSMUSG00000032601(gene)|ensembl:ENSMUST00000035220(transcript)|refseq:NP_032950.1 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:x3JyL96ukOXZMw6spgA4CdElv6M10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P01631 intact:EBI-2930717 intact:EBI-2931761 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:kv2a7_mouse(display_long) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) rcsb pdb:1N4X|go:"GO:0002250"(adaptive immune response)|go:"GO:0003823"(antigen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006955"(immune response)|go:"GO:0019814"(immunoglobulin complex)|interpro:IPR003599(Immunoglobulin subtype)|rcsb pdb:1WZ1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013106(Immunoglobulin V-set)|rcsb pdb:1BFV|rcsb pdb:1CFV|rcsb pdb:1MAJ|rcsb pdb:1MAK|rcsb pdb:1SVZ|rcsb pdb:2BFV|rcsb pdb:2DLF|rcsb pdb:2HKF|rcsb pdb:2HKH|rcsb pdb:2IPT|rcsb pdb:2IQA|rcsb pdb:2O5X|rcsb pdb:2O5Y|rcsb pdb:2O5Z|rcsb pdb:2R0W|rcsb pdb:2VQ1|rcsb pdb:1DLF|interpro:IPR036179 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:/id3e2VMPeAQzTOcGxnJmJ3dnHQ10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q9D6F9 intact:EBI-2930717 intact:EBI-911077|uniprotkb:Q62364|uniprotkb:Q80Y54|ensembl:ENSMUSP00000071135 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:tbb4a_mouse(display_long)|uniprotkb:Tubb4a(gene name)|psi-mi:Tubb4a(display_short)|uniprotkb:Tubb4(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_033477.2|ensembl:ENSMUSG00000062591(gene)|ensembl:ENSMUST00000071135(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0030030"(cell projection organization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0033269"(internode region of axon)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR037103|mint:Q9D6F9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|interpro:IPR036525 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:mMveBNZkQs2x0dyHm/ghVWBe4/410090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P62259 intact:EBI-2930717 intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P05213 intact:EBI-2930717 intact:EBI-2311600|uniprotkb:Q3TY23|uniprotkb:Q3U8B1|uniprotkb:Q3UAW8|uniprotkb:Q4KMW2|ensembl:ENSMUSP00000076777 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:tba1b_mouse(display_long)|uniprotkb:Tuba1b(gene name)|psi-mi:Tuba1b(display_short)|uniprotkb:Tuba2(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_035784.1|ensembl:ENSMUSG00000023004(gene)|ensembl:ENSMUST00000077577(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9013407|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:D4YpuLCXl/S+53qV7P7sF81aARY10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q2M3X8 intact:EBI-2930717 intact:EBI-2931675|ensembl:ENSMUSP00000115207|ensembl:ENSMUSP00000122232|uniprotkb:G5E8P7|uniprotkb:B1B1B5|uniprotkb:B1B1B6|uniprotkb:B1B1B7|uniprotkb:Q80VL9|uniprotkb:Q8C873 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:phar1_mouse(display_long)|uniprotkb:Phactr1(gene name)|psi-mi:Phactr1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSMUSG00000054728(gene)|ensembl:ENSMUST00000128646(transcript)|ensembl:ENSMUST00000149235(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045202"(synapse)|go:"GO:0048870"(cell motility)|go:"GO:0140059"(dendrite arborization)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR004018(RPEL repeat)|interpro:IPR029987|rcsb pdb:4B1U|rcsb pdb:4B1V|rcsb pdb:4B1W|rcsb pdb:4B1X|rcsb pdb:4B1Y|rcsb pdb:4B1Z|refseq:XP_011242697.1|refseq:NP_001005740.1|refseq:XP_017170971.1|refseq:XP_017170972.1|refseq:NP_001289564.1|refseq:NP_001289565.1|refseq:XP_006516968.1|refseq:XP_006516969.1 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:S82qOO2lYBH7U4x+tq9ZTibCim410090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:O88935 intact:EBI-2930717 intact:EBI-775644|uniprotkb:Q62279|uniprotkb:Q8QZT8|ensembl:ENSMUSP00000080568 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:syn1_mouse(display_long)|uniprotkb:Synapsin I(gene name synonym)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Syn-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_001104250.1|refseq:NP_038708.3|ensembl:ENSMUSG00000037217(gene)|ensembl:ENSMUST00000081893(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:O88935|reactome:R-MMU-181429|reactome:R-MMU-212676 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:z48y84jWlS6gOiBDyvxI+aRYzdY10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:A2ALS5 intact:EBI-2930717 intact:EBI-911685|intact:EBI-8316086|intact:MINT-4117429|uniprotkb:E9PZZ8|uniprotkb:Q6A063|uniprotkb:Q80VZ8|uniprotkb:Q8K2L6 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:rpgp1_mouse(display_long)|uniprotkb:Rap1gap(gene name)|psi-mi:Rap1gap(display_short)|uniprotkb:Rap1ga1(gene name synonym)|uniprotkb:ARPP-90(gene name synonym)|uniprotkb:Kiaa0474(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) interpro:IPR003109(GoLoco)|interpro:IPR000331(Rap/ran-GAP)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903697"(negative regulation of microvillus assembly)|go:"GO:1904425"(negative regulation of GTP binding)|go:"GO:1904442"(negative regulation of thyroid gland epithelial cell proliferation)|go:"GO:1990792"(cellular response to glial cell derived neurotrophic factor)|reactome:R-MMU-392517|reactome:R-MMU-8853659|refseq:NP_001074624.1|refseq:NP_083839.1|mint:A2ALS5|refseq:NP_001318144.1|interpro:IPR035974 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:2eFg7zBrcmL26VIIp86Q6c1Q4Xo10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q9Z2A0 intact:EBI-2930717 intact:EBI-400345|uniprotkb:Q9R1D8|uniprotkb:Q9R215|uniprotkb:A6H6U3|ensembl:ENSMUSP00000099991 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:pdpk1_mouse(display_long)|uniprotkb:Pdpk1(gene name)|psi-mi:Pdpk1(display_short)|uniprotkb:Pdk1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_035192.2|ensembl:ENSMUSG00000024122(gene)|ensembl:ENSMUST00000102927(transcript)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004676"(3-phosphoinositide-dependent protein kinase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042995"(cell projection)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033931|interpro:IPR039046|mint:Q9Z2A0|reactome:R-MMU-114604|reactome:R-MMU-1257604|reactome:R-MMU-165158|reactome:R-MMU-202424|reactome:R-MMU-2730905|reactome:R-MMU-2871837|reactome:R-MMU-354192|reactome:R-MMU-389357|reactome:R-MMU-392451|reactome:R-MMU-5218920|reactome:R-MMU-5218921|reactome:R-MMU-5607764|reactome:R-MMU-5625740|reactome:R-MMU-6804757|reactome:R-MMU-9634635|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043304"(regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like) psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:xtiYItB0ax0L6bm4mrjVToLmGZc10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P46460 intact:EBI-2930717 intact:EBI-398006|uniprotkb:A2A646|uniprotkb:Q8BQ65|uniprotkb:Q8C3R2|uniprotkb:Q8CCT9|uniprotkb:Q8CEF0|uniprotkb:Q923C6|ensembl:ENSMUSP00000099364 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:nsf_mouse(display_long)|uniprotkb:Nsf(gene name)|psi-mi:Nsf(display_short)|uniprotkb:Skd2(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:"Suppressor of K(+) transport growth defect 2"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_032766.2|ensembl:ENSMUSG00000034187(gene)|ensembl:ENSMUST00000103075(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46460|reactome:R-MMU-204005|reactome:R-MMU-416993|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811438|reactome:R-MMU-6811440 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:mqNfvBVWEdD4caFZug82c88vwE410090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q6P4S6 intact:EBI-2930717 intact:EBI-2931619|uniprotkb:Q641L5|uniprotkb:Q66JZ5|uniprotkb:Q6ZQ09|uniprotkb:Q8K075|uniprotkb:Q9CYD5 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:sik3_mouse(display_long)|uniprotkb:Sik3(gene name)|psi-mi:Sik3(display_short)|uniprotkb:Kiaa0999(gene name synonym)|uniprotkb:Qsk(gene name synonym)|uniprotkb:Salt-inducible kinase 3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase QSK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001958"(endochondral ossification)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1904515"(positive regulation of TORC2 signaling)|refseq:NP_081774.3|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR034672 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:eIUTh+NVsTk8OSsys+A7gFfS9AM10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P20357 intact:EBI-2930717 intact:EBI-397863|ensembl:ENSMUSP00000109646|uniprotkb:E9QLE1 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:mtap2_mouse(display_long)|uniprotkb:Map2(gene name)|psi-mi:Map2(display_short)|uniprotkb:Mtap2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSMUSG00000015222(gene)|ensembl:ENSMUST00000114013(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043203"(axon hillock)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097442"(CA3 pyramidal cell dendrite)|go:"GO:0150001"(primary dendrite)|go:"GO:0150002"(distal dendrite)|go:"GO:0150014"(apical distal dendrite)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903827"|go:"GO:1904527"(negative regulation of microtubule binding)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990769"(proximal neuron projection)|go:"GO:2000575"(obsolete negative regulation of microtubule motor activity)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR013588(MAP2/Tau projection)|interpro:IPR030797|mint:P20357|refseq:XP_006495817.1|refseq:NP_001297563.1 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:iZ9zGAAalOtaFcgpzAQ80o+lCj010090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P11881 intact:EBI-2930717 intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity) psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q71LX8 intact:EBI-2930717 intact:EBI-2657945 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P63018 intact:EBI-2930717 intact:EBI-433431|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q4FZY7|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:hsp7c_rat(display_long)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) rgd:621725|refseq:NP_077327.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008380"(RNA splicing)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0010045"(response to nickel cation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0044849"(estrous cycle)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990834"(response to odorant)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1CKR|rcsb pdb:1Q2G|rcsb pdb:1UD0|rcsb pdb:2V7Z|rcsb pdb:7HSC|mint:P63018|dip:DIP-33262N psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10116 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q8VDP4 intact:EBI-2930717 intact:EBI-2931660|ensembl:ENSMUSP00000036924|uniprotkb:Q6PIB1|uniprotkb:Q8BWR5|uniprotkb:Q8C0F0|uniprotkb:Q8R3G6 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:ccar2_mouse(display_long)|uniprotkb:Ccar2(gene name)|psi-mi:Ccar2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931605|imex:IM-15128-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSMUSG00000033712(gene)|ensembl:ENSMUST00000035612(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR028811|mint:Q8VDP4|reactome:R-MMU-3371453|refseq:NP_666167.3|refseq:XP_006518959.1 psi-mi:"MI:0469"(intact) - - figure legend:TABLE 3, Fig 4a.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain)|taxid:10090(Mus musculus brain) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:4KqmxaC2o3+yWOF9dwQ9kQ7AMqs10090 intact-crc:55D348A4F4C7FE3F|rigid:aQrWkbpGLGaYmwp1bMZYF5PB0vw false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P84090 intact:EBI-2930717 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931831|imex:IM-15128-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N go:"GO:0005634"(nucleus) - - figure legend:Figs. 5A and B, Table 4.|antagonist:"H89:- an ATP-site competitive PKA-specific small molecule inhibitor, causes a significant decrease of CARP-1 binding."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 intact-crc:04924B7E6C13791B|rigid:vEsVH1O5zk9d1SYxZFPuN5rNnUI false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:P09874 intact:EBI-2930717 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931831|imex:IM-15128-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N go:"GO:0005634"(nucleus) - - figure legend:Figs. 5A and B, Table 4.|antagonist:"H89:- an ATP-site competitive PKA-specific small molecule inhibitor, causes a significant decrease of CARP-1 binding."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 intact-crc:04924B7E6C13791B|rigid:vEsVH1O5zk9d1SYxZFPuN5rNnUI false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05131-1 uniprotkb:Q8IX12 intact:EBI-2930717 intact:EBI-356265|ensembl:ENSP00000265872|uniprotkb:A0JLT7|uniprotkb:A1L4P7|uniprotkb:A8K9D4|uniprotkb:B4DNP8|uniprotkb:B4DRK8|uniprotkb:Q5EBM3|uniprotkb:Q32NE3|uniprotkb:Q5VUP6|uniprotkb:Q6PIZ0|uniprotkb:Q6X935|uniprotkb:Q9H8N4|uniprotkb:Q9NVA7|uniprotkb:Q9NVQ0|uniprotkb:Q9NWM6 psi-mi:p05131-1(display_long)|uniprotkb:Beta-1(isoform synonym)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:ccar1_human(display_long)|uniprotkb:CCAR1(gene name)|psi-mi:CCAR1(display_short)|uniprotkb:CARP1(gene name synonym)|uniprotkb:DIS(gene name synonym)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Death inducer with SAP domain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Erlbruch et al. (2010) imex:IM-15128|pubmed:20564261 taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2931831|imex:IM-15128-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2930698(isoform-parent) ensembl:ENSG00000060339(gene)|ensembl:ENST00000265872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8IX12|reactome:R-HSA-72163|refseq:NP_060707.2|refseq:NP_001269888.1|refseq:NP_001269889.1|dip:DIP-27607N go:"GO:0005634"(nucleus) - - figure legend:Figs. 5A and B, Table 4.|antagonist:"H89:- an ATP-site competitive PKA-specific small molecule inhibitor, causes a significant decrease of CARP-1 binding."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2010/09/30 2014/10/16 rogid:FjUCAIeFW651ijn+aQX6MZrbrVs9913 rogid:YnZve7StC4kAO8raUbp8T02jpe09606 intact-crc:04924B7E6C13791B|rigid:vEsVH1O5zk9d1SYxZFPuN5rNnUI false calmodulin binding peptide plus protein a tag:n-n|flag tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)