#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q61625 uniprotkb:P51881 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-445370|uniprotkb:Q61311|ensembl:ENSMUSP00000016463 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:adt2_mouse(display_long)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:Slc25a5(gene name)|psi-mi:Slc25a5(display_short)|uniprotkb:Ant2(gene name synonym)|uniprotkb:Aac2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_031477.1|dip:DIP-31399N|ensembl:ENSMUSG00000016319(gene)|ensembl:ENSMUST00000016463(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P51881|reactome:R-MMU-83936|go:"GO:0031625"(ubiquitin protein ligase binding) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:146+I0bORlUf6z9chvmdXwUCtOs10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 intact:EBI-2899043 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 - psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:loc97081_mouse_prote(display_short)|psi-mi:EBI-2899043(display_long) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) - psi-mi:"MI:0469"(intact) - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 - intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q3TS89 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2899036 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:q3ts89_mouse(display_long)|uniprotkb:Dipk2a(gene name)|psi-mi:Dipk2a(display_short)|uniprotkb:1190002N15Rik(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) go:"GO:0005576"(extracellular region)|interpro:IPR022049|interpro:IPR020519 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:EACmat6dQSv2cXVNuqySoSTbMwE10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:B0V2N1 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-647877|uniprotkb:Q3TEC3|uniprotkb:Q3TXC9|uniprotkb:Q5XJV4|uniprotkb:Q64503|uniprotkb:Q64699|uniprotkb:Q7TT17|uniprotkb:Q4JFC7|ensembl:ENSMUSP00000064048 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:ptprs_mouse(display_long)|uniprotkb:Ptprs(gene name)|psi-mi:Ptprs(display_short)|uniprotkb:Receptor-type tyrosine-protein phosphatase sigma(gene name synonym)|uniprotkb:PTPNU-3(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_035348.2|refseq:NP_001239382.1|refseq:NP_001239384.1|refseq:NP_001239385.1|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034164"(negative regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048681"(negative regulation of axon regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR036179|mint:B0V2N1|rcsb pdb:3SR9|reactome:R-MMU-388844|reactome:R-MMU-8849932|ensembl:ENSMUSG00000013236(gene)|ensembl:ENSMUST00000067538(transcript)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008201"(heparin binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021510"(spinal cord development) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:ZHccWWvEOOQcSSD7ic6ow6xeqtU10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q925N0 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-775942|uniprotkb:Q8BGG3|ensembl:ENSMUSP00000041872 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:sfxn5_mouse(display_long)|uniprotkb:Sfxn5(gene name)|psi-mi:Sfxn5(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_848754.1|ensembl:ENSMUSG00000033720(gene)|ensembl:ENSMUST00000045846(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0015137"(citrate transmembrane transporter activity)|go:"GO:0015746"(citrate transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q925N0 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:nW6KOlwl7OwaV1yavG+vLVw0p2c10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P62908 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-299793|ensembl:ENSMUSP00000032998|uniprotkb:P17073|uniprotkb:P47933 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:rs3_mouse(display_long)|uniprotkb:Rps3(gene name)|psi-mi:Rps3(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) ensembl:ENSMUSG00000030744(gene)|ensembl:ENSMUST00000032998(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0019901"(protein kinase binding)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|interpro:IPR018280|interpro:IPR036419|mint:P62908|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_036182.1 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:f4Vh6HESE+lKZinjkJ883IG3wiY10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q80XN0 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-773084|uniprotkb:Q3UL45|uniprotkb:Q3UJS9|uniprotkb:Q8BK53|uniprotkb:Q8R0C8|ensembl:ENSMUSP00000087192|ensembl:ENSMUSP00000110881|ensembl:ENSMUSP00000110882 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:bdh_mouse(display_long)|uniprotkb:3-hydroxybutyrate dehydrogenase(gene name synonym)|uniprotkb:Bdh1(gene name)|psi-mi:Bdh1(display_short)|uniprotkb:Bdh(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001116155.1|refseq:NP_780386.3|ensembl:ENSMUSG00000046598(gene)|ensembl:ENSMUST00000089759(transcript)|ensembl:ENSMUST00000115226(transcript)|ensembl:ENSMUST00000115227(transcript)|go:"GO:0003858"(3-hydroxybutyrate dehydrogenase activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0008152"(metabolic process)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q80XN0|reactome:R-MMU-77108|reactome:R-MMU-77111 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:E1f2/RUOR/OJHukOHXp5RolO7Kw10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9D6E4 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794408|uniprotkb:Q8BYN8|ensembl:ENSMUSP00000008088 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:ttc9b_mouse(display_long)|uniprotkb:Ttc9b(gene name)|psi-mi:Ttc9b(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_082693.1|ensembl:ENSMUSG00000007944(gene)|ensembl:ENSMUST00000008088(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:FHz5bE1buurNjUK52l2rET8vsyA10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P14106 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794395|uniprotkb:Q3U793|ensembl:ENSMUSP00000040246 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:c1qb_mouse(display_long)|uniprotkb:C1qb(gene name)|psi-mi:C1qb(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_033907.1|ensembl:ENSMUSG00000036905(gene)|ensembl:ENSMUST00000046384(transcript)|go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048839"(inner ear development)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR037573|mint:P14106|reactome:R-MMU-166663|reactome:R-MMU-173623|reactome:R-MMU-977606 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:foGutZBoR+VSolYUxHhWd55XgOo10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9DB41 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794366|uniprotkb:B2RPU3|uniprotkb:Q14AI5|ensembl:ENSMUSP00000108302 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:ghc2_mouse(display_long)|uniprotkb:Slc25a18(gene name)|psi-mi:Slc25a18(display_short)|uniprotkb:Gc2(gene name synonym)|uniprotkb:"Glutamate/H(+) symporter 2"(gene name synonym)|uniprotkb:Solute carrier family 25 member 18(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001074517.1|refseq:XP_006506712.1|refseq:XP_006506713.1|ensembl:ENSMUSG00000004902(gene)|ensembl:ENSMUST00000112682(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|reactome:R-MMU-428643|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:Ps2cHhKgZS9wzGwVfHr8S3O/1OA10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9CWF2 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794256|uniprotkb:Q3TG26|ensembl:ENSMUSP00000075178 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:tbb2b_mouse(display_long)|uniprotkb:Tubb2b(gene name)|psi-mi:Tubb2b(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_076205.1|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9CWF2|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|ensembl:ENSMUSG00000045136(gene)|ensembl:ENSMUST00000075774(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:sluQMryNuOvp6xlV558+agiRwvE10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P28652 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-397029|uniprotkb:Q5SVH9|ensembl:ENSMUSP00000105438|ensembl:ENSMUSP00000105440 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:kcc2b_mouse(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)|uniprotkb:Camk2d(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_031621.3|ensembl:ENSMUSG00000057897(gene)|ensembl:ENSMUST00000109813(transcript)|ensembl:ENSMUST00000109815(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P28652|reactome:R-MMU-3371571|reactome:R-MMU-399719|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|dip:DIP-31582N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:di/l1bhtPhzeKpErP6iyQfFypBo10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P16858 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P49312 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-642826|uniprotkb:P97312|uniprotkb:Q3V269|ensembl:ENSMUSP00000084609|ensembl:ENSMUSP00000155833 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:roa1_mouse(display_long)|uniprotkb:Hnrpa1(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:HDP-1(gene name synonym)|uniprotkb:Single-strand-binding protein(gene name synonym)|uniprotkb:Topoisomerase-inhibitor suppressed(gene name synonym)|uniprotkb:Hnrnpa1(gene name)|psi-mi:Hnrnpa1(display_short)|uniprotkb:Fli-2(gene name synonym)|uniprotkb:Tis(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_034577.1|ensembl:ENSMUSG00000046434(gene)|ensembl:ENSMUST00000087351(transcript)|ensembl:ENSMUST00000230171(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0035198"(miRNA binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P49312|go:"GO:0008380"(RNA splicing)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:Co5hW3ZlIoa2k56GA2/9RJBNguI10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P10126 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:85G9Uje743KzA02bB/rmKuq2HbU10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q91V61 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-775926|uniprotkb:Q544M7|uniprotkb:Q8C1Z2|ensembl:ENSMUSP00000059419 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:sfxn3_mouse(display_long)|uniprotkb:Sfxn3(gene name)|psi-mi:Sfxn3(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001171483.1|refseq:NP_444427.1|refseq:XP_006527556.1|ensembl:ENSMUSG00000025212(gene)|ensembl:ENSMUST00000062213(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q91V61 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:2SWKs65uF9TnCot4JyNDHb6Bf1I10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9QWI6 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-775592|uniprotkb:O70298 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:srcn1_mouse(display_long)|uniprotkb:p140Cap(gene name synonym)|uniprotkb:SNAP-25-interacting protein(gene name synonym)|uniprotkb:Srcin1(gene name)|psi-mi:Srcin1(display_short)|uniprotkb:Kiaa1684(gene name synonym)|uniprotkb:P140(gene name synonym)|uniprotkb:p130Cas-associated protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_061361.2|interpro:IPR022782|interpro:IPR026727|mint:Q9QWI6|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0098793"(presynapse) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:M3+KJqcvaW0sMG63nFO9CXyjp9Q10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P20152 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid://GDvGAXOR4hUXNtVpnZefex5v410090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q99JR1 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-775916|uniprotkb:Q3UB44|uniprotkb:Q9CZG4|ensembl:ENSMUSP00000021930 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:sfxn1_mouse(display_long)|uniprotkb:Sfxn1(gene name)|psi-mi:Sfxn1(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_081600.1|refseq:XP_006516912.2|refseq:XP_006516913.1|ensembl:ENSMUSG00000021474(gene)|ensembl:ENSMUST00000021930(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006826"(iron ion transport)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042942"(D-serine transport)|go:"GO:0042945"(D-serine transmembrane transporter activity)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q99JR1 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:Fw53Bii/EOp13qU53qI4/06lIaE10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9WUR2 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794295|uniprotkb:Q99M61|uniprotkb:Q9D785|ensembl:ENSMUSP00000131735 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:eci2_mouse(display_long)|uniprotkb:Eci2(gene name)|psi-mi:Eci2(display_short)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Peci(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001103801.1|refseq:NP_035998.2|refseq:XP_006516736.1|refseq:XP_006516737.1|refseq:XP_006516738.1|refseq:XP_006516739.1|refseq:XP_006516740.1|ensembl:ENSMUSG00000021417(gene)|ensembl:ENSMUST00000171229(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|mint:Q9WUR2|reactome:R-MMU-390247|reactome:R-MMU-9033241|go:"GO:0006635"(fatty acid beta-oxidation) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:nHPcS0mXXHwtPjuxHZLEOsf99sk10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q3UGZ9 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794188 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:q3ugz9_mouse(display_long)|uniprotkb:Nrxn2(gene name)|psi-mi:Nrxn2(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:gt35y+O1EXMOUigQ74Ki3iOtyWc10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9R171 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P11214 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794225|uniprotkb:Q6P7U0|uniprotkb:Q91VP2|ensembl:ENSMUSP00000033941 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:tpa_mouse(display_long)|uniprotkb:Plat(gene name)|psi-mi:Plat(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_032898.2|ensembl:ENSMUSG00000031538(gene)|ensembl:ENSMUST00000033941(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006508"(proteolysis)|go:"GO:0009986"(cell surface)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0030141"(secretory granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0060279"(positive regulation of ovulation)|go:"GO:0060468"(prevention of polyspermy)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098992"(neuronal dense core vesicle)|go:"GO:0099183"(trans-synaptic signaling by BDNF, modulating synaptic transmission)|go:"GO:0099544"(perisynaptic space)|interpro:IPR000001(Kringle)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR026280|interpro:IPR033116|interpro:IPR034811|interpro:IPR038178|interpro:IPR043504|reactome:R-MMU-186797|reactome:R-MMU-75205 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:sBaq5KRDVoQf+nrB1j1gYZ/eu+I10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9CS84 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-399696|uniprotkb:O88722|uniprotkb:Q80Y87|uniprotkb:Q8CHE6|uniprotkb:G3UWZ9|ensembl:ENSMUSP00000124116 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:nrx1a_mouse(display_long)|uniprotkb:Nrxn1(gene name)|psi-mi:Nrxn1(display_short)|uniprotkb:Neurexin I-alpha(gene name synonym)|uniprotkb:Kiaa0578(gene name synonym)|uniprotkb:Neurexin-1-alpha(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_064648.3|refseq:NP_796258.2|refseq:XP_006523875.1|refseq:XP_006523874.1|refseq:XP_006523879.1|refseq:NP_001333891.1|ensembl:ENSMUSG00000024109(gene)|ensembl:ENSMUST00000161402(transcript)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099542"(trans-synaptic signaling by endocannabinoid)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789|rcsb pdb:3BOD|rcsb pdb:3MW2|rcsb pdb:6PNP|rcsb pdb:6PNQ|reactome:R-MMU-6794361|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0042297"(vocal learning)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:/fUMo/ju6izl+U1uBzDw5AaJMU010090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q64332 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-775668|uniprotkb:Q6NZR0|uniprotkb:Q9QWV7|ensembl:ENSMUSP00000009538 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:syn2_mouse(display_long)|uniprotkb:Synapsin II(gene name synonym)|uniprotkb:Syn2(gene name)|psi-mi:Syn2(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001104485.1|refseq:NP_038709.1|ensembl:ENSMUSG00000009394(gene)|ensembl:ENSMUST00000009538(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028712|mint:Q64332|reactome:R-MMU-181429|reactome:R-MMU-212676 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:Y/RYUSlblGo1/3HGeKJmfS5yX+M10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q9D6M3 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-445390|uniprotkb:Q3TRY1|ensembl:ENSMUSP00000019226|ensembl:ENSMUSP00000101629|ensembl:ENSMUSP00000144231 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:ghc1_mouse(display_long)|uniprotkb:"Glutamate/H(+) symporter 1"(gene name synonym)|uniprotkb:Solute carrier family 25 member 22(gene name synonym)|uniprotkb:Slc25a22(gene name)|psi-mi:Slc25a22(display_short)|uniprotkb:Gc1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001171047.1|refseq:NP_080922.1|refseq:XP_006536295.1|refseq:XP_006536296.1|ensembl:ENSMUSG00000019082(gene)|ensembl:ENSMUST00000019226(transcript)|ensembl:ENSMUST00000106007(transcript)|ensembl:ENSMUST00000201710(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:Q9D6M3|reactome:R-MMU-428643 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:K98xT2P2uYsFQcZf3ksO3Jb4GU810090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q5F226 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794159|uniprotkb:Q3V1D4|uniprotkb:Q69ZY7|ensembl:ENSMUSP00000067556|ensembl:ENSMUSP00000104492 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:fat2_mouse(display_long)|uniprotkb:Fat2(gene name)|psi-mi:Fat2(display_short)|uniprotkb:Fath2(gene name synonym)|uniprotkb:Kiaa0811(gene name synonym)|uniprotkb:FAT tumor suppressor homolog 2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001025159.1|refseq:XP_006533385.1|refseq:XP_006533386.1|ensembl:ENSMUSG00000055333(gene)|ensembl:ENSMUST00000068853(transcript)|ensembl:ENSMUST00000108864(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002126(Cadherin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:m6EBztiC3YeVv9wA2Z/NBTJ4EnY10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P16330 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-772515|uniprotkb:Q61424|uniprotkb:Q8C7C9|uniprotkb:Q91V42|uniprotkb:Q923F3|ensembl:ENSMUSP00000099409 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:cn37_mouse(display_long)|uniprotkb:Cnp(gene name)|psi-mi:Cnp(display_short)|uniprotkb:Cnp1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001139790.1|refseq:NP_034053.2|refseq:XP_017169734.1|ensembl:ENSMUSG00000006782(gene)|ensembl:ENSMUST00000103120(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P16330|rcsb pdb:2XMI|rcsb pdb:2Y1P|rcsb pdb:2Y3X|rcsb pdb:2YDB|rcsb pdb:2YDC|rcsb pdb:2YDD|rcsb pdb:2YOZ|rcsb pdb:2YP0|rcsb pdb:2YPC|rcsb pdb:2YPE|rcsb pdb:2YPH|rcsb pdb:2YQ9|rcsb pdb:3ZBR|rcsb pdb:3ZBS|rcsb pdb:3ZBZ|rcsb pdb:4WBI|rcsb pdb:4WBL|rcsb pdb:4WC9|rcsb pdb:4WCA|rcsb pdb:4WCB|rcsb pdb:4WCC|rcsb pdb:4WDA|rcsb pdb:4WDB|rcsb pdb:4WDD|rcsb pdb:4WDE|rcsb pdb:4WDF|rcsb pdb:4WDG|rcsb pdb:4WDH|rcsb pdb:4WEX|rcsb pdb:4WFR|rcsb pdb:5AE0 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:z0XniuUAwQzaZTvQmEmctKYNw9810090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q07079 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794324|ensembl:ENSMUSP00000027377 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:ibp5_mouse(display_long)|uniprotkb:Igfbp5(gene name)|psi-mi:Igfbp5(display_short)|uniprotkb:Igfbp-5(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_034648.2|ensembl:ENSMUSG00000026185(gene)|ensembl:ENSMUST00000027377(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007565"(female pregnancy)|go:"GO:0007568"(aging)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016942"(insulin-like growth factor binding protein complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042567"(insulin-like growth factor ternary complex)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043567"(regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043568"(positive regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0043569"(negative regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060416"(response to growth hormone)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1901862"(negative regulation of muscle tissue development)|go:"GO:1904205"(negative regulation of skeletal muscle hypertrophy)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012213(Insulin-like growth factor binding protein 5)|interpro:IPR017891|interpro:IPR022321|interpro:IPR036857|reactome:R-MMU-381426|reactome:R-MMU-8957275 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:7uNxlHgArl44edeAkhxdIu3oW6k10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q91VA7 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-773408|ensembl:ENSMUSP00000028892 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:q91va7_mouse(display_long)|uniprotkb:Idh3b(gene name)|psi-mi:Idh3b(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_570954.1|ensembl:ENSMUSG00000027406(gene)|ensembl:ENSMUST00000028892(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q91VA7|reactome:R-MMU-71403 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:d7ckzD+a/x+uD5i8Sx1YHO8FQGY10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:Q60963 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794278|uniprotkb:Q8BKM3|uniprotkb:Q921T4|ensembl:ENSMUSP00000024706 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:pafa_mouse(display_long)|uniprotkb:Pla2g7(gene name)|psi-mi:Pla2g7(display_short)|uniprotkb:Pafah(gene name synonym)|uniprotkb:PAF 2-acylhydrolase(gene name synonym)|uniprotkb:LDL-associated phospholipase A2(gene name synonym)|uniprotkb:2-acetyl-1-alkylglycerophosphocholine esterase(gene name synonym)|uniprotkb:1-alkyl-2-acetylglycerophosphocholine esterase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_038765.2|refseq:XP_006524428.1|refseq:XP_006524429.1|ensembl:ENSMUSG00000023913(gene)|ensembl:ENSMUST00000024706(transcript)|go:"GO:0003847"(1-alkyl-2-acetylglycerophosphocholine esterase activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034440"(lipid oxidation)|go:"GO:0034441"(plasma lipoprotein particle oxidation)|go:"GO:0034638"(phosphatidylcholine catabolic process)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0062234"(platelet activating factor catabolic process)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR005065(Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II)|interpro:IPR016715(PAF acetylhydrolase)|interpro:IPR029058|reactome:R-MMU-422085 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:RVXoo2tSkq0UV2Ii+D82gPs76Ss10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P08226 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-1634131|ensembl:ENSMUSP00000003066|ensembl:ENSMUSP00000133302|ensembl:ENSMUSP00000133371|ensembl:ENSMUSP00000134160 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:apoe_mouse(display_long)|uniprotkb:Apoe(gene name)|psi-mi:Apoe(display_short) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001292748.1|refseq:NP_001292772.1|refseq:NP_001292773.1|refseq:NP_033826.2|ensembl:ENSMUSG00000002985(gene)|ensembl:ENSMUST00000003066(transcript)|ensembl:ENSMUST00000173739(transcript)|ensembl:ENSMUST00000174064(transcript)|ensembl:ENSMUST00000174355(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002021"(response to dietary excess)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007616"(long-term memory)|go:"GO:0008201"(heparin binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010877"(lipid transport involved in lipid storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016209"(antioxidant activity)|go:"GO:0017038"(protein import)|go:"GO:0019068"(virion assembly)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0032269"(negative regulation of cellular protein metabolic process)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032805"(positive regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034447"(very-low-density lipoprotein particle clearance)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046848"(hydroxyapatite binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0046911"(metal chelating activity)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0051651"(maintenance of location in cell)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061771"(response to caloric restriction)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071830"(triglyceride-rich lipoprotein particle clearance)|go:"GO:0071831"(intermediate-density lipoprotein particle clearance)|go:"GO:0072359"(circulatory system development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0090209"(negative regulation of triglyceride metabolic process)|go:"GO:0090370"(negative regulation of cholesterol efflux)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901627"(negative regulation of postsynaptic membrane organization)|go:"GO:1901631"(positive regulation of presynaptic membrane organization)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902947"(regulation of tau-protein kinase activity)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1902999"(negative regulation of phospholipid efflux)|go:"GO:1903001"(negative regulation of lipid transport across blood-brain barrier)|go:"GO:1903002"(positive regulation of lipid transport across blood-brain barrier)|go:"GO:1905855"(positive regulation of heparan sulfate binding)|go:"GO:1905860"(positive regulation of heparan sulfate proteoglycan binding)|go:"GO:1905890"(regulation of cellular response to very-low-density lipoprotein particle stimulus)|go:"GO:1905906"(regulation of amyloid fibril formation)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1990777"(lipoprotein particle)|go:"GO:2000822"(regulation of behavioral fear response)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P08226|rcsb pdb:1YA9|reactome:R-MMU-3000480|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-8963901|reactome:R-MMU-8964026|reactome:R-MMU-8964058|reactome:R-MMU-975634 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:fJDvqSxzmdZmV8t1M4yp9jw1jvU10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P48962 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-299469|ensembl:ENSMUSP00000034049|uniprotkb:Q62164 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:adt1_mouse(display_long)|uniprotkb:Slc25a4(gene name)|psi-mi:Slc25a4(display_short)|uniprotkb:Anc1(gene name synonym)|uniprotkb:Ant1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:Aac1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) ensembl:ENSMUST00000034049(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P48962|reactome:R-MMU-83936|ensembl:ENSMUSG00000031633(gene)|refseq:NP_031476.3 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:WHXVn/8emywvVfEH5dZ7KrUTiC810090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:P54320 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794207|uniprotkb:Q8C9L8|ensembl:ENSMUSP00000015138 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:eln_mouse(display_long)|uniprotkb:Eln(gene name)|psi-mi:Eln(display_short)|uniprotkb:Tropoelastin(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_031951.2|ensembl:ENSMUSG00000029675(gene)|ensembl:ENSMUST00000015138(transcript)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071953"(elastic fiber)|interpro:IPR003979(Tropoelastin)|reactome:R-MMU-1474228|reactome:R-MMU-1566948|reactome:R-MMU-2129379 psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:nD7OXD7Gj5sBDmd1PMXM+ZTC/cw10090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q61625 uniprotkb:O88531 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-642605|uniprotkb:Q9D681|uniprotkb:Q9WTY3|ensembl:ENSMUSP00000030412 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:ppt1_mouse(display_long)|uniprotkb:Palmitoyl-protein hydrolase 1(gene name synonym)|uniprotkb:Ppt1(gene name)|psi-mi:Ppt1(display_short)|uniprotkb:Ppt(gene name synonym)|uniprotkb:Cln1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794133|imex:IM-14950-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_032943.2|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006898"(receptor-mediated endocytosis)|ensembl:ENSMUSG00000028657(gene)|go:"GO:0006907"(pinocytosis)|ensembl:ENSMUST00000030412(transcript)|go:"GO:0007040"(lysosome organization)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0007625"(grooming behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0015031"(protein transport)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0016790"(thiolester hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031579"(membrane raft organization)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044265"(cellular macromolecule catabolic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0120146"(sulfatide binding)|interpro:IPR002472(Palmitoyl protein thioesterase)|interpro:IPR029058|interpro:IPR030294|reactome:R-MMU-75105|go:"GO:0032429"(regulation of phospholipase A2 activity) psi-mi:"MI:0469"(intact) - - figure legend:Supplementary Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-brain-cerebellum)|taxid:10090(Mus musculus brain cerebellum) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:4dRWzI9cOsETRgn1q2atEkD3Ok410090 intact-crc:C63DD1F60A6E5DF4 false sufficient binding region:399-992 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9R171 uniprotkb:Q61625 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794439|imex:IM-14950-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) psi-mi:"MI:0469"(intact) - - comment:GluRδ2 Interacts with β-NRXN in the Presence of Cbln1|figure legend:Figs. 1D, 2A, 2B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 intact-crc:4C33DBEB23DF3C13|rigid:T7KkvQn4m4FEONz0vNIT7T3D65Y false ha tag:?-? fusion protein:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R171 uniprotkb:P0DI97 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794440|ensembl:ENSMUSP00000133724 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:nrx1b_mouse(display_long)|uniprotkb:Nrxn1(gene name)|psi-mi:Nrxn1(display_short)|uniprotkb:Neurexin I-beta(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794439|imex:IM-14950-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_001333888.1|ensembl:ENSMUSG00000024109(gene)|ensembl:ENSMUST00000174337(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042297"(vocal learning)|go:"GO:0042551"(neuron maturation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090126"(protein-containing complex assembly involved in synapse maturation)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099542"(trans-synaptic signaling by endocannabinoid)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789 psi-mi:"MI:0469"(intact) - - comment:GluRδ2 Interacts with β-NRXN in the Presence of Cbln1|figure legend:Figs. 1D, 2A, 2B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:X9qsm0fsudkhG1om8WWBEMr0b5Q10090 intact-crc:4C33DBEB23DF3C13|rigid:T7KkvQn4m4FEONz0vNIT7T3D65Y false ha tag:?-? v5 tag:?-?|necessary binding region:?-?|sufficient binding region:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R171 uniprotkb:Q61625 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794458|imex:IM-14950-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) psi-mi:"MI:0469"(intact) - - comment:GluRδ2 Interacts with β-NRXN in the Presence of Cbln1|figure legend:Figs. 1D, 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 intact-crc:336AC9A1EE1E9F72 false ha tag:?-? fusion protein:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R171 intact:EBI-2794444 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 - psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:nrx2b_mouse_protein(display_short)|psi-mi:EBI-2794444(display_long) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794458|imex:IM-14950-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) uniprotkb:B2RX09(see-also)|uniprotkb:Q3UGZ9(see-also) psi-mi:"MI:0469"(intact) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Neurexin-2-beta is a set of NRXn2 isoforms produced by alternative promoter usage - proteins currently only in TrEMBL. comment:GluRδ2 Interacts with β-NRXN in the Presence of Cbln1|figure legend:Figs. 1D, 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 - intact-crc:336AC9A1EE1E9F72 false ha tag:?-? v5 tag:?-?|necessary binding region:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R171 uniprotkb:Q61625 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794482|imex:IM-14950-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) psi-mi:"MI:0469"(intact) - - comment:GluRδ2 Interacts with β-NRXN in the Presence of Cbln1|figure legend:Fig. 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 intact-crc:33560F1DC4C2436B|rigid:uaR8ZkRA2XcHzSa0bMK2I3xhncw false ha tag:?-? fusion protein:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R171 uniprotkb:Q8C985 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794478|uniprotkb:E9Q3Q9|ensembl:ENSMUSP00000105757 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:nrx3b_mouse(display_long)|uniprotkb:Nrxn3(gene name)|psi-mi:Nrxn3(display_short)|uniprotkb:Neurexin III-beta(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794482|imex:IM-14950-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0684"(ancillary) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_001239003.1|go:"GO:0001525"(angiogenesis)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789|ensembl:ENSMUSG00000066392(gene)|ensembl:ENSMUST00000110130(transcript) psi-mi:"MI:0469"(intact) - - comment:GluRδ2 Interacts with β-NRXN in the Presence of Cbln1|figure legend:Fig. 2A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:HJAeHLD2vPedLH+UuUUV048Kkz010090 intact-crc:33560F1DC4C2436B|rigid:uaR8ZkRA2XcHzSa0bMK2I3xhncw false ha tag:?-? fusion protein:?-?|necessary binding region:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R171 uniprotkb:Q61625 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794533|imex:IM-14950-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) psi-mi:"MI:0469"(intact) - - comment:Binding of soluble HA-Cbln1 to HEK293T cells transfected with GluRδ2|figure legend:Figs. 3B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 intact-crc:8D8F9C85027CE426|rigid:Bg+ebkRAPgJinGnYTaG71Hvjx+8 false ha tag:?-? fusion protein:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:P0DI97 uniprotkb:Q9R171 intact:EBI-2794440|ensembl:ENSMUSP00000133724 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 psi-mi:nrx1b_mouse(display_long)|uniprotkb:Nrxn1(gene name)|psi-mi:Nrxn1(display_short)|uniprotkb:Neurexin I-beta(gene name synonym) psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794564|imex:IM-14950-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333888.1|ensembl:ENSMUSG00000024109(gene)|ensembl:ENSMUST00000174337(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042297"(vocal learning)|go:"GO:0042551"(neuron maturation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090126"(protein-containing complex assembly involved in synapse maturation)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099542"(trans-synaptic signaling by endocannabinoid)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789 refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) psi-mi:"MI:0469"(intact) - - comment:"Binding of HA-Cbln1 to HEK293T cells transfected with NRXN1β-V5 but not to those transfected with NRXN1β(�S4)-V5."|figure legend:Fig. 4A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:X9qsm0fsudkhG1om8WWBEMr0b5Q10090 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 intact-crc:80E7A2682FC99A8D|rigid:M8+XcBhdFCegA7/vySrqp7RW+5E false v5 tag:?-?|necessary binding region:?-?|sufficient binding region:?-? ha tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) intact:EBI-2794444 uniprotkb:Q9R171 - intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 psi-mi:nrx2b_mouse_protein(display_short)|psi-mi:EBI-2794444(display_long) psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794577|imex:IM-14950-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:B2RX09(see-also)|uniprotkb:Q3UGZ9(see-also) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) psi-mi:"MI:0469"(intact) no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Neurexin-2-beta is a set of NRXn2 isoforms produced by alternative promoter usage - proteins currently only in TrEMBL. - comment:GluRδ2 Interacts with β-NRXN in the Presence of Cbln1|figure legend:Supp. Fig. 4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 - rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 intact-crc:818207A4AFF8422B false v5 tag:?-?|necessary binding region:?-? ha tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9R171 uniprotkb:Q8C985 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794478|uniprotkb:E9Q3Q9|ensembl:ENSMUSP00000105757 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:nrx3b_mouse(display_long)|uniprotkb:Nrxn3(gene name)|psi-mi:Nrxn3(display_short)|uniprotkb:Neurexin III-beta(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-2794588|imex:IM-14950-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_001239003.1|go:"GO:0001525"(angiogenesis)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789|ensembl:ENSMUSG00000066392(gene)|ensembl:ENSMUST00000110130(transcript) psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 4|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:HJAeHLD2vPedLH+UuUUV048Kkz010090 intact-crc:0A7284CE557490F5|rigid:FDcjzRe6eEvmuyRaGX9EvfYjYPw false ha tag:?-? fusion protein:?-?|necessary binding region:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q61625 uniprotkb:Q9R171 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:"MI:0096"(pull down) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794502|imex:IM-14950-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) psi-mi:"MI:0469"(intact) - - comment:Pulldown assay of the interaction of GluRδ2-NTD-Fc and NRXN1β-ECD-AMH in the presence of HA-Cbln1.|figure legend:Fig. 3A, Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 intact-crc:1E289E97EC7564CC|rigid:T7KkvQn4m4FEONz0vNIT7T3D65Y false fusion protein:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q61625 uniprotkb:P0DI97 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 intact:EBI-2794440|ensembl:ENSMUSP00000133724 psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:nrx1b_mouse(display_long)|uniprotkb:Nrxn1(gene name)|psi-mi:Nrxn1(display_short)|uniprotkb:Neurexin I-beta(gene name synonym) psi-mi:"MI:0096"(pull down) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794502|imex:IM-14950-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) refseq:NP_001333888.1|ensembl:ENSMUSG00000024109(gene)|ensembl:ENSMUST00000174337(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042297"(vocal learning)|go:"GO:0042551"(neuron maturation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090126"(protein-containing complex assembly involved in synapse maturation)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099542"(trans-synaptic signaling by endocannabinoid)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789 psi-mi:"MI:0469"(intact) - - comment:Pulldown assay of the interaction of GluRδ2-NTD-Fc and NRXN1β-ECD-AMH in the presence of HA-Cbln1.|figure legend:Fig. 3A, Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/14 2014/10/16 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 rogid:X9qsm0fsudkhG1om8WWBEMr0b5Q10090 intact-crc:1E289E97EC7564CC|rigid:T7KkvQn4m4FEONz0vNIT7T3D65Y false fusion protein:?-? alkaline phosphatase tag:c-c|myc tag:c-c|sufficient binding region:?-?|his tag:c-c|necessary binding region:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R171 uniprotkb:Q61625 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:"MI:0096"(pull down) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794524|imex:IM-14950-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) psi-mi:"MI:0469"(intact) - - comment:"However, NRXN1β(�S4)-ECD-AMH was not coprecipitated by Protein A with GluRδ2-NTD-Fc and HA-Cbln1 (Figure S3A)"|figure legend:Fig. 3C, Supp. Fig. 3A|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 intact-crc:73C2ED46F630DA5B|rigid:Bg+ebkRAPgJinGnYTaG71Hvjx+8 false ha tag:?-? fusion protein:?-?|sufficient binding region:399-992 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P0DI97 uniprotkb:Q9R171 intact:EBI-2794440|ensembl:ENSMUSP00000133724 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 psi-mi:nrx1b_mouse(display_long)|uniprotkb:Nrxn1(gene name)|psi-mi:Nrxn1(display_short)|uniprotkb:Neurexin I-beta(gene name synonym) psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:"MI:0096"(pull down) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794598|imex:IM-14950-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333888.1|ensembl:ENSMUSG00000024109(gene)|ensembl:ENSMUST00000174337(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042297"(vocal learning)|go:"GO:0042551"(neuron maturation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090126"(protein-containing complex assembly involved in synapse maturation)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099542"(trans-synaptic signaling by endocannabinoid)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789 refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) psi-mi:"MI:0469"(intact) - - comment:Pulldown assay of the interaction between NRXN1β-ECD-AMH and HA-Cbln1.|figure legend:Fig. 4B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/14 2014/10/16 rogid:X9qsm0fsudkhG1om8WWBEMr0b5Q10090 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 intact-crc:1C79D029E724E990|rigid:M8+XcBhdFCegA7/vySrqp7RW+5E false alkaline phosphatase tag:c-c|myc tag:c-c|sufficient binding region:?-?|his tag:c-c ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9R171 uniprotkb:Q61625 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 intact:EBI-2794106|uniprotkb:A4QPG1|ensembl:ENSMUSP00000093536 psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:grid2_mouse(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-2794548|imex:IM-14950-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) refseq:NP_032193.1|ensembl:ENSMUST00000095852(transcript)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|ensembl:ENSMUSG00000071424(gene) psi-mi:"MI:0469"(intact) - - comment:"However, NRXN1β(�S4)-ECD-AMH was not coprecipitated by Protein A with GluRδ2-NTD-Fc and HA-Cbln1 (Figure S3A)"|figure legend:Fig. 3C, Supp. Fig. 3A|kinetic_conditions:pH 7.4, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/14 2014/10/16 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 rogid:tGtRvPYFWLcS2DY+O/nGFFgt5/k10090 intact-crc:5A34A64C02C73FC5|rigid:Bg+ebkRAPgJinGnYTaG71Hvjx+8 false ha tag:?-?|his tag:?-? fusion protein:?-?|sufficient binding region:399-992 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0DI97 uniprotkb:Q9R171 intact:EBI-2794440|ensembl:ENSMUSP00000133724 intact:EBI-2794140|uniprotkb:P28655|uniprotkb:Q9QVT5|ensembl:ENSMUSP00000034076|ensembl:ENSMUSP00000126575 psi-mi:nrx1b_mouse(display_long)|uniprotkb:Nrxn1(gene name)|psi-mi:Nrxn1(display_short)|uniprotkb:Neurexin I-beta(gene name synonym) psi-mi:cbln1_mouse(display_long)|uniprotkb:Cbln1(gene name)|psi-mi:Cbln1(display_short)|uniprotkb:Precerebellin(gene name synonym)|uniprotkb:Brain protein D3(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Uemura et al. (2010) imex:IM-14950|pubmed:20537373 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-2794613|imex:IM-14950-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001333888.1|ensembl:ENSMUSG00000024109(gene)|ensembl:ENSMUST00000174337(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030534"(adult behavior)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035176"(social behavior)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042297"(vocal learning)|go:"GO:0042551"(neuron maturation)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090126"(protein-containing complex assembly involved in synapse maturation)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097104"(postsynaptic membrane assembly)|go:"GO:0097105"(presynaptic membrane assembly)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0097112"(gamma-aminobutyric acid receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097116"(gephyrin clustering involved in postsynaptic density assembly)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097119"(postsynaptic density protein 95 clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099054"(presynapse assembly)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099542"(trans-synaptic signaling by endocannabinoid)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001791(Laminin G)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027789 refseq:NP_062600.2|ensembl:ENSMUSG00000031654(gene)|ensembl:ENSMUST00000034076(transcript)|ensembl:ENSMUST00000169693(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009306"(protein secretion)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043083"(synaptic cleft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090394"(negative regulation of excitatory postsynaptic potential)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:0099558"(maintenance of synapse structure)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905703"(negative regulation of inhibitory synapse assembly)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008983(Tumour necrosis factor-like) psi-mi:"MI:0469"(intact) - - comment:"Interaction kinetics was measured by passing various concentrations (0.625, 1.25, 2.5, 5, and 10 μg/ml) of purified HA-Cbln1-His over NRXN1β-ECD-Fc captured on the surface of a sensor chip."|figure legend:Fig. 4C|kinetic_conditions:pH 7.4, Temp=25C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2010/06/14 2014/10/16 rogid:X9qsm0fsudkhG1om8WWBEMr0b5Q10090 rogid:4tHYz0CkFv/+LBPwyEm8vkLbYN810090 intact-crc:5AE5D9441E6B918F|rigid:M8+XcBhdFCegA7/vySrqp7RW+5E false alkaline phosphatase tag:c-c|myc tag:c-c|sufficient binding region:?-?|his tag:c-c ha tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)