#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NYY3	uniprotkb:Q9HC77	intact:EBI-721354|uniprotkb:O60679|uniprotkb:Q96CV7|uniprotkb:Q9UE61|ensembl:ENSP00000274289	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308	psi-mi:plk2_human(display_long)|uniprotkb:Polo-like kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNK(gene name synonym)|uniprotkb:Serum-inducible kinase(gene name synonym)|uniprotkb:PLK2(gene name)|psi-mi:PLK2(display_short)|uniprotkb:SNK(gene name synonym)	psi-mi:cenpj_human(display_long)|uniprotkb:CENPJ(gene name)|psi-mi:CENPJ(display_short)|uniprotkb:CPAP(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:Centrosomal P4.1-associated protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Chang et al. (2010)	pubmed:20531387|imex:IM-15010|mint:MINT-7994481|doi:10.1038/emboj.2010.118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8009135|mint:MINT-7994493|imex:IM-15010-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48943N|refseq:NP_006613.2|refseq:NP_001239155.1|ensembl:ENSG00000145632(gene)|ensembl:ENST00000274289(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007613"(memory)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|interpro:IPR042825|rcsb pdb:4I5M|rcsb pdb:4I5P|rcsb pdb:4I6B|rcsb pdb:4I6F|rcsb pdb:4I6H|rcsb pdb:4RS6|rcsb pdb:4XB0|reactome:R-HSA-6804115|reactome:R-HSA-9662834|mint:MINT-7994496(identity)	refseq:NP_060921.3|dip:DIP-49904N|ensembl:ENSG00000151849(gene)|ensembl:ENST00000381884(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007099"(centriole replication)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0061511"(centriole elongation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR033068|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518|mint:MINT-7994495(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f1a f1b f1c sf1b sf1c sf1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/09/06	2014/10/16	rogid:pjEqMnSG5E6daeauZylX38gmiS09606	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	intact-crc:572527B067E412DA|rigid:KREbfwFvoMiMB8+CsWfCY+ZBHOs	false	binding-associated region:1-390(MINT-7994507)|glutathione s tranferase tag:?-?(MINT-8011916)	glutathione s tranferase tag:?-?(MINT-7994574)|binding-associated region:563-613(MINT-7994571)|mutation decreasing interaction:589-589(MINT-7994517)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9NYY3	uniprotkb:Q9HC77	intact:EBI-721354|uniprotkb:O60679|uniprotkb:Q96CV7|uniprotkb:Q9UE61|ensembl:ENSP00000274289	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308	psi-mi:plk2_human(display_long)|uniprotkb:Polo-like kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNK(gene name synonym)|uniprotkb:Serum-inducible kinase(gene name synonym)|uniprotkb:PLK2(gene name)|psi-mi:PLK2(display_short)|uniprotkb:SNK(gene name synonym)	psi-mi:cenpj_human(display_long)|uniprotkb:CENPJ(gene name)|psi-mi:CENPJ(display_short)|uniprotkb:CPAP(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:Centrosomal P4.1-associated protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Chang et al. (2010)	pubmed:20531387|imex:IM-15010|mint:MINT-7994481|doi:10.1038/emboj.2010.118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8009180|mint:MINT-7994521|imex:IM-15010-4	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48943N|refseq:NP_006613.2|refseq:NP_001239155.1|ensembl:ENSG00000145632(gene)|ensembl:ENST00000274289(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007613"(memory)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|interpro:IPR042825|rcsb pdb:4I5M|rcsb pdb:4I5P|rcsb pdb:4I6B|rcsb pdb:4I6F|rcsb pdb:4I6H|rcsb pdb:4RS6|rcsb pdb:4XB0|reactome:R-HSA-6804115|reactome:R-HSA-9662834|mint:MINT-7994529(identity)	refseq:NP_060921.3|dip:DIP-49904N|ensembl:ENSG00000151849(gene)|ensembl:ENST00000381884(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007099"(centriole replication)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0061511"(centriole elongation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR033068|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518|mint:MINT-7994523(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f1a f1b f1c sf1b sf1c sf1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/09/06	2014/10/16	rogid:pjEqMnSG5E6daeauZylX38gmiS09606	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	intact-crc:C8DF90CF71BABF7E|rigid:KREbfwFvoMiMB8+CsWfCY+ZBHOs	false	binding-associated region:1-390(MINT-7994530)|glutathione s tranferase tag:?-?(MINT-8011919)	binding-associated region:563-613(MINT-7994579)|glutathione s tranferase tag:?-?(MINT-7994577)|mutation decreasing interaction:595-595(MINT-7994524)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9HC77	uniprotkb:O00444	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308	intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861	psi-mi:cenpj_human(display_long)|uniprotkb:CENPJ(gene name)|psi-mi:CENPJ(display_short)|uniprotkb:CPAP(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:Centrosomal P4.1-associated protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Chang et al. (2010)	pubmed:20531387|imex:IM-15010|mint:MINT-7994481|doi:10.1038/emboj.2010.118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8009524|mint:MINT-7994553|imex:IM-15010-6	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060921.3|dip:DIP-49904N|ensembl:ENSG00000151849(gene)|ensembl:ENST00000381884(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007099"(centriole replication)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0061511"(centriole elongation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR033068|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518|mint:MINT-7994555(identity)	refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP|mint:MINT-7994561(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f3a f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/09/06	2014/10/16	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606	intact-crc:ABE49FE9A9569AD8|rigid:NtJf9++S8PxJvz9D4/2I5kVul9U	false	binding-associated region:563-613(MINT-7994587)|mutation disrupting interaction:589-589(MINT-8011935)|mutation disrupting interaction:595-595(MINT-7994556)|glutathione s tranferase tag:?-?(MINT-7994558)	glutathione s tranferase tag:?-?(MINT-8011938)|binding-associated region:1-390(MINT-7994562)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9NYY3	uniprotkb:Q9HC77	intact:EBI-721354|uniprotkb:O60679|uniprotkb:Q96CV7|uniprotkb:Q9UE61|ensembl:ENSP00000274289	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308	psi-mi:plk2_human(display_long)|uniprotkb:Polo-like kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase SNK(gene name synonym)|uniprotkb:Serum-inducible kinase(gene name synonym)|uniprotkb:PLK2(gene name)|psi-mi:PLK2(display_short)|uniprotkb:SNK(gene name synonym)	psi-mi:cenpj_human(display_long)|uniprotkb:CENPJ(gene name)|psi-mi:CENPJ(display_short)|uniprotkb:CPAP(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:Centrosomal P4.1-associated protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	psi-mi:"MI:0424"(protein kinase assay)	Chang et al. (2010)	pubmed:20531387|imex:IM-15010|mint:MINT-7994481|doi:10.1038/emboj.2010.118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-8009465|mint:MINT-7994536|imex:IM-15010-5	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48943N|refseq:NP_006613.2|refseq:NP_001239155.1|ensembl:ENSG00000145632(gene)|ensembl:ENST00000274289(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007613"(memory)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR036947|interpro:IPR042825|rcsb pdb:4I5M|rcsb pdb:4I5P|rcsb pdb:4I6B|rcsb pdb:4I6F|rcsb pdb:4I6H|rcsb pdb:4RS6|rcsb pdb:4XB0|reactome:R-HSA-6804115|reactome:R-HSA-9662834|mint:MINT-7994538(identity)	refseq:NP_060921.3|dip:DIP-49904N|ensembl:ENSG00000151849(gene)|ensembl:ENST00000381884(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007099"(centriole replication)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0061511"(centriole elongation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR033068|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518|mint:MINT-7994542(identity)	-	-	-	comment:homomint|comment:mint|figure legend:f1a f1b f1c sf1b sf1c sf1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2010/09/06	2014/10/16	rogid:pjEqMnSG5E6daeauZylX38gmiS09606	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	intact-crc:0E597C58A48A00AB|rigid:KREbfwFvoMiMB8+CsWfCY+ZBHOs	false	binding-associated region:1-390(MINT-7994539)|glutathione s tranferase tag:?-?(MINT-8011923)	binding-associated region:563-613(MINT-7994584)|glutathione s tranferase tag:?-?(MINT-7994582)|mutation disrupting interaction:595-595(MINT-7994543)|mutation disrupting interaction:589-589(MINT-7994547)	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O43303	uniprotkb:Q9HC77	intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308	psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym)	psi-mi:cenpj_human(display_long)|uniprotkb:CENPJ(gene name)|psi-mi:CENPJ(display_short)|uniprotkb:CPAP(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:Centrosomal P4.1-associated protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Chang et al. (2010)	pubmed:20531387|imex:IM-15010|mint:MINT-7994481|doi:10.1038/emboj.2010.118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8009610|mint:MINT-7994591|imex:IM-15010-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424|mint:MINT-7994603(identity)	refseq:NP_060921.3|dip:DIP-49904N|ensembl:ENSG00000151849(gene)|ensembl:ENST00000381884(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007099"(centriole replication)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0061511"(centriole elongation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR033068|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518|mint:MINT-7994593(identity)	go:"GO:0005813"(centrosome)	-	-	comment:homomint|comment:mint|figure legend:f1d|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/09/06	2014/10/16	rogid:Gvda4RoDRcY+G50iRW5T+haubps9606	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	intact-crc:C3C10CFEB0AF96AC|rigid:vTkblde1sLMbF2vbsZ0ENCTJydk	false	-	myc tag:?-?(MINT-7994596)	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0707"(anti tag immunostaining)
uniprotkb:Q9HC77	uniprotkb:Q66GS9	intact:EBI-946194|uniprotkb:Q2KHM6|uniprotkb:Q5T6R5|uniprotkb:Q96KS5|uniprotkb:Q9C067|uniprotkb:Q5JPD5|ensembl:ENSP00000371308	intact:EBI-1046993|uniprotkb:O75130|uniprotkb:Q9H8H7|uniprotkb:B2RMY0|uniprotkb:Q58F25|ensembl:ENSP00000257287|intact:EBI-1058323	psi-mi:cenpj_human(display_long)|uniprotkb:CENPJ(gene name)|psi-mi:CENPJ(display_short)|uniprotkb:CPAP(gene name synonym)|uniprotkb:LAP(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:Centrosomal P4.1-associated protein(gene name synonym)|uniprotkb:LAG-3-associated protein(gene name synonym)|uniprotkb:LYST-interacting protein 1(gene name synonym)	psi-mi:cp135_human(display_long)|uniprotkb:Centrosomal protein 4(gene name synonym)|uniprotkb:CEP135(gene name)|psi-mi:CEP135(display_short)|uniprotkb:CEP4(gene name synonym)|uniprotkb:KIAA0635(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Chang et al. (2010)	pubmed:20531387|imex:IM-15010|mint:MINT-7994481|doi:10.1038/emboj.2010.118	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-8009644|mint:MINT-7994644|imex:IM-15010-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060921.3|dip:DIP-49904N|ensembl:ENSG00000151849(gene)|ensembl:ENST00000381884(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007099"(centriole replication)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0015631"(tubulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030954"(astral microtubule nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0051301"(cell division)|go:"GO:0060271"(cilium assembly)|go:"GO:0061511"(centriole elongation)|go:"GO:1903724"(positive regulation of centriole elongation)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR009852(T-complex 10/CenJ, C-terminal)|interpro:IPR026581|interpro:IPR033068|mint:Q9HC77|rcsb pdb:5EIB|rcsb pdb:5ITZ|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6804115|reactome:R-HSA-8854518|mint:MINT-7994649(identity)	refseq:NP_079285.2|rcsb pdb:5FCN|rcsb pdb:5NG4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|ensembl:ENSG00000174799(gene)|ensembl:ENST00000257287(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007099"(centriole replication)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1904951"(positive regulation of establishment of protein localization)|interpro:IPR026732|mint:Q66GS9|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-50271N|mint:MINT-7994647(identity)	go:"GO:0005814"(centriole)	-	-	figure legend:f6b|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2010/09/06	2014/10/16	rogid:y2LeLFP5R4hOjDjIkXsY1bZE3IA9606	rogid:x/sbJVIQUS2zD/l2SQsmV5HwKP89606	intact-crc:3B142167A222D124|rigid:SKPM6G5NKRo0kbT56uYQcPBopFs	false	-	-	-	-	psi-mi:"MI:0707"(anti tag immunostaining)	psi-mi:"MI:0422"(immunostaining)